Nintedanib and pirfenidone for idiopathic pulmonary fibrosis in King Abdulaziz Medical City, Riyadh: Real-life data
CONCLUSIONS: Pirfenidone and nintedanib are the available approved antifibrotic agents used for many years to treat IPF patients. Real-life data showed better tolerability than reported in the West, good compliance, and a manageable side effect profile in this group of elderly and severe IPF patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Mohammed Ayaz Khan Nahed Sherbini Sami Alyami Abdullah Al-Harbi Majed Al-Ghamdi Suliman Alrajhi Rajkumar Rajendram Hamdan Al-Jahdali Source Type: research

Application of single-port laparoscopic retrograde gastric mobilization during McKeown esophagectomy for esophageal cancer
CONCLUSIONS: The SLRM is a technically feasible and safe treatment for patients with esophageal cancer. It can be considered an alternative method for patients, especially for the ones with obesity and gastric distension. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Bo Liu Xu Li Min-Jie Yu Jin-Bao Xie Guo-Liang Liao Ming-Lian Qiu Source Type: research

Optimal positive airway pressure requirement and polysomnography indices of obstructive sleep apnea severity in the Saudi population
CONCLUSIONS: The optimal PAP requirement in the Saudi population is relatively high and directly correlated with OSA severity. Diagnostic polysomnography measurements of OSA severity predicted the optimal PAP requirement in this sample. Prospective validation is warranted. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Ahmad A Bamagoos Shahad A Alshaynawi Atheer S Gari Atheer M Badawi Mudhawi H Alhiniah Asma A Alshahrani Renad R Rajab Reem K Bahaj Faris Alhejaili Siraj O Wali Source Type: research

Increased airway resistance among exclusive waterpipe smokers detected using impulse oscillometry
CONCLUSIONS: Waterpipe smoking is associated with increased airway resistance assessed by IOS but not by spirometry in largely asymptomatic individuals from the community. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Hassan A Chami Nourhan Houjeij Maha Makki Lina Itani Hani Tamim Ahmad Al Mulla Bartolome Celli Salah Zeineldine Source Type: research

Measurement of the awareness of venous thromboembolism in the Saudi population
CONCLUSION: In Saudi Arabia, the public awareness of VTE is poor. To improve outcomes, public health initiatives must increase awareness, introduce preventive measures, encourage early diagnosis, and ensure compliance with treatment. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Ali Alaklabi Shouq Mohammed AlNujaim Sarah Mohammed Alghaihab Sadeem Ahmed AlDakhil Obeid Mohammed AlKethami Rajkumar Rajendram Source Type: research

General rehabilitation for the Post-COVID-19 condition: A narrative review
This study aims to describe the rehabilitation management of post-COVID-19 conditions. As the number of survivors seems to be increasing, it is expected that COVID-19 survivors will recover through a holistic approach by all physicians. Comprehensive rehabilitation for long COVID or COVID-19-related illnesses includes exercising, nutrition, education, managing voice, breathlessness, neurocognitive problems, mental health, feeding problems, and daily activities. Specific recommendations have already been published to support rehabilitation for survivors in every targeted organ. Supportive care, especially rehabilitation pro...
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Dian Marta Sari Laurentia Cindy Gani Wijaya Source Type: research

The implications of Vitamin E acetate in E-cigarette, or vaping, product use-associated lung injury
Brian Soto, Louis Costanzo, Anoop Puskoor, Nada Akkari, Patrick GeraghtyAnnals of Thoracic Medicine 2023 18(1):1-9 In the summer of 2019, a cluster of cases were observed with users of battery-operated or superheating devices presenting with multiple symptoms, such as dyspnea, cough, fever, constitutional symptoms, gastrointestinal upset, and hemoptysis, that is now termed e-cigarette, or vaping, product use-associated lung injury (EVALI). The Centers for Disease Control and Prevention reported 2807 cases within the USA leading to at least 68 deaths as of February 18, 2020. The heterogeneous presentations of EVALI make di...
Source: Annals of Thoracic Medicine - January 25, 2023 Category: Respiratory Medicine Authors: Brian Soto Louis Costanzo Anoop Puskoor Nada Akkari Patrick Geraghty Source Type: research

Sodium bicarbonate buffer for weaning from venovenous extracorporeal membrane oxygenation in patients with hypercapnic respiratory failure and acute renal failure
Sua Kim, Jinwook Hwang, Je Hyeong KimAnnals of Thoracic Medicine 2022 17(4):237-240 Although the routine use of alkali buffer is not recommended in patients with respiratory acidosis, some patients may benefit from its administration. A 42-year-old man was treated with venovenous extracorporeal membrane oxygenation (VV-ECMO) and continuous venovenous hemodiafiltration (CVVHDF) due to necrotizing pneumonia and emphysematous cystitis with Klebsiella pneumoniae. Although the sweep gas flow rate of the VV-ECMO was gradually reduced, he failed to wean off VV-ECMO due to respiratory acidosis, followed by tachycardia and tachypn...
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Sua Kim Jinwook Hwang Je Hyeong Kim Source Type: research

Coinfection of pulmonary tuberculosis with other lower respiratory tract infections: A retrospective cross-sectional study
CONCLUSIONS: The identification of host-related risk factors for LRTI development among patients with PTB could be used to develop a prediction model for LRTI development. Hence, initiating antimicrobials early, in parallel with appropriate anti-TB treatment, may mitigate PTB-related health and economic consequences. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Marwh G Aldriwesh Raghad A Alaqeel Aisha M Mashraqi Mutaib M Mashraqi Bayan A Albdah Azzah S Alharbi Source Type: research

Clinical characteristics and risk factors for mortality of hospitalized cancer patients with COVID-2019 in Mecca, Saudi Arabia
CONCLUSION: Hospitalized cancer patients with COVID-19 have a high mortality rate. Our study finds a correlation between multiple independent risk factors and mortality. Patients with dyspnea, leukocytosis, systemic steroid use, or secondary bacterial infection require more care, attention, and possibly more aggressive treatment. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Nabil Ghaleb Adeeb Bulkhi Eid Al-Qurashi Abdelfattah Touman Ahmad Aldobyany Rajaa Z Alsaggaf Hanan Mabar Noureen H Murtaza Ammar Rajab Source Type: research

The efficiency of high-flow nasal cannula for adult patients with coronavirus disease 19 in Jeddah, Saudi Arabia
CONCLUSIONS: According to the success rate of HFNC, which was considered a positive outcome, there might be a promising intervention for HFNC to prevent the risk of intubation and decrease the mortality rate. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Majid S Al-Thaqafy Saleh Alzahrani Abdulwahab Alghamdi Saleh Alselemi Khalid Alshebani Bussma Ahmed Bugis Alaa Bugis Ali S Al-Shareef Source Type: research

Comparing the characteristics of positional and nonpositional sleep apnea patients among the Jordanian population
CONCLUSION: POSA is common among OSA patients and demonstrates different clinical characteristics in comparison to NPOSA. Future prospective studies are needed to better characterize the POSA patients and investigate the benefit of positional therapy. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Khaled Al Oweidat Ahmad A Toubasi Asma S Albtoosh Eyad Al-Mefleh Manar M Hasuneh Ahmed A Abdulelah Rima A Sinan Source Type: research

Acute chest syndrome in pediatric sickle cell disease: A 19-year tertiary center experience
CONCLUSION: This study has reported the most common clinical characteristics and management of ACS among pediatric SCD patients in the Eastern province of KSA. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Abdullah A Yousef Hwazen A Shash Ali N Almajid Ammar A Binammar Hamza Ali Almusabeh Hassan M Alshaqaq Mohammad H Al-Qahtani Waleed H Albuali Source Type: research

Incidence and profile of severe exacerbations of chronic obstructive pulmonary disease due to biomass smoke or tobacco
CONCLUSION: AECOPD are similar events for B-COPD and T-COPD and should be managed similarly. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Rafael Golpe Nagore Blanco-Cid David Dacal-Rivas Irene Mart & #237;n-Robles Iria Veiga Indhira Guzm & #225;n-Peralta Olalla Castro-A & #241; & #243;n Luis A P & #233;rez-de-Llano Source Type: research

Lung cancer screening in the gulf: Rationale and recommendations
Sami M Bennji, B Jayakrishnan, Adil H Al-Kindi, Issa Al-Jahdhami, Zamzam Al-HashamiAnnals of Thoracic Medicine 2022 17(4):189-192 Lung cancer is the leading cause of cancer-related death worldwide among both men and women. Although advances in therapy have been made, the 5-year survival rates for lung cancer remain poor, ranging from 10% to 20%. One of the main reasons is late presentation, as only 25% of patients are amenable to cure at the time of presentation. Therefore, the emphasis on lung cancer screening (LCS) is growing with the current evidence that has shown benefits with low-dos...
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Sami M Bennji B Jayakrishnan Adil H Al-Kindi Issa Al-Jahdhami Zamzam Al-Hashami Source Type: research