Secondary Polycythemia and Non-Islet Cell Tumor-induced Hypoglycemia in Advanced Hepatocellular Carcinoma: A Case Report
Acta Med Indones. 2024 Jan;56(1):93-101.ABSTRACTContinuously holding its position as the sixth most common cause of cancer and the third leading cause of cancer death, globally, Hepatocellular Carcinoma (HCC) remains as a healthcare priority. Production of various substances may result into systemic or metabolic complications, often known as paraneoplastic phenomena of HCC. A 56-year-old male with history of untreated chronic hepatitis B arrived with generalized weakness and intermittent headache in the last two days prior to admission. Laboratory findings demonstrated elevated hemoglobin (20.5 g/dl), alpha-fetoprotein (29...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Maria Satya Paramitha Dekta Filantropi Esa Ni Made Hustrini Nadia Ayu Mulansari Irsan Hasan Agnes Stephanie Harahap Source Type: research
Validation of Drug Resistance in Pneumonia (DRIP) Score as Empirical Antibiotic Failure Predictor in Community-Acquired Pneumonia Patients in Cipto Mangunkusumo Hospital
CONCLUSION: The DRIP score has low accuracy performance and calibration value in predicting empirical antibiotic failure and poor discriminatory value.PMID:38561875 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Rohayat Bilmahdi Simanjuntak Khie Chen Lie Cleopas Martin Rumende Murdani Abdullah Hamzah Shatri Soekamto Koesnoe Leonard Nainggolan Aulia Rizka Source Type: research
The Association between Anemia and Mortality of Severe Pneumonia COVID-19 Patients in the High Care Unit of a Tertiary Hospital in Jakarta
CONCLUSION: There is a significant association between anemia at HCU admission and mortality in patients with severe pneumonia COVID-19 during hospitalization.PMID:38561876 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Wulyo Rajabto Gurmeet Singh Calvin Kurnia Mulyadi Vitya Chandika Maria Pyrhadistya Source Type: research
Gaucher Disease: A First Reported Adult Case in Indonesia
Acta Med Indones. 2024 Jan;56(1):69-75.ABSTRACTA 44-year-old female presented with a distended abdomen and fatigue. On physical examination, prominent splenomegaly was found. The laboratory investigations revealed pancytopenia and decreased albumin-globulin ratio. The abdominal ultrasonography revealed splenomegaly, cholelithiasis, and cystitis, and the bone survey showed osteopenia. Differential diagnoses included leukemia, multiple myeloma, and myelofibrosis therefore bone marrow puncture was performed. However, histopathologic examination found Gaucher-like cells in the bone marrow aspiration. The finding of CD68 positi...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Ardhi Rahman Ahani Cosphiadi Irawan Agnes Stephanie Harahap Klara Yuliarti Maria Francisca Ham Faramitha Nur Izzaty Damayanti Rusli Sjarif Source Type: research
MPox Skin Lesions
We present two different spectrums of Mpox skin lesions in patients living with HIV, with a positive polymerase chain reaction test for Mpox. The first patient is a 48-year-old male, who developed a maculopapular lesion, that was initially noticed on the face, the lesions were then spread to the back and hand. He identifies as men who have sex with men and living with HIV for the past 18 years. There were no lesions on the genitalia or mucosa. The second patient is a 28-year-old male, the initial symptom was fever, followed by skin lesions after around 1 week of fever. The lesion initially appears as pustules on the face a...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Robert Sinto Alvin Johan Hanny Nilasari Evy Yunihastuti Erni J Nelwan Source Type: research
Insulin Use and The Risk of Hepatocellular Carcinoma: Insights and Implications
Acta Med Indones. 2024 Jan;56(1):107-113.ABSTRACTIn recent years, the incidence of diabetes mellitus and hepatocellular carcinoma (HCC) has been increasing worldwide, in the context of an increasing prevalence of non-alcoholic fatty liver disease (NAFLD). In patients with diabetes mellitus, exogenous insulin is commonly prescribed and used in long-term settings. Recent studies suggest that insulin use may elevate the risk of HCC. A substantial body of work seeks to unpack the association between insulin use and the risk of developing HCC, although there may be conflicting evidence. Further validation is necessary to clarif...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Juferdy Kurniawan Maria Teressa Source Type: research
Consensus Guidelines for Influenza Vaccination in Patients with Diabetes
Acta Med Indones. 2024 Jan;56(1):126-133.ABSTRACTInfluenza is a prevalent health issue encountered in daily practice. Patients with diabetes mellitus face a higher risk of infections, including influenza, owing to the compromised immune system associated with diabetes. This susceptibility arises from the potential of diabetes mellitus to weaken the immune system. Moreover, elevated blood glucose levels can create a conducive environment for the growth of bacteria and viruses. This consensus is formulated by a multidisciplinary team to serve as practical guidance for the administration of influenza vaccinations to patients ...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Sukamto Koesnoe Anshari Saifuddin Hasibuan Ketut Suastika Cissy Kartasasmita Andi Makbul Aman Ida Ayu Kshanti Wismandari Wisnu Samsuridjal Djauzi Iris Rengganis Alvina Widhani Suzy Maria Erwanto Budi Winulyo Hindra Irawan Heri Nugroho Nanny Soetedjo Sobag Source Type: research
Proportion of Hypogonadism in Transfusion-Dependent Thalassemia Patients and Its Contributing Factors
CONCLUSION: We confirmed the role of pre-transfusion Hb count as a potential predictor for hypogonadism due to the tissue hypoxia mechanism and transfusion-related iron overload in TDT patients. Decreased Hb is linearly correlated with FSH, LH, and testosterone levels. Decreased Hb also downregulates these factors.PMID:38561881 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Dian Anindita Lubis Imam Subekti Em Yunir Cosphiadi Irawan Andon Hestiantoro Silvia Werdhy Lestari Aria Kekalih Merci Monica Br Pasaribu Santi Syafril Source Type: research
Significant Inverse Correlation of Serum Levels of Osteoprotegerin (OPG) and Transferrin Saturation in Thalassemia Dependent Transfusion (TDT) Patients
CONCLUSION: There was a significant inverse correlation between OPG with transferrin saturation in TDT patients.PMID:38561882 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Indra Wijaya M Lucky Nurdiansyah Prameswara Dimmy Prasetya Laniyati Hamijoyo Bachti Alisjahbana Andri Reza Rahmadi Source Type: research
Challenges in Diagnosis and Treatment of Male Hypogonadism
Acta Med Indones. 2024 Jan;56(1):1-2.ABSTRACTHypogonadism is a condition characterized by diminished or absent production of sex hormones by the testicles in men and the ovaries in women. Hypogonadism is classified into primary and secondary hypogonadism. Each type of hypogonadism can be caused by congenital and acquired factors. There are many factors that contribute to the occurrence of hypogonadism, including genetic and developmental disorders, infection, kidney disease, liver disease, autoimmune disorders, chemotherapy, radiation, surgery, and trauma. This represents the considerable challenge in diagnosing hypogonadi...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Dyah Purnamasari Source Type: research
The Impact on Working Conditions and Income Amongst Internists in Indonesia: Lesson Learned from the COVID-19 Pandemic
This study provides some lessons learned during the COVID-19 pandemic regarding the changes in working conditions and earnings experienced by Indonesian internists. There were 3,115 and 1,772 participants in the first and second survey, respectively. After one year, the proportion of internists handling COVID-19 cases, including critical COVID-19 cases, increased; with fewer internists over 60 years old involved. Working hours, number of patients, and monthly earnings decreased for the majority of internists. The increased workload was experienced by most participants one year of the pandemic, predominantly reported by fem...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Sally Aman Nasution Lugyanti Sukrisman Simon Salim Ni Made Hustrini Rudi Hidayat Evy Yunihastuti Ceva W Pitoyo Andhika Rachman Sayang Rahmadini Ginulur Gensyaf Adgani Nurul Inayah Rahmani Source Type: research
Impacts of the COVID-19 Pandemic on the CODE ST-Segment Elevation Myocardial Infarction Program: A Quantitative and Qualitative Analysis
CONCLUSION: The implementation of the code STEMI program during the COVID-19 pandemic revealed that modified pathways were required because of the COVID-19 screening process. According to the Donabedian model, during the pandemic, the code STEMI program's healthcare service quality decreased because of a reduction in efficacy, effectiveness, efficiency, and optimality. Despite these limitations attributed to the pandemic, the code STEMI program was able to provide good services for STEMI patients.PMID:38561885 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Eka Ginanjar Arif Mansjoer Lusiani Rusdi Rizky Ramadantie Hadiki Habib Lies Dina Liastuti Sally Aman Nasution Idrus Alwi Abdul Rashid Source Type: research
A Life-Threatening Complication During the Fourth Pregnancy Due to Acute Promyelocytic Leukemia: A Case Report
Acta Med Indones. 2024 Jan;56(1):76-83.ABSTRACTIncidents of leukemia in pregnancy are infrequent with only one case found from 75,000 to 100,000 pregnancies. The pathophysiological mechanism of leukemia during pregnancy is still unclear. Leukemia which occurs in pregnancy is usually acute and predominantly the myeloid type.A 35-year-old woman in her fourth pregnancy with a gestational age of 38-39 weeks, came to the emergency department (ED) with complaints of contractions since 4.5 hours before admission. The contraction was not accompanied by discharge, mucus, or blood, and fetal movements was still active. She denied co...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Ismy Azizah Sisnawati Kezia Salay Listiana Nur Fadillah Indi Jazilah Jessica Amelinda Mintarjo Atiyatum Billah Agung Sunarko Putra I Dewa Made Widi Hersana Citra Novita Source Type: research
Endoscopic Dilatation with Ultrathin Endoscope Assisted Method for Esophageal and Pyloric Stricture related Corrosive Injury: 4 Years Case Series Study
Acta Med Indones. 2024 Jan;56(1):84-92.ABSTRACTCorrosive injuries (CI) become medical problems related complications include esophageal, pyloric stricture and squamous cell carcinoma, physical and quality of life. Endoscopic (ED) dilatation is primary therapy. The ultrathin endoscope-assisted method is potentially safe and useful in avoiding technical failure. Describe clinical outcomes of ED ED-related CI including successful, refractory, recurrent, and complications-related procedures. Case series study of esophageal and/or pyloric stricture patients after CI who underwent dilatation at Soetomo General Hospital (July 201...
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Rusdiyana Ekawati Nurike Setyari Mudjari Arianti Arianti Annisa Zahra Mufida Budi Widodo Titong Sugihartono Herry Purbayu Source Type: research
Identifying Predictors of Mortality in Sepsis Patients with Malignancy: A Retrospective Cohort Study
CONCLUSION: SOFA score and ECOG performance status are significantly associated with sepsis patient mortality in malignancy cases.PMID:38561888 (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Leonard Nainggolan Rido Prama Eled Ikhwan Rinaldi Cleopas Martin Rumende Chyntia Olivia Maurine Jasirwan Suryo Anggoro Kusumo Wibowo Robert Sinto Khie Chen Lie Source Type: research
