Machine Learning Effectively Identifies Long QT Syndrome Machine Learning Effectively Identifies Long QT Syndrome
A machine learning model was more effective at detecting congenital long QT syndrome on resting ECGs than manual measurement of QT intervals by arrhythmia experts.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 21, 2024 Category: Cardiology Tags: Cardiology Source Type: news

Long QT Syndrome Overdiagnosis Persists Long QT Syndrome Overdiagnosis Persists
Five ' diagnostic miscues ' underlie overdiagnosis and misdiagnosis of long QT syndrome, which can profoundly affect patients ' quality of life.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - January 31, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Does Sports Participation Increase Risk in Patients With LQTS? Does Sports Participation Increase Risk in Patients With LQTS?
How great is the risk of cardiac arrhythmic events in persons with long QT syndrome who participate in athletic activity?Europace (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 2, 2022 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Science Saturday: Novel suppression-replacement preclinical gene therapy study shows promise in long and short QT syndromes
In a new study published in Circulation: Genomics& Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long QT syndrome (LQTS) and short QT syndrome (SQTS). LQTS is a genetic heart disease that can potentially cause fast, chaotic heartbeats. These rapid heartbeats might trigger people to faint suddenly. Some people with this disease have abnormal heart rhythm-mediated seizures and sudden cardiac arrest. In some severe cases, LQTS can cause sudden… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 19, 2022 Category: Databases & Libraries Source Type: news

Study Reassures on HCQ Heart Risks in Rheumatoid Arthritis
(MedPage Today) -- Among U.S. veterans receiving hydroxychloroquine (HCQ) as long-term therapy for rheumatoid arthritis, development of long QT syndrome was rare and not markedly more common compared with similar patients treated with other agents... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 2, 2022 Category: Rheumatology Source Type: news

The Evidence for the ILR in Inherited Arrhythmia Syndromes The Evidence for the ILR in Inherited Arrhythmia Syndromes
This literature review examined current evidence for the use of the implantable loop recorder in patients with inherited arrhythmias, including long QT syndrome, Brugada syndrome, and CPVT.Europace (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 31, 2022 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Menstrual Cycles Point to Link Between Sex Hormones and Long QT
(MedPage Today) -- SAN FRANCISCO -- Cardiac repolarization dynamics seemed to cycle in sync with the menstrual cycle of some people with congenital and drug-induced long QT syndrome (LQTS), a small prospective study showed. Women with LQTS type... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 2, 2022 Category: Cardiology Source Type: news

The Perfect Storm for Acquired Long QT Syndrome The Perfect Storm for Acquired Long QT Syndrome
This case highlights the need for proper assessment prior to prescribing QT prolonging medications, especially where there are risk factors for prolonged QT, such as electrolyte disturbances.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 2, 2022 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

LQT Therapeutics Announces Closing of US$19M Series A Financing to Advance Lead Compound Through Phase 1 while Advancing Portfolio Assets
Company established with world-class research from leading academia and industry leaders Lead program targets a novel kinase involved in cellular stress response Experienced and proven team advancing therapies for Long QT Syndrome and resistant cance... Biopharmaceuticals, Cardiology, Venture Capital LQT Therapeutics, Long QT Syndrome, SGK1 (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 10, 2021 Category: Pharmaceuticals Source Type: news

Return to Play Seems Safe for Most Athletes With Long QT Syndrome
WEDNESDAY, July 28, 2021 -- Twenty-year experience from a single center suggests that most athletes with long QT syndrome (LQTS) can safely return to play, according to a study published online July 27 in the Journal of the American College of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 28, 2021 Category: Pharmaceuticals Source Type: news

20-year Mayo Clinic study suggests return to play is manageable for athletes with most genetic heart diseases
ROCHESTER, Minn. — Receiving the diagnosis of a genetic heart disease such as long QT syndrome, which can cause sudden cardiac death, has long been a game-ender for young athletes. But a 20-year study at Mayo Clinic following such athletes who were allowed to return to play suggests that the risks can be managed t hrough a shared decision-making process. The retrospective study findings will be presented at the annual meeting of the Heart Rhythm Society… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - July 27, 2021 Category: Research Source Type: news

AI Crushes Expert Reader at ECG Recognition of Long-QT Syndrome AI Crushes Expert Reader at ECG Recognition of Long-QT Syndrome
It wasn ' t even close; the algorithms ' saw ' nuances on the tracings invisible to the eye and somehow flagged patients with ECG-concealed LQTS, even distinguishing them by genetic type.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 18, 2021 Category: Consumer Health News Tags: Cardiology News Source Type: news

First hybrid gene therapy shows early promise in treating long QT syndrome
ROCHESTER, Minn. ? In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. Researchers demonstrated its potential therapeutic efficacy in two in vitro model systems using beating heart cells reengineered from the blood samples of [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 28, 2021 Category: Research Source Type: news

What Causes Bradycardia?
Discussion Bradycardia is a heart rate below what the lowest value that is normal for age. Infants and children have higher heart rates that slowly decrease with age to adult levels. It is usually noted as an incidental finding because of increased vagal tone. Reasons for cardiology referral include associated heart murmur, syncope especially if associated with exercise or unusual triggers, other signs such as chest pain or palpitations, family history of sudden cardiac death, congenital heart disease or familial heart disease, bradycardic medication use, or unusual symptoms associated with the concern. Severe bradycardia ...
Source: PediatricEducation.org - June 22, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

U.S. FDA Approves New Pediatric Formulation of SIRTURO ® (bedaquiline) as Part of Combination Therapy to Treat Children with Pulmonary Multidrug-Resistant Tuberculosis
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelerated appro...
Source: Johnson and Johnson - May 27, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news