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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 4.

Exposure study to examine chemosensory effects of ɛ-caprolactam in healthy men and women.
CONCLUSIONS: Exposure to ε-caprolactam concentrations of 5.0 mg/m³ at maximum for 6 h did not cause chemosensory effects on the upper respiratory tract or eyes of healthy volunteers. Therefore, the concentration of 5.0 mg/m³ corresponds to the No Observed Adverse Effect Level (NOAEL). PMID: 27644138 [PubMed - as supplied by publisher] (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - September 22, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

A scattering methodology for droplet sizing of e-cigarette aerosols.
CONCLUSION: The LAS instrument can be used to measure e-cigarette aerosol droplet size distributions with a bias underestimating the expected value by 15-20% when using a precise PSL calibration curve. Controlled variability of DEHS size measurements can be achieved with the LAS system; however, this method can only be applied to test aerosols having a refractive index close to that of PSL particles used for calibration. PMID: 27644268 [PubMed - as supplied by publisher] (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - September 22, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Angiotensin-converting enzyme gene polymorphisms might be associated with childhood asthma in East Asia.
Authors: Shuluan Y, Ao S, Jun L, Jiaqing M, Lechun L PMID: 27645324 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - September 22, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Decreased TGF- β 1 and VEGF Release in Cystic Fibrosis Platelets: Further Evidence for Platelet Defects in Cystic Fibrosis
ConclusionPlatelet release is not a source of the elevated blood proinflammatory cytokines TGF- β1 and VEGF in CF, as platelets from CF patients actually release less of these cytokines. These data provide further evidence for platelet defects in CF. (Source: Lung)
Source: Lung - September 22, 2016 Category: Respiratory Medicine Source Type: research

Erratum to: Comparison of Pulmonary Involvement Between Patients Expressing Anti-PL-7 and Anti-Jo-1 Antibodies
(Source: Lung)
Source: Lung - September 22, 2016 Category: Respiratory Medicine Source Type: research

Non-Tuberculous Mycobacteria: Classification, Diagnostics, and Therapy.
Authors: Porvaznik I, Solovič I, Mokrý J Abstract Non-tuberculous mycobacteria (NTM) are species other than those belonging to the Mycobacterium tuberculosis complex and do not cause leprosy. NTM are generally free-living organisms that are ubiquitous in the environment. There have been more than 140 NTM species identified to-date. They can cause a wide range of infections, with pulmonary infections being the most frequent (65-90 %). There is growing evidence that the incidence of NTM lung diseases and associated hospitalizations are on the rise, mainly in regions with a low prevalence of tuberculosis. A crucia...
Source: Advances in Experimental Medicine and Biology - September 22, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

Cigarette Smoking and Respiratory System Diseases in Adolescents.
In conclusion, males more often than females smoked cigarettes. The number of persons complaining of symptoms of chronic bronchitis was markedly higher in the group of smokers. The study shows that smoking is a key cause of chronic bronchitis in adolescents. That implies a need for enhanced educational activity on the adverse effects of smoking and undertaking active anti-smoking campaigns at the level of high school. PMID: 27645541 [PubMed - as supplied by publisher] (Source: Advances in Experimental Medicine and Biology)
Source: Advances in Experimental Medicine and Biology - September 22, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

Diagnosis of Invasive Pulmonary Aspergillosis.
Authors: Swoboda-Kopeć E, Sikora M, Piskorska K, Gołaś M, Netsvyetayeva I, Przybyłowska D, Mierzwińska-Nastalska E Abstract Culturing strains from clinical samples is the main method to diagnose invasive pulmonary aspergillosis. Detecting the galactomannan antigen in serum samples is an auxiliary examination. The goal of this study was to determine the frequency with which Aspergillus fumigatus was cultured in clinical samples taken from patients hospitalized in the the Infant Jesus Teaching Hospital in Warsaw, Poland, in the period of 2013-2014. Specimens from the respiratory tract and blood were cultured for...
Source: Advances in Experimental Medicine and Biology - September 22, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

Acute Response to Cigarette Smoking Assessed in Exhaled Breath Condensate in Patients with Chronic Obstructive Pulmonary Disease and Healthy Smokers.
Authors: Maskey-Warzęchowska M, Nejman-Gryz P, Osinka K, Lis P, Malesa K, Górska K, Krenke R Abstract The effect of acute exposure to cigarette smoke (CS) on the respiratory system has been less extensively studied than the long term effects of smoking. The aim of the present study was to evaluate the acute response to CS in smokers suffering from chronic obstructive pulmonary disease (COPD) and in healthy smokers. Nineteen stable COPD patients and 19 young healthy smokers were enrolled. Tumor necrosis factor alpha (TNF-α), IL-1β, and malondialdehyde (MDA) were measured in exhaled breath condensate (EBC) before...
Source: Advances in Experimental Medicine and Biology - September 22, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

Liquid extracorporeal carbon dioxide removal: use of THAM (tris-hydroxymethyl aminomethane) coupled to hemofiltration to control hypercapnic acidosis in a porcine model of protective mechanical ventilation.
Authors: Tapia P, Lillo F, Soto D, Escobar L, Simon F, Hernández K, Alegría L, Bruhn A Abstract A promising approach to facilitate protective mechanical ventilation is the use of extracorporeal CO2 removal techniques. Several strategies based on membrane gas exchangers have been developed. However, these techniques are still poorly available. The goal of this study was to assess the efficacy and safety of THAM infusion coupled to hemofiltration for the management of hypercapnic acidosis. A severe respiratory acidosis was induced in seven anesthetized pigs. Five of them were treated with THAM 8-mmol·kg(-1)·h(-1)...
Source: American Journal of Translational Research - September 22, 2016 Category: Research Tags: Am J Transl Res Source Type: research

A HuR/TGF- β1 feedback circuit regulates airway remodeling in airway smooth muscle cells
Asthma is a worldwide health burden with an alarming prevalence. For years, asthma-associated airway injury remains elusive. Transforming growth factor β1 (TGF-β1) is a pleiotropic cytokine that has been shown... (Source: Respiratory Research)
Source: Respiratory Research - September 22, 2016 Category: Respiratory Medicine Authors: Na Wang, Di Yan, Yi Liu, Yao Liu, Xianmin Gu, Jian Sun, Fei Long and Shujuan Jiang Source Type: research

The genetic and epigenetic landscapes of the epithelium in asthma
Asthma is a global health problem with increasing prevalence. The airway epithelium is the initial barrier against inhaled noxious agents or aeroallergens. In asthma, the airway epithelium suffers from structu... (Source: Respiratory Research)
Source: Respiratory Research - September 22, 2016 Category: Respiratory Medicine Authors: Fatemeh Moheimani, Alan C-Y Hsu, Andrew T Reid, Teresa Williams, Anthony Kicic, Stephen M. Stick, Philip M. Hansbro, Peter A.B. Wark and Darryl A. Knight Source Type: research

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis
The activity of cysteine cathepsin B increased markedly in lung homogenates and in bronchoalveolar lavage fluids (BALF) of the mouse model of bleomycin-induced lung fibrosis after 14  days of challenge. In cont... (Source: Respiratory Research)
Source: Respiratory Research - September 22, 2016 Category: Respiratory Medicine Authors: Mariana Kasabova, B érengère Villeret, Aurélie Gombault, Fabien Lecaille, Thomas Reinheckel, Sylvain Marchand-Adam, Isabelle Couillin and Gilles Lalmanach Source Type: research

The added value of C-reactive protein measurement in diagnosing pneumonia in primary care: a meta-analysis of individual patient data.
Authors: Minnaard MC, de Groot JA, Hopstaken RM, Schierenberg A, de Wit NJ, Reitsma JB, Broekhuizen BD, van Vugt SF, Knuistingh Neven A, Graffelman AW, Melbye H, Rainer TH, Steurer J, Holm A, Gonzales R, Dinant GJ, van de Pol AC, Verheij TJ Abstract BACKGROUND: C-reactive protein (CRP) is increasingly being included in the diagnostic work-up for community-acquired pneumonia in primary care. Its added diagnostic value beyond signs and symptoms, however, remains unclear. We conducted a meta-analysis of individual patient data to quantify the added value of CRP measurement. METHODS: We included studies of the diag...
Source: Canadian Medical Association Journal - September 22, 2016 Category: Journals (General) Tags: CMAJ Source Type: research

Association of biofilm production with colonization among clinical isolates of Acinetobacter baumannii.
Conclusions: Biofilm-producing isolates seem to colonize the respiratory tract for longer durations than the non-biofilm producing isolates. During colonization, biofilm producers promote co-colonization by other bacteria, particularly S. aureus. Additional research is required to determine possible links between biofilm formation and nosocomial infection. PMID: 27653617 [PubMed - as supplied by publisher] (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - September 22, 2016 Category: Internal Medicine Authors: Ryu SY, Baek WK, Kim HA Tags: Korean J Intern Med Source Type: research

Autophagy activation in COL6 myopathic patients by a low-protein-diet pilot trial.
Abstract A pilot clinical trial based on nutritional modulation was designed to assess the efficacy of a one-year low-protein diet in activating autophagy in skeletal muscle of patients affected by COL6/collagen VI-related myopathies. Ullrich congenital muscular dystrophy and Bethlem myopathy are rare inherited muscle disorders caused by mutations of COL6 genes and for which no cure is yet available. Studies in col6 null mice revealed that myofiber degeneration involves autophagy defects and that forced activation of autophagy results in the amelioration of muscle pathology. Seven adult patients affected by COL6 m...
Source: Autophagy - September 22, 2016 Category: Cytology Authors: Castagnaro S, Pellegrini C, Pellegrini M, Chrisam M, Sabatelli P, Toni S, Grumati P, Ripamonti C, Pratelli L, Maraldi NM, Cocchi D, Righi V, Faldini C, Sandri M, Bonaldo P, Merlini L Tags: Autophagy Source Type: research

Antiviral activity of aspirin against RNA viruses of the respiratory tract —an in vitro study
ConclusionsThese data demonstrate a specific antiviral activity of aspirin against influenza A virus and HRV. The mode of action against rhinoviruses is still unknown and requires further investigation, as does the possibility of aspirin being effective in vivo to treat the common cold. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - September 22, 2016 Category: Virology Authors: Bernadette Glatthaar ‐Saalmüller, Kerstin H. Mair, Armin Saalmüller Tags: Original Article Source Type: research

Brainstem sources of cardiac vagal tone and respiratory sinus arrhythmia.
This article is protected by copyright. All rights reserved. PMID: 27654879 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - September 22, 2016 Category: Physiology Authors: Farmer DG, Dutschmann M, Paton JF, Pickering AE, McAllen RM Tags: J Physiol Source Type: research

Quality Improvement of Nasal Continuous Positive Airway Pressure Therapy in Neonatal Intensive Care Unit
Nasal continuous positive airway pressure (NCPAP) therapy is widely used in neonates, but the clinical practice varies. However, nursing practice differs among individuals, and an inappropriate application method may delay the respiratory therapy, influence the beneficial effect of NCPAP, and increase complications. We introduced a quality improvement project to expedite the application of NCPAP therapy and decrease the incidence of nasal trauma. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - September 22, 2016 Category: Perinatology & Neonatology Authors: Chien-Yi Chen, An-Kuo Chou, Yu-Lien Chen, Hung-Chieh Chou, Po-Nien Tsao, Wu-Shiun Hsieh Tags: Original article Source Type: research

The ROS derived mitochondrial respirstion not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation
In this study, we studied the effect of celastrol on AngII-induced HepG2 cell proliferation and evaluated its underlying mechanism. The results revealed that AngII was able to significantly promote HepG2 cell proliferation via up-regulating AngII type 1 (AT1) receptor expression, improving mitochondrial respiratory function, enhancing nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity, increasing the levels of reactive oxygen species (ROS) and pro-inflammatory cytokines. The excess ROS from mitochondrial dysfunction is able to cause the apoptosis of tumor cells via activating caspase3 signal pathway. In a...
Source: Apoptosis - September 22, 2016 Category: Molecular Biology Source Type: research

Delayed severe abciximab-induced thrombocytopenia: A case report
Conclusion Although specific mechanisms of abciximab-related thrombocytopenia are still unclear and the management is not well established, the patient responded well to the therapy and his recovery was uneventful. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - September 22, 2016 Category: Respiratory Medicine Source Type: research

Specific needs, concerns, strategies and advice of caregivers after coronary artery bypass surgery
Conclusions The resounding need for a dedicated caregiver program to prepare partners for their role, including what to expect, warrants exploration. Future research should validate these concerns in more diverse samples so interventions can be targeted to better support caregivers. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - September 22, 2016 Category: Respiratory Medicine Source Type: research

Adaptation and coping in patients living with an LVAD: A metasynthesis
Conclusions Emotional challenges including fear and anxiety related to life-limiting illness and changed social roles need to be honestly addressed. Individuals living with LVAD achieve a sense of independence, enjoy social interactions and meaningful activities through addressing practical and emotional problems to facilitate coping. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - September 22, 2016 Category: Respiratory Medicine Source Type: research

Targeting heart failure rehospitalizations in a skilled nursing facility: A case report
Conclusion We highlight the benefits of a patient registry to guide future quality improvement initiatives to reduce patient rehospitalization rates. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - September 22, 2016 Category: Respiratory Medicine Source Type: research

Cognitive function and health literacy are independently associated with heart failure knowledge
Conclusions Impairments in health literacy and cognition were independently associated with reduced HF knowledge. Interventions should address both factors to be maximally effective. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - September 22, 2016 Category: Respiratory Medicine Source Type: research

De-escalation of empiric antibiotics in patients with severe sepsis or septic shock: A meta-analysis
Conclusion Antibiotic de-escalation therapy has no detrimental impact on mortality in patients with severe sepsis and/or septic shock, as compared to the continuation of broad-spectrum antibiotics. Since de-escalation affords an opportunity to limit overuse of broad-spectrum antibiotics, it should be considered as an option in clinical practice. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - September 22, 2016 Category: Respiratory Medicine Source Type: research

Adherence to infection prevention and control guidelines: A vignette-based study of decision-making and risk-taking in young adults with cystic fibrosis
Balancing cystic fibrosis (CF) care with demands of normal life is associated with decreased adherence to infection prevention and control (IPC) guidelines. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - September 22, 2016 Category: Respiratory Medicine Authors: Grace Bowmer, Gary Latchford, Alistair Duff, Miles Denton, Louise Dye, Clare Lawton, Tim Lee Tags: Original Article Source Type: research

Analytical and clinical performance characteristics of the Abbott RealTime MTB RIF/INH Resistance, an assay for the detection of Rifampicin and Isoniazid resistant Mycobacterium tuberculosis in pulmonary specimens
This article summarizes the performance of the Abbott RealTime MTB RIF/INH Resistance assay; including reliability, analytical sensitivity, and clinical sensitivity/specificity as compared to Cepheid GeneXpert MTB/RIF version 1.0 and Hain MTBDRplus version 2.0. (Source: Tuberculosis)
Source: Tuberculosis - September 22, 2016 Category: Respiratory Medicine Authors: Joshua Kostera, Gregor Leckie, Ning Tang, John Lampinen, Magdalena Szostak, Klara Abravaya, Hong Wang Tags: Diagnostics Source Type: research

Incidence of oral thrush in patients with COPD prescribed inhaled corticosteroids: Effect of drug, dose, and device
Little information is available on real-life occurrence of oral thrush in COPD patients treated with ICS. We investigated oral thrush incidence in COPD patients prescribed FDC ICS/LABA therapies and assessed whether it is modulated by the ICS type, dose, and delivery device. (Source: Respiratory Medicine)
Source: Respiratory Medicine - September 22, 2016 Category: Respiratory Medicine Authors: P.N. Richard Dekhuijzen, Maria Batsiou, Leif Bjermer, Sinthia Bosnic-Anticevich, Henry Chrystyn, Alberto Papi, Roberto Rodr íguez-Roisin, Monica Fletcher, Lucy Wood, Alessandra Cifra, Joan B. Soriano, David B. Price Source Type: research

The transition from intra to extra-uterine life in late preterm infant: a single-center study
ConclusionsTransition period in LPIs may become critical, as resuscitation strategies can be required and heat loss can occur. LPIs, especially at 34 gestational weeks, are higher-risk group needing adequate and targeted management at birth. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 22, 2016 Category: Pediatrics Source Type: research

Prescriber preferences for behavioural economics interventions to improve treatment of acute respiratory infections: a discrete choice experiment
Conclusions Prescribing behaviour and stated preferences are not concordant, suggesting that relying on stated preferences alone to inform intervention design may eliminate effective interventions. Trial registration number NCT01454947; Results. (Source: BMJ Open)
Source: BMJ Open - September 22, 2016 Category: Journals (General) Authors: Gong, C. L., Hay, J. W., Meeker, D., Doctor, J. N. Tags: Open access, Health economics, Health services research, Infectious diseases, Respiratory medicine Source Type: research

Respiratory viruses and influenza-like illness: epidemiology and outcomes in children aged 6 months to 10 years in a multi-country population sample
Better population data on respiratory viruses in children in tropical and southern hemisphere countries is needed. (Source: Journal of Infection)
Source: Journal of Infection - September 22, 2016 Category: Infectious Diseases Authors: Sylvia Taylor, Pio Lopez, Lily Weckx, Charissa Borja-Tabora, Rolando Ulloa-Gutierrez, Eduardo Lazcano-Ponce, Angkool Kerdpanich, Miguel Angel Rodriguez Weber, Abiel Mascare ñas de Los Santos, Juan-Carlos Tinoco, Marco Aurelio P. Safadi, Lim Fong Seng, Ma Source Type: research

The impact of measurement of respiratory quotient by indirect calorimetry on the achievement of nitrogen balance in patients with severe traumatic brain injury
ConclusionAn increase in kcal ≥25 % in patients with a RQ <  0.83 on day 3 improves substrate utilization, decreases protein utilization and optimizes the achievement of +NB by day 7. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - September 22, 2016 Category: Emergency Medicine Source Type: research

Bovine respiratory syncytial virus and bovine coronavirus antibodies in bulk tank milk – risk factors and spatial analysis
Publication date: 1 October 2016 Source:Preventive Veterinary Medicine, Volume 133 Author(s): Ingrid Toftaker, Javier Sanchez, Maria Stokstad, Ane Nødtvedt Bovine respiratory syncytial virus (BRSV) and bovine coronavirus (BCoV) are considered widespread among cattle in Norway and worldwide. This cross-sectional study was conducted based on antibody-ELISA of bulk tank milk (BTM) from 1347 herds in two neighboring counties in western Norway. The study aims were to determine the seroprevalence at herd level, to evaluate risk factors for BRSV and BCoV seropositivity, and to assess how these factors were associated with the s...
Source: Preventive Veterinary Medicine - September 22, 2016 Category: Veterinary Research Source Type: research

Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death
Conclusions QQ8c targets NDH-2 of the mycobacterial respiratory chain leading to activation of NADH oxidation and generating bactericidal levels of ROS in a manner similar to, but more effectively than, the antimycobacterial drug clofazimine. Our results validate respiratory-generated ROS as an avenue for antimycobacterial drug development. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - September 22, 2016 Category: Microbiology Authors: Heikal, A., Hards, K., Cheung, C.-Y., Menorca, A., Timmer, M. S. M., Stocker, B. L., Cook, G. M. Tags: Original research Source Type: research

Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium
Conclusions The data support the idea that macrolides have antiviral properties through a mechanism that is yet to be ascertained. We also provide evidence that macrolides can be developed with anti-inflammatory, antibacterial and antiviral activity and show surprising versatility depending on the clinical need. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - September 22, 2016 Category: Microbiology Authors: Porter, J. D., Watson, J., Roberts, L. R., Gill, S. K., Groves, H., Dhariwal, J., Almond, M. H., Wong, E., Walton, R. P., Jones, L. H., Tregoning, J., Kilty, I., Johnston, S. L., Edwards, M. R. Tags: Original research Source Type: research

Blood Cell Respirometry is Associated with Skeletal and Cardiac Muscle Bioenergetics: Implications For a Minimally Invasive Biomarker of Mitochondrial Health
Publication date: Available online 21 September 2016 Source:Redox Biology Author(s): Daniel J. Tyrrell, Manish S. Bharadwaj, Matthew J. Jorgensen, Thomas C. Register, Anthony J.A. Molina Blood based bioenergetic profiling strategies are emerging as potential reporters of systemic mitochondrial function; however, the extent to which these measures reflect the bioenergetic capacity of other tissues is not known. The premise of this work is that highly metabolically active tissues, such as skeletal and cardiac muscle, are susceptible to differences in systemic bioenergetic capacity. Therefore, we tested whether the respirato...
Source: Redox Biology - September 22, 2016 Category: Biology Source Type: research

The unusual redox properties of C-type oxidases
Publication date: Available online 21 September 2016 Source:Biochimica et Biophysica Acta (BBA) - Bioenergetics Author(s): Frederic Melin, Hao Xie, Thomas Meyer, Young Ok Ahn, Robert B Gennis, Hartmut Michel, Petra Hellwig Cytochrome cbb 3 (also known as C-type) oxidases belong to the family of heme-copper terminal oxidases which couple at the end of the respiratory chain the reduction of molecular oxygen into water and the pumping of protons across the membrane. They are expressed most often at low pressure of O2 and they exhibit a low homology of sequence with the cytochrome aa 3 (A-type) oxidases found in mitochondria....
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - September 22, 2016 Category: Biochemistry Source Type: research

Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy
We describe four families with affected siblings showing unique clinical features: early-onset (before 1 year of age) progressive diffuse brain atrophy with regression, postnatal microcephaly, postnatal growth retardation, muscle weakness/atrophy, and respiratory failure. By whole-exome sequencing, we identified biallelic TBCD mutations in eight affected individuals from the four families. TBCD encodes TBCD (tubulin folding co-factor D), which is one of five tubulin-specific chaperones playing a pivotal role in microtubule assembly in all cells. (Source: The American Journal of Human Genetics)
Source: The American Journal of Human Genetics - September 22, 2016 Category: Genetics & Stem Cells Authors: Noriko Miyake, Ryoko Fukai, Chihiro Ohba, Takahiro Chihara, Masayuki Miura, Hiroshi Shimizu, Akiyoshi Kakita, Eri Imagawa, Masaaki Shiina, Kazuhiro Ogata, Jiu Okuno-Yuguchi, Noboru Fueki, Yoshifumi Ogiso, Hiroshi Suzumura, Yoshiyuki Watabe, George Imataka Tags: Report Source Type: research

Exogenous lipoid pneumonia induced by nasal decongestant
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 22, 2016 Category: Respiratory Medicine Authors: Giorgia Amira Osman, Alberto Ricci, Fabrizio Terzo, Carlo Falasca, Maria Rosaria Giovagnoli, Pierdonato Bruno, Andrea Vecchione, Salvatore Raffa, Sabatino Valente, Maria Rosaria Torrisi, Chiara De Dominicis, Simonetta Giovagnoli, Salvatore Mariotta Tags: Original Article Source Type: research

Agreement between adherences to four physical activity recommendations in patients with COPD: Does the incremental shuttle walk test predict adherence?
Conclusion Agreement between various physical activity recommendations is poor. This should be considered when measuring and describing physical activity adherence. The ISWT cannot be used to reliably predict adherence to physical activity guidelines. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 22, 2016 Category: Respiratory Medicine Authors: Katy E Mitchell, Vicki Johnson, Linzy Houchen ‐Wolloff, Louise Sewell, Mike D Morgan, Michael C Steiner, Sally J Singh Tags: Original Article Source Type: research

Fostering the exchange of real-life data across different countries to answer primary care research questions: a protocol for an UNLOCK study from the IPCRG
npj Primary Care Respiratory Medicine, Published online: 22 September 2016; doi:10.1038/npjpcrm.2016.48 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - September 22, 2016 Category: Primary Care Authors: Liza Cragg Si ân Williams Thys van der Molen Mike Thomas Jaime Correia de Sousa Niels H Chavannes Source Type: research

Development and Initial Validation of a Questionnaire to Measure Health-Related Quality of Life of Adults with Common Variable Immune Deficiency: The CVID_QoL Questionnaire
Conclusions This study provides evidence of the reliability and construct validity of the CVID_QoL to identify QoL issues in patients with CVID that may not be addressed by generic instruments. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2016 Category: Allergy & Immunology Source Type: research

Home Environmental Interventions for the Prevention or Control of Allergic and Respiratory Diseases: What Really Works
Publication date: Available online 21 September 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Pierre Le Cann, Hélène Paulus, Philippe Glorennec, Barbara Le Bot, Sophie Frain, Jean Pierre Gangneux Home health care workers interventions have been implemented in western countries to improve health status of patients with respiratory diseases especially asthma and allergic illnesses. Twenty-six controlled studies dealing with prevention and control of these diseases through home environmental interventions were reviewed. After a comprehensive description of the characteristics of these s...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2016 Category: Allergy & Immunology Source Type: research

Prescription practices for non-malaria febrile illnesses among under-fives in the Lake Zone, Tanzania
Conclusions The proportion of clinicians prescribing antimalarial medications and over-prescribing antibiotics to malaria negative-tested under-fives in the Lake Zone is high, 11%, and as low as 14% of clinicians prescribed antibiotics correctly based on correct final diagnoses. Training of health care workers, health managers and regular supportive supervision may significantly improve prescription practices among clinicians attending under-fives. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - September 22, 2016 Category: Tropical Medicine Source Type: research

Detection of porcine reproductive and respiratory syndrome virus (PRRSV) and influenza A virus (IAV) in oral fluid of pigs
The objective of the study was to analyze porcine reproductive and respiratory syndrome virus (PRRSV) and influenza A virus (IAV) circulation in growing pigs from three Polish production farms, using Real Time PCR and ELISA testing of oral fluid and serum. Oral fluids were collected every 2weeks, in the same 3–4 pens of pigs aged between 5 and 17weeks. Additionally, blood samples were collected every 4weeks from 4 pigs corresponding to the same pens as oral fluid and tested for the presence of PRRSV nucleic acid (pooled by 4) and antibodies. In farm A no PRRSV circulation was detected and only maternal antibodies were pr...
Source: Research in Veterinary Science - September 22, 2016 Category: Veterinary Research Source Type: research

Safety of long-acting β2-agonists in asthma
Publication date: Available online 21 September 2016 Source:The Lancet Respiratory Medicine Author(s): Louise Rishton (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - September 22, 2016 Category: Respiratory Medicine Source Type: research

SAVE trial: no cardiovascular benefits for CPAP in OSA
Publication date: Available online 21 September 2016 Source:The Lancet Respiratory Medicine Author(s): Bryant Furlow (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - September 22, 2016 Category: Respiratory Medicine Source Type: research

Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model.
Authors: Uyama K, Sakiyama S, Yoshida M, Kenzaki K, Toba H, Kawakami Y, Okumura K, Takizawa H, Kondo K, Tangoku A Abstract The mortality and morbidity of chronic obstructive pulmonary disease are high. However, no radical therapy has been developed to date. The purpose of this study was to evaluate whether fetal mouse lung tissue can grow and differentiate in the emphysematous lung. Fetal lung tissue from green fluorescent protein C57BL/6 mice at 16 days' gestation was used as donor material. Twelve-month-old pallid mice were used as recipients. Donor lungs were cut into small pieces and implanted into the recipien...
Source: Journal of Medical Investigation - September 21, 2016 Category: Journals (General) Tags: J Med Invest Source Type: research

Experiences and Psychosocial Impact of West Africa Ebola Deployment on US Health Care Volunteers
CONCLUSIONS The urge to do something to help in an international medical crisis is understandable and admirable, but the adverse impacts reported by participants here – at every stage of deployment, suggest that preparedness for these missions needs improvement and at the very least, high risk missions should be limited to more seasoned and well trained (for conditions in the field) personnel. While volunteering for a medical mission during a health crisis can be very rewarding, both professionally and personally, it can also be very disruptive and impactful. All volunteers for high risk missions must be made fully aware...
Source: PLOS Currents Outbreaks - September 21, 2016 Category: Epidemiology Authors: Robyn Gershon Source Type: research