Breast adiposity: Menopausal status impact and its influence on glycemic and anthropometric metabolic parameters
CONCLUSION: The BA was related to different adverse body composition and metabolic factors in women in postmenopause. The results suggest that there might be a relevant BrAT endocrine role during menopause, whose mechanisms are yet to be clarified, which thus opens up research perspectives on the subject as well as on clinical settings.PMID:38558168 | DOI:10.1210/clinem/dgae205 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 1, 2024 Category: Endocrinology Authors: Barbara Limberger Nedel Michelle Garcia Madure Silvia Guaresi Maria Elisa Soares Machado Marcelo Madrid de Bittencourt Nathalia Nobrega Chagas Fernando Gerchman Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Melatonin-mediated corrective changes in gut microbiota of experimentally chronodisrupted C57BL/6J mice
Chronobiol Int. 2024 Apr 1:1-13. doi: 10.1080/07420528.2024.2329205. Online ahead of print.ABSTRACTChronic consumption of a high-calorie diet coupled with an altered sleep-wake cycle causes disruption of circadian clock that can impact the gut microbiome leading to metabolic syndrome and associated diseases. Herein, we investigate the effects of a high fat high fructose diet (H) alone or in combination with photoperiodic shifts induced chronodisruption (CD) on gut microbiota of C57BL/6J male mice. Further, the merits of daily evening intraperitoneal administration of melatonin in restoring gut microbiota are studied herein...
Source: Chronobiology International - April 1, 2024 Category: Biology Authors: Aliasgar Vohra Rhydham Karnik Mansi Desai Hitarthi Vyas Shruti Kulshrestha Kapil Kumar Upadhyay Prakash Koringa Ranjitsinh Devkar Source Type: research

High systemic inflammation as a novel cardiovascular risk factor and target for anti-cytokine therapy: comment regarding the triglyceride glucose index
Int J Cardiovasc Imaging. 2024 Apr 1. doi: 10.1007/s10554-024-03046-6. Online ahead of print.ABSTRACTIn the last century, there has been more than enough research that proved the association of high lipid and glucose levels with cardiovascular disease, thus establishing the current well-known traditional cardiovascular risk factors such as dyslipidemia, diabetes, and metabolic syndrome. Hence, these cardiovascular risk factors are target therapy for glucose and lipid-lowering agents to prevent adverse cardiovascular events. However, despite controlling the lipid and glucose levels, some studies demonstrated the subclinical...
Source: Atherosclerosis - April 1, 2024 Category: Cardiology Authors: Artemio Garc ía-Escobar Rosa L ázaro-García Jos é-Ángel Cabrera Alfonso Jurado-Rom án Ra úl Moreno Source Type: research

Intra-pancreatic fat deposition and its relation to obesity: a magnetic resonance imaging study
CONCLUSIONS: Pancreatic fat content was increased in obese individuals compared with lean controls and predominantly correlated with the amount of visceral adipose tissue. Pancreatic fat content was not clearly linked to measures of pancreatic fibrosis.PMID:38557425 | DOI:10.1080/00365521.2024.2333365 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - April 1, 2024 Category: Gastroenterology Authors: Mimoza Gjela Anders Askeland Maiken Mellergaard Asbj ørn Mohr Drewes Aase Handberg Jens Br øndum Frøkjær Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Melatonin-mediated corrective changes in gut microbiota of experimentally chronodisrupted C57BL/6J mice
Chronobiol Int. 2024 Apr 1:1-13. doi: 10.1080/07420528.2024.2329205. Online ahead of print.ABSTRACTChronic consumption of a high-calorie diet coupled with an altered sleep-wake cycle causes disruption of circadian clock that can impact the gut microbiome leading to metabolic syndrome and associated diseases. Herein, we investigate the effects of a high fat high fructose diet (H) alone or in combination with photoperiodic shifts induced chronodisruption (CD) on gut microbiota of C57BL/6J male mice. Further, the merits of daily evening intraperitoneal administration of melatonin in restoring gut microbiota are studied herein...
Source: Chronobiology International - April 1, 2024 Category: Biology Authors: Aliasgar Vohra Rhydham Karnik Mansi Desai Hitarthi Vyas Shruti Kulshrestha Kapil Kumar Upadhyay Prakash Koringa Ranjitsinh Devkar Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Melatonin-mediated corrective changes in gut microbiota of experimentally chronodisrupted C57BL/6J mice
Chronobiol Int. 2024 Apr 1:1-13. doi: 10.1080/07420528.2024.2329205. Online ahead of print.ABSTRACTChronic consumption of a high-calorie diet coupled with an altered sleep-wake cycle causes disruption of circadian clock that can impact the gut microbiome leading to metabolic syndrome and associated diseases. Herein, we investigate the effects of a high fat high fructose diet (H) alone or in combination with photoperiodic shifts induced chronodisruption (CD) on gut microbiota of C57BL/6J male mice. Further, the merits of daily evening intraperitoneal administration of melatonin in restoring gut microbiota are studied herein...
Source: Chronobiology International - April 1, 2024 Category: Biology Authors: Aliasgar Vohra Rhydham Karnik Mansi Desai Hitarthi Vyas Shruti Kulshrestha Kapil Kumar Upadhyay Prakash Koringa Ranjitsinh Devkar Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Intra-pancreatic fat deposition and its relation to obesity: a magnetic resonance imaging study
CONCLUSIONS: Pancreatic fat content was increased in obese individuals compared with lean controls and predominantly correlated with the amount of visceral adipose tissue. Pancreatic fat content was not clearly linked to measures of pancreatic fibrosis.PMID:38557425 | DOI:10.1080/00365521.2024.2333365 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - April 1, 2024 Category: Gastroenterology Authors: Mimoza Gjela Anders Askeland Maiken Mellergaard Asbj ørn Mohr Drewes Aase Handberg Jens Br øndum Frøkjær Source Type: research

A Review: Cytochrome P450 in Alcoholic and Non-Alcoholic Fatty Liver Disease
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 1, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research