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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.

Factors associated with overestimation of asthma control: a cross-sectional study in Australia.
CONCLUSIONS: Overestimation of asthma control remains a significant issue in Australians with asthma. The study highlights the importance of encouraging patients to express their feelings about asthma control and beliefs about medicines, and to be more forthcoming with their asthma symptoms. This would help to reveal any discrepancies between perceived and actual asthma control. PMID: 27603169 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - September 8, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Breastfeeding and Timing of First Dietary Introduction in Relation to Childhood Asthma, Allergies, and Airway Diseases: A Cross-sectional Study.
CONCLUSIONS: This study suggests that heredity, but not sex and socioeconomic status, may negatively impact the effect of BF on childhood airway and allergic diseases. Our findings support China's national recommendation that mothers provide exclusive BF for the first four months, and continue partial BF for more than six months. PMID: 27603296 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - September 8, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

The aetiology of diarrhoea, pneumonia and respiratory colonization of HIV-exposed infants randomized to breast- or formula-feeding.
CONCLUSION: A trend toward oropharyngeal bacterial colonization was observed in formula-fed infants. Although viruses were most commonly detected during pneumonia, respiratory colonization by Gram-negative bacteria may have contributed to pneumonia in formula-fed infants. PMID: 27595698 [PubMed - in process] (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - September 8, 2016 Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research

In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity.
In conclusion, the use of these botanicals was shown to be able to contrast OTC-toxicity and could represent a new approach for the development of functional foods useful to enhance the standard pharmacological treatment in infections as well as in preventing or reducing the emergence of inflammatory diseases. PMID: 27597982 [PubMed - in process] (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - September 8, 2016 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Technical Note: A respiratory monitoring and processing system based on computer vision: prototype and proof of principle
Monitoring and controlling respiratory motion is a challenge for the accuracy and safety of therapeutic irradiation of thoracic tumors. Various commercial systems based on the monitoring of internal or external surrogates have been developed but remain costly. In this article we describe and validate Madibreast, an in-house-made respiratory monitoring and processing device based on optical tracking of external markers. We designed an optical apparatus to ensure real-time submillimetric image resolution at 4 m. Using OpenCv libraries, we optically tracked high-contrast markers set on patients ’ breasts. Validation of spat...
Source: Journal of Applied Clinical Medical Physics - September 8, 2016 Category: Physics Source Type: research

Fat Embolism Syndrome Secondary to Bone Marrow Necrosis in Patients with Hemoglobinopathies.
Authors: Gangaraju R, Reddy VV, Marques MB Abstract Bone marrow necrosis with subsequent embolization of the fat and necrotic tissues into the systemic circulation causing fat embolism syndrome and multiorgan failure is a rare complication of patients with hemoglobinopathies. The exact etiology of this condition is not known. Because it occurs more often in patients with compound heterozygous conditions than in sickle cell disease, some patients are unaware of their predisposition. The initial symptoms are nonspecific, such as back and/or abdominal pain, fever, and fatigue, which may rapidly progress to respiratory...
Source: Southern Medical Journal - September 8, 2016 Category: Journals (General) Tags: South Med J Source Type: research

Detection and molecular characterization of porcine reproductive and respiratory syndrome virus in Lithuanian wild boar populations
Porcine reproductive and respiratory syndrome virus (PRRSV) is recognized worldwide as an important and economically devastating pathogen in pig production. Although PRRSV is widespread in domestic swine, ther... (Source: Acta Veterinaria Scandinavica)
Source: Acta Veterinaria Scandinavica - September 8, 2016 Category: Veterinary Research Authors: Arunas Stankevicius, Jurate Buitkuviene, Virginija Sutkiene, Ugne Spancerniene, Ina Pampariene, Arnoldas Pautienius, Vaidas Oberauskas, Henrikas Zilinskas and Judita Zymantiene Source Type: research

Skeletal Muscle Alterations Are Exacerbated in Heart Failure With Reduced Compared With Preserved Ejection Fraction: Mediated by Circulating Cytokines? [Original Article]
Conclusions— Our findings suggest, for the first time, that skeletal muscle alterations are exacerbated in HFrEF compared with HFpEF, which predominantly reside in limb, rather than in respiratory, muscle. This disparity may be mediated, in part, by the different circulating inflammatory cytokines that were elevated between HFpEF and HFrEF. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 8, 2016 Category: Cardiology Authors: Seiler, M., Bowen, T. S., Rolim, N., Dieterlen, M.-T., Werner, S., Hoshi, T., Fischer, T., Mangner, N., Linke, A., Schuler, G., Halle, M., Wisloff, U., Adams, V. Tags: Basic Science Research, Growth Factors/Cytokines, Oxidant Stress, Pathophysiology, Heart Failure Original Article Source Type: research

Comparative Effectiveness of Pharmacological Interventions for Pulmonary Arterial Hypertension: A Systematic Review and Network Meta-Analysis.
CONCLUSIONS: Currently approved pharmacological agents have varying effects on morbidity and functional status in patients with PAH. Future comparative effectiveness trials are warranted with a focus on patient-centered approach to therapy. PMID: 27615023 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - September 8, 2016 Category: Respiratory Medicine Authors: Jain S, Khera R, Girotra S, Badesch D, Wang Z, Murad MH, Blevins A, Schmidt GA, Singh S, Gerke AK Tags: Chest Source Type: research

Culture Negative Severe Sepsis - Nationwide Trends and Outcomes.
CONCLUSIONS: CNSS among hospitalized patients is common, and its proportion is on the rise. CNSS is associated with greater acute organ dysfunctions and mortality. Being culture negative is an independent predictor of death. PMID: 27615024 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - September 8, 2016 Category: Respiratory Medicine Authors: Gupta S, Sakhuja A, Kumar G, McGrath E, Nanchal RS, Kashani KB Tags: Chest Source Type: research

Mucilaginibacter antarcticus sp. nov., isolated from Antarctica South Shetland Islands soil.
Abstract The novel pale yellow-coloured bacterial strain, designated S14-88T, was isolated from a tundra soil near Antarctic Peninsula, South Shetland Islands (62° 22' 34" S, 59° 42' 34" W), and the taxonomic position was investigated by a genotypic and phenotypic analysis. The cells were facultatively anaerobic, Gram-staining-negative, non-motile and rod-shaped. Growth occurred at 4-28 ℃ (optimum at 15 ℃), at pH 7.0-8.0 (optimum at 7.0), and with 0-0.6 % (w/v) NaCl (optimum, no NaCl). Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain S14-88T formed a lineage within the genus Mucil...
Source: International Journal of Systematic and Evolutionary Microbiology - September 8, 2016 Category: Microbiology Authors: Zheng R, Zhao Y, Wang L, Chang X, Zhang Y, Da X, Peng F Tags: Int J Syst Evol Microbiol Source Type: research

Rufibacter quisquiliarum sp. nov., a new member of the phylum Bacteroidetes isolated from a bioreactor treating landfill leachate.
Abstract A new bacterium, CAI-18bT, was isolated from a bioreactor that treated landfill leachate using an oligotrophic growth medium. Phylogenetic analysis based on the 16S rRNA gene revealed that strain CAI-18bT is a member of the genus Rufibacter, showing 97.1% pairwise similarity value to Rufibacter roseus H359T, 96.4% to Rufibacter tibetensis 1351T, 96.4% to Rufibacter glacialis MDT1-10-3T and 96.0% to Rufibacter immobilis MCC P1T. Strain CAI-18bT was rod-shaped, motile, oxidase and catalase positive. The predominant fatty acids were iso-C15:0 (24.1%) and iso-C17:1 I (22.3%), the major respiratory quinone was...
Source: International Journal of Systematic and Evolutionary Microbiology - September 8, 2016 Category: Microbiology Authors: Felfoldi T, Mentes A, Schumann P, Kéki Z, Máthé I, Márialigeti K, Tóth EM Tags: Int J Syst Evol Microbiol Source Type: research

Oxygen therapy in COPD patients with isolated nocturnal hypoxemia; comparison of quality of life and sleep between bronchitis and emphysema phenotype: A prospective observational study.
CONCLUSIONS: Six months of nO2LT improve quality of life in COPDe, not in COPDb. We found a difference in sleep quality between COPDe and COPDb. PMID: 27614376 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 8, 2016 Category: Internal Medicine Authors: Rizzi M, Airoldi A, Cristiano A, Frassanito F, Macaluso C, Vanni S, Legnani D Tags: Eur J Intern Med Source Type: research

Risks of Death and Severe Disease in Patients With Middle East Respiratory Syndrome Coronavirus, 2012-2015.
This study represents an attempt to estimate risk factors for an emerging infectious disease using open data and to address some of the uncertainty surrounding MERS-CoV epidemiology. PMID: 27608662 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - September 8, 2016 Category: Epidemiology Authors: Rivers CM, Majumder MS, Lofgren ET Tags: Am J Epidemiol Source Type: research

Oral health education (advice and training) for people with serious mental illness.
CONCLUSIONS: We found no evidence from trials that oral health advice helps people with serious mental illness in terms of clinically meaningful outcomes. It makes sense to follow guidelines and recommendations such as those put forward by the British Society for Disability and Oral Health working group until better evidence is generated. Pioneering trialists have shown that evaluative studies relevant to oral health advice for people with serious mental illness are possible. PMID: 27606629 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - September 8, 2016 Category: Journals (General) Authors: Khokhar MA, Khokhar WA, Clifton AV, Tosh GE Tags: Cochrane Database Syst Rev Source Type: research

Induction of Pulmonary Granuloma Formation by Propionibacterium acnes is regulated by MyD88 and Nox2.
In conclusion, we have generated a mouse model of early granuloma formation induced by a clinically relevant strain of P. acnes isolated from a sarcoidosis patient, and using this model we have shown that deficiency of MyD88 or CybB are associated with impaired bacterial clearance and increased granuloma formation in the lung. PMID: 27607191 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - September 8, 2016 Category: Molecular Biology Authors: Werner JL, Escolero SG, Hewlett JT, Mak TN, Williams BP, Eishi Y, Núñez G Tags: Am J Respir Cell Mol Biol Source Type: research

New indication for antibiotic
Merial Animal Health reports that Zactran, which contains the macrolide antibiotic gamithromycin, is now indicated for use in the treatment of respiratory disease in pigs associated with Actinobacillus pleuropneumoniae, Haemophilus parasuis and Pasteurella multocida. Noting that respiratory disease is a significant problem for the pig industry, the company says that gamithromycin accumulates in target lung tissue in less than 30 minutes and reaches and exceeds the minimum bactericidal concentration for the relevant pathogens for an extended period. This, it says, helps to relieve clinical signs and minimise lung damage. Th...
Source: Veterinary Record - September 8, 2016 Category: Veterinary Research Tags: Products and Services Source Type: research

IJERPH, Vol. 13, Pages 895: Cotton Dust Exposure and Respiratory Disorders among Textile Workers at a Textile Company in the Southern Part of Benin
The objective of the study was to evaluate the respiratory disorders among the textile workers exposed to cotton dust and the cross-sectional study involved 656 subjects exposed to cotton dust and 113 non-exposed subjects. The methods used are mainly based on a survey using a questionnaire of organic dust designed by the International Commission of Occupational Health (ICOH); and on the measures of lung function parameters (FEV1 and FVC). The main results of the different analyzes revealed that subjects exposed to cotton dust have more respiratory symptoms than unexposed subjects (36.9% vs. 21.2%). The prevalence of chroni...
Source: International Journal of Environmental Research and Public Health - September 8, 2016 Category: Environmental Health Authors: Antoine Hinson Virgil Lokossou Vivi Schl ünssen Gildas Agodokpessi Torben Sigsgaard Benjamin Fayomi Tags: Article Source Type: research

11q terminal deletion and combined immunodeficiency (Jacobsen syndrome): Case report and literature review on immunodeficiency in Jacobsen syndrome
Antibody deficiency is common finding in patients with Jacobsen syndrome (JS). In addition, there have been few reports of T‐cell defects in this condition, possibly because most of the reported patients have not been specifically evaluated for T‐cell function. In this article, we present a child with an 11q deletion and combined immunodeficiency and we perform a literature overview on immunodeficiency in JS. Our patient presented with recurrent bacterial and prolonged viral infections involving the respiratory system, as well as other classic features of the syndrome. In addition to low IgM, IgG4, and B‐cells, also ...
Source: American Journal of Medical Genetics Part A - September 8, 2016 Category: Genetics & Stem Cells Authors: Štefan Blazina, Alojz Ihan, Luca Lovrečić, Tinka Hovnik Tags: Clinical Report Source Type: research

Vesicourethral reflux ‐induced renal failure in a patient with ICF syndrome due to a novel DNMT3B mutation
This report expands the mutation spectrum of ICF1 and is the first to describe bilateral vesicoureteral reflux accompanying ICF syndrome. © 2016 Wiley Periodicals, Inc. (Source: American Journal of Medical Genetics Part A)
Source: American Journal of Medical Genetics Part A - September 8, 2016 Category: Genetics & Stem Cells Authors: Seyhan Kutlu ğ, Gönül Ogur, Aysegül Yilmaz, Peter E. Thijssen, Ummet Abur, Alisan Yildiran Tags: Clinical Report Source Type: research

Molecular Genetic Analysis of Chlamydia Species.
Abstract Species of Chlamydia are the etiologic agent of endemic blinding trachoma, the leading cause of bacterial sexually transmitted diseases, significant respiratory pathogens, and a zoonotic threat. Their dependence on an intracellular growth niche and their peculiar developmental cycle are major challenges to elucidating their biology and virulence traits. The last decade has seen tremendous advances in our ability to perform a molecular genetic analysis of Chlamydia species. Major achievements include the generation of large collections of mutant strains, now available for forward- and reverse-genetic appli...
Source: Annual Review of Microbiology - September 8, 2016 Category: Microbiology Authors: Sixt BS, Valdivia RH Tags: Annu Rev Microbiol Source Type: research

Low Beta-Adrenergic Sweat Reponses in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator-Related Metabolic Syndrome Children
Pediatric Allergy, Immunology, and Pulmonology , Vol. 0, No. 0. (Source: Pediatric, Allergy, Immunology, and Pulmonology)
Source: Pediatric, Allergy, Immunology, and Pulmonology - September 8, 2016 Category: Respiratory Medicine Authors: Danieli Barino Salinas Lucia Kang Colleen Azen Paul Quinton Source Type: research

Cystic Benign Metastasizing Leiomyoma of the Lung Mimicking Hydatid Cyst
AbstractA 60-year-old woman, with history of a resected uterine benign leiomyoma, is operated for a cystic lesion in the left lung, mimicking an hydatid cyst, and confirmed histologically as Cystic Benign Metastasizing Leiomyoma. (Source: Lung)
Source: Lung - September 8, 2016 Category: Respiratory Medicine Source Type: research

Relationship between chronic kidney disease and central sleep apnea: the importance of volume management
(Source: Sleep and Breathing)
Source: Sleep and Breathing - September 8, 2016 Category: Respiratory Medicine Source Type: research

Probing the prevalence of central sleep apnea in patients with chronic kidney disease
(Source: Sleep and Breathing)
Source: Sleep and Breathing - September 8, 2016 Category: Respiratory Medicine Source Type: research

Central retinal artery occlusion, an early sign of crizotinib resistance in an alk positive adenocarcinoma of lung: A rare case report
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 8, 2016 Category: Respiratory Medicine Authors: Irappa Madabhavi, Apurva Patel, Asha Anand, Harsha Panchal, Sonia Parikh Tags: Letter to the Editor Source Type: research

Application of a Parametric Model in the Mortality Risk Analysis of ICU Patients with Severe COPD
Conclusion: Formula generated from parametric model may help to predict the prognosis of patients with severe COPD in ICU, and this method need to be evaluated in further studies. According to our formula, IPA is an important risk factor of mortality for patients with severe COPD in the ICU. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 8, 2016 Category: Respiratory Medicine Authors: Hangyong He, Ying Sun, Bing Sun, Qingyuan Zhan Tags: Original Article Source Type: research

Study on small airway function in asthmatics with fractional exhaled nitric oxide and impulse oscillometry
Conclusion: FeNO and IOS are helpful in diagnosis of small airway dysfunction with high sensitivity and specificity, and FeNO combined with IOS can better evaluate the small airway function in asthmatic patients. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 8, 2016 Category: Respiratory Medicine Authors: Lin Liu, Wen Liu, Chunhong Liu, Dexiang Wang, Jiping Zhao, Junfei Wang, Jinxiang Wu, Tian Liu, Yuanyuan Zhang, Yahui Liu, Liuzhao Cao, Liang Dong Tags: Original Article Source Type: research

Managing Respiratory Failure in Obstructive Lung Disease
Exacerbations of obstructive lung disease are common causes of acute respiratory failure. Short-acting bronchodilators and systemic glucocorticoids are the foundation of pharmacologic management. For patients requiring ventilator support, use of noninvasive ventilation reduces the risk of mortality and progression to invasive mechanical ventilation. Challenges associated with invasive ventilation include ventilator dyssynchrony, air trapping, and dynamic hyperinflation. Careful monitoring and adjustment of ventilatory support parameters helps to optimize the patient –ventilator interaction and minimizes the risk of assoc...
Source: Clinics in Chest Medicine - September 8, 2016 Category: Respiratory Medicine Authors: Stephen P. Bergin, Craig R. Rackley Source Type: research

OP21.04: Ultrasound guided intra ‐amniotic instillation of surfactant before preterm delivery for prevention of neonatal respiratory syndrome: a novel approach
(Source: Ultrasound in Obstetrics and Gynecology)
Source: Ultrasound in Obstetrics and Gynecology - September 8, 2016 Category: Radiology Authors: N. Agarwal, S. Bathwal, A. Kriplani, A. Deorari, N. Bhatla Tags: Abstracts Source Type: research

Independent effect of prior exacerbation frequency and disease severity on the risk of future exacerbations of COPD: a retrospective cohort study
npj Primary Care Respiratory Medicine, Published online: 8 September 2016; doi:10.1038/npjpcrm.2016.46 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - September 8, 2016 Category: Primary Care Authors: Miguel Santiba ñez Margüello Roberto Garrastazu Mario Ruiz-Nu ñez Jose Manuel Helguera Sandra Arenal Cristina Bonnardeux Carlos Le ón Marc Miravitlles Juan Luis Garc ía-Rivero Source Type: research

Kawasaki disease associated with Mycoplasma pneumoniae
ConclusionsMP infections are found in an important proportion of the KD patients (13.8  % in our series). MP infection tended to occur in older populations and with a higher rate of respiratory tract involvement in patients with KD. No statistical difference of non-responders or coronary artery lesion was found between the MP+ and MP- KD patients. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 8, 2016 Category: Pediatrics Source Type: research

Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS
Conclusions MFPI analyses suggest a nonlinear effect modification of higher PEEP ventilation by PaO2/FiO2 and oxygenation index with reduced mortality for some patients suffering from moderate ARDS. Study registration number CRD42012003129. (Source: BMJ Open)
Source: BMJ Open - September 8, 2016 Category: Journals (General) Authors: Kasenda, B., Sauerbrei, W., Royston, P., Mercat, A., Slutsky, A. S., Cook, D., Guyatt, G. H., Brochard, L., Richard, J.-C. M., Stewart, T. E., Meade, M., Briel, M. Tags: Open access, Intensive care, Respiratory medicine Research Source Type: research

Long-term health effects of the Eyjafjallajökull volcanic eruption: a prospective cohort study in 2010 and 2013
Conclusions The findings indicate that people exposed to a volcanic eruption, especially those most exposed, exhibit increased risk of certain symptoms 3–4 years after the eruption. (Source: BMJ Open)
Source: BMJ Open - September 8, 2016 Category: Journals (General) Authors: Hlodversdottir, H., Petursdottir, G., Carlsen, H. K., Gislason, T., Hauksdottir, A. Tags: Open access, Epidemiology, Occupational and environmental medicine, Public health Research Source Type: research

What is the role of a specialist regional mesothelioma multidisciplinary team meeting? A service evaluation of one tertiary referral centre in the UK
Conclusions This specialist mesothelioma multidisciplinary team meeting was effective at making diagnoses and providing recommendations for further investigations or treatment. The core requirements of a specialist mesothelioma multidisciplinary team meeting were met. The process was timely, with most outcomes returned within 2 weeks of referral. (Source: BMJ Open)
Source: BMJ Open - September 8, 2016 Category: Journals (General) Authors: Bibby, A. C., Williams, K., Smith, S., Bhatt, N., Maskell, N. A. Tags: Open access, Medical management, Occupational and environmental medicine, Oncology, Respiratory medicine Research Source Type: research

Viral Load is Strongly Associated with Length of Stay in Adults Hospitalised with Viral Acute Respiratory Illness
Respiratory viruses are detectable in a large proportion of adults hospitalised with acute respiratory illness. For influenza and other viruses there is evidence that viral load and persistence are associated with certain clinical outcomes but it is not known if there is an association between viral load and hospital length of stay. (Source: Journal of Infection)
Source: Journal of Infection - September 8, 2016 Category: Infectious Diseases Authors: Tristan W. Clark, Sean Ewings, Marie-jo Medina, Sally Batham, Martin D. Curran, Surendra Parmar, Karl G. Nicholson Source Type: research

Cardiogenic Shock and Respiratory Failure in a Patient With Metastatic Melanoma Receiving Trametinib Therapy
(Source: The Oncologist)
Source: The Oncologist - September 8, 2016 Category: Cancer & Oncology Authors: Tseng, D., Mason, X. L., Neilan, T. G., Sullivan, R. J. Tags: Melanoma and Cutaneous Malignancies BRIEF COMMUNICATIONS Source Type: research

An Introduction to a Head and Neck Cancer-Specific Frailty Index and Its Clinical Implications in Elderly Patients: A Prospective Observational Study Focusing on Respiratory and Swallowing Functions
Conclusion. Pretreatment functional disabilities related to respiration and swallowing were significantly associated with early morbidity and mortality. The suggested index would be more useful for assessing frailty in elderly HNC patients. Implications for Practice: This study is the first report in terms of suggesting a new frailty index focusing on respiratory and swallowing functions in elderly patients with head and neck cancer. This study shows that functional disabilities associated with respiration and swallowing significantly affected early morbidity and mortality in these elderly patients. The head and neck canc...
Source: The Oncologist - September 8, 2016 Category: Cancer & Oncology Authors: Kwon, M., Kim, S.-A., Roh, J.-L., Lee, S.-W., Kim, S.-B., Choi, S.-H., Nam, S. Y., Kim, S. Y. Tags: Head and Neck Cancers, Geriatric Oncology Source Type: research

Transpulmonary Pressure: The Importance of Precise Definitions and Limiting Assumptions.
Abstract Recent studies applying the principles of respiratory mechanics to respiratory disease have used inconsistent and mutually exclusive definitions of the term "transpulmonary pressure." By the traditional definition, transpulmonary pressure is the pressure across the whole lung including the intrapulmonary airways, i.e., the pressure difference between the opening to the pulmonary airway and the pleural surface. However more recently, transpulmonary pressure has also been defined as the pressure across only the lung tissue, i.e., the pressure difference between the alveolar space and the pleural surface, tr...
Source: Am J Respir Crit Car... - September 8, 2016 Category: Intensive Care Authors: Loring SH, Topulos GP, Hubmayr RD Tags: Am J Respir Crit Care Med Source Type: research

Novel Blood Biomarkers Are Associated with White Matter Lesions in Fragile X- Associated Tremor/Ataxia Syndrome.
CONCLUSION: The dramatic increase in mitochondrial activity in lymphoblasts from PM carriers may represent either the early stages of disease (specific alterations in short-lived blood cells) or an activation of the lymphocytes under pathological situations. These changes may provide early, convenient blood biomarkers of clinical involvements. PMID: 27602566 [PubMed - as supplied by publisher] (Source: Neuro-Degenerative Diseases)
Source: Neuro-Degenerative Diseases - September 8, 2016 Category: Neurology Authors: Loesch DZ, Annesley SJ, Trost N, Bui MQ, Lay ST, Storey E, De Piazza SW, Sanislav O, Francione LM, Hammersley EM, Tassone F, Francis D, Fisher PR Tags: Neurodegener Dis Source Type: research

PCR Assay Based on the gyrB Gene for Rapid Identification of Acinetobacter baumannii ‐calcoaceticus Complex at Specie Level
ConclusionThese findings evidenced that the multiplex PCR of the gyrB is a feasible and simple method to identify isolates of the ABC at the species level. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - September 8, 2016 Category: Laboratory Medicine Authors: Aline B. Teixeira, Juliana Barin, Djuli M. Hermes, Afonso L. Barth, Andreza F. Martins Tags: Original Article Source Type: research

Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study.
Conclusion. It is feasible to use BIA to predict postresuscitation volume status and patient-important outcomes in septic ICU patients. Trial Registration. This trial is registered with clinicaltrials.gov NCT01379404 registered on June 7, 2011. PMID: 27597811 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - September 7, 2016 Category: Respiratory Medicine Authors: Rochwerg B, Cheung JH, Ribic CM, Lalji F, Clarke FJ, Gantareddy S, Ranganath N, Walele A, McDonald E, Meade MO, Cook DJ, Wilkieson TT, Clase CM, Margetts PJ, Gangji AS Tags: Can Respir J Source Type: research

Respirator Use in a Hospital Setting: Establishing Surveillance Metrics.
CONCLUSION: Adequate PPE supply and effective use that limit disease transmission and protect health care personnel are dependent on multiple factors associated with routine and emergency hospital practices. We developed forty-seven measures that may serve as the basis for a national PPE surveillance system, beginning with standardized measures of respirator use and supply for collection across different hospital types, sizes, and locations to inform hospitals, government agencies, manufacturers, and distributors. Despite involvement of multiple hospital stakeholders, regulatory guidance prescribes workplace practices that...
Source: Respiratory Care - September 7, 2016 Category: Respiratory Medicine Authors: Yarbrough MI, Ficken ME, Lehmann CU, Talbot TR, Swift MD, McGown PW, Wheaton RF, Bruer M, Little SW, Oke CA Tags: J Int Soc Respir Prot Source Type: research

A Comparison of Cough Assistance Techniques in Patients with Respiratory Muscle Weakness.
CONCLUSION: In patients with NMD and respiratory muscle dysfunction, MI-E alone was more effective than manual assistance following an MIC maneuver. However, MI-E used in conjunction with manual thrust improved PCF even further. PMID: 27593879 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - September 7, 2016 Category: Universities & Medical Training Authors: Kim SM, Choi WA, Won YH, Kang SW Tags: Yonsei Med J Source Type: research

Hypoalbuminemia, Low Base Excess Values, and Tachypnea Predict 28-Day Mortality in Severe Sepsis and Septic Shock Patients in the Emergency Department.
CONCLUSION: Our new nomogram is valuable in predicting the 28-day mortality of patients with severe sepsis and/or septic shock in the emergency department. Moreover, our readily available nomogram is superior to conventional scoring systems in predicting mortality. PMID: 27593863 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - September 7, 2016 Category: Universities & Medical Training Authors: Seo MH, Choa M, You JS, Lee HS, Hong JH, Park YS, Chung SP, Park I Tags: Yonsei Med J Source Type: research

Idiopathic Pulmonary Fibrosis and Emphysema: Between Scylla and Charybdis
Respiration (Source: Respiration)
Source: Respiration - September 7, 2016 Category: Respiratory Medicine Source Type: research

Endoscopic Lung Volume Reduction Using Endobronchial Valves in Patients with Severe Emphysema and Very Low FEV < sub > 1 < /sub >
Conclusions: The patients benefitted moderately from EBV treatment despite an initially low FEV1. Some patients improved remarkably. EBV treatment in patients with an FEV1≤20% of pred. is generally feasible and safe. The greatest risk is pneumothorax with prolonged chest tube duration.Respiration (Source: Respiration)
Source: Respiration - September 7, 2016 Category: Respiratory Medicine Source Type: research

Transthoracic Echocardiography and Chest Computed Tomography Arteriography in Patients with Acute Pulmonary Embolism: A Two-Year Follow-Up Study
Conclusion: Our study demonstrates that in patients with acute PE there is no relationship between the Qanadli CT obstruction index and TTE parameters on admission to the hospital. However, the occurrence of CTPH at the 24-month follow-up is associated with PH and with a high Qanadli CT obstruction index score.Respiration (Source: Respiration)
Source: Respiration - September 7, 2016 Category: Respiratory Medicine Source Type: research

Health status instruments for patients with COPD in pulmonary rehabilitation: defining a minimal clinically important difference.
Abstract The minimal clinically important difference (MCID) defines to what extent change on a health status instrument is clinically relevant, which aids scientists and physicians in measuring therapy effects. This is the first study that aimed to establish the MCID of the Clinical chronic obstructive pulmonary disease (COPD) Questionnaire (CCQ), the COPD Assessment Test (CAT) and the St George's Respiratory Questionnaire (SGRQ) in the same pulmonary rehabilitation population using multiple approaches. In total, 451 COPD patients participated in a 3-week Pulmonary Rehabilitation (PR) programme (58 years, 65% male...
Source: Primary Care - September 7, 2016 Category: Primary Care Authors: Alma H, de Jong C, Jelusic D, Wittmann M, Schuler M, Blok BF, Kocks J, Schultz K, Molen Tv Tags: NPJ Prim Care Respir Med Source Type: research

Novel Blood Biomarkers Are Associated with White Matter Lesions in Fragile X- Associated Tremor/Ataxia Syndrome
Conclusion: The dramatic increase in mitochondrial activity in lymphoblasts from PM carriers may represent either the early stages of disease (specific alterations in short-lived blood cells) or an activation of the lymphocytes under pathological situations. These changes may provide early, convenient blood biomarkers of clinical involvements.Neurodegener Dis 2017;17:22-30 (Source: Neurodegenerative Diseases)
Source: Neurodegenerative Diseases - September 7, 2016 Category: Neurology Source Type: research