Communicative impairment and its neural correlates in Alzheimer's disease and frontotemporal dementia
ConclusionsOur study demonstrates that communication barriers and resources can be successfully assessed via a structured interview based on self-report and report of patients ’ relatives in practice and are reflected in neuroimaging specific for AD and FTD as well as in further clinical parameters specific for these neurodegenerative diseases. This can potentially open new treatment options for clinical practice and patient care. (Source: Brain and Behavior)
Source: Brain and Behavior - March 18, 2024 Category: Neurology Authors: Alexa Haeger, Janka Muising, Sandro Romanzetti, Bruno Fimm, Oliver Matz, J örg B. Schulz, Stefan Heim, Kathrin Reetz Tags: ORIGINAL ARTICLE Source Type: research

Rapid eye movement sleep behavior disorder and its relation to Parkinson's disease: The potential of graph measures as brain biomarkers to identify the underlying physiopathology of the disorder
AbstractRapid eye movement behavior disorder (RBD) is a parasomnia characterized by the loss of skeletal muscle atonia during the rapid eye movement (REM) sleep phase. On the other hand, idiopathic RDB (iRBD) is considered the prelude of the various α-synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies and multiple system atrophy. Consequently, over 40% of patients eventually develop PD. Recent neuroimaging studies utilizing structural magnetic resonance imaging (s-MRI), diffusion-weighted imaging (DWI), and functi onal magnetic resonance imaging (fMRI) with graph theoretical analysis have dem...
Source: Brain and Behavior - March 18, 2024 Category: Neurology Authors: Milad Najafzadeh, Fatemeh Mohammadian, Sara Mirabian, Zohre Ganji, Hossein Akbari, Masoud Rezaie, Esmaeil Ranjbar, Hoda Zare, Shahrokh Nasseri, Luigi Ferini ‐Strambi Tags: REVIEW Source Type: research

Identifying and verifying Huntington's disease subtypes: Clinical features, neuroimaging, and cytokine changes
ConclusionWe have identified three HD clusters via clinical manifestations with distinct biomarkers. Our data shed light on better understanding about the pathophysiology of HD. (Source: Brain and Behavior)
Source: Brain and Behavior - March 18, 2024 Category: Neurology Authors: Ling ‐Xiao Cao, Jin‐Hui Yin, Gang Du, Qing Yang, Yue Huang Tags: ORIGINAL ARTICLE Source Type: research

Inhibition of leukocyte migration after ischemic stroke by VE ‐cadherin mutation in a mouse model leads to reduced infarct volumes and improved motor skills
ConclusionSelective inhibition of transendothelial leukocyte migration by VE-cadherin mutation after ischemic stroke in a mouse model leads to smaller infarct volumes and improved motor skills. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Mailin Hannah Marie Koecke, Jan ‐Kolja Strecker, Frederike Anne Straeten, Carolin Beuker, Jens Minnerup, Antje Schmidt‐Pogoda, Anna‐Lena Börsch Tags: ORIGINAL ARTICLE Source Type: research

Hippocampal resting ‐state connectivity is associated with posterior‐cortical cognitive impairment in Parkinson's disease
ConclusionResults suggest that weakened connectivity between the hippocampus and fusiform region is a unique characteristic of posterior-cortical cognitive deficits in PD. Further exploration of hippocampal and fusiform functional integrity as a marker of cognitive decline in PD is warranted. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Dana Pourzinal, Jihyun Yang, Katie L. McMahon, David A. Copland, Leander Mitchell, John D. O'Sullivan, Gerard J. Byrne, Nadeeka N. Dissanayaka Tags: ORIGINAL ARTICLE Source Type: research

Study of vision ‐related resting‐state activity in suprasellar tumor patients with postoperative visual damage
ConclusionsThe study results indicate significant neural reorganization in the vision-related cortex of ST patients with postoperative vision damage. Most subareas within the visual cortex showed remarkable neural dysfunction, and some highe-order cortex may be primarily involved in top-down control of the subareas within the visual cortex. The hot zones may arise in the processing of “top-down” influence. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Fuyu Wang, Tao Zhou, Peng Wang, Yanyang Zhang, Jinli Jiang Tags: ORIGINAL ARTICLE Source Type: research

Causal association between atopic dermatitis and Parkinson's disease: A bidirectional Mendelian randomization study
ConclusionThis study indicated causal association of genetically proxied atopic dermatitis with the risk of PD. Future studies are warranted to explore the underlying mechanism and investigate the targeting effect of atopic dermatitis on PD. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Taofeng Zhou, Baohao Wei, Yachun Hu, Xiaoming Zhou, Xiaoying Cai, Xiaolei Shi Tags: ORIGINAL ARTICLE Source Type: research

SP140 inhibitor suppressing TRIM22 expression regulates glioma progress through PI3K/AKT signaling pathway
ConclusionSP140-based nomogram proved to be a practical tool for predicting the survival of glioma patients. SP140 inhibitor could suppress glioma progress via TRIM22/PI3K/AKT signaling pathway. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Xiang Li, Guangzhao Li, Longyuan Li, Bixi Gao, Xiaowang Niu, Yunjiang Wang, Zhong Wang Tags: ORIGINAL ARTICLE Source Type: research

Sarcopenia and anti ‐seizure medication response in juvenile myoclonic epilepsy
ConclusionThe TMT did not differ between patients with JME and healthy controls; however, it was reduced in ASM poor responders compared to ASM good responders, suggesting a link between ASM response and sarcopenia in patients with JME. TMT can be used to investigate sarcopenia in various neurological disorders. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Jinseung Kim, Ho ‐Joon Lee, Dong Ah Lee, Kang Min Park Tags: ORIGINAL ARTICLE Source Type: research

The association between lymphocyte to high ‐density lipoprotein ratio and depression: Data from NHANES 2015–2018
ConclusionsA higher level of LHR was significantly associated with higher odds of having depression in US adults, and it was strengthened in participants with MetS or BMI ranging from 25 to 30  kg/m2. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Junzhi Chen, Yan Huang, Xiaolin Li Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of fibromyalgia and irritable bowel syndrome and its association with studying medicine, a cross ‐sectional study in Al‐Baath University, Syria
ConclusionWe found an increased prevalence of IBS among medical students. The prevalence of FM did not show any relation to studying medicine. We recommend additional prospective studies to assess whether studying medicine could be a risk factor for these disorders or not. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Mohanad Daher, Sara Abbas, Zainab Asaad, Karam Khalil, Ghania Jadid Tags: ORIGINAL ARTICLE Source Type: research

Factors associated with age of presentation of pediatric feeding disorder
ConclusionsInfants under 1 year old with PFD represent a distinct patient group with unique characteristics and outcomes. The age of presentation plays a significant role in children with PFD, necessitating tailored treatment strategies. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Tut Galai, Gal Friedman, Nataly Kalmintzky, Kim Shemer, Dana L Gal, Shlomi Cohen, Hadar Moran ‐Lev Tags: ORIGINAL ARTICLE Source Type: research

A retrospective, naturalistic study of deep brain stimulation and vagal nerve stimulation in young patients
ConclusionYoung patients may have distinct vulnerabilities for increased psychiatric symptoms during treatment with invasive neuromodulation. Child and adolescent psychiatrists should consider a more proactive approach and greater engagement with DBS and VNS teams that treat younger patients. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Deniz Yuruk, Can Ozger, Juan F. Garzon, Paul A. Nakonezny, Jennifer L. Vande Voort, Paul E. Croarkin Tags: ORIGINAL ARTICLE Source Type: research

Time is ticking for TikTok tics: A retrospective follow ‐up study in the post‐COVID‐19 isolation era
ConclusionWhile many patients ’ FTLBs improved, it is critical to remain alert to patients’ overall function and to assess for other functional neurological disorders and mental health concerns. The tendency of FTLBs to improve in this population, independent of treatment, highlights the unique pathophysiology of FTLBs. Futu re research on contributing psychosocial factors and specific treatment protocols will allow optimal support for these patients. (Source: Brain and Behavior)
Source: Brain and Behavior - March 12, 2024 Category: Neurology Authors: Kinga K. Tomczak, Jennifer Worhach, Michael Rich, Olivia Swearingen Ludolph, Susan Eppling, Georgios Sideridis, Tamar C. Katz Tags: ORIGINAL ARTICLE Source Type: research

Pre ‐saccadic shifts of attention in individuals diagnosed with schizophrenia
ConclusionThese findings suggest generally intact pre-saccadic shifts of attention in SZ, albeit slightly delayed. Results contribute to our understanding of altered sensory predictions in people with schizophrenia. (Source: Brain and Behavior)
Source: Brain and Behavior - March 7, 2024 Category: Neurology Authors: Matthew Lehet, Martin Rolfs, Jacqueline Bao, Jessica Fattal, Katharine N. Thakkar Tags: ORIGINAL ARTICLE Source Type: research