The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):545-546. doi: 10.7326/L24-0004.NO ABSTRACTPMID:38621265 | DOI:10.7326/L24-0004 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kavita Narula Katharine Lazarus Sirazum Choudhury Karim Meeran Source Type: research

The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):545. doi: 10.7326/L24-0003.NO ABSTRACTPMID:38621264 | DOI:10.7326/L24-0003 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Daniel Arkfeld Sofia Audrey B Gonzales Katherine Ruddy Source Type: research

Rheumatology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0678. Online ahead of print.ABSTRACTMany patients with rheumatologic conditions receive care from physicians other than rheumatologists. Here we note key findings from 6 studies in rheumatology published in 2023 that offer valuable insights for internal medicine specialists and subspecialists outside of rheumatology. The first study investigated the effect of low-dose glucocorticoids on patients with rheumatoid arthritis (RA) over 2 years and challenged existing perceptions about the risks of glucocorticoids in this setting. The second study focused on the updated guideline for...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kafaf Jalali Lisa A Mandl Source Type: research

When Should I Get My Next COVID Vaccine? Data from the SUrveillance of responses to COVID-19 vaCcines in systEmic immunE mediated inflammatory Diseases (SUCCEED)study
CONCLUSION: Ours is the first pan-Canadian IMID assessment of how vaccine history and other factors affect serologic COVID-19 vaccine responses. These findings may help individuals personalize vaccination decisions, including consideration of additional vaccination when >6 months has elapsed since last COVID vaccination/infection.PMID:38621797 | DOI:10.3899/jrheum.2023-1214 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Dawn M E Bowdish Vinod Chandran Carol A Hitchon Gilaad G Kaplan J Antonio Avina-Zubieta Paul R Fortin Maggie J Larch é Gilles Boire Anne-Claude Gingras Roya M Dayam Ines Colmegna Luck Lukusa Jennifer L F Lee Dawn P Richards Daniel Pereira Tania H Watts M Source Type: research

Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research

Sensors, Vol. 24, Pages 2526: Design of a Self-Measuring Device Based on Bioelectrical Impedance Analysis for Regular Monitoring of Rheumatoid Arthritis
This study underscores the significance of considering patients’ disease activity during intervals between hospital visits and introduces a novel approach to self-RA care. (Source: Sensors)
Source: Sensors - April 15, 2024 Category: Biotechnology Authors: JuYoung Jeong Yun Soo Park Eunchae Lee SeoYoun Choi Dokshin Lim Jiho Kim Tags: Article Source Type: research

Associations of per- and polyfluoroalkyl substances (PFAS) and their mixture with risk of rheumatoid arthritis in the U.S. adult population
Per- and polyfluoroalkyl substances (PFAS) are known environmental contaminants with immunosuppressive properties. Their connection to rheumatoid arthritis (RA), a condition influenced by the immune system, is... (Source: Environmental Health)
Source: Environmental Health - April 13, 2024 Category: Environmental Health Authors: Jian-Chao Qiao, Zhen-Hua Li, Yu-Bo Ma, Hui-Ya Ma, Meng-Yue Zhang, Xiu-Jun Zhang and Cheng-Yang Hu Tags: Research Source Type: research

Tofacitinib and Peficitinib inhibitors of Janus kinase for autoimmune diseases treatments: A Quantum Biochemistry Description
Phys. Chem. Chem. Phys., 2024, Accepted Manuscript DOI: 10.1039/D3CP06332A, PaperJackson Lima Amaral, Naiara Lucredi, Victor L. B. Fran ça, Samuel J. M. Santos, Francisco F. Maia, Pablo A. Morais, Pedro F. N. Souza, Jurandir F. Comar, Valder N. Freire Autoimmune inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis are associated with uncontrolled production of cytokines leading to the pronounced inflammatory response of these disorders. The therapy is... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Phys. Chem. Chem. Phys. latest articles)
Source: RSC - Phys. Chem. Chem. Phys. latest articles - April 12, 2024 Category: Chemistry Authors: Jackson Lima Amaral Source Type: research

Satellite Glial Cells in Human Disease
Cells. 2024 Mar 23;13(7):566. doi: 10.3390/cells13070566.ABSTRACTSatellite glial cells (SGCs) are the main type of glial cells in sensory ganglia. Animal studies have shown that these cells play essential roles in both normal and disease states. In a large number of pain models, SGCs were activated and contributed to the pain behavior. Much less is known about SGCs in humans, but there is emerging recognition that SGCs in humans are altered in a variety of clinical states. The available data show that human SGCs share some essential features with SGCs in rodents, but many differences do exist. SGCs in DRG from patients suf...
Source: Herpes - April 12, 2024 Category: Infectious Diseases Authors: Menachem Hanani Source Type: research

Association between Life's Essential 8 and all-cause or cardiovascular-specific mortality in patients with rheumatoid arthritis
CONCLUSIONS: CVH measured by the LE8 score is a robust and independent predictor of all-cause mortality among U.S. RA patients.PMID:38607691 | DOI:10.55563/clinexprheumatol/ppsp71 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 12, 2024 Category: Rheumatology Authors: Xiufang Kong Wei Wang Source Type: research

Satellite Glial Cells in Human Disease
Cells. 2024 Mar 23;13(7):566. doi: 10.3390/cells13070566.ABSTRACTSatellite glial cells (SGCs) are the main type of glial cells in sensory ganglia. Animal studies have shown that these cells play essential roles in both normal and disease states. In a large number of pain models, SGCs were activated and contributed to the pain behavior. Much less is known about SGCs in humans, but there is emerging recognition that SGCs in humans are altered in a variety of clinical states. The available data show that human SGCs share some essential features with SGCs in rodents, but many differences do exist. SGCs in DRG from patients suf...
Source: Herpes - April 12, 2024 Category: Infectious Diseases Authors: Menachem Hanani Source Type: research

Association between Life's Essential 8 and all-cause or cardiovascular-specific mortality in patients with rheumatoid arthritis
CONCLUSIONS: CVH measured by the LE8 score is a robust and independent predictor of all-cause mortality among U.S. RA patients.PMID:38607691 | DOI:10.55563/clinexprheumatol/ppsp71 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 12, 2024 Category: Rheumatology Authors: Xiufang Kong Wei Wang Source Type: research

New | phs003417.v2.p1 | The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis
​ The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis  (study page |release notes) (Source: dbGaP, the database of Genotypes and Phenotypes)
Source: dbGaP, the database of Genotypes and Phenotypes - April 11, 2024 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research