American Journal of Perinatology Reports This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Lung Protective Ventilation during Pregnancy: An Observational Cohort Study
Conclusion LTVV was utilized more often than HTVV among pregnant women in all trimesters. There was a high prevalence of maternal and fetal morbidity and fetal mortality among our cohort. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - April 16, 2024 Category: Perinatology & Neonatology Authors: Kislovskiy, Yasaswi Hauspurg, Alisse Donadee, Chenell Sakamoto, Sara Murugan, Raghavan Tags: Original Article Source Type: research

Group B Streptococcus Brain Abscess in a Neonate with Bilateral Otorrhea
Conclusion Brain abscess can occur as a sequela of GBS meningitis in neonates, but they are rare. Otogenic infections require prompt evaluation and treatment as they can progress to serious central nervous infections in neonates. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - April 4, 2024 Category: Perinatology & Neonatology Authors: Spencer, Emily E. Nostrand, Sarah Van Arya, Shreyas Tags: Case Report Source Type: research

Double-Filtration Plasmapheresis and High-Dose Intravenous Immunoglobulin Therapy in a Case of Anti-M Alloimmunization
AJP Rep 2024; 14: e101-e105 DOI: 10.1055/s-0043-1777995Hemolytic disease is a common cause of fetal morbidity and mortality. The anti-M blood cell alloantibodies are one of the most severe causes of fetal anemia and intrauterine death. Since no standard treatment method has been established for pregnant women, the management of this pathology is through conventional methods used for treating Rh blood-type alloimmunization. For the first time, we report a unique case wherein a pregnant woman who had intrauterine fetal death in two previous pregnancies with very low titers of anti-M antibodies had negative effects during ver...
Source: American Journal of Perinatology Reports - April 4, 2024 Category: Perinatology & Neonatology Authors: Yasuda, Shun Ono-Okutsu, Miho Fukuda, Toma Kyozuka, Hyo Fujimori, Keiya Tags: Case Report Source Type: research

Pregnancy-Associated Atypical Hemolytic Uremic Syndrome: A Case Report with MCP Gene Mutation and Successful Eculizumab Treatment
We present a case of a 25-year-old primigravida who experienced severe preeclampsia and HELLP syndrome followed by the development of complicated P-aHUS during the early postpartum period. The patient exhibited severe clinical manifestations, including hypertensive emergency, central nervous system involvement, renal impairment, and microangiopathic hemolytic anemia. Timely initiation of eculizumab therapy resulted in successful disease remission. Further genetic analysis revealed a likely rare pathogenic MCP gene variant. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle ...
Source: American Journal of Perinatology Reports - February 21, 2024 Category: Perinatology & Neonatology Authors: Dom ínguez-Vargas, Alex Ari ño, Fanny Silva, Diana Gonz ález-Tórres, Henry J. Aroca-Martinez, Gustavo Egea, Eduardo Musso, Carlos G. Tags: Case Report Source Type: research

A Case of an Obstructed Delivery by a Large, Lower Uterine Segment Fibroid Interlocked with a Fetal Mentum
We describe a case of an obstructed delivery by a large fibroid. A 37-year-old G2P1001 with a 10-cm anterior, lower uterine segment fibroid presented for labor induction. Labor was complicated by arrest of descent due to suspected obstruction of the fetal body by the fibroid after descent of the fetal head, and delivery during cesarean section was complicated by apparent interlocking of the fetal mentum with the fibroid. Large, anterior lower uterine segment fibroids have the potential to obstruct delivery of the fetal head or of the fetal body, and these patients should be counseled regarding the potential for complicatio...
Source: American Journal of Perinatology Reports - February 21, 2024 Category: Perinatology & Neonatology Authors: Miller, Sarah E. Miller, Hayley E. Waldrop, Anne R. Karakash, Scarlett D. Shaw, Kate A. Tags: Case Report Source Type: research

Urinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli
Conclusion Escherichia coli infections progress to pyelonephritis in pregnancy at markedly higher rates than GBS, although obstetric outcomes are similar. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Sachdeva, Sarika Rosett, Heather A. Krischak, Madison K. Weaver, Kristin E. Heine, R. Phillips Denoble, Anna E. Dotters-Katz, Sarah K. Tags: Original Article Source Type: research

Mesenchymal Stem Cells Suppress Inflammatory Cytokines in Lipopolysaccharide Exposed Preterm and Term Human Pregnant Myometrial Cells
Conclusion MSCs ameliorate LPS-mediated inflammation in preterm human myometrial cells compared with term myometrial cells. Immunomodulatory effects of MSCs mediated through anti-inflammatory cytokine regulation suggest a potential cell-based therapy for preterm birth. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Mani, Arunmani Hotra, John Blackwell, Sean C. Goetzl, Laura Refuerzo, Jerrie S. Tags: Original Article Source Type: research

Spontaneous Heterotopic Cesarean Scar Triplet Gestation Following Uterine Ablation
AJP Rep 2024; 14: e91-e95 DOI: 10.1055/s-0044-1779654Heterotopic triplet pregnancy, cesarean scar ectopic pregnancy, and pregnancy following uterine ablation are all rare events that confer significant morbidity including spontaneous abortion, intrauterine fetal demise, preterm labor, abnormal placentation, and uterine rupture. A woman in her 30s, G6P4014, with a history of uterine ablation presented with delayed menses and vaginal spotting with imaging showing two intrauterine pregnancies (one with cardiac activity) and one live pregnancy at the cesarean scar. The patient was extensively counseled on risk to her and to th...
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Aldrich, Zane Frazer Ow, Rena Modii, Khyaati O'Leary, Timothy Tags: Case Report Source Type: research

Buprenorphine Induction Using Microdosing for the Management of Opioid Use Disorder in Pregnancy
Conclusion Buprenorphine microdosing was well tolerated in this patient and avoided withdrawal symptoms in the mothers, and NOWS. A microdosing study in pregnancy is indicated [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Patel, Neil B. Parilla, Barbara V. Tags: Case Report Source Type: research

A Case of an Obstructed Delivery by a Large, Lower Uterine Segment Fibroid Interlocked with a Fetal Mentum
We describe a case of an obstructed delivery by a large fibroid. A 37-year-old G2P1001 with a 10-cm anterior, lower uterine segment fibroid presented for labor induction. Labor was complicated by arrest of descent due to suspected obstruction of the fetal body by the fibroid after descent of the fetal head, and delivery during cesarean section was complicated by apparent interlocking of the fetal mentum with the fibroid. Large, anterior lower uterine segment fibroids have the potential to obstruct delivery of the fetal head or of the fetal body, and these patients should be counseled regarding the potential for complicatio...
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Miller, Sarah E. Miller, Hayley E. Waldrop, Anne R. Karakash, Scarlett D. Shaw, Kate A. Tags: Case Report Source Type: research

Uterine Leiomyomata as a Cause of Abdominal Compartment Syndrome in the Postpartum Period
AJP Rep 2024; 14: e74-e79 DOI: 10.1055/a-2164-8100Uterine leiomyomas are common benign smooth muscle tumors that often occur during the reproductive years. Although many cases may not result in significant complications, negative pregnancy outcomes have been associated with the size and location of the fibroids. Degeneration of fibroids can occur as early as the late first trimester when they undergo significant volumetric growth, contributing to pain during pregnancy. While myomectomy is typically avoided during pregnancy, conservative management with anti-inflammatory medications may be effective. Surgical removal or pre...
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Hui, Mason Sibai, Baha Montealegre, Alvaro Leon, Mateo G. Tags: Case Report Source Type: research

A Pregnant Adolescent with COVID-19 and Multisystem Inflammatory Syndrome in Children
We report a case of a pregnant adolescent with COVID-19 and MIS-C with a favorable outcome. This case highlights the considerations in managing a critically ill pregnant patient with a novel illness and the importance of a multidisciplinary team in coordinating care. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Trostle, Megan E. Grossman, Tracy B. Penfield, Christina A. Phoon, Colin K. L. Raabe, Vanessa N. Sloane, Mark F. Roman, Ashley S. Tags: Case Report Source Type: research

Likely Vertical Transmission of Neonatal SARS CoV-2 Infection
We present a case of likely intrauterine transmission of a neonate born to a mother who was recently symptomatic with a positive SARS CoV-2 polymerase chain reaction (PCR). The parturient complained of decreased fetal movement and presented at 312/7 weeks' gestation with a biophysical profile score of 2/10 and required an emergency cesarean delivery. The neonate went on to develop severe leukopenia with signs of sepsis with a positive SARS CoV-2 PCR on day 4 of life and an otherwise pan-negative workup. Meeting criteria for transplacental transmission requires timely collection of several diagnostic studies that are not st...
Source: American Journal of Perinatology Reports - February 18, 2024 Category: Perinatology & Neonatology Authors: Robinson, Andre A. Feder, Samantha Krishna, Sushma Brustman, Lois Tags: Case Report Source Type: research

Maternal and Neonatal Morbidities by Race in College-Educated Women
Conclusion In this cohort, the odds of cesarean-related maternal and neonatal morbidities were significantly higher for college-educated non-Hispanic black women, compared with their non-Hispanic white counterparts. This demonstrates that even among women with higher level education, racial and ethnic disparities persist in obstetric outcomes. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - January 29, 2024 Category: Perinatology & Neonatology Authors: Kern-Goldberger, Adina R. Madden, Nigel Baptiste, Caitlin Friedman, Alexander Gyamfi-Bannerman, Cynthia Tags: Original Article Source Type: research

The Combined Influence of Maternal Medical Conditions on the Risk of Primary Cesarean Delivery
Conclusion A greater number of maternal medical comorbidities during pregnancy is associated with increasing cumulative risk of primary cesarean delivery. These data may be useful in counseling patients on risk of cesarean during pregnancy. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - January 23, 2024 Category: Perinatology & Neonatology Authors: Fresch, Robert Stephens, Kendal DeFranco, Emily Tags: Original Article Source Type: research