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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 18.

Cancer metabolism in space and time: beyond the Warburg effect
This article is part of a Special Issue entitled Respiratory complex I, edited by Giuseppe Gasparre, Rodrigue Rossignol and Pierre Sonveaux. (Source: Biochimica et Biophysica Acta (BBA) Bioenergetics)
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - February 5, 2017 Category: Biochemistry Source Type: research

Chemotherapy and intercalated gefitinib or erlotinib in the treatment of advanced non-small-cell lung cancer.
Authors: Rossi A, La Salvia A, Di Maio M Abstract INTRODUCTION: Preclinical data showed that intercalated administration of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and chemotherapy might be effective in the treatment of advanced non-small-cell lung cancer (NSCLC). This review will summarize and discuss the clinical results available to date from prospective studies investigating this approach. Areas covered: A structured search of bibliographic databases for peer-reviewed literature and of main International meetings was undertaken, for trials testing the intercalated addition of EGF...
Source: Expert Review of Respiratory Medicine - February 4, 2017 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Allergen immunotherapy for respiratory allergic disease in Australia in 2016.
Authors: Smith WB, Kette FE PMID: 28152347 [PubMed - in process] (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - February 4, 2017 Category: Journals (General) Tags: Med J Aust Source Type: research

"J Thorac Dis"[ta]; +109 new citations
109 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J Thorac Dis"[ta] These pubmed results were generated on 2017/02/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 4, 2017 Category: Respiratory Medicine Tags: Report Source Type: research

Organizational Learning in a Cardiac Intensive Care Unit: A Learning History.
CONCLUSION: The findings validate the relationship between psychological safety and organizational learning, offer insight into how CCUs become high-reliability organizations, and provide clinical leaders with guidance for achieving high reliability in their organizations. The findings also help validate the American Association of Critical-Care Nurses position that a healthy work environment is essential to achieving clinical excellence. Critical care unit teams should use these findings as a framework for collective reflection and planning to achieve their desired future. Further research is needed to validate the applic...
Source: Dimensions in Critical Care Nursing - February 4, 2017 Category: Nursing Tags: Dimens Crit Care Nurs Source Type: research

Smoking habits in French farmers: a cross-sectional study
Farmers are exposed to multiple air contaminants that may interact with tobacco smoking in the development of respiratory diseases. Farmers are currently considered to smoke less than non-farmers, but precise ... (Source: BMC Public Health)
Source: BMC Public Health - February 4, 2017 Category: Consumer Health News Authors: Pauline Roux, Alicia Guillien, Thibaud Soumagne, Oph élie Ritter, Jean-Jacques Laplante, Cécile Travers, Jean-Charles Dalphin, Gérard Peiffer, Lucie Laurent and Bruno Degano Source Type: research

Serious fungal infections in Pakistan
AbstractThe true burden of fungal infection in Pakistan is unknown. High-risk populations for fungal infections [tuberculosis (TB), diabetes, chronic respiratory diseases, asthma, cancer, transplant and human immunodeficiency virus (HIV) infection] are numerous. Here, we estimate the burden of fungal infections to highlight their public health significance. Whole and at-risk population estimates were obtained from the WHO (TB), BREATHE study (COPD), UNAIDS (HIV), GLOBOCAN (cancer) and Heartfile (diabetes). Published data from Pakistan reporting fungal infections rates in general and specific populations were reviewed and u...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 4, 2017 Category: Microbiology Source Type: research

Palliative care approaches to neonates with chronic respiratory failure
Neonates with chronic respiratory failure have uncertain prognosis and can face significant treatment burden. As the trajectory of the illness becomes more concerning, consultation with a pediatric palliative service should be considered, especially as therapeutic options shift from standard to “innovative.” Benefits include as follows: supporting emotionally conflicted providers and parents, maintaining transparency in determination of goals, and balancing medical progress with each individual patient’s and family’s best interests. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - February 4, 2017 Category: Perinatology & Neonatology Authors: Nicolas F.M. Porta Source Type: research

Extra-corporeal membrane oxygenation as an indispensable tool for a successful treatment of a pregnant woman with H1N1 infection in Brazil
Publication date: Available online 4 February 2017 Source:Respiratory Medicine Case Reports Author(s): Rodrigo T. Amancio, Celina Machado Acra, Vicente Cés de Souza Dantas (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 4, 2017 Category: Respiratory Medicine Source Type: research

EGFR targeted therapy in lung cancer; an evolving story
Publication date: Available online 4 February 2017 Source:Respiratory Medicine Case Reports Author(s): C. Bartholomew, L. Eastlake, P. Dunn, D. Yiannakis Specific oncogenes with driver mutations, such as the Epidermal Growth Factor Receptor (EGFR 1) gene can lead to non-small-cell lung cancer formation. Identification of these oncogenes, their driver mutations and downstream effects allow the targeting of these pathways by drugs. Such personalised therapy has become an important strategy in combating lung cancer and highlights the need to test for these mutations. Tyrosine Kinase Inhibitors (TKIs) against EGFR, such as Er...
Source: Respiratory Medicine Case Reports - February 4, 2017 Category: Respiratory Medicine Source Type: research

Lung cancer survival only increases by a small amount despite recent treatment advances
Publication date: Available online 4 February 2017 Source:The Lancet Respiratory Medicine Author(s): Sanjeet Bagcchi (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 4, 2017 Category: Respiratory Medicine Source Type: research

Landmark legal ruling sees Indian girl prescribed bedaquiline for XDR-TB
Publication date: Available online 4 February 2017 Source:The Lancet Respiratory Medicine Author(s): Tony Kirby (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 4, 2017 Category: Respiratory Medicine Source Type: research

Fluids and sepsis: changing the paradigm of fluid therapy: a case report
ConclusionsBecause fluid depletion in septic shock is caused by capillary leak and pathologic vasoplegia, continuation of fluid administration will drive intravascular fluid into the interstitial space, thereby producing marked tissue edema and disrupting vital oxygenation. Thus, fluids have the power to heal or kill. Therefore, management of patients with sepsis should entail early vasopressors with adequate fluid resuscitation followed by a conservative fluid regimen. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 4, 2017 Category: Journals (General) Source Type: research

Cutaneous tuberculosis over tattoo marks: An unusual occurrence
Publication date: Available online 3 February 2017 Source:Egyptian Journal of Chest Diseases and Tuberculosis Author(s): Savita Arya, Motilal Bunkar, Rajendra Takhar Among the paucibacillary form of tuberculosis cutaneous tuberculosis occurring very rarely. Lupus vulgaris is a variant of skin tuberculosis. Here we are reporting a case of 20year old boy presented with proliferative fungating lesion over tattoo mark. Tottooing was done by mobile tattoo artist in a fair. Diagnosis of skin tuberculosis was confirmed by histopathology suggestive of lupus vulgaris and treated with anti-tuberculous drugs. (Source: Egyptian Journ...
Source: Egyptian Journal of Chest Diseases and Tuberculosis - February 4, 2017 Category: Respiratory Medicine Source Type: research

Primary Care Issues in Rural Populations
Rural populations have different demographics and health issues compared to their metropolitan counterparts, including higher mortalities from ischemic heart disease, chronic obstructive pulmonary disease, unintentional injuries, motor vehicle accidents, and suicide. Rural primary care physicians (PCPs) have a unique position in counseling, preventing, and treating common issues that are specific to rural populations, such as motor vehicle accidents, unintentional injuries, pesticide poisoning, occupational respiratory illnesses, and mental illness. They are also in a unique position to address prevention and social determ...
Source: Primary Care: Clinics in Office Practice - February 3, 2017 Category: Primary Care Authors: Konstantinos E. Deligiannidis Source Type: research

Environmental Justice and Underserved Communities
Underserved communities suffer from environmental inequities. Gases lead to hypoxia and respiratory compromise, ozone to increased respiratory illnesses and decreased mental acuity, and mercury to prenatal cognitive disabilities and antisocial behaviors. Lead toxicity is associated with developmental delays. Cadmium is linked with cancer. The smaller sizes of air pollution particulate matter are pathogenic and are associated with cardiovascular and pulmonary disease and nervous system disorders. Bisphenol A is being studied for possible links to cancer and pregnancy risks. Physicians should be aware of these dangers, espec...
Source: Primary Care: Clinics in Office Practice - February 3, 2017 Category: Primary Care Authors: Vincent Morelli, Carol Ziegler, Omotayo Fawibe Source Type: research

Climate Change and Underserved Communities
Climate change is the greatest global health threat of the twenty-first century, yet it is not widely understood as a health hazard by primary care providers in the United States. Aside from increasing displacement of populations and acute trauma resulting from increasing frequency of natural disasters, the impact of climate change on temperature stress, vector-borne illnesses, cardiovascular and respiratory illnesses, and mental health is significant, with disproportionate impact on underserved and marginalized populations. Primary care providers must be aware of the impact of climate change on the health of their patient...
Source: Primary Care: Clinics in Office Practice - February 3, 2017 Category: Primary Care Authors: Carol Ziegler, Vincent Morelli, Omotayo Fawibe Source Type: research

Organizational Learning in a Cardiac Intensive Care Unit: A Learning History
Conclusion: The findings validate the relationship between psychological safety and organizational learning, offer insight into how CCUs become high-reliability organizations, and provide clinical leaders with guidance for achieving high reliability in their organizations. The findings also help validate the American Association of Critical-Care Nurses position that a healthy work environment is essential to achieving clinical excellence. Critical care unit teams should use these findings as a framework for collective reflection and planning to achieve their desired future. Further research is needed to validate the applic...
Source: Dimensions of Critical Care Nursing - February 3, 2017 Category: Nursing Tags: Leadership DIMENSION Source Type: research

Preparation of Specific Compartments of the Lungs for Pathologic and Biochemical Analysis of Toxicologic Responses.
Authors: Van Winkle LS, Kelty JS, Plopper CG Abstract This unit focuses on protocols for assessing microenvironment-specific responses in the thoracic lung tissues. Aspects of the entire respiratory system serve as potential targets for candidate toxicants, but each candidate toxicant may impact distinct sites due to differential distribution of either the toxicant or the target cells. Within the conducting airways, the composition of resident cell populations and the metabolic capabilities of the cell populations vary greatly. Thus, studies of this region of the lung require unique, site-selective methods to clear...
Source: Current Protocols in Toxicology - February 3, 2017 Category: Toxicology Tags: Curr Protoc Toxicol Source Type: research

Short-term Survival of Acute Respiratory Distress Syndrome Patients at a Single Tertiary Referral Centre in Indonesia.
CONCLUSION: the short-term survival rate of ARDS in developing countries  including Indonesia is still low and early management with optimal treatment provided within the first week may improve the survival rate. PMID: 28143991 [PubMed - in process] (Source: Acta medica Indonesiana)
Source: Acta medica Indonesiana - February 3, 2017 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Utility of Procalcitonin for Diagnosis of Superimposed Infections in Patients With Acute Heart Failure.
Authors: Mollar A, Miñana G, Villanueva MP, Guijarro J, Núñez J Abstract Respiratory infections are well-known precipitant factors for heart failure decompensations. Nevertheless, the diagnosis of life-threatening infections, such as pneumonia, is challenging. Pneumonia and acute heart failure often display overlapping clinical findings and, in other cases, more accurate infection-related findings are missing. In recent years, procalcitonin has emerged as a promising tool for early and accurate diagnosis of pneumonia and, interestingly, for guiding antibiotic therapy in patients with acute heart failure. We disc...
Source: Reviews in Cardiovascular Medicine - February 3, 2017 Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research

Usefulness of bronchoalveolar lavage and flow cytometry in patients with hematological malignancies and respiratory failure.
CONCLUSIONS: Our study confirms the clinical value of BAL for treatment decision making in patients with hematological malignancies and acute respiratory failure. PMID: 28143650 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 3, 2017 Category: Journals (General) Tags: Med Clin (Barc) Source Type: research

[Case Report] Maternal death from influenza in tropical Thailand
At 0033 h on Sept 9, 2015, a 17-year-old Thai woman, 33 weeks and 4 days into her first pregnancy and no medical history of note, presented to the emergency room of Phon Thong district hospital with a 1 day history of fever, cough, and sore throat. On presentation she was febrile (temperature 39 ·2°C) and tachycardic (pulse 129 beats per min) with a respiratory rate of 22 breaths per min and blood pressure 130/81 mm Hg. She was diagnosed with bronchitis, prescribed amoxicillin, paracetamol, and bromhexine, and discharged home. (Source: LANCET)
Source: LANCET - February 3, 2017 Category: Journals (General) Authors: Pipat Thongnoi, Prabda Praphasiri, Fatimah S Dawood, Kim A Lindblade Tags: Case Report Source Type: research

[Case Report Comment] Prevention is better than cure, but both require high quality evidence
In The Lancet,1 Pipat Thongnoi and colleagues report a case of severe respiratory failure secondary to influenza A infection in a young woman who was 33 weeks pregnant with triplets, which sadly resulted in the death of the mother and all three infants. The report highlights issues relevant to public health, obstetric care, emergency and critical care, and the generation of clinical evidence. (Source: LANCET)
Source: LANCET - February 3, 2017 Category: Journals (General) Authors: Steven A Webb, Edward Litton Tags: Case Report Comment Source Type: research

The effects of low tidal ventilation on lung strain correlate with respiratory system compliance
The effect of alterations in tidal volume on mortality of acute respiratory distress syndrome (ARDS) is determined by respiratory system compliance. We aimed to investigate the effects of different tidal volum... (Source: Critical Care)
Source: Critical Care - February 3, 2017 Category: Intensive Care Authors: Jianfeng Xie, Fang Jin, Chun Pan, Songqiao Liu, Ling Liu, Jingyuan Xu, Yi Yang and Haibo Qiu Source Type: research

Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries
Hyperoxia is common early in the course of resuscitation of critically ill patients. It has been associated with mortality in some, but not all, studies of cardiac arrest patients and other critically ill coho... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - February 3, 2017 Category: Respiratory Medicine Authors: Derek W. Russell, David R. Janz, William L. Emerson, Addison K. May, Gordon R. Bernard, Zhiguo Zhao, Tatsuki Koyama and Lorraine B. Ware Source Type: research

The role of serum procalcitonin in establishing the diagnosis and prognosis of pleural infection
Bacterial pleural infection requires prompt identification to enable appropriate investigation and treatment. In contrast to commonly used biomarkers such as C-reactive protein (CRP) and white cell count (WCC)... (Source: Respiratory Research)
Source: Respiratory Research - February 3, 2017 Category: Respiratory Medicine Authors: Giles Dixon, Adriana Lama-Lopez, Oliver J. Bintcliffe, Anna J. Morley, Clare E. Hooper and Nick A. Maskell Source Type: research

Clinical Features of Influenza and Acute Respiratory Illness in Older Adults at Least 50 Years of Age in an Outpatient Setting in the Republic of Korea: a Prospective, Observational, Cohort Study.
Authors: Kim WJ, Lee JS, Lee CK, Cheong HJ, Kim M, Monegal JS, Carneiro R, Kyaw MH, Haguinet F, Ray R, Matias G Abstract Two prospective, multi-centre, observational studies (GlaxoSmithKline [GSK] identifier No. 110938 and 112519) were performed over 2 influenza seasons (2007-2008 and 2008-2009) in the Republic of Korea (ROK) with the aim to evaluate the burden of laboratory-confirmed influenza (LCI) in patients ≥ 50 years of age seeking medical attention for acute respiratory illness (ARI). The median participant age was 58 years in the 2007-2008 season and 60 years in the 2008-2009 season. LCI was observed in 1...
Source: Journal of Korean Medical Science - February 3, 2017 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Who Dies after ICU Discharge? Retrospective Analysis of Prognostic Factors for In-Hospital Mortality of ICU Survivors.
In conclusion, a significant proportion of in-hospital mortality is predictable and those who die in hospital after ICU discharge tend to be severely-ill, with comorbidities of hematologic disease and solid tumor, and anemic and thrombocytopenic upon ICU discharge. PMID: 28145659 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - February 3, 2017 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Post-polio syndrome. Cases report and review of literature.
In this study we described three cases of people who developed PPS years after Haine-Medine disease and correlation between their EMG results and clinical status. We also analyzed electromyography results both after one month since first PPS signs occurred as well as after few years. Presentation of dynamic changes in EMG was the most important aim of that study. PMID: 28209439 [PubMed - as supplied by publisher] (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - February 3, 2017 Category: Neurology Authors: Pastuszak Ż, Stępień A, Tomczykiewicz K, Piusińska-Macoch R, Galbarczyk D, Rolewska A Tags: Neurol Neurochir Pol Source Type: research

Oleiagrimonas citrea sp. nov., a marine bacterium isolated from tidal flat sediment and emended description of the genus Oleiagrimonas Fang et al. 2015 and Oleiagrimonas soli.
Abstract A Gram-negative, aerobic, rod-shaped (1.8-2.3 μm  0.4-0.6 μm), and motile marine bacterium, designated as MEBiC09124T was isolated from tidal flat sediment of the Suncheon Bay, South Korea. The 16S rRNA gene sequence analysis revealed that strain MEBiC09124T showed high similarity with the Oleiagrimonas soli 3.5XT (96.7%). Growth was observed at 18-38 OC (optimum 30 OC), at pH 4.0-8.5 (optimum pH 7.5) and with 0-6 % (optimum 2.5%) NaCl. The predominant cellular fatty acids were iso-C15 : 0 (22.6%), iso-C16 : 0 (16.0%), iso-C17 : 0 (10.0%) and summed feature 9 (comprised of 10-methyl-C16 : 0 and/or is...
Source: International Journal of Systematic and Evolutionary Microbiology - February 3, 2017 Category: Microbiology Authors: Yang SH, Seo HS, Seong CN, Kwon KK Tags: Int J Syst Evol Microbiol Source Type: research

Extracorporeal Membrane Oxygenation for  Acute Respiratory Distress Syndrome After Pneumonectomy.
CONCLUSIONS: Hospital survival was better than predicted before ECMO insertion. In severe and refractory ppARDS, VV-ECMO allows lung recovery and therefore increased survival. PMID: 28168966 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - February 3, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Reeb J, Olland A, Pottecher J, Delabranche X, Schaeffer M, Renaud S, Santelmo N, Kessler R, Massard G, Falcoz PE Tags: Ann Thorac Surg Source Type: research

A live-attenuated influenza vaccine for H3N2 canine influenza virus.
Abstract Canine influenza is a contagious respiratory disease in dogs caused by two subtypes (H3N2 and H3N8) of canine influenza virus (CIV). Currently, only inactivated influenza vaccines (IIVs) are available for the prevention of CIVs. Historically, live-attenuated influenza vaccines (LAIVs) have been shown to produce better immunogenicity and protection efficacy than IIVs. Here, we have engineered a CIV H3N2 LAIV by using the internal genes of a previously described CIV H3N8 LAIV as a master donor virus (MDV) and the surface HA and NA genes of a circulating CIV H3N2 strain. Our findings show that CIV H3N2 LAIV ...
Source: Virology - February 3, 2017 Category: Virology Authors: Rodriguez L, Nogales A, Reilly EC, Topham DJ, Murcia PR, Parrish CR, Martinez Sobrido L Tags: Virology Source Type: research

Cancer metabolism in space and time: beyond the Warburg effect.
This article is part of a Special Issue entitled Respiratory complex I, edited by Giuseppe Gasparre, Rodrigue Rossignol and Pierre Sonveaux. PMID: 28167100 [PubMed - as supplied by publisher] (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - February 3, 2017 Category: Biochemistry Authors: Danhier P, Bański P, Payen VL, Grasso D, Ippolito L, Sonveaux P, Porporato PE Tags: Biochim Biophys Acta Source Type: research

Health burden attributable to ambient PM2.5 in China.
Abstract In China, over 1.3 billion people have high health risks associated with exposure to ambient fine particulate matter (PM2.5) that exceeds the World Health Organization (WHO) Air Quality Guidelines (AQG). The PM2.5 mass concentrations from 1382 national air quality monitoring stations in 367 cities, between January 2014 and December 2016, were analyzed to estimate the health burden attributable to ambient PM2.5 across China. The integrated exposure-response model was applied to estimate the relative risks of disease-specific mortality. Disease-specific mortality baselines in province-level administrative u...
Source: Environmental Pollution - February 3, 2017 Category: Environmental Health Authors: Song C, He J, Wu L, Jin T, Chen X, Li R, Ren P, Zhang L, Mao H Tags: Environ Pollut Source Type: research

Diagnosis of Actinomyces graevenitzii Lung Infection using Linear EBUS.
PMID: 28169034 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - February 3, 2017 Category: Respiratory Medicine Authors: Caballero Vázquez A, Cruz Rueda JJ, Ceballos Gutierrez JA Tags: Arch Bronconeumol Source Type: research

Indoor environmental factors associated with pulmonary function among adults in an acid rain-plagued city in Southwest China.
CONCLUSIONS: This study demonstrated impaired pulmonary function among adults who were exposed to indoor risk factors, such as coal fires and cigarette smoking compared to non-users in the winter season and emphasizes the need for public health efforts to decrease exposure to indoor air pollution. PMID: 28160097 [PubMed - as supplied by publisher] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - February 3, 2017 Category: Journals (General) Authors: Yu J, Zhang L, Luo Y, Tang Y, Tuo F, Yang J, Xu J Tags: Wien Klin Wochenschr Source Type: research

Pediatric Cardiopulmonary Arrest in the Postanesthesia Care Unit, Rare but Preventable: Analysis of Data From Wake Up Safe, The Pediatric Anesthesia Quality Improvement Initiative.
CONCLUSIONS: PACU CA events are rare and generally survivable, with better outcomes for respiratory-based events, but most were deemed preventable, suggesting a need for further vigilance in the early postoperative period. Maintenance of monitoring during patient transport to PACU and continuing care by anesthesia care providers until emergence from anesthesia may further reduce the preventable arrest rate. The root cause analyses conducted by individual institutions reporting these data to the Wake Up Safe provided only limited insight, so multicenter collaborative approaches may allow for greater insight into effective C...
Source: Anesthesia and Analgesia - February 3, 2017 Category: Anesthesiology Authors: Christensen RE, Haydar B, Voepel-Lewis TD Tags: Anesth Analg Source Type: research

Estimating sleep time from non-EEG-based PSG signals in the diagnosis of sleep-disordered breathing.
CONCLUSIONS: In the sleep laboratory, subjects are immobile for longer periods when awake and for shorter periods when asleep. The experimental TST was similar to EEG-defined TST and could be used to diagnose SDB with a much higher sensitivity than the type 3 method. PMID: 28155104 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - February 3, 2017 Category: Sleep Medicine Authors: Norman MB, Sullivan CE Tags: Sleep Breath Source Type: research

Respiratory disorders and the prevalence of sleep bruxism among schoolchildren aged 8 to 11  years.
CONCLUSION: Rhinitis and sinusitis were associated with sleep bruxism. Moreover, sleep bruxism was more prevalent among children whose mothers had a higher level of schooling and those with higher degrees of stress. PMID: 28155103 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - February 3, 2017 Category: Sleep Medicine Authors: Drumond CL, Souza DS, Serra-Negra JM, Marques LS, Ramos-Jorge ML, Ramos-Jorge J Tags: Sleep Breath Source Type: research

Changes to radiotherapy utilisation in Western NSW after the opening of a local service.
CONCLUSIONS: A new radiotherapy service in a sparsely populated health district significantly changed the pattern of radiotherapy use for those who lived only in the Orange region. Treatment capacity at the Orange radiotherapy centre has doubled with the opening of a second linear accelerator since this study was conducted. Thus, a follow-up study is recommended to ascertain if radiotherapy rates remain low in the regions beyond Orange. PMID: 28160454 [PubMed - as supplied by publisher] (Source: Rural Remote Health)
Source: Rural Remote Health - February 3, 2017 Category: Rural Health Authors: Butler SM Tags: J Med Radiat Sci Source Type: research

Clinical Features and Prognostic Factors in Presumed Ocular Tuberculosis.
CONCLUSIONS: The diagnosis of ocular TB can be difficult due to the lack of extraocular manifestations and the broad spectrum of ocular features. A longer duration of symptoms at diagnosis was associated with poorer visual outcomes and cataracts. Therefore, efforts should be made to avoid a delay in the diagnosis of ocular TB and to identify prognostic factors for visual outcomes and complications. PMID: 28157425 [PubMed - as supplied by publisher] (Source: Current Eye Research)
Source: Current Eye Research - February 3, 2017 Category: Opthalmology Authors: Urzua CA, Lantigua Y, Abuauad S, Liberman P, Berger O, Sabat P, Velasquez V, Castiglione E, Calonge M Tags: Curr Eye Res Source Type: research

Fifty Years of Research in ARDS. The Epidemiology of ARDS: A Fiftieth Birthday Review.
Abstract Since its first description 50 years ago, no other ICU syndrome has been as extensively studied as ARDS. Nevertheless intensivists' favorite darling has not revealed all its secrets yet and many epidemiological questions remain unsolved. The lack of gold standard tests jeopardizes accurate diagnosis, leading to uncertainties in the actual incidence of this syndrome across different areas with reported ranges as wide as 3.65 to 81 cases per 100,000 persons-year. Likewise evaluation of its evolution over time is difficult due to changes in ARDS definition and under-recognition by clinicians. Despite these l...
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2017 Category: Respiratory Medicine Authors: Pham T, Rubenfeld GD Tags: Am J Respir Crit Care Med Source Type: research

Microbes Associate with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis.
CONCLUSIONS: These findings suggest that host-microbiome interactions influence PFS and fibroblast responsiveness. PMID: 28157391 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2017 Category: Respiratory Medicine Authors: Huang Y, Ma SF, Espindola MS, Vij R, Oldham JM, Huffnagle GB, Erb-Downward JR, Flaherty KR, Moore BB, White ES, Zhou T, Li J, Lussier YA, Han MK, Kaminski N, Garcia JG, Hogaboam CM, Martinez FJ, Noth I, COMET Investigators Tags: Am J Respir Crit Care Med Source Type: research

Activated β2 Integrins Restrict Neutrophil Recruitment During Murine Acute Pseudomonal Pneumonia.
Abstract Rapid neutrophil recruitment is critical for the efficient clearance of bacterial pathogens from the lungs. While β2 integrins and their activation are required for neutrophil recruitment from postcapillary venules of the systemic circulation into inflamed tissues, the involvement of integrins in neutrophil recruitment in response to respiratory infection varies between bacterial pathogens. For stimuli eliciting β2 integrin-dependent neutrophil influx, including Pseudomonas aeruginosa, it remains unclear whether the activation of β2 integrins is an essential step in this process. In the current study, ...
Source: Am J Respir Cell Mol... - February 3, 2017 Category: Respiratory Medicine Authors: Wilson ZS, Ahn LB, Serratelli WS, Belley MD, Lomas-Neira J, Sen M, Lefort CT Tags: Am J Respir Cell Mol Biol Source Type: research

The Role of NOD-like Receptors in Pulmonary Infection.
Abstract Pneumonia is caused by both viral and bacterial pathogens and is responsible for a significant health burden in the Unites States. The innate immune system is the human body's first line of defense against these pathogens. The recognition of invading pathogens via pattern recognition receptors (PRRs) leads to proinflammatory cytokine and chemokine production followed by recruitment and activation of effector immune cells. The nonspecific inflammatory nature of the innate immune response can result in immunopathology that is detrimental to the host. In this review, we focus on one class of PRRs, the nucleo...
Source: Am J Respir Cell Mol... - February 3, 2017 Category: Respiratory Medicine Authors: Wiese KM, Coates BM, Ridge KM Tags: Am J Respir Cell Mol Biol Source Type: research

Impact of data-driven cardiac respiratory motion correction on the extent and severity of myocardial perfusion defects with free-breathing CZT SPECT
ConclusionsA substantial number of MPI studies presented significant cardiac RM. Cardiac RM compensation showed a frequent impact on the extent/severity of MPD. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 3, 2017 Category: Nuclear Medicine Source Type: research

Detection of a novel sapelovirus in central nervous tissue of pigs with polioencephalomyelitis in the USA
Summary An approximately 3,000 finishing swine operation in the United States experienced an outbreak of an atypical neurologic disease in 11‐weeks‐old pigs with an overall morbidity of 20% and case fatality rate of 30%. The clinical onset and progression of signs in affected pigs varied but included inappetence, compromised ambulation, ataxia, incoordination, mental dullness, paresis, paralysis and decreased response to environmental stimuli. Tissues from affected pigs were submitted for diagnostic investigation. Histopathologic examination of the cerebrum, cerebellum and spinal cord revealed severe lymphoplasmacytic ...
Source: Transboundary and Emerging Diseases - February 3, 2017 Category: Veterinary Research Authors: P. H. E. Arruda, B. L. Arruda, K. J. Schwartz, F. Vannucci, T. Resende, A. Rovira, P. Sundberg, J. Nietfeld, B. M. Hause Tags: Rapid Communication Source Type: research

A Trans-Nasal Aerosol Delivery Device for Efficient Pulmonary Deposition
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - February 3, 2017 Category: Respiratory Medicine Authors: Kirby L. Zeman Juan Rojas Balcazar Fred Fuller Karl H. Donn Richard C. Boucher William D. Bennett Scott H. Donaldson Source Type: research

Renal function in patients with obstructive sleep apnea
(Source: Sleep and Breathing)
Source: Sleep and Breathing - February 3, 2017 Category: Respiratory Medicine Source Type: research