Neutralizing anti-diphtheria toxin scFv produced by phage display
CONCLUSION: This study describes the prosperous construction and isolation of scFv from the immune library, which specifically neutralizes diphtheria toxin. The HuscFv produced in this study can be a potential candidate to substitute the animal antibody for treating diphtheria and detecting toxins.PMID:38607601 | DOI:10.1007/s10529-024-03476-1 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Ehsan Khalili Mostafa Lakzaei Mahdi Aminian Source Type: research
Epigenetic modifiers as inducer of bioactive secondary metabolites in fungi
This study delves into the possibility of utilizing epigenetic modifying agents to generate pharmacologically significant secondary metabolites from fungi.PMID:38607602 | DOI:10.1007/s10529-024-03478-z (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Vishal Sharma Shivali Panjgotra Nisha Sharma Vidushi Abrol Umesh Goutam Sundeep Jaglan Source Type: research
Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium
CONCLUSION: An economically-feasible process for B. subtilis-based biocontrol agent production was successfully developed at the pilot scale.PMID:38607603 | DOI:10.1007/s10529-024-03481-4 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Emils Bolmanis Oskars Grigs Elina Didrihsone Maris Senkovs Vizma Nikolajeva Source Type: research
A cellulosomal yeast reaction system of lignin-degrading enzymes for cellulosic ethanol fermentation
In this study, a composite functional chimeric cellulosome equipped with laccase, versatile peroxidase, and lytic polysaccharide monooxygenase was riveted on the surface of Saccharomyces cerevisiae to construct a novel yeast strain YI/LVP for synergistic lignin degradation and cellulosic ethanol production. The assembly of cellulosome was assayed by immunofluorescence microscopy and flow cytometry. During the whole process of fermentation, the maximum ethanol concentration and cellulose conversion of engineering strain YI/LVP reached 8.68 g/L and 83.41%, respectively. The results proved the availability of artificial chime...
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Yutong Ye Han Liu Zhipeng Wang Qi Qi Jiliang Du Shen Tian Source Type: research
Neutralizing anti-diphtheria toxin scFv produced by phage display
CONCLUSION: This study describes the prosperous construction and isolation of scFv from the immune library, which specifically neutralizes diphtheria toxin. The HuscFv produced in this study can be a potential candidate to substitute the animal antibody for treating diphtheria and detecting toxins.PMID:38607601 | DOI:10.1007/s10529-024-03476-1 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Ehsan Khalili Mostafa Lakzaei Mahdi Aminian Source Type: research
Epigenetic modifiers as inducer of bioactive secondary metabolites in fungi
This study delves into the possibility of utilizing epigenetic modifying agents to generate pharmacologically significant secondary metabolites from fungi.PMID:38607602 | DOI:10.1007/s10529-024-03478-z (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Vishal Sharma Shivali Panjgotra Nisha Sharma Vidushi Abrol Umesh Goutam Sundeep Jaglan Source Type: research
Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium
CONCLUSION: An economically-feasible process for B. subtilis-based biocontrol agent production was successfully developed at the pilot scale.PMID:38607603 | DOI:10.1007/s10529-024-03481-4 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Emils Bolmanis Oskars Grigs Elina Didrihsone Maris Senkovs Vizma Nikolajeva Source Type: research
A cellulosomal yeast reaction system of lignin-degrading enzymes for cellulosic ethanol fermentation
In this study, a composite functional chimeric cellulosome equipped with laccase, versatile peroxidase, and lytic polysaccharide monooxygenase was riveted on the surface of Saccharomyces cerevisiae to construct a novel yeast strain YI/LVP for synergistic lignin degradation and cellulosic ethanol production. The assembly of cellulosome was assayed by immunofluorescence microscopy and flow cytometry. During the whole process of fermentation, the maximum ethanol concentration and cellulose conversion of engineering strain YI/LVP reached 8.68 g/L and 83.41%, respectively. The results proved the availability of artificial chime...
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Yutong Ye Han Liu Zhipeng Wang Qi Qi Jiliang Du Shen Tian Source Type: research
Neutralizing anti-diphtheria toxin scFv produced by phage display
CONCLUSION: This study describes the prosperous construction and isolation of scFv from the immune library, which specifically neutralizes diphtheria toxin. The HuscFv produced in this study can be a potential candidate to substitute the animal antibody for treating diphtheria and detecting toxins.PMID:38607601 | DOI:10.1007/s10529-024-03476-1 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Ehsan Khalili Mostafa Lakzaei Mahdi Aminian Source Type: research
Epigenetic modifiers as inducer of bioactive secondary metabolites in fungi
This study delves into the possibility of utilizing epigenetic modifying agents to generate pharmacologically significant secondary metabolites from fungi.PMID:38607602 | DOI:10.1007/s10529-024-03478-z (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Vishal Sharma Shivali Panjgotra Nisha Sharma Vidushi Abrol Umesh Goutam Sundeep Jaglan Source Type: research
Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium
CONCLUSION: An economically-feasible process for B. subtilis-based biocontrol agent production was successfully developed at the pilot scale.PMID:38607603 | DOI:10.1007/s10529-024-03481-4 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Emils Bolmanis Oskars Grigs Elina Didrihsone Maris Senkovs Vizma Nikolajeva Source Type: research
A cellulosomal yeast reaction system of lignin-degrading enzymes for cellulosic ethanol fermentation
In this study, a composite functional chimeric cellulosome equipped with laccase, versatile peroxidase, and lytic polysaccharide monooxygenase was riveted on the surface of Saccharomyces cerevisiae to construct a novel yeast strain YI/LVP for synergistic lignin degradation and cellulosic ethanol production. The assembly of cellulosome was assayed by immunofluorescence microscopy and flow cytometry. During the whole process of fermentation, the maximum ethanol concentration and cellulose conversion of engineering strain YI/LVP reached 8.68 g/L and 83.41%, respectively. The results proved the availability of artificial chime...
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Yutong Ye Han Liu Zhipeng Wang Qi Qi Jiliang Du Shen Tian Source Type: research
Improvement of cell growth in green algae Chlamydomonas reinhardtii through co-cultivation with yeast Saccharomyces cerevisiae
CONCLUSION: We successfully increased C. reinhardtii growth potential by co-culturing it with S. cerevisiae. The main reasons for this are likely to be an increase in inorganic nitrogen available to green algae via yeast metabolism and an increase in energy available for green algae growth instead of CO2 enrichment.PMID:38578514 | DOI:10.1007/s10529-024-03483-2 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 5, 2024 Category: Biotechnology Authors: Yukino Karitani Ryosuke Yamada Takuya Matsumoto Hiroyasu Ogino Source Type: research
Improvement of cell growth in green algae Chlamydomonas reinhardtii through co-cultivation with yeast Saccharomyces cerevisiae
CONCLUSION: We successfully increased C. reinhardtii growth potential by co-culturing it with S. cerevisiae. The main reasons for this are likely to be an increase in inorganic nitrogen available to green algae via yeast metabolism and an increase in energy available for green algae growth instead of CO2 enrichment.PMID:38578514 | DOI:10.1007/s10529-024-03483-2 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 5, 2024 Category: Biotechnology Authors: Yukino Karitani Ryosuke Yamada Takuya Matsumoto Hiroyasu Ogino Source Type: research
Improvement of cell growth in green algae Chlamydomonas reinhardtii through co-cultivation with yeast Saccharomyces cerevisiae
CONCLUSION: We successfully increased C. reinhardtii growth potential by co-culturing it with S. cerevisiae. The main reasons for this are likely to be an increase in inorganic nitrogen available to green algae via yeast metabolism and an increase in energy available for green algae growth instead of CO2 enrichment.PMID:38578514 | DOI:10.1007/s10529-024-03483-2 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 5, 2024 Category: Biotechnology Authors: Yukino Karitani Ryosuke Yamada Takuya Matsumoto Hiroyasu Ogino Source Type: research
