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Total 10414 results found since Jan 2013.

Hystricomorph Rodent Analgesia
Limited information on the analgesic efficacy and safety of even clinically commonly used analgesic drugs in guinea pigs and chinchillas is available. Buprenorphine and meloxicam are currently the most common analgesics routinely used to treat painful conditions in guinea pigs and chinchillas. Hydromorphone has also shown to be an effective analgesic drug in these species, with limited adverse effects. Tramadol in chinchillas does not provide analgesia even at high doses, and no information is available on the efficacy of this drug in guinea pigs. Multimodal analgesic protocols should be considered whenever possible.
Source: Veterinary Clinics of North America: Exotic Animal Practice - November 17, 2022 Category: Veterinary Research Authors: Miranda J. Sadar, Christoph Mans Source Type: research

Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction
AbstractRationaleOpioid use disorders are commonly treated by long-acting agonist opioids including methadone and buprenorphine which could affect various aspects of male reproduction especially spermatogenesis.ObjectivesWe aimed to determine whether detoxification with methadone or buprenorphine was associated with reproductive disorders in male mice.MethodsWe orally induced morphine dependence in NMRI male mice, and then performed detoxification programs using either methadone or buprenorphine. Testis architecture and sperm parameters including sperm nuclear DNA integrity, mitochondrial activity, oxidative stress in semi...
Source: Psychopharmacology - November 17, 2022 Category: Psychiatry Source Type: research

BUPRENORPHINE AND NALOXONE (buprenorphine hydrochloride and naloxone hydrochloride) tablet Golden State Medical Supply, Inc.
Updated Date: Wed, 16 Nov 2022 00:00:00 EST
Source: DailyMed Drug Label Updates - November 16, 2022 Category: Drugs & Pharmacology Source Type: alerts

Differences between users ’ and addiction medicine experts’ harm and benefit assessments of licit and illicit psychoactive drugs: Input for psychoeducation and legalization/restriction debates
ConclusionThis study addressed current trends of psychoactive substance abuse (e.g., synthetic cannabinoids, prescription drugs) and provides from both perspectives (that of the user and that of the addiction medicine experts) robust harm/benefit evaluations at least of a core group of psychoactive substances (traditional illicit psychoactive substances, cannabis, methadone, alcohol and nicotine). The results of this study can be valuable to the psychoeducation of substance-addicted individuals and to current restriction/legalization debates, especially in the Western-EU.
Source: Frontiers in Psychiatry - November 16, 2022 Category: Psychiatry Source Type: research

Cannabis use and opioid relapse: An exploratory survival analysis of prospectively collected data
ConclusionOur analysis failed to show cannabis to be protective against relapse to opioid use in patients receiving buprenorphine-naloxone for OUD. We identified that individuals who inject drugs, are on higher doses of buprenorphine-naloxone, or have been in treatment for less than two years have a higher hazard for relapse. The presence of such factors may thus warrant closer patient follow-up and more stringent treatment protocols to mitigate risk of relapse and potential overdose.
Source: Frontiers in Psychiatry - November 16, 2022 Category: Psychiatry Source Type: research

Investigation of the effects of opioids on microglial nitrite and nitric oxide synthase (iNOS) production and phagocytosis during inflammation
CONCLUSION: Buprenorphine and salvinorin A were found to reduce NO production and iNOS induction in microglial cells activated by LPS and IFN-γ. Salvinorin A promoted the phagocytosis of microglia cells treated by LPS.PMID:36372918 | DOI:10.2174/1386207326666221111093915
Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2022 Category: Chemistry Authors: Yi Zhou Xihua Lu Yunfei Zhang Changsheng Li Yu Bai Zhen Zhang Source Type: research

Qualitative exploration of the psychological dimensions of telehealth shared medical appointments (SMAs) for buprenorphine prescribing
Source: Journal of Addictive Diseases - November 14, 2022 Category: Addiction Authors: Ben Greenberg Anna C Lauren Lucitt Nancy A. Haug Anna Lembke Source Type: research

Impact of prerelease methadone on mortality among people with HIV and opioid use disorder after prison release: results from a randomized and participant choice open-label trial in Malaysia
Mortality is elevated after prison release and may be higher in people with HIV and opioid use disorder (OUD). Maintenance with opioid agonist therapy (OAT) like methadone or buprenorphine reduces mortality in...
Source: BMC Infectious Diseases - November 11, 2022 Category: Infectious Diseases Authors: Alexander R. Bazazi, Gabriel J. Culbert, Martin P. Wegman, Robert Heimer, Adeeba Kamarulzaman and Frederick L. Altice Tags: Research Source Type: research

Efficacy of Transdermal Buprenorphine Patch in Postoperative Pain Management in Oral and Maxillofacial Surgery
ConclusionBuprenorphine has high analgesic potential, good safety profile, ease of opioids switches and reversibility by μ- antagonist. Transdermal route is cost effective and has increased patient compliance and ease of handling with less adverse effects. Thus, the efficacy of transdermal buprenorphine in postoperative pain management was good.
Source: Journal of Maxillofacial and Oral Surgery - November 11, 2022 Category: ENT & OMF Source Type: research

Updated Date: Thu, 10 Nov 2022 00:00:00 EST
Source: DailyMed Drug Label Updates - November 10, 2022 Category: Drugs & Pharmacology Source Type: alerts

Screening and Brief Intervention for Cannabis Misuse in Individuals on Buprenorphine Treatment for Opioid Use Disorder: Double-Blind Randomized Clinical Trial
Source: Journal of Psychoactive Drugs - November 10, 2022 Category: Psychiatry & Psychology Authors: Babita Sharma Abhishek Ghosh Renjith R Pillai Debasish Basu Source Type: research

Medication Treatment for Addiction Is Shorter for Black and Hispanic Patients, Study Finds
The analysis of 15 years of prescription data showed that the racial disparities are widening.
Source: NYT Health - November 9, 2022 Category: Consumer Health News Authors: Emily Baumgaertner Tags: your-feed-science Buprenorphine (Drug) Research Drugs (Pharmaceuticals) Race and Ethnicity Hispanic-Americans Minorities Black People Opioids and Opiates Addiction (Psychology) Whites Drug Abuse and Traffic United States Source Type: news

BUPRENORPHINE HCL tablet Major Pharmaceuticals
Updated Date: Wed, 09 Nov 2022 00:00:00 EST
Source: DailyMed Drug Label Updates - November 9, 2022 Category: Drugs & Pharmacology Source Type: alerts