Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: a meta-analysis in Europeans
Conclusion
Our study indicates a potential beneficial effect of LLD and antidiabetic drug use on prevalence of AMD across multiple European cohorts. Our findings support the importance of metabolic processes in the multifactorial aetiology of AMD. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Mauschitz, M. M., Verzijden, T., Schuster, A. K., Elbaz, H., Pfeiffer, N., Khawaja, A., Luben, R. N., Foster, P. J., Rauscher, F. G., Wirkner, K., Kirsten, T., Jonas, J. B., Bikbov, M. M., Hogg, R., Peto, T., Cougnard-Gregoire, A., Bertelsen, G., Erke, M. Tags: Press releases Original articles - Clinical science Source Type: research
Prevalence and risk factors for age-related macular degeneration in a population-based cohort study of older adults in Northern Ireland using multimodal imaging: NICOLA Study
Conclusions
Multimodal imaging-based classification has provided evidence of some divergence of genetic risk associations between classical drusen and SDD. Our findings support an urgent review of current AMD severity classification systems. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Hogg, R. E., Wright, D. M., Quinn, N. B., Muldrew, K. A., Hamill, B., Smyth, L., McKnight, A. J., Woodside, J., Tully, M. A., Cruise, S., McGuinness, B., Young, I. S., Kee, F., Peto, T., Chakravarthy, U. Tags: Open access Original articles - Clinical science Source Type: research
Macular thickness and its associated factors in a Chinese rural adult population: the Handan Eye Study
Conclusions
This study finds that RT in central macula is the thinnest, followed by the outer ring, the RT in the inner ring is the thickest. Age and gender are related to RT. These associated factors need to be considered when explaining RT. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Wu, J., Lin, C., Du, Y., Fan, S. J., Pan, L., Pan, Q., Cao, K., Wang, N. Tags: Open access Original articles - Clinical science Source Type: research
Automated segmentation of ultra-widefield fluorescein angiography of diabetic retinopathy using deep learning
Conclusions
DL models can detect NV and NP as well as disc and outer margins on UWFA with good performance. This automated segmentation of important UWFA features will aid physicians in DR clinics and in overcoming grader subjectivity. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Lee, P.-K., Ra, H., Baek, J. Tags: Original articles - Clinical science Source Type: research
Automatic interpretation and clinical evaluation for fundus fluorescein angiography images of diabetic retinopathy patients by deep learning
Conclusion
This is the first study to do automated standardised labelling on FFA images. Our model is able to be applied in clinical practice, and will make great contributions to the development of intelligent diagnosis of FFA images. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Gao, Z., Pan, X., Shao, J., Jiang, X., Su, Z., Jin, K., Ye, J. Tags: Original articles - Clinical science Source Type: research
Formal registration of visual impairment in people with diabetic retinopathy significantly underestimates the scale of the problem: a retrospective cohort study at a tertiary care eye hospital service in the UK
Conclusion
The majority of people with vision impairment are not registered at the point of care, which could translate to underestimation of diabetes-related VI and all-cause VI at a national level if replicated at other centres. Further work is needed to explore rates of VI and uptake of registration. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Olvera-Barrios, A., Mishra, A. V., Schwartz, R., Khatun, M., Seltene, M., Rutkowska, C., Rudnicka, A. R., Owen, C. G., Tufail, A., A Egan, C. Tags: Original articles - Clinical science Source Type: research
Two-year recall for people with no diabetic retinopathy: a multi-ethnic population-based retrospective cohort study using real-world data to quantify the effect
We examined the potential effect of biennial versus annual screening on the detection of sight-threatening diabetic retinopathy (STDR) and proliferative diabetic retinopathy (PDR) among PLD without DR from a large urban multi-ethnic English DESP.
Methods
PLD in North-East London DESP (January 2012 to December 2021) with no DR on two prior consecutive screening visits with up to 8 years of follow-up were examined. Annual STDR and PDR incidence rates, overall and by ethnicity, were quantified. Delays in identification of STDR and PDR events had 2-year screening intervals been used were determined.
Findings
Among 82 782 PLD...
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Olvera-Barrios, A., Rudnicka, A. R., Anderson, J., Bolter, L., Chambers, R., Warwick, A. N., Welikala, R., Fajtl, J., Barman, S., Remgnino, P., Wu, Y., Lee, A. Y., Chew, E. Y., Ferris, F. L., Hingorani, A., Sofat, R., A. Egan, C., Tufail, A., Owen, C. G., Tags: Open access, Press releases Original articles - Clinical science Source Type: research
Electroretinographic findings in retinal vasculitis
Conclusion
In this study, RV was not frequently associated with severe global retinal dysfunction Higher FFA scores, and vitreous haze grading were weakly, but significantly, correlated with cone-generated ffERG responses. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Ghoraba, H. H., Matsumiya, W., Or, C., Khojasteh, H., Patel, P., Karaca, I., Regenold, J., Zaidi, M., Hwang, J., Lajevardi, S., Yavari, N., Than, N. T. T., Park, S. W., Akhavanrezayat, A., Uludag, G., Yasar, C., Leung, L.-S. B., Nguyen, Q. D. Tags: Original articles - Clinical science Source Type: research
Association of macular vessel density and ganglion cell complex thickness with central visual field progression in glaucoma
Conclusions
Lower macular VD and GCC were associated with faster worsening of CVF, and lower macular VD was associated with increased odds of CVF progression. Assessment of macular OCT and OCTA may help detect glaucoma eyes with CVF progression. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Wu, J.-H., Moghimi, S., Nishida, T., Mahmoudinezhad, G., M Zangwill, L., Weinreb, R. N. Tags: Original articles - Clinical science Source Type: research
Long-term surgical outcomes of Aurolab aqueous drainage implant in pediatric eyes with primary congenital glaucoma versus aphakic glaucoma
Conclusions
Eyes with APG had relatively better outcomes after AADI placement compared with PCG during 4 years of follow-up. Reoperations accounted for more than 70% of the failures. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Puthuran, G. V., Ramesh, S., Maheswari, P., Reddy, M. M., S, M. S. U., Krishnadas, S. R., Gedde, S. J. Tags: Original articles - Clinical science Source Type: research
Risk factors associated with abandonment of care in retinoblastoma: analysis of 692 patients from 10 countries
Conclusion
Country, advanced disease and female sex were all associated with higher rates of abandonment. In this analysis, enucleation as the primary treatment was not associated with abandonment. Further research investigating cultural barriers can enable the building of targeted retention strategies unique to each country. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Nishath, T., Li, X., Chandramohan, A., Othus, M., Ji, X., Zou, Y., Sultana, S., Rashid, R., Sherief, S. T., Cassoux, N., Garcia Leon, J. L., Diaz Coronado, R., Lopez, A. M. Z., Ushakova, T. L., Polyakov, V. G., Roy, S. R., Ahmad, A., Reddy, A., Sagoo, M. Tags: Original articles - Clinical science Source Type: research
Effect of atropine, orthokeratology and combined treatments for myopia control: a 2-year stratified randomised clinical trial
Conclusions
Atropine combined with ortho-k treatment can improve the efficacy of myopia control compared with monotherapy in children aged 8–12. Younger children might benefit more from ortho-k.
Trial registration number
ChiCTR1800015541. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Xu, S., Li, Z., Zhao, W., Zheng, B., Jiang, J., Ye, G., Feng, Z., Long, W., He, L., He, M., Hu, Y., Yang, X. Tags: Original articles - Clinical science Source Type: research
Effect of spectacle lenses with aspherical lenslets on choroidal thickness in myopic children: a 2-year randomised clinical trial
Conclusions
The ChT of the macula decreased after 2 years of myopia progression with SVL. Wearing spectacle lenses with aspherical lenslets reduced or abolished the ChT thinning and HAL had a more pronounced effect.
Trial registration number
ChiCTR1800017683. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Huang, Y., Li, X., Wu, J., Huo, J., Zhou, F., Zhang, J., Yang, A., Spiegel, D. P., Chen, H., Bao, J. Tags: Open access Original articles - Clinical science Source Type: research
Prevalence of myopia and uncorrected myopia among 721 032 schoolchildren in a city-wide vision screening in southern China: the Shantou Myopia Study
Conclusion
The overall prevalence of myopia among schoolchildren in Shantou was 51.8%, higher than the national average in China. The proportion of uncorrected myopia is high, especially in primary schools. Our results indicate the need for public education on eye care among schoolchildren even in a municipal city. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Wang, H., Li, Y., Qiu, K., Zhang, R., Lu, X., Luo, L., Lin, J.-W., Lu, Y., Zhang, D., Guo, P., Yang, Y., Jing, L., Huang, Y., Ma, Q., Zhou, R., Ou, Y., Chen, Q., Zhou, Y., Deng, D., Li, C., Yam, J. C., Chen, L. J., Pang, C.-P., Zhang, M. Tags: Original articles - Clinical science Source Type: research
Modelling ready-made spectacle coverage for children and adults using a large global database
Conclusion
Despite their advantages in cost and convenience, coverage delivered by RMS is limited under current prescribing guidelines, particularly for children and presbyopic adults. Interchangeable designs do little to remediate this, despite extending coverage for anisometropia. Our free application allows users to estimate RMS coverage in specific target populations. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - November 22, 2023 Category: Opthalmology Authors: Chan, V. F., Wright, D. M., Mavi, S., Dabideen, R., Smith, M., Sherif, A., Congdon, N. Tags: Open access Original articles - Clinical science Source Type: research
