ZyVersa Therapeutics Appoints Three New Board Members
New appointments bring expertise and proven leadership to ZyVersa to support advancement and development of VAR 200 for renal disease, and IC 100 for inflammatory diseases
WESTON, Fla., Jan. 5, 2023 -- (Healthcare Sales & Marketing Network) -- ZyVersa ... Biopharmaceuticals, Personnel ZyVersa Therapeutics, glomerulosclerosis, Alport Syndrome, Kidney Disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 5, 2023 Category: Pharmaceuticals Source Type: news
FDA Rejects Bardoxolone as First Alport Syndrome Agent FDA Rejects Bardoxolone as First Alport Syndrome Agent
Alport syndrome, a rare genetic disease that causes early kidney failure, continues to have no approved treatment, but advocates foresee progress in diagnosis and awareness from the failed approval attempt.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - March 15, 2022 Category: Transplant Surgery Tags: Nephrology News Source Type: news
Reata Pharmaceuticals Receives Complete Response Letter From The FDA for Bardoxolone for the Treatment of Patients with Chronic Kidney Disease Caused by Alport Syndrome
PLANO, Texas--(BUSINESS WIRE) February 25, 2022 -- Reata Pharmaceuticals, Inc. (Nasdaq: RETA) (“Reata,” the“Company,” or“we”), today announced that the U.S. Food and Drug Administration (“FDA”) has... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - February 25, 2022 Category: Drugs & Pharmacology Source Type: news
Reata Pharmaceuticals Announces Outcome of FDA Advisory Committee Meeting of Bardoxolone for the Treatment of Patients with Chronic Kidney Disease Caused by Alport Syndrome
PLANO, Texas--(BUSINESS WIRE) December 8, 2021 -- Reata Pharmaceuticals, Inc. (Nasdaq: RETA) (“Reata,” the“Company,” or“we”), today announced the outcome of the U.S. Food and Drug Administration... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - December 8, 2021 Category: Drugs & Pharmacology Source Type: news
Reata Announces FDA Accepted for Filing the NDA for Bardoxolone for the Treatment of Patients With Chronic Kidney Disease Caused by Alport Syndrome
PLANO, Texas, April 26, 2021 (GLOBE NEWSWIRE) -- Reata Pharmaceuticals, Inc. (Nasdaq: RETA) (“Reata,” the“Company,” or“we”), a clinical-stage biopharmaceutical company, today announced that the U.S. Food and... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - April 26, 2021 Category: Drugs & Pharmacology Source Type: news
Reata Pharmaceuticals, Inc. Submits NDA for Company ’s Lead Program: Bardoxolone in Alport Syndrome
PLANO, Texas, March 01, 2021 (GLOBE NEWSWIRE)— Reata Pharmaceuticals, Inc. (Nasdaq: RETA) (“Reata,” the“Company,” or“we”), a clinical-stage biopharmaceutical company, today announced... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 1, 2021 Category: Drugs & Pharmacology Source Type: news
Variant Pharmaceuticals Secures $10 Million in Financing from Korean Company, Incon Co., Ltd.
Funds will accelerate clinical development of VAR 200, 2-hydroxypropyl-beta-cyclodexrtrin (2HPβCD), for treatment of focal segmental glomerulosclerosis (FSGS), a rare kidney disease
Incon's investment in Variant expands their biopharmaceutical busi... Biopharmaceuticals, Venture Capital, Personnel Variant Pharmaceuticals, Glomerulosclerosis, Alport Syndrome (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 3, 2018 Category: Pharmaceuticals Source Type: news
A highly sensitive and multi-analytical system for hereditary kidney disease
(Kumamoto University) Alport syndrome (AS) is a hereditary kidney disease caused by protein (collagen) abnormalities. Unfortunately, treatment through the correction of collagen functionality has not yet been developed. Now, Japanese researchers have established a method to assess collagen complex integrity in AS, making it possible to develop therapeutic drugs. This detection system reduces labor and time costs compared to conventional methods, and can monitor type IV collagen functionality with high sensitivity. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 9, 2018 Category: Biology Source Type: news
Grandfather's family uses Facebook to find him a kidney
Dan Desmarais, 60, from Sandwich, Massachusetts, suffers from Alport Syndrome, a genetic condition that causes loss of kidney function, and is in the late stages of renal failure. (Source: the Mail online | Health)
Source: the Mail online | Health - February 2, 2018 Category: Consumer Health News Source Type: news
Genetic Testing Using a SRNS Gene Panel Genetic Testing Using a SRNS Gene Panel
The authors developed a targeted next-generation sequencing gene panel assay for diagnostic testing in steroid-resistant nephrotic syndrome or suspected Alport syndrome.Journal of Medical Genetics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 15, 2017 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news
What is the Genetic Inheritance of Alport Syndrome?
Discussion
Alport Syndrome is a genetic disease classically associated with progressive renal disease often leading to end stage renal disease, variable sensory neuronal deafness and ocular findings (perimacular retinopathy).
A. Cecil Alport built on the work of others evaluating families with nephritis and/or hematuria. However he very clearly describes the third generation of a family with an X-linked dominant pattern and also emphasizes the syndrome’s associated deafness.
Alport writes:
“It will be seen from this that nearly all the children of three generations of one family suffer from hematuria or nep...
Source: PediatricEducation.org - August 28, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Regulus Announces Pipeline Updates and Advancements
Phase II RG-012 HERA and Renal Biopsy studies for Alport syndrome move forward
Discontinuing clinical development of RG-101
Pre-clinical pipeline progresses
LA JOLLA, Calif., June 12, 2017 -- (Healthcare Sales & Marketing Network) -- Regulus Ther... Biopharmaceuticals Regulus Therapeutics, microRNAs (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 12, 2017 Category: Pharmaceuticals Source Type: news
Reata initiates Phase II/III trial of bard to treat Alport Syndrome-caused CDK
US-based clinical-stage biopharmaceutical company Reata Pharmaceuticals has initiated patient screening in a Phase II/III trial of bardoxolone methyl (bard) for the treatment of patients with chronic kidney disease (CKD) caused by Alport syndrome. (Source: Drug Development Technology)
Source: Drug Development Technology - February 27, 2017 Category: Pharmaceuticals Source Type: news
Guy Reveals To His Buddy He's A Kidney Match. Cue Happy Tears
This is an amazingly heartfelt and hilarious moment.
Danny Kolzow, a 23-year-old nurse in Texas who has Alport Syndrome, experienced loss of kidney function and needed a transplant. So when his friend Graham McMillan found out he was a match, the soon-to-be-donor decided to to break the big news in the most perfect way.
“I heard urine need of a kidney, want mine?”
McMillan, 24, showed up to Baylor All Saints Medical Center in Fort Worth, Texas with a sign that read “I heard urine need of a kidney, want mine?” and shocked the grateful Kolzow. The emotional reveal was caught on video ...
Source: Healthy Living - The Huffington Post - July 28, 2016 Category: Consumer Health News Source Type: news
What It Means When You See Blood In Your Urine
There are few moments more frightening than seeing blood in your urine. Happily, the cause is often not serious.
The condition is more formally known as hematuria, and blood in the urine is usually the only symptom. Note that it does not take much blood to color urine pink or red, and the bleeding is usually not painful. Certain foods - notably rhubarb and beets - can also turn your urine a reddish color.
In all instances of detecting blood in your urine, see a doctor. It is symptomatic of a number of ailments, including:
• An enlarged prostate. As this gland begins to grow - commonly with the onset of middle age in m...
Source: Healthy Living - The Huffington Post - July 27, 2016 Category: Consumer Health News Source Type: news
