Association Between Quantitative and Qualitative Imaging Biomarkers and Geographic Atrophy Growth Rate
Advanced age-related macular degeneration is one of the leading causes of blindness in the United States and worldwide.1 The advanced non-neovascular stage is characterized by the presence of geographic atrophy (GA), or complete retinal pigment epithelium and outer retina atrophy (cRORA), defined by atrophy of the retinal pigment epithelium (RPE) and retinal photoreceptors in the macula.2 As GA enlarges over time this leads to an irreversible decline in visual function and patient-reported outcomes. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 27, 2024 Category: Opthalmology Authors: Talisa E. de Carlo Forest, Zafar Gill, Andres Lisker-Cervantes, Ramya Gnanaraj, Nathan Grove, Jennifer L. Patnaik, Anne M. Lynch, Alan G. Palestine, Marc Mathias, Niranjan Manoharan, Naresh Mandava Source Type: research

Correlation of Refractive Error with Anisometropia Development in Early Childhood
This study aims to investigate the relationship between the type and severity of refractive error and anisometropia development in preschool children. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 27, 2024 Category: Opthalmology Authors: Michael Kinori, Itay Nitzan, Naava Sadi Szyper, Asaf Achiron, Oriel Spierer Tags: Original Articles Source Type: research

Retinal Ischemic Perivascular Lesions are associated with myocardial infarction in patients with coronary artery disease.
Retinal ischemic perivascular lesions (RIPLs) are anatomical biomarkers of retinal ischemia. They are defined on spectral domain optical coherence tomography (SD-OCT) by an area of focal retinal thinning in the middle retina or inner nuclear layer.1 RIPLs are a legacy of paracentral acute middle maculopathy (PAMM) due to INL infarction and were previously referred to as resolved or chronic PAMM lesions until Long et al proposed the better term “RIPL”.1–3 (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 27, 2024 Category: Opthalmology Authors: Elodie Bousquet, Ahmad Santina, Adrian Au, Swathi Somisetty, Neda Abraham, Shilo Voichanski, Rania Estawro, Yousef A. Fouad, Veronica Romero-Morales, Mathieu F Bakhoum, David Sarraf Tags: Original Articles Source Type: research

Racial Disparities in Glaucoma Vision Outcomes and Eye Care Utilization: An IRIS ® Registry Analysis
To evaluate racial disparities in vision outcomes and eye care utilization among glaucoma patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 26, 2024 Category: Opthalmology Authors: Elizabeth C. Ciociola, Sayuri Sekimitsu, Sophie Smith, Alice C. Lorch, Joan W. Miller, Tobias Elze, Nazlee Zebardast Tags: Original Articles Source Type: research

IQCB1 (NPHP5)-retinopathy: Clinical and Genetic Characterization and Natural History
: To describe the clinical and genetic features, and explore the natural history of retinopathy associated with IQCB1 variants in children and adults with retinopathy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 22, 2024 Category: Opthalmology Authors: Sagnik Sen, Lorenzo Fabozzi, Kaoru Fujinami, Yu Fujinami-Yokokawa, Genevieve A. Wright, Andrew Webster, Omar Mahroo, Anthony G. Robson, Michalis Georgiou, Michel Michaelides Tags: Original Articles Source Type: research

External Validation of a Model to Predict Postoperative Globe Axial Length in Children after Bilateral Cataract Surgery
To perform the external validation of a model to predict postoperative axial length (AL) in children undergoing bilateral cataract surgery with primary intraocular lens (IOL) implantation older than 2 years. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 21, 2024 Category: Opthalmology Authors: Antonio Carlos Lottelli, Rupal H. Trivedi, Eliane Chaves Jorge, M. Edward Wilson Tags: Original Articles Source Type: research

Eight Years and Beyond Longitudinal Changes of Peripapillary Structures on OCT in Adult Myopia
To investigate the long-term changes of peripapillary structures detected by enhanced depth imaging of OCT in adult myopia. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 21, 2024 Category: Opthalmology Authors: Yi Dai MD, PhD, Li Wang MD, PhD, Jie Hong MS, Xinghuai Sun MD, PhD Tags: Original Articles Source Type: research

Neuropathic corneal pain: Tear proteomic and neuromediator profiles, imaging features, and clinical manifestations
To investigate the tear proteomic and neuromediator profiles, in vivo confocal microscopy (IVCM) imaging features, and clinical manifestations in neuropathic corneal pain (NCP) patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 21, 2024 Category: Opthalmology Authors: Chang Liu, Molly Tzu-Yu Lin, Isabelle Xin Yu Lee, Jipson Hon Fai Wong, Daqian Lu, Thomas Chuen Lam, Lei Zhou, Jodhbir S. Mehta, Hon Shing Ong, Marcus Ang, Louis Tong, Yu-Chi Liu Tags: Original Articles Source Type: research

Peripheral vision in patients following intraocular lens implantation: a systematic review and meta-analysis
To revise the literature on peripheral optics and vision following intraocular lens (IOLs) implantation. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 21, 2024 Category: Opthalmology Authors: Pablo Artal, Maria Arvaniti, Panaghiota Dimou, Costas Stavrinos, Harilaos Ginis, Luc ía Hervella, José Luis Güell Source Type: research

Comparison of Legacy and New No-History IOL Power Calculation Formulas in Post-Myopic Laser Vision Correction Eyes
In contemporary ophthalmic practice, clinicians frequently encounter patients with visually significant cataracts who have undergone previous myopic laser vision correction (M-LVC). Accurate determination of intraocular lens (IOL) power in M-LVC eyes poses a challenge, leading to less accurate refractive outcomes than non-M-LVC eyes.1 One factor contributing to this discrepancy is that the effective lens position (ELP) tends to be more posterior than anticipated, based on the altered keratometry, resulting in a more-than-intended hyperopic refractive outcome. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Abdelrahman M. Anter, Adam R. Bleeker, H. John Shammas, Sanjana Suraneni, Brandon Kingrey, David A Murphy, Sebastian Leal, Seyyedehfatemeh Ghalibafan, Rahul S. Tonk, David L. Cooke, Kamran M. Riaz Tags: Original Articles Source Type: research

Retinal hemorrhages with Valsalva during laser photocoagulation in previously treated ROP
An 8-month-old girl born at gestational age 22+5 weeks and birth weight 470 grams received three intravitreal anti-VEGF injections for recurrent Type 1 ROP at postmenstrual age (PMA) 32 weeks, 40+3 weeks, and 50 weeks. At 60 weeks PMA, she had persistent posterior vascular tortuosity and extensive peripheral avascular retina. The decision was made to perform retinal laser photocoagulation under general endotracheal anesthesia. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Tiffany A Chen, Julius T Oatts, Alejandra G de Alba Campomanes Tags: Illustrations & Insights Source Type: research

Diagnostic Utility of QuantiFERON-Gold Testing in Patients with Ocular Inflammation in a Low-Endemic Tuberculosis Region
To evaluate the diagnostic value of QuantiFERON Gold (QFT-G) testing for ocular inflammation in a low prevalence tuberculosis (TB) area. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Julia Xia, Alan G. Palestine, Amit K. Reddy Tags: Original Articles Source Type: research

Efficacy and Safety of Lotilaner Ophthalmic Solution (0.25%) for the Treatment of Demodex Blepharitis: A GRADE Assessed Systematic Review and Meta-Analysis of Observational & Experimental Studies
This review aims to assess the safety and efficacy of Lotilaner in the treatment of Demodex Blepharitis. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 19, 2024 Category: Opthalmology Authors: Muhammad Talha, Mohammad Haris Ali, Eeshal Fatima, Arsalan Nadeem, Abdullah Ahmed, Abdulqadir J. Nashwan Source Type: research

A Randomized, Controlled Comparison of NCX 470, a Nitric Oxide-Donating Bimatoprost, and Latanoprost in Subjects with Open-Angle Glaucoma or Ocular Hypertension: The MONT BLANC Study
To compare intraocular pressure (IOP)-lowering efficacy and safety profile of NCX 470, a nitric oxide (NO)-donating bimatoprost, to latanoprost in subjects with glaucoma or ocular hypertension. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 16, 2024 Category: Opthalmology Authors: Robert Fechtner, Steven Mansberger, James Branch, Jay Mulaney, Sara Ziebell, Krisi Lopex, Doug Hubatsch Tags: Original Articles Source Type: research

Genetic and clinical features of ABCA4-associated retinopathy in a Japanese nationwide cohort
To clarify the genetic and clinical features of Japanese patients with ABCA4-associated retinopathy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 16, 2024 Category: Opthalmology Authors: Kei Mizobuchi, Takaaki Hayashi, Koji Tanaka, Kazuki Kuniyoshi, Yusuke Murakami, Natsuko Nakamura, Kaoruko Torii, Atsushi Mizota, Daiki Sakai, Akiko Maeda, Taro Kominami, Shinji Ueno, Shunji Kusaka, Koji M Nishiguchi, Yasuhiro Ikeda, Mineo Kondo, Kazushige Source Type: research