Carotid Plaque Burden in Patient who Underwent Coronary Angiogram at Dhulikhel Hospital
Conclusion This study establishes a relationship between coronary artery disease and carotid plaque, suggesting that the presence of carotid plaque may serve as an indicator of underlying coronary artery disease.PMID:38628010 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: S Humagain S R Pathak R P Koju Source Type: research
Study of active components and mechanisms mediating the hypolipidemic effect of < em > Inonotus obliquus < /em > polysaccharides
Food Sci Nutr. 2024 Feb 6;12(4):2833-2845. doi: 10.1002/fsn3.3964. eCollection 2024 Apr.ABSTRACTHyperlipidemia is a multifaceted metabolic disease, which is the major risk factor for atherosclerosis and cardiovascular diseases. Traditional Chinese medicine provides valuable therapeutic strategies in the treatment of hyperlipidemia. Inonotus obliquus has been used in traditional medicine to treat numerous diseases for a long time. To screen and isolate the fractions of I. obliquus polysaccharides (IOP) that can reduce blood lipid in the hyperlipemia animals and cell models, and investigate its mechanisms. The active compone...
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Guanwen Ding Xiao Guo Xiao Li Liping An Huawen Shi Source Type: research
Positive orientation and health behaviors in older patients with atherosclerosis
CONCLUSIONS: There is a positive relationship between positive orientation and health behaviors. Positive orientation can be enhanced through appropriate psychoeducation and psychological support to prevent ill health and improve treatment of patients with atherosclerosis.PMID:38628275 | PMC:PMC11016943 | DOI:10.5114/hpr/163536 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Krzysztof K Suppan Ma łgorzata Basińska Aleksandra B łachnio Source Type: research
Internuclear ophthalmoplegia following radial artery cardiac catheterization approach: An unusual presentation
We report a rare case in a 47-year-old man presenting with diplopia after radial artery angioplasty. Although the symptoms were resolved after 60 days, diagnosing this obstacle is necessary to reduce the patient and physician's anxiety.PMID:38628413 | PMC:PMC11017003 | DOI:10.4103/sjopt.sjopt_2_23 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Seyed H Daryabari Seyed A Mosavi Seyed H Sharoubandi Hooman Zarei Source Type: research
A bibliometric analysis of the 100 most-cited clinical articles in the research of intracranial artery stenosis and intracranial atherosclerosis
CONCLUSION: The findings of this study provide novel insight into this field and will facilitate future research endeavors.PMID:38628533 | PMC:PMC11021113 | DOI:10.25259/SNI_1030_2023 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Yudai Hirano Satoru Miyawaki Yusuke Sakaguchi Satoshi Koizumi Hiroki Hongo Nobuhito Saito Source Type: research
Detection of common pathogenesis of rheumatoid arthritis and atherosclerosis via microarray data analysis
This study underscores the shared pathogenic mechanisms, pivotal genes, and potential therapeutic interventions bridging RA and AS, offering valuable insights for future research and clinical management strategies.PMID:38628735 | PMC:PMC11019104 | DOI:10.1016/j.heliyon.2024.e28029 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Fan Xu Linfeng Xie Jian He Qiuyu Huang Yanming Shen Liangwan Chen Xiaohong Zeng Source Type: research
Preclinical models of atherosclerosis: An overview
Iran J Basic Med Sci. 2024;27(5):535-542. doi: 10.22038/IJBMS.2024.74352.16148.ABSTRACTAtherosclerosis is a primary cause of illness and death globally and its mechanism is still unclear. Different animal models have been created to evaluate the progression of atherosclerosis, allowing researchers to carefully control the circumstances of the experiment as well as the nutrition and environmental risk factors. To investigate the negative effects of various interventions, pathophysiological alterations might be generated utilizing genetic or pharmacological methods. These models' molecular and pathophysiological mechanisms h...
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Priyanka Arya Vikram Sharma Surabhi Thapliyal Rahul Sagar Priyanka Singh Source Type: research
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: When considered collectively, statin therapy's advantages appear to exceed its occasional predictable side effects like liver or muscle toxicity.REGISTRATION: PROSPERO registration ID: CRD42023469521.PMID:38629133 | DOI:10.1080/17512433.2024.2344672 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Sai Santhosha Mrudula Alla Dhruv J Shah Vysakh Ratheesh Deekshitha Alla Thanmayee Tummala Moksh S Khetan Ritika J Shah Ruth G Bayeh Mahek Fatima Sanah K Ahmed Mert Sab ıroğlu Source Type: research
Orphan Nuclear Receptor NR4A3 Promotes Vascular Calcification via Histone Lactylation
CONCLUSIONS: Taken together, our findings reveal that NR4A3-mediated histone lactylation is a novel metabolome-epigenome signaling cascade mechanism that participates in the pathogenesis of medial arterial calcification.PMID:38629274 | DOI:10.1161/CIRCRESAHA.123.323699 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Wenqi Ma Kangni Jia Haomai Cheng Hong Xu Zhigang Li Hang Zhang Hongyang Xie Lingfang Zhuang Ziyang Wang Yuke Cui Hang Sun Lei Yi Zhiyong Chen Shengzhong Duan Motoaki Sano Keiichi Fukuda Lin Lu Fei Gao Ruiyan Zhang Xiaoxiang Yan Source Type: research
Extract of Gualou-Xiebai Herb Pair Improves Lipid Metabolism Disorders by Enhancing the Reverse Cholesterol Transport in Atherosclerosis Mice
CONCLUSION: In summary, our results suggested that GXE improved lipid metabolism disorders by enhancing RCT, providing a scientific basis for the clinical use of GXE in AS treatment.PMID:38629368 | DOI:10.2174/0115672026308438240405055719 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Yarong Liu Tian Wang Lidan Ding Zhenglong Li Yexiang Zhang Min Dai Hongfei Wu Source Type: research
Assessment of atherosclerotic plaque burden: comparison of AI-QCT versus SIS, CAC, visual and CAD-RADS stenosis categories
This study assesses the agreement of Artificial Intelligence-Quantitative Computed Tomography (AI-QCT) with qualitative approaches to atherosclerotic disease burden codified in the multisociety 2022 CAD-RADS 2.0 Expert Consensus. 105 patients who underwent cardiac computed tomography angiography (CCTA) for chest pain were evaluated by a blinded core laboratory through FDA-cleared software (Cleerly, Denver, CO) that performs AI-QCT through artificial intelligence, analyzing factors such as % stenosis, plaque volume, and plaque composition. AI-QCT plaque volume was then staged by recently validated prognostic thresholds, and...
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Hufsa Khan Kopal Bansal William F Griffin Catherine Cantlay Alfateh Sidahmed Nick S Nurmohamed Robert K Zeman Richard J Katz Ron Blankstein James P Earls Andrew D Choi Source Type: research
Mast cells: a novel therapeutic avenue for cardiovascular diseases?
Cardiovasc Res. 2024 Apr 17:cvae066. doi: 10.1093/cvr/cvae066. Online ahead of print.ABSTRACTMast cells are tissue-resident immune cells strategically located in different compartments of the normal human heart (the myocardium, pericardium, aortic valve and close to nerves) as well as in atherosclerotic plaques. Cardiac mast cells produce a broad spectrum of vasoactive and proinflammatory mediators, which have potential roles in inflammation, angiogenesis, lymphangiogenesis, tissue remodeling and fibrosis. Mast cells release preformed mediators (e.g., histamine, tryptase, chymase) and de novo synthesized mediators [e.g., c...
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Remo Poto Gianni Marone Stephen J Galli Gilda Varricchi Source Type: research
Evaluation of the mechanism of Gong Ying San activity on dairy cows mastitis by network pharmacology and metabolomics analysis
CONCLUSIONS: An integrative investigation based on a bioinformatics-network topology provided new insights into the synergistic, multicomponent mechanisms of GYS's anti-inflammatory, antibacterial, and antioxidant activities. It revealed novel possibilities for developing new combination medications for reducing mastitis and its complications.PMID:38630770 | DOI:10.1371/journal.pone.0299234 (Source: Atherosclerosis)
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Shuang Gao Liyun Tang Jiayi Ma Kaiming Wang Hua Yao Jinjin Tong Hua Zhang Source Type: research
Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway
Biochim Biophys Acta Mol Basis Dis. 2024 Apr 15:167170. doi: 10.1016/j.bbadis.2024.167170. Online ahead of print.ABSTRACTIntimal hyperplasia (IH) is a common pathological feature of vascular proliferative diseases, such as atherosclerosis and restenosis after angioplasty. Urotensin II (UII) and its receptor (UTR) are widely expressed in cardiovascular tissues. However, it remains unclear whether the UII/UTR system is involved in IH. Right unilateral common carotid artery ligation was performed and maintained for 21 days to induce IH in UTR knockout (UTR-/-) and wild-type (WT) mice. Histological analysis revealed that compa...
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Panpan Wei Kangli Tian Haole Liu Kexin Li Naqash Alam Daxin Cheng Meng Li Xue He Jia Guo Rong Wang Weirong Wang Liang Bai Enqi Liu Baohui Xu Yankui Li Sihai Zhao Source Type: research
In vitro and in vivo exposure of endothelial cells to dibutyl phthalate promotes monocyte adhesion
Food Chem Toxicol. 2024 Apr 15:114663. doi: 10.1016/j.fct.2024.114663. Online ahead of print.ABSTRACTThe effect of endothelial cells' exposure to dibutyl phthalate (DBP) on monocyte adhesion is largely unknown. We evaluated monocyte adhesion to DBP-exposed endothelial cells by combining three approaches: short-term exposure (24 h) of EA.hy926 cells to 10-6, 10-5, and 10-4 M DBP, long-term exposure (12 weeks) of EA.hy926 cells to 10-9, 10-8, and 10-7 M DBP, and exposure of rats (28 and 90 days) to 100, 500, and 5000 mg DBP/kg food. Monocyte adhesion to human EA.hy926 and rat aortic endothelial cells, expression of selected ...
Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Dunja Kokai Jelena Markovic Filipovic Marija Opacic Ivana Ivelja Vojislav Banjac Bojana Stanic Nebojsa Andric Source Type: research
