Placental Group B Strep Tied to Neonatal Unit Admission in Infants Born at Term
FRIDAY, Dec. 29, 2023 -- Detection of Streptococcus agalactiae (Group B Streptococcus; GBS) in the placenta is associated with an increased risk for neonatal unit (NNU) admission, according to a study published online Nov. 29 in Nature... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 29, 2023 Category: Pharmaceuticals Source Type: news
Maternal Vaccine Can Prevent Group B Strep in Young Infants
FRIDAY, July 21, 2023 -- A hexavalent capsular polysaccharide (CPS)-cross-reactive material 197 glycoconjugate vaccine (GBS6) can prevent invasive group B streptococcus in young infants, according to a study published in the July 20 issue of the New... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 21, 2023 Category: Pharmaceuticals Source Type: news
Pfizer announces New England Journal of Medicine publication on Group B Streptococcus (GBS) maternal vaccine candidate
Pfizer Inc. (NYSE: PFE) announced data from a Phase 2 study investigating its hexavalent capsular polysaccharide (CPS) conjugate Group B Streptococcus (GBS) vaccine candidate, GBS6, being developed for maternal administration to protect infants against invasive GBS disease. In stage two of the three-part study, which enrolled 360 healthy pregnant individuals, GBS6 generated robust maternal antibody responses against the six GBS CPS serotypes included in the vaccine, and these antibodies were efficiently transferred to infants at ratios of ~0.4-1.3 depending on GBS6 group. (Source: World Pharma News)
Source: World Pharma News - July 21, 2023 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news
Is a ‘polyepidemic’ humanity’s next big threat? Childhood vaccine crusader shares concerns for future
By the start of 2011, the year epidemiologist Seth Berkley became CEO of Gavi, the Vaccine Alliance, the ambitious nonprofit had over its 11-year history supported the immunization of 288 million children in poor countries. But it also had a $3.7 billion funding gap between its plans and donor financial pledges. Making matters worse, an internal battle raged about how much it should invest in strengthening health systems versus more technological solutions, such as new or improved vaccines, favored by its main funder, the Bill & Melinda Gates Foundation. “It was a crisis,” Berkley says.
Berkley plans to step ...
Source: ScienceNOW - July 20, 2023 Category: Science Source Type: news
Maternal Vaccine Promising for Invasive Group B Strep in Infants
(MedPage Today) -- A vaccine given during pregnancy produced antibodies against group B streptococcus that were transferred to infants at IgG thresholds associated with a reduced risk of invasive group B streptococcal disease, a phase II randomized... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - July 19, 2023 Category: Infectious Diseases Source Type: news
Kids' Epilepsy Tied to Group B Strep Meningitis, not Sepsis, in Infancy
(MedPage Today) -- Epilepsy in early childhood was significantly elevated among those infected in early infancy with invasive Group B Streptococcus (iGBS) meningitis, but not in those with iGBS sepsis, according to a matched cohort study out of... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - April 21, 2023 Category: Infectious Diseases Source Type: news
Benefits of Maternal Immunization Against Group B Strep Explored
TUESDAY, March 21, 2023 -- Maternal immunization against group B Streptococcus (GBS) could have a large impact on infant morbidity and mortality and is likely to be cost-effective, according to a study published online March 14 in PLOS... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 21, 2023 Category: Pharmaceuticals Source Type: news
FDA grants Breakthrough Therapy Designation to Pfizer's Group B Streptococcus vaccine candidate
Pfizer Inc. (NYSE:PFE) today announced that its investigational Group B Streptococcus (GBS) vaccine candidate, GBS6 or PF-06760805, received Breakthrough Therapy Designation from the U.S. Food and Drug Administration (FDA) for the prevention of invasive GBS disease due to the vaccine serotypes in newborns and young infants by active immunization of their mothers during pregnancy. (Source: World Pharma News)
Source: World Pharma News - September 7, 2022 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news
Africa: 'Urgent' Need for Strep B Vaccine to Prevent Baby Deaths
[SciDev.Net] The World Health Organization (WHO) has called for urgent development of vaccines against Group B streptococcus, also known as GBS or Strep B, as new figures reveal that the bacterium is responsible for 150,000 deaths of babies worldwide each year. (Source: AllAfrica News: Pregnancy and Childbirth)
Source: AllAfrica News: Pregnancy and Childbirth - November 10, 2021 Category: OBGYN Source Type: news
Africa: Step Up Vaccines Against Group B Strep, Linked to Baby Deaths and Disability
[UN News] New vaccines are urgently needed against a common bacterium which is a major cause of preterm births, disability and babies' deaths globally, according to a UN-backed report published on Wednesday. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 3, 2021 Category: African Health Source Type: news
Step up vaccines against Group B strep, linked to baby deaths and disability
New vaccines are urgently needed against a common bacterium which is a major cause of preterm births, disability and babies’ deaths globally, according to a UN-backed report published on Wednesday. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - November 2, 2021 Category: International Medicine & Public Health Source Type: news
A CRISPR-Based Diagnostic for Rapid Group B Strep Screening A CRISPR-Based Diagnostic for Rapid Group B Strep Screening
A newly developed CRISPR-based assay could offer a fast and accurate means of detecting group B Streptococcus.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 21, 2021 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Neonatal meningitis: the immaturity of microbiota and epithelial barriers implicated
(Institut Pasteur) In a mouse model, scientists from the Institut Pasteur, in collaboration with Inserm, Universit é de Paris and Necker-Enfants Malades Hospital (AP-HP) demonstrated that the immaturity of both the gut microbiota and epithelial barriers such as the gut and choroid plexus play a role in the susceptibility of newborn infants to bacterial meningitis caused by group B streptococcus (GBS). The findings were published in the journal Cell Reports on June 29, 2021 (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 9, 2021 Category: International Medicine & Public Health Source Type: news
Maternal Sepsis: presentation, course, treatment and outcomes
The current adult definition of sepsis and septic shock, as developed in 1992, does not adequately define sepsis in the pregnant and peripartum women due to the alteration of sepsis presentation in the maternal population. The purpose of this study was to determine potential causative factors for sepsis with the aim of prevention and reducing morbidity and mortality. Study Design and Methods: A descriptive observational design via a retrospective medical record review was used with a convenience sample of 22 women who were identified after admission as having sepsis. The setting was the labor and delivery unit of a large u...
Source: Current Awareness Service for Health (CASH) - June 9, 2021 Category: Consumer Health News Source Type: news
Babies surviving Group B strep more likely to require special educational support
(London School of Hygiene& Tropical Medicine) Invasive Group B Streptococcus (GBS) disease, notably meningitis, during the first days and months of a baby's life can have persistent effects for children and hence their families, according to new research. Published in the Lancet Child& Adolescent Health, the study is the first evidence of long-term effects including after GBS sepsis (infection in the bloodstream). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 21, 2021 Category: Infectious Diseases Source Type: news
