What Is the Survival Rate for Ependymoma?
Title: What Is the Survival Rate for Ependymoma?Category: Diseases and ConditionsCreated: 4/20/2022 12:00:00 AMLast Editorial Review: 4/20/2022 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - April 20, 2022 Category: Cancer & Oncology Source Type: news
Heart drug could increase survival rates for children with aggressive form of brain tumor
(University of Nottingham) Researchers at the University of Nottingham have discovered that repurposing a heart drug could significantly increase the survival rate for children with ependymoma - a type of brain tumour. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2019 Category: International Medicine & Public Health Source Type: news
Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins
Neurofibromatosis type 2 is an inherited, neoplastic disease associated with schwannomas, meningiomas, and ependymomas and that is caused by inactivation of the tumor suppressor gene NF2. The NF2 gene product, Merlin, has no intrinsic catalytic activity; its tumor suppressor function is mediated through the proteins with which it interacts. We used proximity biotinylation followed by mass spectrometry and direct binding assays to identify proteins that associated with wild-type and various mutant forms of Merlin in immortalized Schwann cells. We defined a set of 52 proteins in close proximity to wild-type Merlin. Most of t...
Source: Signal Transduction Knowledge Environment - April 22, 2019 Category: Science Authors: Hennigan, R. F., Fletcher, J. S., Guard, S., Ratner, N. Tags: STKE Research Resources Source Type: news
Radiation after surgery triples survival for a type of pediatric brain tumor
(St. Jude Children's Research Hospital) Radiation immediately following surgery in children with ependymoma, the third most common pediatric brain tumor, can nearly triple survival. The Phase II clinical trial was sponsored by COG, the world's largest cooperative pediatric cancer research organization. This was the first cooperative group study to give immediate postoperative radiation to children under age 3 with ependymoma. The clinical trial was open at more than 100 locations and enrolled nearly 400 patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2019 Category: International Medicine & Public Health Source Type: news
High-resolution genomic map gives scientists unprecedented view of brain development
(St. Jude Children's Research Hospital) The research will not only aid basic understanding of brain development, but also provide a foundation for understanding the cellular origins of brain disorders caused by errors in development. These anatomical defects include Joubert syndrome, Dandy-Walker malformation and pontocerebellar hypoplasia. The database will enable future studies tracing the cellular origins of childhood brain tumors such as medulloblastoma, astrocytoma and ependymoma.Researchers worldwide can interact with the data via an interface St. Jude has created called Cell Seek. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 13, 2018 Category: Biology Source Type: news
Childhood Ependymoma Brain Cancer
Childhood Ependymoma (Brain Cancer) (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 4, 2018 Category: General Medicine Source Type: news
Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype
(University of Colorado Anschutz Medical Campus) A University of Colorado Cancer Center study published in the journal Pediatric Blood Cancers lays the scientific groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 29, 2018 Category: Cancer & Oncology Source Type: news
Molecular super enhancers: A new key for targeted therapy of brain cancer in children
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Ependymoma refers to a heterogeneous group of cancers that can occur at any age and is one of the most common types of brain cancer in children. The genetic causes for its development are largely unknown and there are no targeted treatments to date. Scientists from the Hopp Children's Cancer Center at the NCT Heidelberg, in collaboration with colleagues from the US and Canada, have now developed a molecular approach that opens new treatment prospects. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 20, 2017 Category: Cancer & Oncology Source Type: news
Medical News Today: Ependymoma: Symptoms and treatment
Ependymoma is a tumor of the brain and spinal cord that is more common in children than adults. An ependymoma tumor may contain cysts and can be removed. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 7, 2017 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
NovoCure launches 2 pediatric trials of TTFields
NovoCure (NSDQ:NVCR) said today it is launching 2 pilot trials exploring the use of tumor treating fields to treat pediatric patients with high grade gliomas.
The St. Helier, N.J.-based company produces the Optune, a mobile device that delivers low-intensity, intermediate frequency, alternating electric fields, referred to as “tumor treating fields” to inhibit cancer cell replication and cause cancer cell death.
The 1st trial is being sponsored by the Pediatric Brain Tumor Consortium in collaboration with the National Cancer Institute and will study the feasibility of using TTFields on children with recurrent or...
Source: Mass Device - May 4, 2017 Category: Medical Equipment Authors: Fink Densford Tags: Clinical Trials Oncology NovoCure Source Type: news
Going beyond genetics yields clues to challenging childhood brain cancer
Changes in the epigenetics suggest a prognostic marker for childhood ependymomas and similarities with DIPG tumors, report scientists. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 23, 2016 Category: Science Source Type: news
Radiation in Children With Ependymoma Improves Outcomes Radiation in Children With Ependymoma Improves Outcomes
The largest trial in this rare type of brain tumor has shown that radiotherapy after surgery improves outcomes compared with what has been seen historically. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 20, 2015 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Spinal Ependymomas. Part 2: Filum Terminale EpendymomasSpinal Ependymomas. Part 2: Filum Terminale Ependymomas
Extramedullary ependymomas are slow-growing tumors in the lumbosacral region, often growing to an enormous size. What are the treatment options? Neurosurgical Focus (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 4, 2015 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Targeted Radiotherapy Boost Helps Ependymoma Outcome in KidsTargeted Radiotherapy Boost Helps Ependymoma Outcome in Kids
Children with ependymoma and residual disease after initial surgery and radiotherapy can benefit both from further surgery and an extra boost of radiotherapy. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 28, 2015 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
High radiotherapy dose improves prospects for children with brain cancer
Researchers have found that increasing the dose of radiotherapy given to children with an intracranial ependymoma, a form of cancer of the central nervous system, can significantly improve their survival. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 26, 2015 Category: Science Source Type: news
