Morphometric study of the legs of the main Chagas vector, Triatoma infestans (Hemiptera: Reduviidae)
We described morphometric traits and the natural variation of each leg segment. Different linear, size and shape variables of each component of the three right legs of fifth instar nymphs of T. infestans were analyzed using morphometric tools. We analyzed differentiation, variation and correlation for each segment across the fore-, mid and hind legs using different statistical approaches such as general linear model, canonical variates analysis, test of equality of coefficient of variation and partial least square analysis. We also analyzed variation and correlation between segments within each leg with partial least squar...
Source: Acta Tropica - April 22, 2024 Category: Infectious Diseases Authors: Gast ón Mougabure-Cueto Mar ía Laura Hernández Juan Jos é Gilardoni Julieta Nattero Source Type: research
Green synthesis of silver nanoparticles based on using Croton urucurana and their toxicity against freshwater snail species Biomphalaria glabrata
Acta Trop. 2024 Apr 19:107224. doi: 10.1016/j.actatropica.2024.107224. Online ahead of print.ABSTRACTGreen plant-based silver nanoparticles (GP-Ag NPs) have contributed to the development of ecological technologies with low environmental impact and safer for human health, as well as demonstrating potential for the control of vectors and intermediate hosts. However, knowledge about its toxicity in the early stages of gastropod development remains scarce. Therefore, the current study aimed to investigate the toxicity of GP-Ag NPs synthesized from Croton urucurana leaf extracts in snail species Biomphalaria glabrata, which is...
Source: Acta Tropica - April 21, 2024 Category: Infectious Diseases Authors: Paula Sampaio Ara újo Maxwell Batista Caixeta Eloiza da Silva Nunes Bruno Bastos Gon çalves Thiago Lopes Rocha Source Type: research
Effect of nanoformulation Azadirachta indica on some factors associated with the vectorial capacity and competence of Anopheles aquasalis experimentally infected with Plasmodium vivax
In conclusion, these findings suggest that the A. indica nanoformulation is a potential as a tool for malaria control through reduction in the vector longevity and reproductive capacity, possibly leading to decreased vector population densities. Moreover, the nanoformulation interfered with the sporogonic development of P. vivax. However, further basic research on Neem formulations, their effects, and mechanisms of action is imperative to gain a more specific perspective for safe field implementation.PMID:38642694 | DOI:10.1016/j.actatropica.2024.107223 (Source: Acta Tropica)
Source: Acta Tropica - April 20, 2024 Category: Infectious Diseases Authors: Paula Andrea Urrea Aguirre Keillen Monick Martins Campos Duv án Dueñas López Fernando Orozco S ánchez Alberto Tob ón Castaño Claudia Mar ía Ríos Velásquez Adriana Pab ón Vidal Source Type: research
Surveillance of mosquitoes harnessing their buzzing sound
In conclusion, the sound-based technology is simple, precise, and cost-effective and provides better resolution for species, sex, and fed-unfed status detection in comparison to conventional methods. Real-time surveillance of mosquitoes could potentially utilize this technology.PMID:38642695 | DOI:10.1016/j.actatropica.2024.107221 (Source: Acta Tropica)
Source: Acta Tropica - April 20, 2024 Category: Infectious Diseases Authors: Udita Mandal M Suman J Dutta V Dixit D S Suman Source Type: research
Combining a transcriptomic approach and a targeted metabolomics approach for deciphering the molecular bases of compatibility phenotype in the snail Biomphalaria glabrata toward Schistosoma mansoni
Acta Trop. 2024 Apr 17:107212. doi: 10.1016/j.actatropica.2024.107212. Online ahead of print.ABSTRACTBiomphalaria glabrata is a freshwater snail and the obligatory intermediate host of Schistosoma mansoni parasite, the etiologic agent of intestinal Schistosomiasis, in South America and Caribbean. Interestingly in such host-parasite interactions, compatibility varies between populations, strains or individuals. This observed compatibility polymorphism is based on a complex molecular-matching-phenotype, the molecular bases of which have been investigated in numerous studies, notably by comparing between different strains or ...
Source: Acta Tropica - April 19, 2024 Category: Infectious Diseases Authors: Elodie Simphor Anne Rognon Emmanuel Vignal Sylvain Henry Jean-Fran çois Allienne Andrei Turtoi Cristian Chaparro Richard Galinier David Duval Benjamin Gourbal Source Type: research
Identification, prioritization, and evaluation of RlpA protein as a target against multidrug-resistant Pseudomonas aeruginosa
Acta Trop. 2024 Apr 16;255:107216. doi: 10.1016/j.actatropica.2024.107216. Online ahead of print.ABSTRACTAccording to the World Health Organization, infectious diseases, particularly those caused by multidrug-resistant bacteria (MDR), are projected to claim the lives of 15 million people by 2050. Septicemia carries a higher morbidity and mortality rate than infections caused by susceptible Pseudomonas aeruginosa, and MDR-mediated ocular infections can lead to impaired vision and blindness. To identify and develop a potential drug against MDR P. aeruginosa, we employed in silico reverse genetics-based target mining, drug pr...
Source: Acta Tropica - April 18, 2024 Category: Infectious Diseases Authors: Mansour K Gatasheh Nandagopal Murugan Rajapandiyan Krishnamoorthy Mohammad A Alshuniaber Jambulingam Malathi Vetrivel Umashankar Gopinath Ramalingam Vishnu Priya Veeraraghavan Selvaraj Jayaraman Source Type: research
Characterization of drug resistance genes in Indian Plasmodium falciparum and Plasmodium vivax field isolates
Acta Trop. 2024 Apr 16:107218. doi: 10.1016/j.actatropica.2024.107218. Online ahead of print.ABSTRACTOne of the major challenges for malaria control and elimination is the spread and emergence of antimalarial drug resistance. Mutations in Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) field isolates for five drug resistance genes viz. crt, mdr1, dhps, dhfr and kelch known to confer resistance to choloroquine (CQ), sulfadoxine-pyrimethamine (SP) and artemisinin (ART) and its derivatives were analyzed. A total of 342 symptomatic isolates of P. falciparum (Pf) and P. vivax (Pv) from 1993 to 2014 were retrieved from mala...
Source: Acta Tropica - April 18, 2024 Category: Infectious Diseases Authors: Geetika Narang Jahnvi Jakhan Suman Tamang Karmveer Yadav Vineeta Singh Source Type: research
Differential protective impact of peptide vaccine formulae targeting the lung- and liver-stage of challenge Schistosoma mansoni infection in mice
Acta Trop. 2024 Apr 14;254:107208. doi: 10.1016/j.actatropica.2024.107208. Online ahead of print.ABSTRACTThe study aimed to elicit protective immune responses against murine schistosomiasis mansoni at the parasite lung- and liver stage. Two peptides showing amino acid sequence similarity to gut cysteine peptidases, which induce strong memory immune effectors in the liver, were combined with a peptide based on S. mansoni thioredoxin peroxidase (TPX), a prominent lung-stage schistosomula excretory-secretory product, and alum as adjuvant. Only one of the 2 cysteine peptidases-based peptides in a multiple antigenic peptide con...
Source: Acta Tropica - April 15, 2024 Category: Infectious Diseases Authors: Hatem Tallima Menerva M Tadros Rashika El Ridi Source Type: research
Differential protective impact of peptide vaccine formulae targeting the lung- and liver-stage of challenge Schistosoma mansoni infection in mice
Acta Trop. 2024 Apr 13:107208. doi: 10.1016/j.actatropica.2024.107208. Online ahead of print.ABSTRACTThe study aimed to elicit protective immune responses against murine schistosomiasis mansoni at the parasite lung- and liver stage. Two peptides showing amino acid sequence similarity to gut cysteine peptidases, which induce strong memory immune effectors in the liver, were combined with a peptide based on S. mansoni thioredoxin peroxidase (TPX), a prominent lung-stage schistosomula excretory-secretory product, and alum as adjuvant. Only one of the 2 cysteine peptidases-based peptides in a multiple antigenic peptide constru...
Source: Acta Tropica - April 15, 2024 Category: Infectious Diseases Authors: Hatem Tallima Menerva M Tadros Rashika El Ridi Source Type: research
Differential protective impact of peptide vaccine formulae targeting the lung- and liver-stage of challenge Schistosoma mansoni infection in mice
Acta Trop. 2024 Apr 13:107208. doi: 10.1016/j.actatropica.2024.107208. Online ahead of print.ABSTRACTThe study aimed to elicit protective immune responses against murine schistosomiasis mansoni at the parasite lung- and liver stage. Two peptides showing amino acid sequence similarity to gut cysteine peptidases, which induce strong memory immune effectors in the liver, were combined with a peptide based on S. mansoni thioredoxin peroxidase (TPX), a prominent lung-stage schistosomula excretory-secretory product, and alum as adjuvant. Only one of the 2 cysteine peptidases-based peptides in a multiple antigenic peptide constru...
Source: Acta Tropica - April 15, 2024 Category: Infectious Diseases Authors: Hatem Tallima Menerva M Tadros Rashika El Ridi Source Type: research
Microbiome Profile of South Korean Vector Mosquitoes
This study sheds light on the complex interactions between mosquitoes and their microbiome, revealing potential implications for vector competence, disease transmission, and vector control strategies.PMID:38608996 | DOI:10.1016/j.actatropica.2024.107213 (Source: Acta Tropica)
Source: Acta Tropica - April 12, 2024 Category: Infectious Diseases Authors: Ashraf Akintayo Akintola Ui Wook Hwang Source Type: research
Microbiome Profile of South Korean Vector Mosquitoes
This study sheds light on the complex interactions between mosquitoes and their microbiome, revealing potential implications for vector competence, disease transmission, and vector control strategies.PMID:38608996 | DOI:10.1016/j.actatropica.2024.107213 (Source: Acta Tropica)
Source: Acta Tropica - April 12, 2024 Category: Infectious Diseases Authors: Ashraf Akintayo Akintola Ui Wook Hwang Source Type: research
Microbiome Profile of South Korean Vector Mosquitoes
This study sheds light on the complex interactions between mosquitoes and their microbiome, revealing potential implications for vector competence, disease transmission, and vector control strategies.PMID:38608996 | DOI:10.1016/j.actatropica.2024.107213 (Source: Acta Tropica)
Source: Acta Tropica - April 12, 2024 Category: Infectious Diseases Authors: Ashraf Akintayo Akintola Ui Wook Hwang Source Type: research
sCD155 as a Potential Marker for Diagnosing the Vascular Invasion in Hepatic Alveolar Echinococcosis
CONCLUSION: The sCD155 could be a VI biomarker for HAE. Elevated sCD155 levels are indicative of an increased likelihood of concomitant VI in HAE patients, necessitating a thorough evaluation of vascular impairment and the formulation of individualized management strategies.PMID:38604326 | DOI:10.1016/j.actatropica.2024.107203 (Source: Acta Tropica)
Source: Acta Tropica - April 11, 2024 Category: Infectious Diseases Authors: Tao Sun Ning Yang Liang Li Xue Zhang Hui Liu Nuerbaiti Kusuman Jin Chu Guodong L ü Tuerganaili Aji Xiaojuan Bi Renyong Lin Source Type: research
An association between PM < sub > 2.5 < /sub > -related components and respiratory infectious diseases: A China's mainland-based study
This study is the first to explore the relationship between different components of PM2.5 and the incidence of five common respiratory infectious diseases in 31 provinces of China, which provides a certain theoretical basis for future research.PMID:38604327 | DOI:10.1016/j.actatropica.2024.107193 (Source: Acta Tropica)
Source: Acta Tropica - April 11, 2024 Category: Infectious Diseases Authors: Donghua Li Tianshan Shi Lei Meng Xiaoshu Zhang Rui Li Tingrong Wang Xin Zhao Hongmiao Zheng Xiaowei Ren Source Type: research
