Use of matrix-assisted laser desorption ionization time of flight (MALDI-TOF) to detect antibiotic resistance in bacteria: A scoping review
CONCLUSIONS: MALDI-TOF shows promise as a tool for AMR detection, but its readiness for wider clinical adoption relies on ongoing research, development of algorithms and software for automated interpretation of mass spectra, and validation efforts. Its role in routine clinical practice may evolve as technology and knowledge progress.PMID:38040411 | DOI:10.1093/ajcp/aqad160 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 1, 2023 Category: Pathology Authors: Gloria Viboud Holly Asaro Michael Bailou Huang Source Type: research

Identification of Hb Lepore, Hb anti-Lepore, and α-globin gene triplications by long-read single-molecule real-time sequencing
CONCLUSIONS: Conventional methods may overlook rare thalassemias or Hb variants. Long-read SMRT sequencing has the potential to identify breakpoints in fusion genes, demonstrating that it is a promising technique for detecting rare thalassemias.PMID:38037185 | DOI:10.1093/ajcp/aqad155 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 1, 2023 Category: Pathology Authors: Anping Xu Yinghui Ye Yueying Huang Yun Huang Hui Guo Ling Ji Source Type: research

Use of matrix-assisted laser desorption ionization time of flight (MALDI-TOF) to detect antibiotic resistance in bacteria: A scoping review
CONCLUSIONS: MALDI-TOF shows promise as a tool for AMR detection, but its readiness for wider clinical adoption relies on ongoing research, development of algorithms and software for automated interpretation of mass spectra, and validation efforts. Its role in routine clinical practice may evolve as technology and knowledge progress.PMID:38040411 | DOI:10.1093/ajcp/aqad160 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 1, 2023 Category: Pathology Authors: Gloria Viboud Holly Asaro Michael Bailou Huang Source Type: research

Survey and situation analysis of personal, employer-related, and environmental factors affecting participation in continuous professional development (CPD) programs of laboratory professionals in Africa
CONCLUSIONS: The CPD programs are considered useful to an individual's professional development, although there was low participation. It is recommended that different formats and platforms be used to expand CPD programs.PMID:38035716 | DOI:10.1093/ajcp/aqad154 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 30, 2023 Category: Pathology Authors: Nqobile Ndlovu Anafi Mataka Carl Lombard Rajiv T Erasmus Annalise E Zemlin Source Type: research

Presence of 10 transformation zone cells in endocervical curettage should not be required for adequacy
CONCLUSIONS: We found that the presence of at least 10 EC/TZ cells does not increase the likelihood of finding HGD in an ECC performed in the 6 months prior to a LEEP with HGD. Similar to the use of the TZ component in cervical Papanicolaou smears, the presence or absence of at least 10 TZ cells in an ECC should only be considered a quality assurance measure and not be used as a criterion for adequacy of the specimen.PMID:38035727 | DOI:10.1093/ajcp/aqad157 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 30, 2023 Category: Pathology Authors: Roa Alqabbani Joanna Chan Allison Goldberg Source Type: research

A mixed-methods study on the use of a nongynecological virtual microscopy platform in cytology education
CONCLUSIONS: The VM results were poorer compared with LM in our validation. Its use seems promising, but more focus is needed to improve the VM screening platform.PMID:38006327 | DOI:10.1093/ajcp/aqad156 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 25, 2023 Category: Pathology Authors: Paul Z Chiou Yuane Jia Source Type: research

A mixed-methods study on the use of a nongynecological virtual microscopy platform in cytology education
CONCLUSIONS: The VM results were poorer compared with LM in our validation. Its use seems promising, but more focus is needed to improve the VM screening platform.PMID:38006327 | DOI:10.1093/ajcp/aqad156 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 25, 2023 Category: Pathology Authors: Paul Z Chiou Yuane Jia Source Type: research

A mixed-methods study on the use of a nongynecological virtual microscopy platform in cytology education
CONCLUSIONS: The VM results were poorer compared with LM in our validation. Its use seems promising, but more focus is needed to improve the VM screening platform.PMID:38006327 | DOI:10.1093/ajcp/aqad156 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 25, 2023 Category: Pathology Authors: Paul Z Chiou Yuane Jia Source Type: research

A mixed-methods study on the use of a nongynecological virtual microscopy platform in cytology education
CONCLUSIONS: The VM results were poorer compared with LM in our validation. Its use seems promising, but more focus is needed to improve the VM screening platform.PMID:38006327 | DOI:10.1093/ajcp/aqad156 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 25, 2023 Category: Pathology Authors: Paul Z Chiou Yuane Jia Source Type: research

A mixed-methods study on the use of a nongynecological virtual microscopy platform in cytology education
CONCLUSIONS: The VM results were poorer compared with LM in our validation. Its use seems promising, but more focus is needed to improve the VM screening platform.PMID:38006327 | DOI:10.1093/ajcp/aqad156 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 25, 2023 Category: Pathology Authors: Paul Z Chiou Yuane Jia Source Type: research

Diagnostic impact of RNA-based next-generation sequencing fusion panel for solid tumors: A single-institution experience
CONCLUSIONS: In summary, this study demonstrated the feasibility and utility of an RNA-based NGS fusion panel for a wide variety of solid tumors in the appropriate clinicopathologic context. These findings warrant further validation in larger studies involving multiple institutional patient cohorts.PMID:38001052 | DOI:10.1093/ajcp/aqad148 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 24, 2023 Category: Pathology Authors: Fei Fei Christian A Kunder Chandler Ho James L Zehnder Gianna Tomasello Eula Fung Carlos J Suarez Source Type: research

Correction to: IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas
Am J Clin Pathol. 2023 Nov 22:aqad173. doi: 10.1093/ajcp/aqad173. Online ahead of print.NO ABSTRACTPMID:37991998 | DOI:10.1093/ajcp/aqad173 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 22, 2023 Category: Pathology Source Type: research

Correction to: IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas
Am J Clin Pathol. 2023 Nov 22:aqad173. doi: 10.1093/ajcp/aqad173. Online ahead of print.NO ABSTRACTPMID:37991998 | DOI:10.1093/ajcp/aqad173 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 22, 2023 Category: Pathology Source Type: research

Correction to: IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas
Am J Clin Pathol. 2023 Nov 22:aqad173. doi: 10.1093/ajcp/aqad173. Online ahead of print.NO ABSTRACTPMID:37991998 | DOI:10.1093/ajcp/aqad173 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 22, 2023 Category: Pathology Source Type: research

Cytologic analysis of metaplastic breast carcinoma: Review of 66 cases diagnosed at the Institut Curie
CONCLUSIONS: Fine-needle aspiration holds considerable potential as a valid, independent, and complementary approach to histologic examination of MBC.PMID:37987613 | DOI:10.1093/ajcp/aqad144 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 21, 2023 Category: Pathology Authors: Adam Kowalewski Jerzy Klijanienko Source Type: research