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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 4.

CB1 receptor-mediated respiratory depression by endocannabinoids
Publication date: Available online 22 February 2017 Source:Respiratory Physiology & Neurobiology Author(s): András Iring, László Hricisák, Zoltán Benyó Endocannabinoids (ECs) are bioactive lipid mediators acting on two distinct cannabinoid receptors (CB1 and CB2), which are ubiquitously expressed in many tissues including the respiratory system. Despite numerous experimental data showing that cannabinomimetics influence respiration, the role of endogenously produced ECs in respiratory control has not been verified yet. Pulse oximetry was used in the present study to directly measure changes in respiratory pa...
Source: Respiratory Physiology and Neurobiology - February 23, 2017 Category: Respiratory Medicine Source Type: research

Effect of cricoid pressure on laryngeal view during prehospital tracheal intubation: a propensity-based analysis
Conclusions No significant relationship was found between the use of cricoid pressure for prehospital intubation and difficult laryngoscopy. Cricoid pressure was found to be associated with more airway trauma. This finding could question its routine use. (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - February 23, 2017 Category: Emergency Medicine Authors: Caruana, E., Chevret, S., Pirracchio, R. Tags: Editor's choice, Drugs: cardiovascular system, Surgical diagnostic tests Original article Source Type: research

Effect of Ivacaftor on Objective and Subjective Measures of Cough in Patients with Cystic Fibrosis.
CONCLUSION: We have observed early subjective and objective improvement in cough measures on treatment with ivacaftor. We suggest that this improvement could be attributed to improvement of gastro-intestinal function and that cough metrics could be used as early and accurate end points of drug efficacy. PMID: 28217196 [PubMed - in process] (Source: Open Respiratory Medicine Journal)
Source: Open Respiratory Medicine Journal - February 22, 2017 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Effect of Short-Term Exposure to High Particulate Levels on Cough Reflex Sensitivity in Healthy Tourists: A Pilot Study.
CONCLUSION: We tentatively concluded that short-term exposure to high PM concentrations may have adverse effects on cough reflex and urge-to-cough thresholds, pulmonary function, and cough-related quality of life. PMID: 28217195 [PubMed - in process] (Source: Open Respiratory Medicine Journal)
Source: Open Respiratory Medicine Journal - February 22, 2017 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

The fraction of exhaled nitric oxide (feno) and forced oscillation technique (fot) can predict bronchial hyperresponsiveness against acetylcholine in treated asthmatics.
CONCLUSION: Combining R5 or R20 and FENO can predict the level of bronchial hyperresponsiveness in adult stable asthmatics. PMID: 28216536 [PubMed - in process] (Source: Arerugi)
Source: Arerugi - February 22, 2017 Category: Allergy & Immunology Authors: Fukuhara M, Tsuburai T, Nakamura Y, Tomita Y, Hamada Y, Watai K, Hayashi H, Kamide Y, Sekiya K, Mitsui C, Fukutomi Y, Mori A, Taniguchi M Tags: Arerugi Source Type: research

Effects of the nasal passage on forced oscillation lung function measurements.
Authors: Ngo C, Krüger K, Vollmer T, Winter S, Penzlin B, Lehmann S, Leonhardt S, Misgeld B Abstract The forced oscillation technique (FOT) is a non-invasive pulmonary function test which is based on the measurement of respiratory impedance. Recently, promising results were obtained by the application of FOT on patients with respiratory failure and obstructive sleep apnea (OSA). By using a nasal mask instead of a mouthpiece, the influences of the nasal passage and upper shunt alter the measured mechanical impedance. In this paper, we investigated the effects of the nasal passage and mask on FOT measurements from e...
Source: Biomedizinische Technik/Biomedical Engineering - February 22, 2017 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Human Rhinovirus Infections in Hematopoietic Cell Transplant Recipients: Factors Determining Progression to Lower Tract Disease
Background: Human rhinovirus (HRV) is the most common virus detected from respiratory specimens in hematopoietic cell transplant (HCT) recipients, largely due to the development of sensitive molecular viral detection techniques. HCT recipients are particularly susceptible to progression from upper respiratory tract infection (URTI) to lower respiratory tract infection (LRTI); however, few data exist regarding specific risk factors affecting disease progression. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Alpana Waghmare, Hu Xie, Jane M. Kuypers, Mohamed L. Sorror, Wendy M. Leisenring, Janet A. Englund, Michael J. Boeckh Source Type: research

Impact of Pretransplant Respiratory Virus Detection through Universal Screening in Children Undergoing Hematopoietic Cell Transplantation (HCT)
We examined the impact of pretransplant detection of 11 respiratory viruses in a pediatric HCT population. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Yae-Jean Kim, Alpana Waghmare, Jane M. Kuypers, Keith R. Jerome, Steven A. Pergam, Hu Xie, Wendy M. Leisenring, Chikara Ogimi, Michael J. Boeckh, Janet A. Englund Source Type: research

A Prospective Study of IV Pentamidine for Pneumocystis Jirovecii Pneumonia Prophylaxis in Adult Patients with Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplant or Chemotherapy
Pneumocystis jirovecii pneumonia (PJP) prophylaxis is routinely administered to patients undergoing hematopoietic stem cell transplantation (SCT) or intensive chemotherapy. There is continued risk of PJP in SCT recipients when they require prolonged immunosuppression or high dose corticosteroids. Trimethoprim-sulfamethoxazole is preferred but is limited by myelosuppression. Inhaled pentamidine is an alternative, but frequently causes bronchospasm, needs to be given by a respiratory therapist, and requires a private room for administration. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Karen Sweiss, Jennifer Anderson, Scott Wirth, John Quigley, Irum Khan, Annie Oh, Damiano Rondelli, Pritesh Rajni Patel Source Type: research

Prospective Assessment of Diagnostic Infectious Disease Molecular PCR Testing with Early Fiberoptic Bronchoscopy (FOB) in the Evaluation of New Pulmonary Infiltrates in Hematopoietic Stem Cell Transplantation (HSCT) and Acute Leukemia (AL) Patients (pts)
Pneumonia is a major cause of morbidity in pts undergoing HSCT and AL therapy. Early FOB with culture, cytopath and viral ELISA testing improves survival. Early FOB at our center historically identified causative microorganism(s) in 37% of pts (68/183). We conducted an IRB approved prospective early FOB trial in 49 pts undergoing HSCT or AL therapy with respiratory symptoms and new radiographic lung infiltrates to determine the impact of the rapid PCR panel combined with culture testing. The PCR panel included Mycoplasma, Chlamydia, HSV, VZV, HHV7, RSV, hMPV, Rhino/Coronavirus, Adenovirus, Influenza A/B, Parainfluenza Type...
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Melissa Sanacore, Stephanie Eaton, Lawrence E. Morris, Scott R. Solomon, Asad Bashey, Melhem Solh, H. Kent Holland Source Type: research

Impact of Respiratory Virus Infection before Hematopoietic Cell Transplantation (HCT) on Post-Transplant Outcomes in Adults in the PCR Era: Do Rhinovirus and Coronavirus Infections Matter?
This study was performed to revisit this question in a large cohort of HCT recipients who had PCR testing for evaluation of respiratory symptoms before HCT. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Yae-Jean Kim, Alpana Waghmare, Jane M. Kuypers, Keith R. Jerome, Steven A. Pergam, Hu Xie, Wendy M. Leisenring, Chikara Ogimi, Janet A. Englund, Michael J. Boeckh Source Type: research

Aromatherapy as Symptom Management for Hematology/Oncology/Blood and Marrow Transplant Patients
Topic Significance& Study Purpose/Background/Rationale: Common side effects of chemotherapy include nausea, vomiting, sleep disturbances, pain, and fatigue. The current medications used to treat these symptoms have many side effects, which can lead to adverse events such as respiratory depression and falls. Essential oils are low cost and have minimal side effects compared to the medications used. The aim of this project was to incorporate essential oils as an alternative or complimentary option to current side effect treatment regimens. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Kathryn A. Lochmann, Azure Grossman, Christina Ebert, Carolyn Gatton Source Type: research

The Effectiveness of Granulocyte Transfusions in Neutropenic Adult Oncology Patients
Topic Significance& Study Purpose/Background/Rationale: Among cancer patients, many factors can cause severe and persistent neutropenia, leading to increased morbidity and mortality. For patients with neutrophil deficiency, replacement with granulocyte transfusion (GTX) seems to be a rational approach. Existing data on the efficacy of GTX have been inconclusive, and such adverse effects as respiratory distress and death indicate the need for further investigation. The purpose of this literature review was to determine if granulocyte transfusions are effective in the management of adult oncology patients with neutropenia, f...
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Asha Elsa Demla Source Type: research

Respiratory Challenges in Inpatient BMT: “No Such Thing As ‘Flu Season”
Topic Significance& Study Purpose/Background/Rationale: Respiratory infections (e.g. influenza, RSV, parainfluenza) are major challenges year-round in the BMT population. Outbreaks pose major challenges for immunocompromised patients and the staff caring for them. Due to repeated respiratory outbreaks in BMT Units at XXX several positive changes were made in the approach to respiratory challenges. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Sara Barr, Paige Reason Source Type: research

Reducing the Risk of Sedation for Adult Bone Marrow Biopsy Patients: Establishing a New Protocol to Support Pain Control and Anxiolysis
Background: Prior to May 2015, our Adult BMT Clinic's premedication approach for a bone marrow biopsy (BMBX) procedure consisted of an opioid and lorazepam intravenous (IV) push. This practice did not meet our hospital credentialing or institutional policies for procedural sedation. The predominant concern was the potential risk of unintended over-sedation vs. the intended goal of anxiolysis. While there were no cases of respiratory depression or life-threatening side effects, a few patients required extended time in clinic due to the sedating effects of the drug combination. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Elaine Stenstrup, Sasha Skendzel, Erica Warlick, Leslie Parran Source Type: research

Affection of the Respiratory Muscles in Combined Complex I and IV Deficiency.
CONCLUSION: Mitochondrial myopathy due to a combined complex I+IV defect with predominant affection of the extra-ocular muscles may progress to involvement of the limb-girdle, axial and respiratory muscles resulting in muscular respiratory insufficiency. In patients with mitochondrial myopathy, neuropathy and elevated cerebrospinal fluid protein, immunoglobulins may be beneficial even for respiratory functions. PMID: 28217183 [PubMed - in process] (Source: The Open Neurology Journal)
Source: The Open Neurology Journal - February 22, 2017 Category: Neurology Tags: Open Neurol J Source Type: research

Oral and Sublingual Immunotherapy: Potential Causes for Eosinophilic Gastrointestinal Disorders?
Food allergy is a common health problem worldwide, with increasing prevalence during recent decades. The only approved treatments for food allergy are food avoidance and administration of emergency medications in case of accidental exposure, which negatively affects patients' quality of life, so new treatments are highly desirable. Different food immunotherapy modalities have recently been used, with variable success rates in the induction of desensitization and tolerance, and different numbers and types of adverse reactions. Adverse reactions, especially intolerable gastrointestinal symptoms, are the most important causes...
Source: International Archives of Allergy and Immunology - February 22, 2017 Category: Allergy & Immunology Source Type: research

Advances in the Evaluation of Respiratory Pathophysiology during Exercise in Chronic Lung Diseases
Denis E. O'Donnell, Amany F. Elbehairy, Danilo C. Berton, Nicolle J. Domnik, J. Alberto Neder (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 22, 2017 Category: Physiology Source Type: research

Lung surfactant metabolism: early in life, early in disease and target in cell therapy
AbstractLung surfactant is a complex mixture of lipids and proteins lining the alveolar epithelium. At the air –liquid interface, surfactant lowers surface tension, avoiding alveolar collapse and reducing the work of breathing. The essential role of lung surfactant in breathing and therefore in life, is highlighted by surfactant deficiency in premature neonates, which causes neonatal respiratory distress s yndrome and results in early death after birth. In addition, defects in surfactant metabolism alter lung homeostasis and lead to disease. Special attention should be paid to two important key cells responsible for surf...
Source: Cell and Tissue Research - February 22, 2017 Category: Cytology Source Type: research

Identification of host cellular proteins that interact with the M protein of a highly pathogenic porcine reproductive and respiratory syndrome virus vaccine strain
The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) continues to pose one of the greatest threats to the swine industry. M protein is the most conserved and important structura... (Source: Virology Journal)
Source: Virology Journal - February 22, 2017 Category: Virology Authors: Qian Wang, Yanwei Li, Hong Dong, Li Wang, Jinmei Peng, Tongqing An, Xufu Yang, Zhijun Tian and Xuehui Cai Source Type: research

Can body mass index predict clinical outcomes for patients with acute lung injury/acute respiratory distress syndrome? A meta-analysis
The effects of body mass index (BMI) on the prognosis of acute respiratory distress syndrome (ARDS) are controversial. We aimed to further determine the relationship between BMI and the acute outcomes of patie... (Source: Critical Care)
Source: Critical Care - February 22, 2017 Category: Intensive Care Authors: Yue-Nan Ni, Jian Luo, He Yu, Yi-Wei Wang, Yue-Hong Hu, Dan Liu, Bin-Miao Liang and Zong-An Liang Source Type: research

MERS-CoV spike nanoparticles protect mice from MERS-CoV infection.
In this study, we demonstrate protection induced by vaccination with a recombinant MERS-CoV S nanoparticle vaccine and Matrix-M1 adjuvant combination in mice. The MERS-CoV S nanoparticle vaccine produced high titer anti-S neutralizing antibody and protected mice from MERS-CoV infection in vivo. PMID: 28237499 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - February 22, 2017 Category: Allergy & Immunology Authors: Coleman CM, Venkataraman T, Liu YV, Glenn GM, Smith GE, Flyer DC, Frieman MB Tags: Vaccine Source Type: research

Role of ROCK Isoforms in Regulation of Stiffness Induced Myofibroblast Differentiation in Lung Fibrosis.
Abstract Fibrosis is a major cause of progressive organ dysfunction in several chronic pulmonary diseases. Rho associated coiled-coil forming kinase (ROCK) has shown to be involved in myofibroblast differentiation driven by altered matrix stiffness in fibrotic state. There are two known ROCK isoforms in human, ROCK1 (ROKβ) and ROCK2 (ROKα), but specific role of each isoform in myofibroblast differentiation in lung fibrosis remains unknown. To study this, we developed a Gelatin methacryloyl (GelMA) hydrogel based culture system with different stiffness levels relevant to healthy and fibrotic lungs. We have shown ...
Source: Am J Respir Cell Mol... - February 22, 2017 Category: Respiratory Medicine Authors: Htwe SS, Cha BH, Yue K, Khademhosseini A, Knox AJ, Ghaemmaghami AM Tags: Am J Respir Cell Mol Biol Source Type: research

Respiratory Care Gibson Vanessa and Waters David (Eds) Respiratory Care 282pp £25.99 CRC Press 9781482248708 1482248700 [Formula: see text].
Authors: Abstract The editors have compiled this book as a student primer on respiratory care. It covers the subject in 21 chapters and will be useful as a single introductory textbook. PMID: 28224863 [PubMed - in process] (Source: Nursing Standard)
Source: Nursing Standard - February 22, 2017 Category: Nursing Tags: Nurs Stand Source Type: research

Impact of the 2014 American Academy of Pediatrics guidance on respiratory syncytial virus and bronchiolitis hospitalization rates for infants born prematurely
Rajah et  al1 analyzed data on patients hospitalized for the respiratory syncytial virus (RSV) during 2 RSV seasons, the year before and the year after the American Academy of Pediatrics issued new, more restrictive guidance on the use of palivizumab.2 They infer that these differences were due to the adopt ion of this guidance. Problems with inferring causation from their data include the lack of a denominator to determine hospitalization rates, expected year-to-year variation in illness severity, failure to examine changes in hospitalizations for non-RSV bronchiolitis, and failure to adjust for the i mpact of multiple c...
Source: The Journal of Pediatrics - February 22, 2017 Category: Pediatrics Authors: Harold J. Farber Tags: Letters to the Editor Source Type: research

Reply
We read with interest the comments from Farber, who suggested that based on the data that we reported, an increase in the rates on hospitalizations for respiratory syncytial virus (RSV) could not be determined. We certainly agree with this comment, because we did not have the denominator and thus hospitalization rates for RSV were not estimated. Instead, we observed among all hospitalized infants with RSV infection, that the proportion of infants born prematurely at 290/7-346/7 weeks of gestation who were   (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - February 22, 2017 Category: Pediatrics Authors: Asuncion Mejias, Pablo J. S ánchez, Octavio Ramilo Tags: Letters to the Editor Source Type: research

Optimal Management of a Synchronous Diagnosis of Phaeochromocytoma and Colorectal Neoplasia
We report on treatment strategies and clinical outcomes in a series of patients with colorectal neoplasia and phaeochromocytoma. Demographic and clinical details of four patients over a 4-year period were reviewed. The median (range) age at first presentation was 66 (52 –70) years. Phaeochromocytoma (2.5–12.5 cm) was confirmed on biochemistry after incidental detection of an adrenal mass on CT scan—three had CT for staging of CRC and one had CT scan for weight loss. Adrenalectomy (three retroperitoneoscopic and one open procedure) was first performed after m aximally tolerated alpha blockade; no significant complica...
Source: Indian Journal of Surgical Oncology - February 22, 2017 Category: Cancer & Oncology Source Type: research

Nosocomial Outbreak of Drug-Resistant Streptococcus pneumoniae Serotype 9V in an Adult Respiratory Medicine Ward [Epidemiology]
Streptococcus pneumoniae infections arising in hospitalized patients are often assumed to be sporadic and linked to community acquisition. Here, whole-genome sequencing was used to demonstrate nosocomial acquisition of antimicrobial-resistant sequence type 156 (ST156) serotype 9V S. pneumoniae in 3 respiratory patients that resulted in two bacteremias and one lower respiratory tract infection. Two of the cases arose in patients who had recently been discharged from the hospital and were readmitted from the community. Nosocomial spread was suspected solely because of the highly unusual resistance pattern and case presentati...
Source: Journal of Clinical Microbiology - February 22, 2017 Category: Microbiology Authors: Jauneikaite, E., Khan-Orakzai, Z., Kapatai, G., Bloch, S., Singleton, J., Atkin, S., Shah, V., Hatcher, J., Samarasinghe, D., Sheppard, C., Fry, N. K., Satta, G., Sriskandan, S. Tags: Epidemiology Source Type: research

A Unique Capsule Locus in the Newly Designated Actinobacillus pleuropneumoniae Serovar 16 and Development of a Diagnostic PCR Assay [Clinical Veterinary Microbiology]
Actinobacillus pleuropneumoniae causes pleuropneumonia, an economically significant lung disease of pigs. Recently, isolates of A. pleuropneumoniae that were serologically distinct from the previously characterized 15 serovars were described, and a proposal was put forward that they comprised a new serovar, serovar 16. Here we used whole-genome sequencing of the proposed serovar 16 reference strain A-85/14 to confirm the presence of a unique capsular polysaccharide biosynthetic locus. For molecular diagnostics, primers were designed from the capsule locus of strain A-85/14, and a PCR was formulated that differentiated sero...
Source: Journal of Clinical Microbiology - February 22, 2017 Category: Microbiology Authors: Bosse, J. T., Li, Y., Sarközi, R., Gottschalk, M., Angen, O., Nedbalcova, K., Rycroft, A. N., Fodor, L., Langford, P. R. Tags: Clinical Veterinary Microbiology Source Type: research

Healthcare professionals ’ accounts of challenges in managing motor neurone disease in primary healthcare: a qualitative study
Abstract Motor neurone disease (MND) is a progressive neurological disease causing muscle wasting, gradual paralysis and respiratory failure, with a life expectancy of 2–4 years. In order to better understand how MND is managed in the community, we conducted a qualitative study to explore the challenges healthcare professionals encounter when managing MND in primary healthcare. Based on data from 15 semi‐structured interviews with primary healthcare professionals in Norway, we found that MND is viewed as a condition that requires exceptional effort and detailed planning. Healthcare professionals reported five main cha...
Source: Health and Social Care in the Community - February 22, 2017 Category: Health Management Authors: Sverre Vigeland Lerum, Kari Nyheim Solbr ække, Jan C. Frich Tags: Original Article Source Type: research

Parents' perceptions of healthcare providers' caring: Nothing is too small for parents and children with congenital heart disease hospitalized for heart surgery
Conclusions Healthcare providers play an irreplaceable role in alleviating parents’ emotional toll when their child undergoes cardiac surgery. Providers’ caring is an integral component in healthcare. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - February 22, 2017 Category: Respiratory Medicine Source Type: research

Mortality among high-risk patients admitted with septic shock to U.S. teaching hospitals in July: Does the ‘July Effect’ exist?
Conclusion Similar trends in mortality are observed in both settings in May and July and no “July effect” was observed. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - February 22, 2017 Category: Respiratory Medicine Source Type: research

Linshom thermodynamic sensor is a reliable alternative to capnography for monitoring respiratory rate
This study demonstrated a promising correlation between the LRMD and capnography for use as a respiratory rate monitor. The LRMD technology may be a significant addition to monitoring vital signs because it offers a minimally intrusive opportunity to detect respiratory rate and apnea, without expensive or complex anesthetic equipment, before the need for life-saving resuscitation arises. (Source: Journal of Clinical Monitoring and Computing)
Source: Journal of Clinical Monitoring and Computing - February 22, 2017 Category: Information Technology Source Type: research

Cardiorespiratory instability in monitored step-down unit patients: using cluster analysis to identify patterns of change
AbstractCardiorespiratory instability (CRI) in monitored step-down unit (SDU) patients has a variety of etiologies, and likely manifests in patterns of vital signs (VS) changes. We explored use of clustering techniques to identify patterns in the initial CRI epoch (CRI1; first exceedances of VS beyond stability thresholds after SDU admission) of unstable patients, and inter-cluster differences in admission characteristics and outcomes. Continuous noninvasive monitoring of heart rate (HR), respiratory rate (RR), and pulse oximetry (SpO2) were sampled at 1/20  Hz. We identified CRI1 in 165 patients, employed hierarchical an...
Source: Journal of Clinical Monitoring and Computing - February 22, 2017 Category: Information Technology Source Type: research

Nasal Anatomy and Function
Facial plast Surg 2017; 33: 003-008 DOI: 10.1055/s-0036-1597950The nose is a complex structure important in facial aesthetics and in respiratory physiology. Nasal defects can pose a challenge to reconstructive surgeons who must re-create nasal symmetry while maintaining nasal function. A basic understanding of the underlying nasal anatomy is thus necessary for successful nasal reconstruction. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Facial Plastic Surgery)
Source: Facial Plastic Surgery - February 22, 2017 Category: Cosmetic Surgery Authors: Patel, Ruchin G. Tags: Review Article Source Type: research

IJERPH, Vol. 14, Pages 217: Comparison of Influenza Epidemiological and Virological Characteristics between Outpatients and Inpatients in Zhejiang Province, China, March 2011–June 2015
Given the rapid rate of global spread and consequently healthcare costs related to influenza, surveillance plays an important role in monitoring the emerging pandemics in China. However,  the characteristics of influenza in Southeast of China haven’t been fully studied. Our study use the surveillance data collected from 16 sentinel hospitals across Zhejiang Province during March 2011 through June 2015, including the demographic information and respiratory specimens from influenza -like illness (ILI) patients and severe acute respiratory illness (SARI) patients. As analysis results, most SARI and ILI patients were in the...
Source: International Journal of Environmental Research and Public Health - February 22, 2017 Category: Environmental Health Authors: Wei Cheng Zhao Yu Shelan Liu Xueying Zhang Xiaoxiao Wang Jian Cai Feng Ling Enfu Chen Tags: Article Source Type: research

Rigid spine syndrome associated with sensory ‐motor axonal neuropathy resembling Charcot‐Marie‐Tooth disease is characteristic of BAG3 gene mutations even without cardiac involvement
This article is protected by copyright. All rights reserved. (Source: Muscle and Nerve)
Source: Muscle and Nerve - February 22, 2017 Category: Internal Medicine Authors: Jean ‐Baptiste Noury, Thierry Maisonobe, Pascale Richard, Valérie Delague, Edoardo Malfatti, Tanya Stojkovic Tags: Short Report Source Type: research

Pulmonary haemodynamics and gasometric parameters associated with exercise induced oxygen desaturation in idiopathic pulmonary fibrosis
Conclusion Exercise induced oxygen desaturation in IPF can be predicted from PFTs and haemogasometric parameters. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - February 22, 2017 Category: Respiratory Medicine Source Type: research

A targeted approach toward more accurate assessment of hypertension
Publication date: Available online 21 February 2017 Source:Egyptian Journal of Chest Diseases and Tuberculosis Author(s): Dina Johar, Larry Bernstein There is neither a unifying concept nor a sufficient multivariable approach to apply the use of laboratory markers to clinical practice with respect to the metabolic syndrome. The relationship of metabolic syndrome to the development of hypertension and the concurrent development of chronic renal disease has become evident. We have shown biomarkers to have significant value in combination for assessing heart failure and pulmonary hypertension. The pathogenesis of hypertensio...
Source: Egyptian Journal of Chest Diseases and Tuberculosis - February 22, 2017 Category: Respiratory Medicine Source Type: research

Greater endurance capacity and improved dyspnoea with acute oxygen supplementation in idiopathic pulmonary fibrosis patients without resting hypoxaemia
ConclusionIn patients with IPF, breathing oxygen at FiO2 of 0.50 at rest seems safe. During exercise, oxygen improves exercise tolerance, alleviates exercise‐induced hypoxaemia and reduces dyspnoea. A potential relationship between oxygen administration and improved skeletal muscle metabolism should be explored in future studies. (Source: Respirology)
Source: Respirology - February 22, 2017 Category: Respiratory Medicine Authors: Leona M. Dowman, Christine F. McDonald, Steven Bozinovski, Ross Vlahos, Rebecca Gillies, Dodie Pouniotis, Catherine J. Hill, Nicole S.L. Goh, Anne E Holland Tags: Original Article Source Type: research

A 7 ‐year follow‐up study of obstructive sleep apnoea in healthy elderly: The PROOF cohort study
ConclusionsIn elderlies, the severity and prevalence of OSA decrease progressively with ageing without effect of factors commonly influencing OSA severity. This trend may support the hypothesis that in healthy elderly, OSA is a phenomenon related to ageing. (Source: Respirology)
Source: Respirology - February 22, 2017 Category: Respiratory Medicine Authors: Emilia Sforza, David Hupin, Vincent Pichot, Jean Claude Barth élémy, Frédéric Roche Tags: Original Article Source Type: research

A histologically proven case of lymphocytic interstitial pneumonia in a HIV infected adult with an undetectable viral load
Publication date: Available online 21 February 2017 Source:Respiratory Medicine Case Reports Author(s): Sarah Assaf, Pujan Patel, David Stoeckel Lymphocytic interstitial pneumonia (LIP) is on the spectrum of lymphoproliferative diseases that can affect the lungs. Although common in human immunodeficiency virus (HIV) infected children, it is rarely reported in adults. A 51-year-old HIV infected female patient presented with worsening dyspnea over five months. She had radiological findings of bilateral lung nodular infiltrates. Her CD4 count was 835 cells/uL and her HIV viral load was undetectable. Bronchoalveolar lavage d...
Source: Respiratory Medicine Case Reports - February 22, 2017 Category: Respiratory Medicine Source Type: research

Epithelial and endothelial cell plasticity in chronic obstructive pulmonary disease (COPD)
Publication date: Available online 21 February 2017 Source:Respiratory Investigation Author(s): Sukhwinder Singh Sohal Chronic Obstructive Pulmonary Disease (COPD) is mainly caused by smoking and presents with shortness of breath that is progressive and irreversible. It is a worldwide health problem and the fourth most common cause of chronic disability and mortality (even in developed countries). It is a complex disease involving both the airway and lung parenchyma. Small-airway fibrosis is the main contributor to physiological airway dysfunction in COPD. One potential mechanism contributing to small-airway fibrosis is e...
Source: Respiratory Investigation - February 22, 2017 Category: Respiratory Medicine Source Type: research

Optimal flow rate sampling designs for studies with extended exhaled nitric oxide analysis
Introduction. The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation. Repeat FeNO maneuvers at multiple fixed exhalation flow rates (extended NO analysis) can be used to estimate parameters quantifying proximal and distal sources of NO in mathematical models of lower respiratory tract NO. A growing number of studies use extended NO analysis, but there is no official standard flow rate sampling protocol. In this paper, we provide information for study planning by deriving theoretically optimal flow rate sampling designs. Methods . First, we reviewed previously published desig...
Source: Journal of Breath Research - February 22, 2017 Category: Respiratory Medicine Authors: Noa Molshatski and Sandrah P Eckel Source Type: research

A ırway and sleep dısorders ın patıents wıth acromegaly
CONCLUSION: SDB seems to be common and clinically important in patients with acromegaly,particularly in men. The most frequent type of apnea in acromegalics is obstructive.Hormonal activity of acromegaly does not seem to have an effect on the development of SAS. Despite its high prevalence,SAS is frequently under‐assessed in patients with acromegaly.Systemic complications and SDB should be researched in acromegalics. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 22, 2017 Category: Respiratory Medicine Authors: Onur Turan, Bar ış Akıncı, Ahmet Omer Ikız, Oya Itıl, Ibrahim Oztura, Emel Ada, Bahri Akdenız, Serkan Yener, Murat Kaya, Arzu Gedık, Abdurrahman Comlekcı Tags: Original Article Source Type: research

Impacts of disease severity on postoperative complications in children with sleep ‐disordered breathing
ConclusionsChildren with severe OSA have increased risks of perioperative respiratory complications. However, OSA severity does not influence major respiratory complications or postoperative bleeding in children. Level of Evidence4 Laryngoscope, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - February 22, 2017 Category: ENT & OMF Authors: Kun ‐Tai Kang, I‐Sheng Chang, Chia‐Chen Tseng, Wen‐Chin Weng, Tzu‐Yu Hsiao, Pei‐Lin Lee, Wei‐Chung Hsu Tags: Pediatrics Source Type: research

Pepsin as a biomarker for laryngopharyngeal reflux in children with laryngomalacia
ConclusionsPepsin in supraglottic specimens demonstrated an association with laryngomalacia, supporting a role for refluxed pepsin in laryngomalacia. These data corroborate previous work implicating pepsin in inflammatory diseases of the upper airways. Further studies are warranted to investigate the contribution of pepsin to the pathophysiology of laryngomalacia. Level of Evidence3b. Laryngoscope, 2017 (Source: The Laryngoscope)
Source: The Laryngoscope - February 22, 2017 Category: ENT & OMF Authors: Kendra Luebke, Tina L. Samuels, Thomas H. Chelius, Cecille G. Sulman, Michael E. McCormick, Joseph E. Kerschner, Nikki Johnston, Robert H. Chun Tags: Pediatrics Source Type: research

Effect of dezocine combined with propofol on painless gastroscopy in patients with suspect gastric carcinoma
Conclusion: Dezocine combined with propofol on painless gastroscopy can reduce the respiratory depression and body movement without interference of hemodynamics. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - February 22, 2017 Category: Cancer & Oncology Authors: Ji Ma Peng Zhang Yixuan Zhang Zong Chen Wenqi Xin Donghang Zhang Chuangeng Ma Source Type: research

Feasibility of multiple breath washout measurements in infants with bronchiolitis: A pilot study
CONCLUSIONMBW measurements during natural sleep are feasible but technically challenging in infants with acute bronchiolitis. LCI is raised compared to healthy controls. Larger trials, possibly using sedation protocols and shortened washout periods, are required to corroborate these findings. LCI can potentially serve as an objective indicator of severity and could be considered as a biomarker for future interventional trials. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - February 21, 2017 Category: Respiratory Medicine Authors: Patrick Stafler, Sigal Weinreb, Huda Mussaffi, Meir Mei ‐Zahav, Dario Prais, Guy Steuer, Ophir Bar‐On, Moshe Hoshen, Hannah Blau Tags: ORIGINAL ARTICLE Source Type: research

Whole-Body MRI Virtual Autopsy Using Diffusion-weighted Imaging With Background Suppression (DWIBS) at 3 T in a Child Succumbing to Chordoma
Conclusions: Postmortem virtual MRI autopsy including DWIBS successfully demonstrated the transthoracic spread of chordoma and invasion of the heart, resulting in blood-borne metastases. Motion and respiratory artifact were not factors during virtual autopsy using DWIBS on 3 T, making ideal use of this technology. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 21, 2017 Category: Hematology Tags: Radiology Corner Source Type: research