Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Diagnosis and management of congenital hypopituitarism in children
This article presents recommendations for hormone replacement therapy for each of the respective deficient axes. Lifelong follow-up with an endocrinologist is required, including in adulthood, with multidisciplinary management for patients with syndromic forms or comorbidities. Treatment objectives include alleviating symptoms, preventing comorbidities and acute complications, and optimal social and educational integration.PMID:38538470 | DOI:10.1016/j.arcped.2024.01.003 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 27, 2024 Category: Pediatrics Authors: Sarah Castets C écile Thomas-Teinturier Carine Villanueva Jessica Amsellem Pascal Barat Gilles Brun Emmanuel Bui Quoc Jean-Claude Carel Gian Paolo De Filippo Clara Kipnis Laetitia Martinerie Julia Vergier Alexandru Saveanu Natacha Teissier R égis Coutan Source Type: research

Factors associated with low bone mineral density in Turner syndrome: a multicenter prospective observational study
In conclusion, the present study found no relationship between the vertebral BMAD Z-score and diet or exercise habits in TS, indicating that estrogen deficiency is the chief reason for low BMD in TS.PMID:38522940 | DOI:10.1507/endocrj.EJ23-0628 (Source: Endocrine Journal)
Source: Endocrine Journal - March 24, 2024 Category: Endocrinology Authors: Kento Ikegawa Eri Koga Tomoyo Itonaga Hideya Sakakibara Masanobu Kawai Yukihiro Hasegawa Source Type: research

Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction
Endocr Rev. 2024 Mar 19:bnae010. doi: 10.1210/endrev/bnae010. Online ahead of print.ABSTRACTMultiple changes occur in hormonal regulation with aging and across various endocrine organs. These changes are associated with multiple age-related disorders and diseases. A better understanding of responsible underling biological mechanisms could help in the management of multiple endocrine disorders over and above hormone replacement therapy (HRT). Cellular senescence is involved in multiple biological aging processes and pathologies common in elderly individuals. Cellular senescence, which occurs in many older individuals but al...
Source: Atherosclerosis - March 19, 2024 Category: Cardiology Authors: Masayoshi Suda Karl H Paul Utkarsh Tripathi Tohru Minamino Tamara Tchkonia James L Kirkland Source Type: research

Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction
Endocr Rev. 2024 Mar 19:bnae010. doi: 10.1210/endrev/bnae010. Online ahead of print.ABSTRACTMultiple changes occur in hormonal regulation with aging and across various endocrine organs. These changes are associated with multiple age-related disorders and diseases. A better understanding of responsible underling biological mechanisms could help in the management of multiple endocrine disorders over and above hormone replacement therapy (HRT). Cellular senescence is involved in multiple biological aging processes and pathologies common in elderly individuals. Cellular senescence, which occurs in many older individuals but al...
Source: ENDOCR REV - March 19, 2024 Category: Endocrinology Authors: Masayoshi Suda Karl H Paul Utkarsh Tripathi Tohru Minamino Tamara Tchkonia James L Kirkland Source Type: research