Longitudinal associations between self-reported vision impairment and all-cause mortality: a nationally representative cohort study among older Chinese adults
Conclusions
Both pre-existing and new self-reported VI increase all-cause mortality among Chinese adults aged 45 years and older, though visual correction reduces this risk. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Wang, Z., Congdon, N., Ma, X. Tags: Open access Original articles - Clinical science Source Type: research
Associations between visual impairment, incident falls and fall frequency among older asians: longitudinal findings from the Singapore Epidemiology of Eye Diseases study
Conclusions
Baseline bilateral but not unilateral VI conferred nearly two-fold higher odds of incident fall. Importantly, even mild unilateral VI conferred a substantially greater likelihood of frequent falls from correctable and uncorrectable conditions. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Gupta, P., Man, R. E. K., Fenwick, E. K., Qian, C., Sim, R., Majithia, S., Tham, Y. C., Sabanayagam, C., Wong, T. Y., Cheng, C.-Y., Lamoureux, E. L. Tags: Editor's choice Original articles - Clinical science Source Type: research
Visual loss in surgical retinal disease: retinal imaging and photoreceptor cell counts
Vision loss after detachment of the neurosensory retina is a complex process which is not fully understood. Clinical factors have been identified which contribute to loss of macular function after retinal detachment and laboratory studies have played an important role in understanding the cellular and subcellular pathological processes which underlie the loss of visual function. As clinical imaging has advanced, multiple studies have focused on identifying and correlating clinicopathological features with visual outcomes in patients with rhegmatogenous retinal detachment. Optical coherence tomography, fundus autofluorescen...
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Anguita, R., Charteris, D. Tags: Review Source Type: research
At a glance
Associations between visual impairment, incident falls and fall frequency among older Asians: longitudinal findings from the Singapore Epidemiology of Eye Diseases Study (see page 1590) Baseline bilateral but not unilateral visual impairment (VI) conferred nearly two-fold higher odds of any incident fall. In those who had fallen at least once, it is of interest that having even mild unilateral VI conferred a substantially greater likelihood of further falls. Longitudinal associations between self-reported vision impairment and all-cause mortality: a nationally representative cohort study among older Chinese adults (see pag...
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Larkin, F. Tags: Open access Highlights from this issue Source Type: research
Urocortin-positive nerve fibres and cells are present in the human choroid
Conclusion
UCN is part of the choroidal innervation. UCN+/VAChT+ fibres could derive from the few cells of the PPG or cells of the CIL, if these indeed supply the choroid. UCN+/SP+ fibres might originate from ICN, or the few UCN+ cells detected in the TRI. Further studies are necessary to establish UCN function in the choroid and its implication for choroidal autonomic control. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Kaser-Eichberger, A., Platzl, C., Wolfmeier, H., Trost, A., Horn, A., Barnerssoi, M., Strohmaier, C., Schroedl, F. Tags: Original articles - Laboratory science Source Type: research
Hand grip strength and ocular associations: the Ural Eye and Medical Study
Conclusions and relevance
In addition to parameters such as lower physical activity, higher depression score and worse general health status, a reduced HGS is associated with visual impairment, shorter axial length, lower intraocular pressure, thinner peripapillary retinal nerve fibre layer and higher prevalence of diabetic retinopathy. HGS dynamometry or a handshake may provide the ophthalmologist additional clinical information about the general health and ocular parameters of the patient. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Bikbov, M. M., Zainullin, R. M., Gilmanshin, T. R., Iakupova, E. M., Kazakbaeva, G. M., Panda-Jonas, S., Tuliakova, A. M., Fakhretdinova, A. A., Gilemzianova, L. I., Jonas, J. B. Tags: Original articles - Clinical science Source Type: research
Predicting the risk of distant and local recurrence for patients with ocular adnexal extranodal marginal zone lymphoma: a matched case-control study
Conclusion
Our analyses suggested DR and LR as two distinct prognostic events, and additionally identified novel risk factors of them. The nomogram may serve as a practical tool for the prognostic estimation and rapid decision of therapeutic strategies for patients with OA-EMZL. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Shi, J., Zhu, T., Zhou, M., Zhou, X., Song, X., Wang, Y., Jia, R., Yu, Z., Zhou, Y., Fan, X. Tags: Original articles - Clinical science Source Type: research
Novel ophthalmic findings and deep phenotyping in Williams-Beuren syndrome
Conclusion
WBS is a complex multisystem genetic disorder with diverse ophthalmic findings that differ from those seen in isolated elastin mediated SVAS. These results suggest other genes within the WBS critical region, aside from ELN, may be involved in observed ocular phenotypes and perhaps broader ocular development. Furthermore, retinal arteriolar tortuosity may provide future insight into systemic vascular findings in WBS. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Huryn, L. A., Flaherty, T., Nolen, R., Prasov, L., Zein, W. M., Cukras, C. A., Osgood, S., Raja, N., Levin, M. D., Vitale, S., Brooks, B. P., Hufnagel, R. B., Kozel, B. A. Tags: Open access Original articles - Clinical science Source Type: research
Genetic and clinical landscape of ARR3-associated MYP26: the most common cause of Mendelian early-onset high myopia with a unique inheritance
Conclusion
This study reveals ARR3 as the most frequently implicated gene for Mendelian eoHM. Truncations and highly scored missense variants in ARR3 are pathogenic. Myopia due to ARR3 mutations is transmitted in X-linked female-limited inheritance, manifests with mild cone impairment and slowly progresses to pathologic myopia. Identification of the most common cause for Mendelian eoHM provides a valuable starting point into the molecular mechanism of myopia. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Wang, Y., Xiao, X., Li, X., Yi, Z., Jiang, Y., Zhang, F., Zhou, L., Li, S., Jia, X., Sun, W., Wang, P., Zhang, Q. Tags: Open access Original articles - Clinical science Source Type: research
Oral administration of caffeine metabolite 7-methylxanthine is associated with slowed myopia progression in Danish children
Conclusions
Oral intake of 7-MX was associated with reduced myopia progression and reduced axial elongation in this sample of myopic children from Denmark. Randomised controlled trials are needed to determine whether the association is causal. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Trier, K., Cui, D., Ribel-Madsen, S., Guggenheim, J. Tags: Press releases Original articles - Clinical science Source Type: research
Role of corneal radius of curvature in early identification of fundus tessellation in children with low myopia
Conclusion
Fundus tessellation existed in more than half of children with low myopia. Preliminary fundus photography conducted in children with low myopia with large CR would be necessary and beneficial to the early management of myopic fundus changes.
Trial registration number NCT02980445. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Gong, W., Cheng, T., Wang, J., Zhang, B., Chen, J., Zhu, J., Zou, H., Liu, K., He, X., Xu, X. Tags: Open access Original articles - Clinical science Source Type: research
Comparison of biometric and refractive changes in intermittent exotropia with and without overminus lens therapy
Conclusion
No significant differences in biometry or refraction were found between the two groups and before and after the therapy. We conclude that the overminus therapy in children, not accounting for other myopia risk factors, does not affect normal refractive growths. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Ale Magar, J. B., Shah, S. P., Dai, S. Tags: Original articles - Clinical science Source Type: research
Nalbuphine as analgesic in preschool children undergoing ophthalmic surgery and the occurrence of emergence delirium
Conclusion
Nalbuphine shows a sufficient analgesic effect for pain therapy following ophthalmic surgery in preschool children. Nalbuphine seems to reduce the incidence of EDA in children undergoing ophthalmic surgery. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Leister, N., Trieschmann, U., Yücetepe, S., Ulrichs, C., Muenke, N., Wendt, S., Menzel, C., Heindl, L. M. Tags: Original articles - Clinical science Source Type: research
Deep learning model to identify homonymous defects on automated perimetry
Conclusion
This newly developed deep learning model achieved an overall average accuracy of 87%, making it highly effective in identifying homonymous VF defects on automated perimetry. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Tan, A. H., Donaldson, L., Moolla, L., Pereira, A., Margolin, E. Tags: Original articles - Clinical science Source Type: research
Incidence, progression and regression of diabetic retinopathy in a northeastern Chinese population
Conclusion
We determined the incidence, progression and regression of DR among northeastern Chinese patients with type 2 diabetes. Retinal vessel diameters, in addition to blood glucose level, influence the natural evolution of DR. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Lin, Z., Wen, L., Wang, Y., Li, D., Zhai, G., Moonasar, N., Wang, F., Liang, Y. Tags: Editor's choice Original articles - Clinical science Source Type: research
