A Non-Inferiority Study on Endometrial Preparation Prior to FET-Letrozole Versus Hormone Replacement Therapy
ConclusionLetrozole FET could be a better alternative to the conventional HRT cycles, in selected population of patients, in terms of reproductive outcomes and patient satisfaction. (Source: The Journal of Obstetrics and Gynecology of India)
Source: The Journal of Obstetrics and Gynecology of India - February 6, 2024 Category: OBGYN Source Type: research

Risks and benefits of hormone replacement therapy in reproductive age women after hematopoietic stem cell transplants: a narrative review
Introduction and aims of the study: Haematopoietic stem cell transplantation increases survival for hematologic malignancies, but increasing numbers of survivors struggle with the side effects. For women with established primary ovarian failure, the question of whether menopausal or contraceptive hormone treatments are more beneficial remains unanswered because no comparative studies have been conducted. The aim of this study was to summarise the main benefits and risks of menopausal hormone therapy for patients who have undergone haematopoietic stem cell transplantation. (Source: European Journal of Obstetrics, Gynecology...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: El żbieta Bumbul-Mazurek, Zana Bumbuliene, Gabija Raziunaite Source Type: research

Endometrial transcriptome profiling of patients with recurrent implantation failure during hormone replacement therapy cycles
ConclusionOur study shows that ER-related genes share similar gene expression patterns during WOI in both natural and HRT cycles, and their aberrant expression is associated with WOI displacements. The improvement of pregnancy outcomes in RIF patients by adjusting ET timing according to ERD results demonstrates the importance of transcriptome-based endometrial receptivity assessment and the clinical efficiency of ERD model. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - January 30, 2024 Category: Endocrinology Source Type: research

Morning exercise affects the absorption of oral levothyroxine: a single center pilot study
ConclusionsThis is the first study which demonstrates the significant positive effect of morning exercise on the absorption of LT4 tablets. In addition to that, it was also found that as the daily dose of LT4 increases, the percentage decrease of TSH level becomes greater. (Source: Endocrine)
Source: Endocrine - January 27, 2024 Category: Endocrinology Source Type: research

Special features on insulin resistance, metabolic syndrome and vascular complications in hypopituitary patients
Rev Endocr Metab Disord. 2024 Jan 25. doi: 10.1007/s11154-023-09872-8. Online ahead of print.ABSTRACTPituitary hormone deficiency, hypopituitarism, is a dysfunction resulting from numerous etiologies, which can be complete or partial, and is therefore heterogeneous. This heterogeneity makes it difficult to interpret the results of scientific studies with these patients.Adequate treatment of etiologies and up-to-date hormone replacement have improved morbidity and mortality rates in patients with hypopituitarism. As GH replacement is not performed in a reasonable proportion of patients, especially in some countries, it is e...
Source: ENDOCR REV - January 25, 2024 Category: Endocrinology Authors: Heraldo M Garmes Source Type: research

Special features on insulin resistance, metabolic syndrome and vascular complications in hypopituitary patients
AbstractPituitary hormone deficiency, hypopituitarism, is a dysfunction resulting from numerous etiologies, which can be complete or partial, and is therefore heterogeneous. This heterogeneity makes it difficult to interpret the results of scientific studies with these patients.Adequate treatment of etiologies and up-to-date hormone replacement have improved morbidity and mortality rates in patients with hypopituitarism. As GH replacement is not performed in a reasonable proportion of patients, especially in some countries, it is essential to understand the known consequences of GH replacement in each subgroup of patients ...
Source: Reviews in Endocrine and Metabolic Disorders - January 25, 2024 Category: Endocrinology Source Type: research