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The microbiota as instructor and arbiter of immune responses in health and disease
NIH Director's Wednesday Afternoon Lecture Series Dr. Littman ’ s laboratory applies molecular and genetics tools to study how T lymphocytes develop and participate in inflammation and how HIV interacts with the host innate immune system. Dr. Littman isolated the genes for the CD4 and CD8 co-receptors and determined how their expression is regulated and their signaling influences selection of helper and cytotoxic cells. His group discovered that the nuclear receptor ROR  t regulates differentiation of Th17 cells and lymphoid tissue inducer cells and that it can be targeted for autoimmune disease therapy. He and his co...
Source: Videocast - All Events - February 6, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Leonard H. Calabrese, DO - Recent Advances in the Management of Rheumatoid Arthritis: A Clinical Update From Washington, DC
Recent Advances in the Management of Rheumatoid Arthritis: A Clinical Update From Washington, DC (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - December 30, 2016 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Cytokine Signaling: Genes, Genomes and Drugs
Eleventh annual Philip S. Chen, Jr., Ph.D. Distinguished Lecture on Innovation and Technology Transfer John J. O'Shea graduated Phi Beta Kappa from St. Lawrence University with a Bachelor of Science degree, and then gained a Doctor of Medicine degree from the University of Cincinnati. He carried out a residency in Internal Medicine at the State University of New York Upstate Medical University and did subspecialty training at the National Institute of Allergy and Infectious Diseases, NIH. Dr. O ’ Shea has made fundamental discoveries related to the basic mechanisms underlying cytokine signal transduction, molecule...
Source: Videocast - All Events - October 4, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

The Role of PTPN22 in Autoimmunity and Viral Immunity.
Dr. Linda Sherman received her Ph.D. from M.I.T. in Biology, and did postdoctoral research in immunology at Albert Einstein Medical College and Harvard Medical School, after which she started her laboratory at The Scripps Research Institute, where she remained throughout her career. She has served on advisory panels for the National Science Foundation, The American Cancer Society, The Juvenile Diabetes Foundation, and The National Institutes of Health. She was a member of the Advisory Council to the National Institute of Diabetes and Digestive and Kidney Disease from 2002-2006. She has served on numerous committees for the...
Source: Videocast - All Events - March 24, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

Sequencing the Functional Antibody Repertoire in Rheumatoid Arthritis
Presented by: Dr. Bill Robinson, Associate Professor, Stanford UniversityCategory: HHS OnlyAired date: 11/30/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - December 2, 2015 Category: Journals (General) Tags: Past Events Source Type: video

Sequencing the Functional Antibody Repertoire in Rheumatoid Arthritis
CHI lecture Air date: 11/30/2015 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 23, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

NIH Research Festival: A Celebration of Intramural Science Plenary Session III: Chronic Inflammation
Most of the NIH institutes and centers are involved in studies for which chronic inflammation is a common denominator. Allergies, asthma, heart and circulatory disease, rheumatoid arthritis, inflammatory bowel disease, celiac disease, some cancers, multiple sclerosis, and possibly Alzheimer’s. These are just a few debilitating diseases that can originate partly or entirely from the immune system’s aggressive response to perceived harmful stimuli. Aging itself has been described as the totality of a lifetime of chronic inflammation. Better understanding the causes and control of chronic inflammation thus can lead to pro...
Source: Videocast - All Events - September 15, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Neutrophils in the pathogenesis of systemic autoimmune diseases: casting the NET widely
NIH Director's Seminar Series Systemic autoimmune diseases comprise a clinically heterogeneous group of disorders characterized by a failure in self-tolerance to a wide variety of intracellular autoantigens, and include conditions like systemic lupus erythematosus, rheumatoid arthritis and anti-neutrophil cytoplasmic antibody associated-vasculitis. Work at the Systemic Autoimmunity Branch has focused on characterizing the role that aberrant neutrophils play in the promotion of loss of immunological tolerance, amplification of inflammatory responses and direct end-organ damage in these diseases. One characteristic of ne...
Source: Videocast - All Events - May 4, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Jeffrey R. Curtis, MD, MS, MPH - Optimizing the Clinical Use of Biologics in Rheumatoid Arthritis: A Case-Based Approach to the Assessment of Disease Activity and Response to Therapy
Optimizing the Clinical Use of Biologics in Rheumatoid Arthritis: A Case-Based Approach to the Assessment of Disease Activity and Response to Therapy (Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - October 31, 2014 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Joel M. Kremer, MD - Expert Perspectives in Rheumatoid Arthritis: Examining the Practical Implications of Updated Guidelines
(Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - October 11, 2013 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Rheumatoid Arthritis: Katy’s Journey
Katy was diagnosed with rheumatoid arthritis in 2010. Since then she has gone on to live a very active lifestyle and has not let her condition stop her from doing anything. This is her inspiring story. (Source: Streaming Well - Health Videos)
Source: Streaming Well - Health Videos - June 19, 2013 Category: Consumer Health Advice Source Type: video