BRCA1 deficiency enhances the aggressiveness of breast cancer cells expressing HPV16 oncoproteins
CONCLUSIONS: Our results indicate that a deficiency of BRCA1 promotes the transactivation activity of HPV16E6E7 leading to increase of cell proliferation and invasion.SIGNIFICANCE: HPV infection appears to have the potential to enhance the aggressiveness of breast cancers, especially those deficient in BRCA1.PMID:38514439 | DOI:10.1111/boc.202300072 (Source: Biology of the Cell)
Source: Biology of the Cell - March 21, 2024 Category: Cytology Authors: Jariya Sangthong Chanitra Thuwajit Laran T Jensen Waraporn Komyod Jirundon Yuvaniyama Mathurose Ponglikitmongkol Source Type: research

BRCA1 deficiency enhances the aggressiveness of breast cancer cells expressing HPV16 oncoproteins
CONCLUSIONS: Our results indicate that a deficiency of BRCA1 promotes the transactivation activity of HPV16E6E7 leading to increase of cell proliferation and invasion.SIGNIFICANCE: HPV infection appears to have the potential to enhance the aggressiveness of breast cancers, especially those deficient in BRCA1.PMID:38514439 | DOI:10.1111/boc.202300072 (Source: Biology of the Cell)
Source: Biology of the Cell - March 21, 2024 Category: Cytology Authors: Jariya Sangthong Chanitra Thuwajit Laran T Jensen Waraporn Komyod Jirundon Yuvaniyama Mathurose Ponglikitmongkol Source Type: research

BRCA1 deficiency enhances the aggressiveness of breast cancer cells expressing HPV16 oncoproteins
CONCLUSIONS: Our results indicate that a deficiency of BRCA1 promotes the transactivation activity of HPV16E6E7 leading to increase of cell proliferation and invasion.SIGNIFICANCE: HPV infection appears to have the potential to enhance the aggressiveness of breast cancers, especially those deficient in BRCA1.PMID:38514439 | DOI:10.1111/boc.202300072 (Source: Biology of the Cell)
Source: Biology of the Cell - March 21, 2024 Category: Cytology Authors: Jariya Sangthong Chanitra Thuwajit Laran T Jensen Waraporn Komyod Jirundon Yuvaniyama Mathurose Ponglikitmongkol Source Type: research

BRCA1 deficiency enhances the aggressiveness of breast cancer cells expressing HPV16 oncoproteins
CONCLUSIONS: Our results indicate that a deficiency of BRCA1 promotes the transactivation activity of HPV16E6E7 leading to increase of cell proliferation and invasion.SIGNIFICANCE: HPV infection appears to have the potential to enhance the aggressiveness of breast cancers, especially those deficient in BRCA1.PMID:38514439 | DOI:10.1111/boc.202300072 (Source: Biology of the Cell)
Source: Biology of the Cell - March 21, 2024 Category: Cytology Authors: Jariya Sangthong Chanitra Thuwajit Laran T Jensen Waraporn Komyod Jirundon Yuvaniyama Mathurose Ponglikitmongkol Source Type: research

Editorial for the "Cell Energetics & amp; Cell Mechanics" themed issues
Biol Cell. 2024 Mar 17:e2400026. doi: 10.1111/boc.202400026. Online ahead of print.NO ABSTRACTPMID:38494422 | DOI:10.1111/boc.202400026 (Source: Biology of the Cell)
Source: Biology of the Cell - March 17, 2024 Category: Cytology Authors: Ren é Marc Mège Geri Kreitzer Source Type: research

Editorial for the "Cell Energetics & amp; Cell Mechanics" themed issues
Biol Cell. 2024 Mar 17:e2400026. doi: 10.1111/boc.202400026. Online ahead of print.NO ABSTRACTPMID:38494422 | DOI:10.1111/boc.202400026 (Source: Biology of the Cell)
Source: Biology of the Cell - March 17, 2024 Category: Cytology Authors: Ren é Marc Mège Geri Kreitzer Source Type: research

Editorial for the "Cell Energetics & amp; Cell Mechanics" themed issues
Biol Cell. 2024 Mar 17:e2400026. doi: 10.1111/boc.202400026. Online ahead of print.NO ABSTRACTPMID:38494422 | DOI:10.1111/boc.202400026 (Source: Biology of the Cell)
Source: Biology of the Cell - March 17, 2024 Category: Cytology Authors: Ren é Marc Mège Geri Kreitzer Source Type: research

Editorial for the "Cell Energetics & amp; Cell Mechanics" themed issues
Biol Cell. 2024 Mar 17:e2400026. doi: 10.1111/boc.202400026. Online ahead of print.NO ABSTRACTPMID:38494422 | DOI:10.1111/boc.202400026 (Source: Biology of the Cell)
Source: Biology of the Cell - March 17, 2024 Category: Cytology Authors: Ren é Marc Mège Geri Kreitzer Source Type: research

Testicular niche repair after gonadotoxic treatments: Current knowledge and future directions
Biol Cell. 2024 Mar 12:e2300123. doi: 10.1111/boc.202300123. Online ahead of print.ABSTRACTThe testicular niche, which includes the germ cells, somatic cells, and extracellular matrix, plays a crucial role in maintaining the proper functions of the testis. Gonadotoxic treatments, such as chemotherapy and radiation therapy, have significantly improved the survival rates of cancer patients but have also been shown to have adverse effects on the testicular microenvironment. Therefore, repairing the testicular niche after gonadotoxic treatments is essential to restore its function. In recent years, several approaches, such as ...
Source: Biology of the Cell - March 12, 2024 Category: Cytology Authors: Amirhossein Mohammadi Zahra Bashiri Sara Rafiei Hamidreza Asgari Ronak Shabani SeyedJamal Hosseini Morteza Koruji Source Type: research

Testicular niche repair after gonadotoxic treatments: Current knowledge and future directions
Biol Cell. 2024 Mar 12:e2300123. doi: 10.1111/boc.202300123. Online ahead of print.ABSTRACTThe testicular niche, which includes the germ cells, somatic cells, and extracellular matrix, plays a crucial role in maintaining the proper functions of the testis. Gonadotoxic treatments, such as chemotherapy and radiation therapy, have significantly improved the survival rates of cancer patients but have also been shown to have adverse effects on the testicular microenvironment. Therefore, repairing the testicular niche after gonadotoxic treatments is essential to restore its function. In recent years, several approaches, such as ...
Source: Biology of the Cell - March 12, 2024 Category: Cytology Authors: Amirhossein Mohammadi Zahra Bashiri Sara Rafiei Hamidreza Asgari Ronak Shabani SeyedJamal Hosseini Morteza Koruji Source Type: research

Testicular niche repair after gonadotoxic treatments: Current knowledge and future directions
Biol Cell. 2024 Mar 12:e2300123. doi: 10.1111/boc.202300123. Online ahead of print.ABSTRACTThe testicular niche, which includes the germ cells, somatic cells, and extracellular matrix, plays a crucial role in maintaining the proper functions of the testis. Gonadotoxic treatments, such as chemotherapy and radiation therapy, have significantly improved the survival rates of cancer patients but have also been shown to have adverse effects on the testicular microenvironment. Therefore, repairing the testicular niche after gonadotoxic treatments is essential to restore its function. In recent years, several approaches, such as ...
Source: Biology of the Cell - March 12, 2024 Category: Cytology Authors: Amirhossein Mohammadi Zahra Bashiri Sara Rafiei Hamidreza Asgari Ronak Shabani SeyedJamal Hosseini Morteza Koruji Source Type: research

Testicular niche repair after gonadotoxic treatments: Current knowledge and future directions
Biol Cell. 2024 Mar 12:e2300123. doi: 10.1111/boc.202300123. Online ahead of print.ABSTRACTThe testicular niche, which includes the germ cells, somatic cells, and extracellular matrix, plays a crucial role in maintaining the proper functions of the testis. Gonadotoxic treatments, such as chemotherapy and radiation therapy, have significantly improved the survival rates of cancer patients but have also been shown to have adverse effects on the testicular microenvironment. Therefore, repairing the testicular niche after gonadotoxic treatments is essential to restore its function. In recent years, several approaches, such as ...
Source: Biology of the Cell - March 12, 2024 Category: Cytology Authors: Amirhossein Mohammadi Zahra Bashiri Sara Rafiei Hamidreza Asgari Ronak Shabani SeyedJamal Hosseini Morteza Koruji Source Type: research

Testicular niche repair after gonadotoxic treatments: Current knowledge and future directions
Biol Cell. 2024 Mar 12:e2300123. doi: 10.1111/boc.202300123. Online ahead of print.ABSTRACTThe testicular niche, which includes the germ cells, somatic cells, and extracellular matrix, plays a crucial role in maintaining the proper functions of the testis. Gonadotoxic treatments, such as chemotherapy and radiation therapy, have significantly improved the survival rates of cancer patients but have also been shown to have adverse effects on the testicular microenvironment. Therefore, repairing the testicular niche after gonadotoxic treatments is essential to restore its function. In recent years, several approaches, such as ...
Source: Biology of the Cell - March 12, 2024 Category: Cytology Authors: Amirhossein Mohammadi Zahra Bashiri Sara Rafiei Hamidreza Asgari Ronak Shabani SeyedJamal Hosseini Morteza Koruji Source Type: research

Cells flowing to attain functionality
Biol Cell. 2024 Mar 5:e2300150. doi: 10.1111/boc.202300120. Online ahead of print.ABSTRACTUnraveling the fundamental biological processes underpinning cell functions and behavior remains a key challenge. Researchers working on cell biological processes might want to take a look at microscale cell flow as functionality genesis. This Commentary provides an outlook on how cell-microcirculation interplay promises to lead to exciting insights into the cell biology complexity.PMID:38444250 | DOI:10.1111/boc.202300120 (Source: Biology of the Cell)
Source: Biology of the Cell - March 6, 2024 Category: Cytology Authors: Mart ín G Bellino Source Type: research

Cells flowing to attain functionality
Biol Cell. 2024 Mar 5:e2300150. doi: 10.1111/boc.202300120. Online ahead of print.ABSTRACTUnraveling the fundamental biological processes underpinning cell functions and behavior remains a key challenge. Researchers working on cell biological processes might want to take a look at microscale cell flow as functionality genesis. This Commentary provides an outlook on how cell-microcirculation interplay promises to lead to exciting insights into the cell biology complexity.PMID:38444250 | DOI:10.1111/boc.202300120 (Source: Biology of the Cell)
Source: Biology of the Cell - March 6, 2024 Category: Cytology Authors: Mart ín G Bellino Source Type: research