PRDM1 rs2185379, unlike BRCA1, is not a prognostic marker in patients with advanced ovarian cancer
CONCLUSIONS: Unlike age at diagnosis, OC histology or gBRCA1 status, rs2185379 in PRDM1 is unlikely a marker of long-term survival in patients with advance OC.PMID:38607753 | DOI:10.3233/CBM-230358 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 12, 2024 Category: Cancer & Oncology Authors: Klara Horackova Michal Vocka Sarka Lopatova Petra Zemankova Zdenek Kleibl Jana Soukupova Source Type: research

PRDM1 rs2185379, unlike BRCA1, is not a prognostic marker in patients with advanced ovarian cancer
CONCLUSIONS: Unlike age at diagnosis, OC histology or gBRCA1 status, rs2185379 in PRDM1 is unlikely a marker of long-term survival in patients with advance OC.PMID:38607753 | DOI:10.3233/CBM-230358 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 12, 2024 Category: Cancer & Oncology Authors: Klara Horackova Michal Vocka Sarka Lopatova Petra Zemankova Zdenek Kleibl Jana Soukupova Source Type: research

PRDM1 rs2185379, unlike BRCA1, is not a prognostic marker in patients with advanced ovarian cancer
CONCLUSIONS: Unlike age at diagnosis, OC histology or gBRCA1 status, rs2185379 in PRDM1 is unlikely a marker of long-term survival in patients with advance OC.PMID:38607753 | DOI:10.3233/CBM-230358 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 12, 2024 Category: Cancer & Oncology Authors: Klara Horackova Michal Vocka Sarka Lopatova Petra Zemankova Zdenek Kleibl Jana Soukupova Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research

Cuproptosis-related gene-located DNA methylation in lower-grade glioma: Prognosis and tumor microenvironment
In this study, we systematically assessed the prognostic value of CRG-located DNA-methylation for lower-grade glioma (LGG). Clinical and molecular data were sourced from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. We employed Cox hazard regression to examine the associations between CRG-located DNA-methylation and OS, leading to the development of a prognostic signature. Kaplan-Meier survival and time-dependent receiver operating characteristic (ROC) analyses were utilized to gauge the accuracy of the signature. Gene Set Enrichment Analysis (GSEA) was applied to uncover potential biological ...
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Liucun Zhu Fa Yuan Xue Wang Rui Zhu Wenna Guo Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research

Cuproptosis-related gene-located DNA methylation in lower-grade glioma: Prognosis and tumor microenvironment
In this study, we systematically assessed the prognostic value of CRG-located DNA-methylation for lower-grade glioma (LGG). Clinical and molecular data were sourced from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. We employed Cox hazard regression to examine the associations between CRG-located DNA-methylation and OS, leading to the development of a prognostic signature. Kaplan-Meier survival and time-dependent receiver operating characteristic (ROC) analyses were utilized to gauge the accuracy of the signature. Gene Set Enrichment Analysis (GSEA) was applied to uncover potential biological ...
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Liucun Zhu Fa Yuan Xue Wang Rui Zhu Wenna Guo Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research

Cuproptosis-related gene-located DNA methylation in lower-grade glioma: Prognosis and tumor microenvironment
In this study, we systematically assessed the prognostic value of CRG-located DNA-methylation for lower-grade glioma (LGG). Clinical and molecular data were sourced from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. We employed Cox hazard regression to examine the associations between CRG-located DNA-methylation and OS, leading to the development of a prognostic signature. Kaplan-Meier survival and time-dependent receiver operating characteristic (ROC) analyses were utilized to gauge the accuracy of the signature. Gene Set Enrichment Analysis (GSEA) was applied to uncover potential biological ...
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Liucun Zhu Fa Yuan Xue Wang Rui Zhu Wenna Guo Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research

Cuproptosis-related gene-located DNA methylation in lower-grade glioma: Prognosis and tumor microenvironment
In this study, we systematically assessed the prognostic value of CRG-located DNA-methylation for lower-grade glioma (LGG). Clinical and molecular data were sourced from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. We employed Cox hazard regression to examine the associations between CRG-located DNA-methylation and OS, leading to the development of a prognostic signature. Kaplan-Meier survival and time-dependent receiver operating characteristic (ROC) analyses were utilized to gauge the accuracy of the signature. Gene Set Enrichment Analysis (GSEA) was applied to uncover potential biological ...
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Liucun Zhu Fa Yuan Xue Wang Rui Zhu Wenna Guo Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research

Cuproptosis-related gene-located DNA methylation in lower-grade glioma: Prognosis and tumor microenvironment
In this study, we systematically assessed the prognostic value of CRG-located DNA-methylation for lower-grade glioma (LGG). Clinical and molecular data were sourced from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. We employed Cox hazard regression to examine the associations between CRG-located DNA-methylation and OS, leading to the development of a prognostic signature. Kaplan-Meier survival and time-dependent receiver operating characteristic (ROC) analyses were utilized to gauge the accuracy of the signature. Gene Set Enrichment Analysis (GSEA) was applied to uncover potential biological ...
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Liucun Zhu Fa Yuan Xue Wang Rui Zhu Wenna Guo Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research

Cuproptosis-related gene-located DNA methylation in lower-grade glioma: Prognosis and tumor microenvironment
In this study, we systematically assessed the prognostic value of CRG-located DNA-methylation for lower-grade glioma (LGG). Clinical and molecular data were sourced from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. We employed Cox hazard regression to examine the associations between CRG-located DNA-methylation and OS, leading to the development of a prognostic signature. Kaplan-Meier survival and time-dependent receiver operating characteristic (ROC) analyses were utilized to gauge the accuracy of the signature. Gene Set Enrichment Analysis (GSEA) was applied to uncover potential biological ...
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Liucun Zhu Fa Yuan Xue Wang Rui Zhu Wenna Guo Source Type: research