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Using a Smartphone to Screen for Male Infertility
Easy-to-use smartphone app and accessory analyzes sperm concentration and motility with ~98 percent accuracy. (Source: BWH for Journalists)
Source: BWH for Journalists - March 22, 2017 Category: Research Source Type: news

PCSK9 Inhibitor Evolocumab Significantly Reduces Adverse Cardiovascular Events When Added to Statin Therapy With No Major Safety Concerns
In patients with cardiovascular disease, evolocumab reduced LDL cholesterol by 59 percent and reduced the risk of adverse cardiovascular outcomes with greater benefit the longer the duration of therapy. (Source: BWH for Journalists)
Source: BWH for Journalists - March 17, 2017 Category: Research Source Type: news

58 Million Americans are Exposed to Loud, Frequent Noises, Including Firearms, at Work and Home
Study finds substantial noise exposures, with potentially serious long-term hearing health consequences, frequently occur in occupational and recreational settings (Source: BWH for Journalists)
Source: BWH for Journalists - March 16, 2017 Category: Research Source Type: news

58 Million Americans are Exposed to Loud, Frequent Noises,
Study finds substantial noise exposures, with potentially serious long-term hearing health consequences, (Source: BWH for Journalists)
Source: BWH for Journalists - March 16, 2017 Category: Research Source Type: news

Study details risks of death following ischemic or bleeding events more than one year after coronary stenting
A study by a multi-institutional research team has tracked the long-term incidence of death following ischemic and bleeding events occurring in patients more than one year after placement of a coronary stent. (Source: BWH for Journalists)
Source: BWH for Journalists - March 15, 2017 Category: Research Source Type: news

Putting Autoimmune Disease Genetic Links to the Test
Investigators took approximately 270 genetic loci associated with seven diseases and tried to map them back to causal genes using eQTLs in key immune cells. (Source: BWH for Journalists)
Source: BWH for Journalists - March 15, 2017 Category: Research Source Type: news

A Breath of Fresh Air for Severe Asthma Research
In-depth study of severe asthma yields new insights into the immunology of the disease with important clinical implications. (Source: BWH for Journalists)
Source: BWH for Journalists - March 13, 2017 Category: Research Source Type: news

Study highlights possible Achilles ’ heel in key immune memory cells
Genes involved in lipid metabolism are highly active in TRM cells, roughly 20- to 30-fold more active than in other types of T-cells (Source: BWH for Journalists)
Source: BWH for Journalists - March 9, 2017 Category: Research Source Type: news

Exploring a New Complication from an Emergent Tickborne Parasite
Investigating cases of warm-antibody autoimmune hemolytic anemia (WAHA) in patients after treatments for babesiosis (Source: BWH for Journalists)
Source: BWH for Journalists - March 9, 2017 Category: Research Source Type: news

New Technology Platform Propels the Use of “Organs-On-Chips”
A research team led by BWH has developed a novel technology platform that enables the continuous and automated monitoring of so-called “organs-on-chips”. (Source: BWH for Journalists)
Source: BWH for Journalists - March 7, 2017 Category: Research Source Type: news

Skin testing, computerized support tool can improve antibiotic use in hospital inpatients
Confirming whether or not a recorded penicillin allergy is real could reduce negative effects of alternate antibiotics (Source: BWH for Journalists)
Source: BWH for Journalists - March 6, 2017 Category: Research Source Type: news

Organ-on-a-Chip Model Offers Insights into Premature Aging and Vascular Disease
Progeria-on-a-chip model recapitulates blood vessel dynamics to better understand vascular disease and aging. (Source: BWH for Journalists)
Source: BWH for Journalists - March 3, 2017 Category: Research Source Type: news

Scientists Unlock Ability to Generate New Sensory Hair Cells
Scientists describe a technique to grow large quantities of inner ear progenitor cells that convert into hair cells. (Source: BWH for Journalists)
Source: BWH for Journalists - February 21, 2017 Category: Research Source Type: news

Clues in tumor genomes help predict patients ’ response to immunotherapy
Rsearchers have uncovered a surprising connection between the abnormalities in the number of chromosomes within a tumor& the tumor ’s response to a key class of cancer drugs, known as immune checkpoint inhibitors. (Source: BWH for Journalists)
Source: BWH for Journalists - February 16, 2017 Category: Research Source Type: news

Making the Stand-Ins Stand Out In Cancer
Team from Brigham and Women ’s Hospital uses systematic approach to reveal how cancer driver genes can substitute for each other and promote therapeutic resistance (Source: BWH for Journalists)
Source: BWH for Journalists - February 16, 2017 Category: Research Source Type: news

Study sheds light on the biology of progressive form of multiple sclerosis, suggests a new potential path for treatment
A research team led by scientists from Brigham and Women ’s Hospital (BWH) has revealed how an FDA-approved drug works in the central nervous system in mice to suppress chronic inflammation. (Source: BWH for Journalists)
Source: BWH for Journalists - February 8, 2017 Category: Research Source Type: news

Novel Tool Informs Women About Elective Egg Freezing
Personalized predictive model offers data-driven guidance for women deciding how many eggs to freeze (Source: BWH for Journalists)
Source: BWH for Journalists - February 6, 2017 Category: Research Source Type: news

Stomach Acid Provides Long-Term Power For Ingestible Devices
Researchers develop ingestible prototypes that draw energy from gastric acid, provide power that lasts nearly a week (Source: BWH for Journalists)
Source: BWH for Journalists - February 6, 2017 Category: Research Source Type: news

Preterm Delivery Linked to Greater Risk of Cardiovascular Disease Later in Life
Compared to full-term births, women who delivered prematurely were at a significantly increased risk of developing cardiovascular disease (Source: BWH for Journalists)
Source: BWH for Journalists - February 2, 2017 Category: Research Source Type: news

Discovery of New T-Cell Subtype Opens Window on Rheumatoid Arthritis
Finding flows from researchers ’ use of high-tech tools to deeply and efficiently characterize patient cells (Source: BWH for Journalists)
Source: BWH for Journalists - February 1, 2017 Category: Research Source Type: news

10,000 Medicare Patients Die In The Seven Days After Discharge From The ED
Heart Attacks Found To Be Most Common Cause (Source: BWH for Journalists)
Source: BWH for Journalists - February 1, 2017 Category: Research Source Type: news

New Research Maps Hallmark of Parkinson ’s Disease to Genetic Risk Factors
Findings bring researchers one-step closer to personalized medicine for Parkinson ’s patients. (Source: BWH for Journalists)
Source: BWH for Journalists - January 26, 2017 Category: Research Source Type: news

Serum MicoRNAs May Serve as Biomarkers for Multiple Sclerosis
Researchers have found that serum microRNAs are linked to MRI findings in the brain and spinal cord in patients with MS. (Source: BWH for Journalists)
Source: BWH for Journalists - January 23, 2017 Category: Research Source Type: news

New Genomic Tool for Salamander Biology Could Spur Deeper Understanding of Tissue Regeneration
Researchers have created a catalogue of every active gene in a variety of tissues in the axolotl, a type of salamander known for its striking ability to fully regenerate limbs following amputation. (Source: BWH for Journalists)
Source: BWH for Journalists - January 17, 2017 Category: Research Source Type: news

Researchers Demonstrate Gene-Editing Technique That Blocks Glioblastoma Growth
Using the CRISPR-Cas9 gene editing system, researchers found that virus-mediated miR-10b gene ablation is a prom (Source: BWH for Journalists)
Source: BWH for Journalists - January 5, 2017 Category: Research Source Type: news

Nanoparticle-based method shows promise in DNA vaccine delivery
Scientists at Brigham and Women ’s Hospital have developed a novel method for delivering therapeutic molecules into cells. (Source: BWH for Journalists)
Source: BWH for Journalists - December 19, 2016 Category: Research Source Type: news

Longer Use of Pain Relievers Associated With Hearing Loss in Women
Women who used ibuprofen or acetaminophen for six years or more were at higher risk of hearing loss than those who used these medications for a year or less. (Source: BWH for Journalists)
Source: BWH for Journalists - December 15, 2016 Category: Research Source Type: news

Longer Use of Pain Relievers Associated With Hearing Loss in Women
Women who used ibuprofen or acetaminophen for six years or more were at higher risk of hearing loss than those who used these medications for a year or less (Source: BWH for Journalists)
Source: BWH for Journalists - December 9, 2016 Category: Research Source Type: news

Stephen J. Elledge, PhD, Wins Breakthrough Prize 2017
Award recognizes scientist ’s trail-blazing work on how cells sense DNA damage and initiate self-repair (Source: BWH for Journalists)
Source: BWH for Journalists - December 5, 2016 Category: Research Source Type: news

Ultra-Long Acting Pill Offers New Hope in Eliminating Malaria
BWH investigators and collaborators have created a swallowable capsule that can stay in the stomach and deliver medicine for up to two weeks or more. (Source: BWH for Journalists)
Source: BWH for Journalists - November 17, 2016 Category: Research Source Type: news

Molecular Signature for Aggressive Brain Tumor Uncovered
New findings suggest that a routine test can be used to identify which patients may require intensive clinical management and surveillance. (Source: BWH for Journalists)
Source: BWH for Journalists - November 10, 2016 Category: Research Source Type: news

Elucidating Sex differences in Alzheimer ’s Disease Risk
Study of memory function in early midlife period pinpoints changes linked with menopause (Source: BWH for Journalists)
Source: BWH for Journalists - November 9, 2016 Category: Research Source Type: news

Will Unanticipated Genetic Mutations Lead to Subsequent Disease?
New research suggests that persons carrying a genetic mutation in certain cancer and cardiovascular conditions are at greater risk for those conditions regardless of family history (Source: BWH for Journalists)
Source: BWH for Journalists - November 9, 2016 Category: Research Source Type: news

Activation of Two Genes Linked to Development of Atherosclerosis
two new potential drug targets for treating arterial diseases such as atherosclerosis identified (Source: BWH for Journalists)
Source: BWH for Journalists - October 28, 2016 Category: Research Source Type: news

Brigham and Women ’s Hospital Invests $4.45 Million Over Seven Years to Support Community-led Health Equity Efforts
This will be the beginning of a seven year hospital investment of $4.45 million to support community-led health equity efforts taking place in its five priority neighborhoods: Dorchester, Jamaica Plain, Mattapan, Mission Hill& Roxbury (Source: BWH for Journalists)
Source: BWH for Journalists - October 27, 2016 Category: Research Source Type: news

International Team Led by Calum MacRae Selected for One Brave Idea Research Award to Fight Coronary Heart Disease
$75 million research award will fund a joint initiative to define the earliest mechanisms of coronary heart disease (Source: BWH for Journalists)
Source: BWH for Journalists - October 5, 2016 Category: Research Source Type: news

Brigham and Women ’s Hospital Celebrates the Opening of the Building for Transformative Medicine
The new building accelerates the translation of science into the clinical setting (Source: BWH for Journalists)
Source: BWH for Journalists - September 29, 2016 Category: Research Source Type: news

Changes in Memory Tied to Menopausal Status
Memory changes may occur in women decades earlier than traditional aging studies take into account. (Source: BWH for Journalists)
Source: BWH for Journalists - September 27, 2016 Category: Research Source Type: news

First multicellular organism inspires the design of better cancer drugs
Inspired by Volvox, the first multicellular organism, researchers from Brigham and Women ’s Hospital have developed a novel approach for treating cancer (Source: BWH for Journalists)
Source: BWH for Journalists - September 12, 2016 Category: Research Source Type: news

New Insights Into Tumor-Infiltrating T Cells Opens Up New Avenues for Targeted Therapeutics
Gene module for T cell dysfunction identified (Source: BWH for Journalists)
Source: BWH for Journalists - September 8, 2016 Category: Research Source Type: news

PSA Failure Predicts Risk of Death Only In Healthy Men
Rise in prostate-specific antigen levels in healthy men significantly associated with increased risk of death (Source: BWH for Journalists)
Source: BWH for Journalists - September 6, 2016 Category: Research Source Type: news

Radiologists Detect Breast Cancer in “Blink of an Eye”
Study investigates how trained radiologists are able to distinguish normal from abnormal mammograms when shown images for only half a second. (Source: BWH for Journalists)
Source: BWH for Journalists - August 29, 2016 Category: Research Source Type: news

New Class of Molecules Play Key Role in Influencing the Immune System
Resolvins and maresins, molecules produced in the body naturally from certain omega-3 fatty acids, regulate subsets of white blood cells that play a central role in inflammation and the immune system (Source: BWH for Journalists)
Source: BWH for Journalists - August 24, 2016 Category: Research Source Type: news

Stubborn inequities in heart health persist for some African Americans in the South
Data from Jackson Heart Study reveals that healthy metrics are related to lower risk of heart attack or stroke among African Americans (Source: BWH for Journalists)
Source: BWH for Journalists - August 15, 2016 Category: Research Source Type: news

Omega-3 Fatty Acids May Promote Recovery After Heart Attack
Researchers from Brigham and Women ’s Hospital have found that omega-3 fatty acids from fish oil, in addition to current standard treatments, may help patients who recently suffered a heart attack recover. (Source: BWH for Journalists)
Source: BWH for Journalists - August 1, 2016 Category: Research Source Type: news

Patients with Non-Functional Adrenal Tumors at Increased Risk of Diabetes
Investigators from Brigham and Women ’s Hospital have found that “non-functional” adrenal tumors can increase a person’s risk of developing type 2 diabetes. (Source: BWH for Journalists)
Source: BWH for Journalists - August 1, 2016 Category: Research Source Type: news

Breastfeeding First 28 Days of Life for Pre-Term Babies Associated with Better Brain Development and Neurocognitive Outcomes
New research finds pre-term babies fed more breast milk in the first 28 days of life had larger deep nuclear gray matter volume and better IQs, academic achievements, memory, and motor function by age seven (Source: BWH for Journalists)
Source: BWH for Journalists - July 29, 2016 Category: Research Source Type: news

Tissue Glue Bioengineered at Brigham and Women ’s Hospital Successfully Used to Treat a Bulldog Suffering from Nasal Cavity Defect
A tissue adhesive was used to treat MSPCA-Angell patient “Little” Papi, a bulldog who had endured several unsuccessful treatments for his condition, oronasal fistula. (Source: BWH for Journalists)
Source: BWH for Journalists - July 27, 2016 Category: Research Source Type: news

Frequent Nut Consumption Associated with Less Inflammation
Five or more servings of nuts per week or substituting nuts for animal proteins tied to a healthy profile of inflammatory biomarkers. (Source: BWH for Journalists)
Source: BWH for Journalists - July 27, 2016 Category: Research Source Type: news

Giles Boland, MD, FACR Named Chair of the Department of Radiology at Brigham and Women ’s Health Care
New Chair of Radiology at BWHC (Source: BWH for Journalists)
Source: BWH for Journalists - July 25, 2016 Category: Research Source Type: news