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This page shows you the latest news items in this category. This is page number 16.

Wayne State research may develop next generation of vaccines against autoimmune diseas
(Wayne State University - Office of the Vice President for Research) A major barrier to treating autoimmune diseases such as Type 1 diabetes is the lack of methods to deliver the therapeutics to specific sites such as the lymph nodes. A researcher in Wayne State University's College of Engineering is working to address this issue with a recently awarded a $475,752 grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 27, 2014 Category: Global & Universal Source Type: news

Gene identified for immune system reset after infection
(Duke University) Duke University researchers have uncovered the genes that are normally activated during recovery from bacterial infection. The finding, from C. elegans worms, could lead to ways to jumpstart this recovery process and possibly fend off autoimmune diseases and chronic inflammatory disorders that can result from the body staying in attack mode for too long. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 23, 2014 Category: Infectious Diseases Source Type: news

T1DM remission with sitagliptin
Type 1 diabetes mellitus (T1DM) is a chronic disease characterized by the autoimmune destruction of pancreatic β-cells in genetically susceptible subjects, which results in absolute insulin deficiency. Several agents used to reestablish immunological tolerance over the past few years have successfully prevented and even reverted T1DM in nonobese diabetic mice; however, these outcomes have not been achieved in humans.   Lima-Martinez et al. report on a case of a 19-year old male on intensive insulin treatment as he presented with glutamic acid decarboxylase (GAD) antibody positive and diabetic ketoacidos...
Source: Society for Endocrinology - October 21, 2014 Category: Endocrinology Source Type: news

Interleukin-27: Can a cytokine with both pro & anti-inflammatory activity make a good drug target?
(Mary Ann Liebert, Inc./Genetic Engineering News) Interleukin-27, a member of the interleukin family of cytokines that help regulate the immune system, has a mainly anti-inflammatory role in the body, and its dysfunction has been implicated in autoimmune diseases such as multiple sclerosis and Crohn's disease. More recently, IL-27's proinflammatory activity and role in chronic inflammatory diseases is becoming increasingly clear, and a new Review article that explores the potential to target a range of diseases that share common IL-27-activated mechanisms is presented in. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 20, 2014 Category: Global & Universal Source Type: news

Blood test helps predict relapse in patients with autoimmune disease affecting the kidneys
Among patients with an autoimmune disease called ANCA-associated vasculitis, autoantibody increases were linked with an 11-fold increased risk of relapse in patients whose kidneys were affected, a study concludes. Among patients without kidney involvement, such increases were associated only weakly with relapses. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 16, 2014 Category: Science Source Type: news

MGH and MIT form strategic partnership to address major challenges in clinical medicine
(Massachusetts General Hospital) A novel partnership between Massachusetts General Hospital and Massachusetts Institute of Technology is addressing three major challenges in clinical medicine -- improving the diagnosis of disease, developing new approaches to prevent and treat infectious and autoimmune diseases, and developing more accurate methods of diagnosing and treating major neurodegenerative and psychiatric diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 15, 2014 Category: Global & Universal Source Type: news

Pattern recognition receptors may be potent new drug targets for immune-mediated diseases
(Mary Ann Liebert, Inc./Genetic Engineering News) Chronic inflammation caused by activation of the human immune system contributes to a large and rapidly growing list of diseases including some cancers, cardiovascular disease, metabolic disorders, and autoimmune diseases. Significant advances in understanding the role that the cytokine-mediated JAK/STAT signaling network and pattern recognition receptors play in regulating immune responses and their potential as novel targets for developing potent new therapies are presented in a Review article in Journal of Interferon & Cytokine Research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 15, 2014 Category: Global & Universal Source Type: news

RheumShorts: Sjogren's Syndrome, Joint Replacement (CME/CE)
(MedPage Today) -- Like other autoimmune diseases, Sjogren's is associated with early cardiovascular changes. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 14, 2014 Category: Cardiology Source Type: news

RheumFocus: Sjogren's Syndrome, Joint Replacement (CME/CE)
(MedPage Today) -- Like other autoimmune diseases, Sjogren's is associated with early cardiovascular changes. (Source: MedPage Today Pain Management)
Source: MedPage Today Pain Management - October 14, 2014 Category: Anesthesiology Source Type: news

Single gene links susceptibility to rare infections with predisposition to autoimmune disease
When scientists scanned the brains of patients who lack a particular immune protein, they saw calcium deposits (center white spots) linked with certain diseases that occur as a result of harmful and unnecessary inflammation. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 12, 2014 Category: Biomedical Science Authors: pubaff Tags: Science News autoimmune disease Dusan Bogunovic interferon ISG15 Jean-Laurent Casanova mycobacteria Source Type: news

Opinion: Can Celiac Disease Affect the Brain?
Some scientists have linked gluten with neurological symptoms. (Source: NYT)
Source: NYT - October 11, 2014 Category: Nutrition Authors: By MOISES VELASQUEZ-MANOFF Tags: Schizophrenia Mental Health and Disorders Autoimmune Diseases Research Autism Brain Celiac Disease Gluten Nerves and Nervous System Immune System Source Type: news

Opinion: Can Celiac Disease Affect the Brain?
Some scientists have linked gluten with neurological symptoms. (Source: NYT Health)
Source: NYT Health - October 11, 2014 Category: Consumer Health News Authors: By MOISES VELASQUEZ-MANOFF Tags: Schizophrenia Mental Health and Disorders Autoimmune Diseases Research Autism Brain Celiac Disease Gluten Nerves and Nervous System Immune System Source Type: news

Is a cure for type 1 diabetes 'within reach'?
Conclusion This is promising early-stage research into the possible generation of insulin-producing pancreatic beta cells from stem cells in a laboratory. The researchers demonstrated that they were able to successfully produce large numbers of functioning stem cell-derived cells that looked structurally similar to normal beta cells and produced insulin in response to glucose in the same way. The successful function of these cells was demonstrated both in the laboratory and when transplanted into mice, including mice genetically engineered to have diabetes. There is currently no "cure" for type 1 diabetes and ...
Source: NHS News Feed - October 10, 2014 Category: Consumer Health News Tags: Diabetes Genetics/stem cells Source Type: news

Fundamental theory about education of immune police questioned by researchers
A fundamental theory about how our thymus educates our immune police appears to be wrong, scientists say. The finding provides more insight into immunity that could one day enable a new approach to vaccines that steer the thymus to produce more of whatever T cell type a patient needs: more effector cells if they have a bad infection or cancer, more regulatory T cells if they are experiencing autoimmune diseases like arthritis and multiple sclerosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 8, 2014 Category: Science Source Type: news

A New Pathway Discovered Regulating Autoimmune Diseases
Molecule delays disease onset and reverses disease progression. (Source: BWH News)
Source: BWH News - October 8, 2014 Category: Hospital Management Source Type: news

A New Pathway Discovered Regulating Autoimmune Diseases
Molecule delays disease onset and reverses disease progression. (Source: BWH for Journalists)
Source: BWH for Journalists - October 7, 2014 Category: Research Source Type: news

Histiocytosis: Symptoms and Treatment Information
Histiocytosis is also referred to as, "Langerhans Cell Histiocytosis (LCH)," or more formally as, "Histiocytosis X," and represents a group of rare disorders involving specific cells that usually have important roles as part of a person's immune system. (Source: Disabled World)
Source: Disabled World - October 7, 2014 Category: Disability Tags: Autoimmune Diseases Source Type: news

Efficacy of potential therapy for autoimmune disorder of muscle weakness
(University of Pennsylvania School of Medicine) Researchers have made a fast-acting 'vaccine' that can reverse the course of myasthenia gravis, a non-inherited autoimmune form of muscle weakness, in an animal model of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 7, 2014 Category: Global & Universal Source Type: news

Pain receptor on T-cells discovered
T-cells -- a type of white blood cell that learns to recognize and attack microbial pathogens -- are activated by a pain receptor, scientists have discovered. The study shows that the receptor helps regulate intestinal inflammation in mice and that its activity can be manipulated, offering a potential new target for treating certain autoimmune disorders, such as Crohn's disease and possibly multiple sclerosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 5, 2014 Category: Science Source Type: news

Viral infection may trigger childhood diabetes in utero
A likely trigger for juvenile diabetes before birth has been identified by researchers who have put forth evidence that the autoimmune disease is initiated in utero. Women who contract a viral infection during pregnancy transmit viruses to their genetically susceptible fetuses, sparking the development of type 1 diabetes, they propose. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 3, 2014 Category: Science Source Type: news

Viral infection may trigger childhood diabetes in utero
(American Friends of Tel Aviv University) A new study from Tel Aviv University suggests a likely trigger for juvenile diabetes before birth. World-renowned TAU researcher professor Zvi Laron has put forth evidence that the autoimmune disease is initiated in utero. Women who contract a viral infection during pregnancy transmit viruses to their genetically susceptible fetuses, sparking the development of type 1 diabetes, he says. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 3, 2014 Category: Global & Universal Source Type: news

Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds
Breast-feeding, waiting to introduce foods with gluten didn't prevent autoimmune disorder (Source: WebMD Health)
Source: WebMD Health - October 1, 2014 Category: Consumer Health News Source Type: news

Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds
Breast-feeding, waiting to introduce foods with gluten didn't prevent autoimmune disorder Source: HealthDay Related MedlinePlus Pages: Breastfeeding, Celiac Disease, Infant and Newborn Nutrition (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 1, 2014 Category: Consumer Health News Source Type: news

The Dance Between The Immune System and Stem Cells
We named it the  immunoLinkTM We have been testing a growing number of Clients with our Quantibody Arrays. Many of of these clients have Autoimmune Disorder Diseases. These range from Rheumatoid Arthritis to Multiple Sclerosis.These arrays are designed to precisely measure factors or markers (proteins) that are dysregulated by these diseases. We measure the levels of these biomarkers in our Clients' Blood serum. The arrays have also been used to measure the levels of markers in plasma and cell culture supernatants.Based on results, we are finding links between immune system and stem cell health. We call this the ...
Source: Neuromics - September 30, 2014 Category: Neuroscience Tags: autoimmune disease G-CSF GM-CSF Human Mesenchymal Stem Cells immune response immunoLink Neural Progenitor Cells Neural Stem Cell Markers Source Type: news

Protecting the body from itself: How defense cells fight disease, but not themselves
A clearer relationship between two cells that serve our body's natural defense mechanisms against diseases and infections has now been gained through new research. The findings will help the medical community better understand autoimmunity and could pave the way for treatment of autoimmune diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 26, 2014 Category: Science Source Type: news

Discovery may lead to better treatments for autoimmune diseases, bone loss
Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 25, 2014 Category: Science Source Type: news

Autoimmune diseases, chronic inflammations: Advancing research
Multiple sclerosis, type 1 diabetes and lupus are autoimmune diseases in which the immune cells can no longer differentiate between friend and foe and thus attack the body's own tissue. Here, the immunoproteasome, which supplies the immune system with information on processes within the cell, plays a central role. Chemists have now discovered a way to inhibit its functionality, thereby laying the foundation for possible optimizations of existing medications. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 25, 2014 Category: Science Source Type: news

Spot on against autoimmune diseases and chronic inflammations
(Technische Universitaet Muenchen) Multiple sclerosis, type 1 diabetes and lupus are autoimmune diseases in which the immune cells can no longer differentiate between friend and foe and thus attack the body's own tissue. Here, the immunoproteasome, which supplies the immune system with information on processes within the cell, plays a central role. Chemists at Technische Universität München have now discovered a way to inhibit its functionality, thereby laying the foundation for possible optimizations of existing medications. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 25, 2014 Category: Biology Source Type: news

Protecting the body from itself
(Biomedical Sciences Institutes (BMSI)) Scientists from A*STAR's Bioprocessing Technology Institute have established a clearer relationship between two cells which serve our body's natural defense mechanisms against diseases and infections. Their findings, published in the prestigious journal Cell Reports, will help the medical community better understand autoimmunity and could pave the way for treatment of autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2014 Category: Global & Universal Source Type: news

Findings give hope to plant extract as possible lupus treatment
(University of Houston) Lupus is a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. New findings by a biomedical engineer and his team at the University of Houston raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments for this disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 24, 2014 Category: Global & Universal Source Type: news

Math model designed to replace invasive kidney biopsy for lupus patients
Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. The model could also be used to monitor the effectiveness of experimental treatments for inflammation and fibrosis, researchers say. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 17, 2014 Category: Science Source Type: news

Math model designed to replace invasive kidney biopsy for lupus patients
(Ohio State University) Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2014 Category: Global & Universal Source Type: news

Autoimmune Diseases Tied to Eating Disorders
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 16, 2014 Category: Journals (General) Source Type: news

Autoimmune Diseases Tied to Eating Disorders
Several autoimmune diseases have been linked to, and may even play a role in the development of, eating disorders, new research suggests. (Source: WebMD Health)
Source: WebMD Health - September 12, 2014 Category: Consumer Health News Source Type: news

Brain inflammation dramatically disrupts memory retrieval networks, study finds
Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to scientists. The study specifically identifies how immune system signaling molecules, called cytokines, impair communication among neurons in the hippocampus, an area of the brain critical for discrimination memory. The findings offer insight into why cognitive deficits occurs in people undergoing chemotherapy and those with autoimmune or neurodegenerative diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 12, 2014 Category: Science Source Type: news

Cytokines and Neuropathic Pain
I have been frequently posting results of testing blood serum of our clients suffering from Autoimmune (including Neuroimmuno) Diseases and Autistic Children. Our testing includes both standard medical testing (serum levels of toxins, metals, pathogen loads and markers like Cortisol, CRP, CDs, ALPS, NSE, S100b). In addition, we also doing testing using our Quantibody® Antibody.Many of the clients report chronic mild to severe neuropathic pain.By definition, this pain encompasses a series of heterogeneous conditions with some similar clinical manifestations. Peripheral examples include traumatic nerve injury, diabetic peri...
Source: Neuromics - September 10, 2014 Category: Neuroscience Tags: chronic pain Cytokine Antibody Arrays Diabetic Neuropathy Inflammatory pain inflammatory response Interleukins neuroinflammatory cytokines Neuropathic Pain Source Type: news

How skin falls apart: Pathology of autoimmune skin disease revealed at the nanoscale
Researchers studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin. The research has the potential to help clinicians identify who may be at risk for developing Pemphigus vulgaris (PV), an autoimmune skin disorder, by distinguishing pathogenic (disease-causing) autoimmune antibodies from other nonpathogenic autoimmune antibodies. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 10, 2014 Category: Science Source Type: news

Jim Sullivan on Improving the Lives of Patients
At AbbVie, research and innovation are the cornerstones of our business as a global biopharmaceutical company. We focus on developing medicines that deliver strong clinical performance, provide more patient benefit and deliver economic value, particularly where there is significant need around the world in certain disease areas.  Arthritis is an example of a disease where we have the opportunity to continue to make headway to improve the lives of patients. According to the U.S. Centers for Disease Control and Prevention (CDC) prevalence of musculoskeletal diseases could increase from 52 million people in the U.S. to 67 mi...
Source: PHRMA - September 9, 2014 Category: Pharmaceuticals Authors: Emily Source Type: news

VTE Risk High in Autoimmune Muscle Disease
(MedPage Today) -- Patients with the inflammatory myopathies polymyositis and dermatomyositis had markedly elevated risks for venous thromboembolic events, a population-based study in Canada found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 9, 2014 Category: Cardiology Source Type: news

Autoimmune Diseases Implicated in Eating DisordersAutoimmune Diseases Implicated in Eating Disorders
Autoimmune diseases are associated with, and may even play a role in the development of, eating disorders. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - September 8, 2014 Category: Psychiatry Tags: Dermatology News Source Type: news

How immunotherapy may treat multiple sclerosis
Conclusion This mouse study using a mouse model of MS has found that the dose-escalation protocol is extremely important for inducing tolerance, in this case a small fragment of myelin basic protein. Escalation dose immunotherapy minimised immune system activation and proliferation during the early stages, and caused changes in gene expression that caused the attacking immune cells to express regulatory genes and to become suppressive. The researchers hope that some of the changes in immune cells and in gene expression that they have identified can be used in clinical studies of tolerance-inducing treatments for autoimmun...
Source: NHS News Feed - September 4, 2014 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Source Type: news

Breakthrough hope for MS treatment
Scientists say they have discovered how to “switch off” autoimmune diseases such as multiple sclerosis. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - September 4, 2014 Category: Nursing Source Type: news

Multiple sclerosis could be 'switched off' by retraining immune system
Scientists believe they are close to developing a drug which could 'switch off' autoimmune diseases like Multiple sclerosis by training the body to stop attacking itself (Source: Telegraph Health)
Source: Telegraph Health - September 3, 2014 Category: Consumer Health News Source Type: news

Multiple Sclerosis could be 'switched off' by retraining immune system
Scientists believe they are close to developing a drug which could 'switch off' autoimmune diseases like Multiple Sclerosis by training the body to stop attacking itself (Source: Telegraph Health)
Source: Telegraph Health - September 3, 2014 Category: Consumer Health News Source Type: news

Breakthrough hope for MS treatment as scientists discover how to 'switch off' autoimmune diseases 
Researchers at the University of Bristol have found a way of stopping cells from attacking healthy body tissue, and it is hoped the insight will pave the way for new treatments. (Source: the Mail online | Health)
Source: the Mail online | Health - September 3, 2014 Category: Consumer Health News Source Type: news

Scientists discover how to 'switch off' autoimmune diseases
Scientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. Rather than the body's immune system destroying its own tissue by mistake, researchers have discovered how cells convert from being aggressive to actually protecting against disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 3, 2014 Category: Science Source Type: news

Scientists discover how to ‘switch off’ autoimmune diseases
Scientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. (Source: University of Bristol news)
Source: University of Bristol news - September 3, 2014 Category: Universities & Medical Training Tags: Research; Faculty of Medical and Veterinary Sciences, Faculty of Medical and Veterinary Sciences, School of Cellular and Molecular Medicine, Faculty of Engineering, Faculty of Engineering, Merchant Venturers' School of Engineering, Computer Science, Facul Source Type: news

Systemic effects of intratympanic steroids
Intratympanic glucocorticoids are effective in the treatment of sudden sensorineural hearing loss, the stabilization of Ménière's disease, and in autoimmune ear disorders. Intratympanic administration should minimise systemic side effects. Novoa and colleagues carried out a prospective cohort study, finding that intratympanic dexamethason did not interfere with endogenous cortisol secretion or bone metabolism. Read the full article at Novoa et al. (2014) Endocrine Connections 3 127–131; DOI:10.1530/EC-14-0076 (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 29, 2014 Category: Endocrinology Source Type: news

Hyperthyroidism, Hypothyroidism, and Screening in PregnancyHyperthyroidism, Hypothyroidism, and Screening in Pregnancy
Should pregnant women with autoimmune thyroid disease receive levothyroxoine? What are the risks and benefits? Endocrine Practice (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 29, 2014 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

CU scientists' discovery could lead to new cancer treatment
(The Bawmann Group) A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients. These findings could have implications that extend beyond cancer, including treatments for inborn immunodeficiency and metabolic conditions and autoimmune diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 29, 2014 Category: Cancer & Oncology Source Type: news