Gut microbiota and female health
World J Gastroenterol. 2024 Mar 28;30(12):1655-1662. doi: 10.3748/wjg.v30.i12.1655.ABSTRACTThe gut microbiota is recognized as an endocrine organ with the capacity to influence distant organs and associated biological pathways. Recent advancements underscore the critical role of gut microbial homeostasis in female health; with dysbiosis potentially leading to diseases among women such as polycystic ovarian syndrome, endometriosis, breast cancer, cervical cancer, and ovarian cancer etc. Despite this, there has been limited discussion on the underlying mechanisms. This editorial explores the three potential mechanisms throug...
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Meng-Yao Wang Li-Xuan Sang Si-Yu Sun Source Type: research
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
CONCLUSION: To the best of our knowledge, there have been no prior reports of cardiac metastasis of esophageal SCC. This case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease, with the autopsy examination showing cardiac metastasis.PMID:38617457 | PMC:PMC11008411 | DOI:10.3748/wjg.v30.i11.1636 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Source Type: research
Gut microbiota and female health
World J Gastroenterol. 2024 Mar 28;30(12):1655-1662. doi: 10.3748/wjg.v30.i12.1655.ABSTRACTThe gut microbiota is recognized as an endocrine organ with the capacity to influence distant organs and associated biological pathways. Recent advancements underscore the critical role of gut microbial homeostasis in female health; with dysbiosis potentially leading to diseases among women such as polycystic ovarian syndrome, endometriosis, breast cancer, cervical cancer, and ovarian cancer etc. Despite this, there has been limited discussion on the underlying mechanisms. This editorial explores the three potential mechanisms throug...
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Meng-Yao Wang Li-Xuan Sang Si-Yu Sun Source Type: research
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
CONCLUSION: To the best of our knowledge, there have been no prior reports of cardiac metastasis of esophageal SCC. This case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease, with the autopsy examination showing cardiac metastasis.PMID:38617457 | PMC:PMC11008411 | DOI:10.3748/wjg.v30.i11.1636 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Source Type: research
Socioeconomic inequalities in cancer incidence and mortality: An analysis of GLOBOCAN 2022
CONCLUSIONS: Infection- and poverty-related cancer burdens are offset by increased prostate, breast, colorectal, and lung cancer incidence associated with rapid societal and economic transitions. Cancer incidence and mortality patterns in China feature characteristics of developed and developing countries, necessitating tailored, evidence-based, and comprehensive strategies for effective cancer prevention and control.PMID:38616547 | DOI:10.1097/CM9.0000000000003140 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 15, 2024 Category: General Medicine Authors: Wei Cao Kang Qin Feng Li Wanqing Chen Source Type: research
Plasma Thioredoxin Reductase as a Potential Diagnostic Biomarker for Breast Cancer
CONCLUSION: Plasma TrxR activity can be used as a suitable biomarker for breast cancer diagnosis and efficacy assessment.PMID:38616444 | DOI:10.1016/j.clbc.2024.03.008 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Yixuan Hu Yinxing Zhu Junfeng Shi Xiaowei Wei Cuiju Tang Xiaoxiang Guan Wenwen Zhang Source Type: research
Efficacy of an aloe vera, chamomile, and thyme cosmetic cream for the prophylaxis and treatment of mild dermatitis induced by radiation therapy in breast cancer patients (the Alantel study)
CONCLUSIONS: The higher efficacy of Alantel® compared to the control cream in reducing the incidence of RD in women with breast cancer has been demonstrated.PMID:38616815 | PMC:PMC11010796 | DOI:10.1016/j.conctc.2024.101288 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: E Villegas-Becerril C Jimenez-Garcia L A Perula-de Torres M Espinosa-Calvo C M Bueno-Serrano F Romero-Ruperto F Gines-Santiago M C Moreno-Manzanaro J J Mu ñoz-Gavilan G Montes-Redondo M A Quesada-Roman M C Linares-Ramirez J M Parras-Rejano N Mu ñoz-Alca Source Type: research
Predictive medicine in a testis trio-family through a combined multi-omics approach
Clin Transl Med. 2024 Apr;14(4):e1643. doi: 10.1002/ctm2.1643.NO ABSTRACTPMID:38616705 | DOI:10.1002/ctm2.1643 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Federica Di Maggio Gianluca Damaggio Marcella Nunziato Silvia Buonaiuto Felice Crocetto Alessandra Calabrese Achille Aveta Gioacchino Vino Giacinto Donvito Savio Domenico Pandolfo Ciro Imbimbo Vincenza Colonna Francesco Salvatore Source Type: research
Systemic Therapy Advances for HER2-Positive and Triple Negative Breast Cancer: What the Surgeon Needs to Know
Clin Breast Cancer. 2024 Mar 13:S1526-8209(24)00077-6. doi: 10.1016/j.clbc.2024.03.004. Online ahead of print.ABSTRACTNeoadjuvant systemic therapy (NST) was initially reserved for unresectable patients however it has been increasingly used to facilitate breast conservation, downstage the axilla, and inform adjuvant therapy decisions based on response. For patients with HER2+ and triple-negative breast cancer (TNBC), clinical trials have resulted in the ability to individualize treatment regimens. For HER2+ breast cancer, de-escalation of neoadjuvant regimens to minimize cytotoxic chemotherapy and de-escalation or escalatio...
Source: Clinical Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Stephanie Downs-Canner Anna Weiss Source Type: research
Efficacy of an aloe vera, chamomile, and thyme cosmetic cream for the prophylaxis and treatment of mild dermatitis induced by radiation therapy in breast cancer patients (the Alantel study)
CONCLUSIONS: The higher efficacy of Alantel® compared to the control cream in reducing the incidence of RD in women with breast cancer has been demonstrated.PMID:38616815 | PMC:PMC11010796 | DOI:10.1016/j.conctc.2024.101288 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 15, 2024 Category: Cancer & Oncology Authors: E Villegas-Becerril C Jimenez-Garcia L A Perula-de Torres M Espinosa-Calvo C M Bueno-Serrano F Romero-Ruperto F Gines-Santiago M C Moreno-Manzanaro J J Mu ñoz-Gavilan G Montes-Redondo M A Quesada-Roman M C Linares-Ramirez J M Parras-Rejano N Mu ñoz-Alca Source Type: research
Plasma Thioredoxin Reductase as a Potential Diagnostic Biomarker for Breast Cancer
CONCLUSION: Plasma TrxR activity can be used as a suitable biomarker for breast cancer diagnosis and efficacy assessment.PMID:38616444 | DOI:10.1016/j.clbc.2024.03.008 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Yixuan Hu Yinxing Zhu Junfeng Shi Xiaowei Wei Cuiju Tang Xiaoxiang Guan Wenwen Zhang Source Type: research
Systemic Therapy Advances for HER2-Positive and Triple Negative Breast Cancer: What the Surgeon Needs to Know
Clin Breast Cancer. 2024 Mar 13:S1526-8209(24)00077-6. doi: 10.1016/j.clbc.2024.03.004. Online ahead of print.ABSTRACTNeoadjuvant systemic therapy (NST) was initially reserved for unresectable patients however it has been increasingly used to facilitate breast conservation, downstage the axilla, and inform adjuvant therapy decisions based on response. For patients with HER2+ and triple-negative breast cancer (TNBC), clinical trials have resulted in the ability to individualize treatment regimens. For HER2+ breast cancer, de-escalation of neoadjuvant regimens to minimize cytotoxic chemotherapy and de-escalation or escalatio...
Source: Clinical Genitourinary Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Stephanie Downs-Canner Anna Weiss Source Type: research
Genetic predisposition in chemotherapy ‐induced cardiomyopathy in a 65‐year‐old female with metastatic breast cancer
We present a case of a 65-year-old woman with breast cancer who developed recurrent CTRCD following low-dose chemotherapy, despite lacking conventional cardiovascular risk factors. Her medical history included anthracycline-associated cardiomyopathy, and her condition deteriorated significantly after treatment with HER2-targeted therapies. Through the use of multimodal imaging, we detected severe left ventricular systolic dysfunction. Further investigation with genetic testing revealed a likely pathogenic variant in theTNNT2 gene, suggesting a genetic predisposition to CTRCD. This case implies the potential role of genetic...
Source: ESC Heart Failure - April 15, 2024 Category: Cardiology Authors: So ‐Young Lee,
Hoon Seok Kim,
Mi‐Hyang Jung,
Suyon Chang,
Myungshin Kim,
Jong‐Chan Youn,
Woo‐Baek Chung,
Hae Ok Jung Tags: Case Report Source Type: research
Toxicity evaluation of dose-escalation in hypofractionated regional nodal irradiation for breast cancer: a retrospective study
Regional nodal irradiation (RNI) to the axilla and supraclavicular area presents distinct toxicities, such as lymphedema and shoulder stiffness, compared to whole-breast irradiation. There is insufficient evidence on the safety of dose-escalation in hypofractionated RNI. We aimed to evaluate and compare toxicity rates in patients with breast cancer who received hypofractionated RNI with and without dose-escalation. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - April 15, 2024 Category: Radiology Authors: Euidam Kim, Ji Sung Yoo, Yeon-Joo Kim, Jungnam Joo, Eun sang Oh, Yoonsun Chung, Seung Hyun Chung, Tae Hyun Kim Tags: Clinical Investigation Source Type: research
A historical and palaeopathological perspective on cancer.
Cancer is often wrongly considered to be a modern disease in many popular medical venues. Cancers have been known to mankind since ancient times. In fact, its antiquity can be proved through the application of palaeopathological methodologies.The present perspective piece demonstrates by means of a historical and palaeopathological analysis how oncological manifestations were present long before the emergence anatomically modern humans and addresses the epidemiological transition from ancient times to the contemporary world.The final section of the article is dedicated to the analysis of breast cancer and its identificatio...
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Francesco Maria Galassi, Elena Varotto, Mauro Vaccarezza, Mariano Martini, Veronica Papa Source Type: research
