LncTx: A network-based method to repurpose drugs acting on the survival-related lncRNAs in lung cancer
Publication date: Available online 10 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Albert Li, Hsuan-Ting Huang, Hsuan-Cheng Huang, Hsueh-Fen Juan (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 11, 2021 Category: Biotechnology Source Type: research

Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations
Publication date: Available online 10 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Xiaoli An, Qifeng Bai, Zhitong Bing, Huanxiang Liu, Xiaojun Yao (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 11, 2021 Category: Biotechnology Source Type: research

PySTACHIO: Python Single-molecule TrAcking stoiCHiometry Intensity and simulatiOn, a flexible, extensible, beginner-friendly and optimized program for analysis of single-molecule microscopy data
Publication date: Available online 10 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Jack W Shepherd, Ed J Higgins, Adam J M Wollman, Mark C Leake (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 11, 2021 Category: Biotechnology Source Type: research

Beyond Samples: A Metric Revealing More Connections of Gut Microbiota Between Individuals
Publication date: Available online 10 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Zhen Yang, Feng Xu, Hongdou Li, Yungang He (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 11, 2021 Category: Biotechnology Source Type: research

Exploiting the Molecular Basis of Age and Gender Differences in Outcomes of SARS-CoV-2 Infections.
Publication date: Available online 10 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Daniele Mercatelli, Elisabetta Pedace, Pierangelo Veltri, Federico M. Giorgi, Pietro Hiram Guzzi (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 11, 2021 Category: Biotechnology Source Type: research

Genome-scale integration of transcriptome and metabolome unveils squalene synthase and dihydrofolate reductase as targets against AML cells resistant to chemotherapy
Publication date: Available online 8 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Effrosyni Karakitsou, Carles Foguet, Miriam G. Contreras Mostazo, Nina Kurrle, Frank Schnütgen, Martin Michaelis, Jindrich Cinatl, Silvia Marin, Marta Cascante (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 9, 2021 Category: Biotechnology Source Type: research

Machine learning in the prediction of cancer therapy
Publication date: Available online 8 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Raihan Rafique, S.M. Riazul Islam, Julhash U. Kazi (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 9, 2021 Category: Biotechnology Source Type: research

Aqueous ionic liquids redistribute local enzyme stability via long-range perturbation pathways
Publication date: Available online 8 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Till El Harrar, Benedikt Frieg, Mehdi D. Davari, Karl-Erich Jaeger, Ulrich Schwaneberg, Holger Gohlke (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 9, 2021 Category: Biotechnology Source Type: research

De novo genome assembly of the potent medicinal plant Rehmannia glutinosa using nanopore technology
Publication date: Available online 8 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Ligang Ma, Chengming Dong, Chi Song, Xiaolan Wang, Xiaoke Zheng, Yan Niu, Shilin Chen, Weisheng Feng (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 9, 2021 Category: Biotechnology Source Type: research

Magnesium ions regulate mesenchymal stem cells population and osteogenic differentiation: a fuzzy agent-based modeling approach
Publication date: Available online 9 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Jalil Nourisa, Berit Zeller-Plumhoff, Heike Helmholz, Bérengère Luthringer-Feyerabend, Vladimir Ivannikov, Regine Willumeit-Römer (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 9, 2021 Category: Biotechnology Source Type: research

Buffering Updates Enables Efficient Dynamic de Bruijn Graphs
Publication date: Available online 6 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Jarno Alanko, Bahar Alipanahi, Jonathen Settle, Christina Boucher, Travis Gagie (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 7, 2021 Category: Biotechnology Source Type: research

Modelling microbial communities: harnessing consortia for biotechnological applications
Publication date: Available online 3 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Maziya Ibrahim, Lavanya Raajaraam, Karthik Raman (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 3, 2021 Category: Biotechnology Source Type: research

Statistical and machine learning methods for spatially resolved transcriptomics with histology
Publication date: Available online 1 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Jian Hu, Amelia Schroeder, Kyle Coleman, Chixiang Chen, Benjamin J. Auerbach, Mingyao Li (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 2, 2021 Category: Biotechnology Source Type: research

Using bioinformatics approaches to investigate driver genes and identify BCL7A as a prognostic gene in colorectal cancer
Publication date: Available online 1 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Jeffrey Yung-chuan Chao, Hsin-Chuan Chang, Jeng-Kai Jiang, Chih-Yung Yang, Fang-Hsin Chen, Yo-Liang Lai, Wen-Jen Lin, Chia-Yang Li, Shu-Chi Wang, Muh-Hwa Yang, Yu-Feng Lin, Wei-Chung Cheng (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 2, 2021 Category: Biotechnology Source Type: research

Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane
Publication date: Available online 1 July 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Xukai Jiang, Yuliang Sun, Kai Yang, Bing Yuan, Tony Velkov, Lushan Wang, Jian Li (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - July 2, 2021 Category: Biotechnology Source Type: research