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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Evaluation of treatment failure outcome and its predictors among pulmonary tuberculosis patients in Sharkia Governorate, 2013 –2014
Conclusion This study showed that the treatment failure rate in our locality is relatively high. Positive sputum smear at 2months of TB treatment, radiological findings and retreatment patients were found to be predictors of TB treatment failure that should be recognized early and closely followed up. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - September 29, 2016 Category: Respiratory Medicine Source Type: research

Asia's air: population health after rapid industrialisation
Publication date: Available online 28 September 2016 Source:The Lancet Respiratory Medicine Author(s): Jules Morgan (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - September 29, 2016 Category: Respiratory Medicine Source Type: research

Effect of heavy-intensity ‘priming' exercise on oxygen uptake and muscle deoxygenation kinetics during moderate-intensity step-transitions initiated from an elevated work rate
We examined the effect of heavy-intensity ‘priming’ exercise on the rate of adjustment of pulmonary O2 uptake (τV̇O2p) initiated from elevated intensities. Fourteen men (separated into two groups: τV̇O2p ≤25s [Fast] or τV̇O2p >25s [Slow]) completed step-transitions from 20W-to-45%lactate threshold (LT; lower-step, LS) and 45%-to-90%LT (upper-step, US) performed (i) without; and (ii) with US preceded by heavy-intensity exercise (HUS). Breath-by-breath V̇O2p and near-infrared spectroscopy-derived muscle deoxygenation ([HHb+Mb]) were measured. Compared to LS, τV̇O2p was greater (p<0.05) in US in b...
Source: Respiratory Physiology and Neurobiology - September 29, 2016 Category: Respiratory Medicine Source Type: research

Should the diagnosis of COPD be based on a single spirometry test?
npj Primary Care Respiratory Medicine, Published online: 29 September 2016; doi:10.1038/npjpcrm.2016.59 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - September 29, 2016 Category: Primary Care Authors: Tjard R Schermer Bas Robberts Alan J Crockett Bart P Thoonen Annelies Lucas Joke Grootens Ivo J Smeele Cindy Thamrin Helen K Reddel Source Type: research

Emergency nurses ’ decisions regarding frequency and nature of vital sign assessment
ConclusionEmergency nurses are tailoring vital sign assessment to patients’ clinical status and nurses are integrating known vital sign data into vital sign decision making.This article is protected by copyright. All rights reserved. (Source: Journal of Clinical Nursing)
Source: Journal of Clinical Nursing - September 29, 2016 Category: Nursing Authors: Katherine Lambe, Judy Currey, Julie Considine Tags: Original Article Source Type: research

Implementation of respiratory protection measures: Visitors of residential care homes for the elderly
Publication date: Available online 28 September 2016 Source:American Journal of Infection Control Author(s): Diana T.F. Lee, Doris S.F. Yu, Margaret Ip, Jennifer Y.M. Tang To evaluate the implementation of respiratory protection measures for and by visitors of residential care homes for the elderly in Hong Kong, a territory-wide cross-sectional survey was conducted. A total of 87 infection control officers, 1,763 health care workers, and 520 visitors from 87 homes completed the questionnaires. Rules on respiratory protection for visitors were found to vary across residential care homes for the elderly. Uncooperative visit...
Source: American Journal of Infection Control - September 29, 2016 Category: Infectious Diseases Source Type: research

A 14-year-old boy with extranodal natural killer cell lymphoma of the nose, nasopharynx, larynx, and trachea in remission 6years after primary diagnosis. A longitudinal case report
Publication date: Available online 12 August 2016 Source:American Journal of Otolaryngology Author(s): Anil Gungor, Lindsey Pennington, Senthil Sankararaman, Samer Zaid-Kaylani, Majed Aldin Jeroudi Nasal type extranodal natural killer/T-cell lymphoma (ENKTL) is a rare lymphoma in the USA and Europe but endemic in East Asia and in areas of South and Central America. Clinically natural killer cell lymphomas are divided into three categories; nasal, non-nasal and aggressive lymphoma/leukemia subtypes. ENKTL, nasal type occurs in the nose and can extend to the upper aero-digestive tract as reported in this longitudinal case s...
Source: American Journal of Otolaryngology - September 29, 2016 Category: Endocrinology Source Type: research

Analgesia: Screening for cleaner pain relief
Nature Reviews Drug Discovery 15, 677 (2016). doi:10.1038/nrd.2016.204 Author: Katie Kingwell Activation of the μ-opioid receptor by morphine and related opioids provides valuable analgesia but can also lead to addiction and potentially lethal side effects such as respiratory depression. Now, an article in Nature reports a structure-based approach to the discovery of novel 'biased' ligands (Source: Nature Reviews Drug Discovery)
Source: Nature Reviews Drug Discovery - September 29, 2016 Category: Drugs & Pharmacology Authors: Katie Kingwell Tags: Research Highlight Source Type: research

Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco
This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - September 28, 2016 Category: Virology Authors: A Annamalay, I. Jroundi, J Bizzintino, S ‐K Khoo, Guicheng Zhang, Deborah Lehmann, Ingrid Laing, James Gern, Jack Goldblatt, C. Mahraoui, R. Benmessaoud, C. Moraleda, Q. Bassat, P Le Souëf Tags: Research Article Source Type: research

A rare cause of cavitatory pneumonia.
Abstract Radiographic findings of thick walled cavities in the lungs are typically seen in mycobacterial infections, malignant lesions, fungal infections, pulmonary vasculitis or other inflammatory lesions of the lungs. Necrotizing infections of the lungs caused by gram negative bacteria (Klebsiella, Psudomonas, Legionella) and Staphylococcus aureus may also form cavities of varying thickness, with consolidation. Escherichia coli pneumonia causing pulmonary cavities is very rare and the few cases reported are of pneumatocele formation. Here we present an unusual case of Escherichia coli infection as a rare cause o...
Source: Respiratory Care - September 28, 2016 Category: Respiratory Medicine Authors: Harsha NS, Sandeepa HS, Hemantha Kumar S, Prakash B, Jayalakshmi K Tags: Respir Med Case Rep Source Type: research

The role of the TGF-SMAD signalling pathway in the etiopathogenesis of severe asthma.
Abstract Asthma is a chronic inflammatory heterogeneous disease of the lower respiratory tract characterised by the occurrence of bronchial hyper-responsiveness and paroxysmal, changeable bronchial obstruction. Transforming growth factor-beta (TGF-b) is one of the cytokines involved in mediating airway inflammation and remodelling. The level of TGF-b1 gene expression correlates with severity of symptoms. Alterations in the main SMAD signal transmission, overexpression of TGF-b genes and changes in the transcriptome cause excessive secretion of TGF-b and its increased expression in target cells, which clinically in...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Koćwin M, Jonakowski M, Przemęcka M, Zioło J, Panek M, Kuna P Tags: Pneumonol Alergol Pol Source Type: research

Persons with allergy symptoms use alternative medicine more often.
CONCLUSIONS: The occurrence of allergic diseases and asthma influences the frequency of alternative medicine use. However the frequency of alternative medicine use does not depend on allergic disease or asthma being confirmed by a doctor. PMID: 27672066 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kłak A, Raciborski F, Krzych-Fałta E, Opoczyńska-Świeżewska D, Szymański J, Lipiec A, Piekarska B, Sybilski A, Tomaszewska A, Samoliński B Tags: Pneumonol Alergol Pol Source Type: research

Implementing Capnography in the PACU  and Beyond.
This article describes the implementation of monitoring program for high risk patients. Early recognition of respiratory depression via capnography has enabled Sauk Prairie Memorial Hospital to safely care for patients having intravenous and intrathecal narcotics. PMID: 27667345 [PubMed - in process] (Source: Journal of Perianesthesia Nursing)
Source: Journal of Perianesthesia Nursing - September 28, 2016 Category: Nursing Authors: Oswald L, Zeuske T, Pfeffer J Tags: J Perianesth Nurs Source Type: research

The Impact of Case Finding on the Recruitment Yield for COPD Research in Primary Care: An Observational Study
Background: Recruiting patients for research in primary care is difficult with diseases that tend to remain underdiagnosed, such as chronic obstructive pulmonary disease (COPD). Researchers may consider introducing case finding into patient recruitment, but the impact on recruitment yield is largely unknown.Objectives: To assess the impact of case finding on recruitment yield and population characteristics in primary care-based COPD research.Methods: For a cluster randomized controlled trial of COPD in primary care, an opportunistic case finding strategy was introduced into patient recruitment, in addition to recruiting pa...
Source: Respiration - September 28, 2016 Category: Respiratory Medicine Source Type: research

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations
Previously, we observed increased serum levels of damage‐associated molecular patterns (DAMPs) during COPD exacerbations. Here, gene expression of DAMP receptors was measured in peripheral blood neutrophils of COPD patients during stable disease and severe acute exacerbation. The expression of toll‐like receptor (TLR)2, TLR4 and NLR family, pyrin domain‐containing 3 (NLRP3) was significantly increased, while serum levels of the soluble form of the decoy receptor for advanced glycation end‐product (sRAGE) were decreased during exacerbation. Together, these data indicate that increased DAMP signalling contributes to ...
Source: Respirology - September 28, 2016 Category: Respiratory Medicine Authors: Simon D. Pouwels, Wouter H. van Geffen, Marnix R. Jonker, Huib A. M. Kerstjens, Martijn C. Nawijn, Irene H. Heijink Tags: Scientific Letter Source Type: research

Postepy Hig Med Dosw 2016; 70:1017-1025 "Short-term exposure to ambient fine particulate matter (PM2,5 and PM10) and the risk of heart rhythm abnormalities and stroke"
Results of epidemiological studies suggest a significant impact of ambient particulate matter air pollution (PM10 and PM2,5) on the health of the population. Increased level of these pollutants is connected with increased rate of daily mortality and hospitalizations due to cardiovascular diseases. Among analyzed health effects, heart arrhythmias and stroke are mentioned most frequently. The aim of the study was to present the current knowledge of potential influence of the exposure to fine particulate matter on the presence of arrhythmias and strokes. Subject literature review suggests, that there is a link between short-t...
Source: Postepy higieny i medycyny doswiadczalnej - September 28, 2016 Category: Research Tags: Review article Source Type: research

Postepy Hig Med Dosw 2016; 70:1026-1031 "Role of oncogene 24p3 neutrophil gelatinase-associated lipocalin (NGAL) in digestive system cancers"
Neutrophil gelatinase-associated lipocalin, known also as 24p3 lipocalin, lipocalin-2 or uterocalin (in mouse), is a small secretory protein binding small molecular weight ligands which takes part in numerous processes including apoptosis induction in leukocytes, iron transport, smell, and prostaglandins and retinol transport [19]. It was discovered in activated neutrophils as a covalent peptide associated with human gelatinase neutrophils [7]. Neutrophil lipocalin is secreted physiologically in the digestive system, respiratory tract, renal tubular cells, liver or immunity system. Systematic (circulated in plasma) neutrop...
Source: Postepy higieny i medycyny doswiadczalnej - September 28, 2016 Category: Research Tags: Review article Source Type: research

Effect of fermented milk with Lactobacillus paracasei CBA L74 on gastrointestinal and respiratory infections in children: Multicenter randomized controlled trial
Preliminary evidence suggest that cow's milk (CM) or rice fermented with Lactobacillus paracasei CBA L74 prevent common infectious diseases (CIDs) in children attending daycare. We aim to confirm the efficacy of CM fermented with L. paracasei CBA L74 against CIDs. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - September 28, 2016 Category: Gastroenterology Authors: R. Berni Canani, G. Corsello, R. Nocerino, M. Carta, R. Marinello, M. Picca, G. De Marco, M. Micillo, D. Ferrara, P. Vigneri, G. Cecere, P. Ferri, P. Roggero, G. Bedogni, F. Mosca Tags: P104 Source Type: research

A Cross-sectional Assessment of Risk Factors of Non-Communicable Diseases in a Sub-Himalayan Region of West Bengal, India Using who Steps Approach.
CONCLUSIONS: A high prevalence of risk factors for non-communicable diseases was found in Siliguri city which emphasizes the need of interventions to reduce these risk factors. PMID: 27666902 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - September 28, 2016 Category: Journals (General) Tags: J Assoc Physicians India Source Type: research

Evaluation of monitoring strategies for childhood asthma.
Authors: Brouwer ML, Wijngaart LS, Hugen CA, Gerrits GP, Roukema J, Merkus PJ Abstract INTRODUCTION: The goal of monitoring pediatric asthma is to obtain and maintain asthma control, which is defined as minimizing asthma symptoms, restrictions to daily activities and the use of rescue medication. Long term goals include reducing the risk of fixed airflow limitation, and preventing asthma exacerbations and side effects of treatment. Several monitoring tools are available but no consensus exists on how to monitor patients in the most optimal way. AREAS COVERED: In this review, we provide an overview of different ...
Source: Expert Review of Respiratory Medicine - September 28, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Stability of FeNO and airway hyperresponsiveness to mannitol in untreated asthmatics.
CONCLUSIONS: In steroid-free non-smoking asthmatics with constant symptom scores and lung function, airway responsiveness to mannitol remained at the same level over a period of months, while a minor change in exhaled FeNO was reported. These results suggest that mannitol is a stable, reliable marker of clinical disease activity. PMID: 27668981 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - September 28, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Bacteraemic urinary tract infections may mimic respiratory infections: a nested case –control study
AbstractDaily practice suggests that respiratory signs may be observed in bacteraemic urinary infections (BUI). Our objective was to search for an association between the presence of respiratory symptoms and the bacteraemic nature of urinary tract infections (UTI). A nested case –control study was carried out based on our computerised dashboard from January 2011 to June 2015. Cases were defined as patients with a BUI due to Enterobacteriaceae species, identified in blood and urine cultures. Controls had fever and a positive urinary sample but sterile blood cultures (NBUI) and a final diagnosis of urinary infection. Patie...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 28, 2016 Category: Microbiology Source Type: research

Tigecycline use in the outpatient parenteral antibiotic therapy setting
AbstractIn the context of globally increasing antimicrobial resistance, tigecycline appears to be a useful therapeutic option. The need for prolonged courses for complex infections has prompted consideration of its use via outpatient parenteral antibiotic therapy (OPAT) programmes, although clinical outcomes when used in this setting remain unknown. We retrospectively reviewed the patient characteristics and outcomes of 11 patients who received tigecycline, most commonly delivered as 100  mg once daily, via OPAT at three tertiary Australian hospitals. Rates of co-morbidity and prior antibiotic use were high. Patients had ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 28, 2016 Category: Microbiology Source Type: research

The use of multiplex PCR for the diagnosis of viral severe acute respiratory infection in children: a high rate of co-detection during the winter season
This study confirms the high rate of detection of viral nucleic acids by multiplex PCR among hospitalized children admitted with SARI, as well as the high rate of co-de tection of multiple viruses. AdV, HBoV, HRV, HEV, and HCoV-OC43 were also detected in asymptomatic children, resulting in challenges in clinical interpretation. Studies are required to provide quantitative conclusions that will facilitate clinical interpretation and application of the results in the clinical setting. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 28, 2016 Category: Microbiology Source Type: research

Burden of allergic respiratory disease: a systematic review
This meta-analysis compared the health-related quality of life (HRQL) of patients with allergic rhinitis (AR) and/or allergic asthma (AA) caused by perennial house dust mite (HDM) versus AR and/or AA caused by... (Source: Clinical and Molecular Allergy)
Source: Clinical and Molecular Allergy - September 28, 2016 Category: Allergy & Immunology Authors: A. Linneberg, K. Dam Petersen, J. Hahn-Pedersen, E. Hammerby, N. Serup-Hansen and N. Boxall Source Type: research

Can diaphragmatic ultrasonography performed during the T-tube trial predict weaning failure? The role of diaphragmatic rapid shallow breathing index
The rapid shallow breathing index (RSBI), which is the ratio between respiratory rate (RR) and tidal volume (VT), is one of the most widely used indices to predict weaning outcome. Whereas the diaphragm plays ... (Source: Critical Care)
Source: Critical Care - September 28, 2016 Category: Intensive Care Authors: Savino Spadaro, Salvatore Grasso, Tommaso Mauri, Francesca Dalla Corte, Valentina Alvisi, Riccardo Ragazzi, Valentina Cricca, Giulia Biondi, Rossella Di Mussi, Elisabetta Marangoni and Carlo Alberto Volta Source Type: research

Paper-based in-vitro model for on-chip investigation of the human respiratory system
We present the use of direct-patterned laser-treated hydrophobic paper as an effective semi-permeable membrane,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - September 28, 2016 Category: Chemistry Authors: Rahim Rahimi Source Type: research

Insights into the pathogenesis of Mycoplasma pneumoniae (Review).
Authors: He J, Liu M, Ye Z, Tan T, Liu X, You X, Zeng Y, Wu Y Abstract Mycoplasma are the smallest prokaryotic microbes present in nature. These wall‑less, malleable organisms can pass through cell filters, and grow and propagate under cell‑free conditions in vitro. Of the pathogenic Mycoplasma Mycoplasma pneumoniae has been examined the most. In addition to primary atypical pneumonia and community‑acquired pneumonia with predominantly respiratory symptoms, M. pneumoniae can also induce autoimmune hemolytic anemia and other diseases in the blood, cardiovascular system, gastrointestinal tract and skin, and ...
Source: Molecular Medicine Reports - September 28, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

A novel NDUFS4 frameshift mutation causes Leigh disease in the Hutterite population
Leigh disease is a progressive, infantile‐onset, neurodegenerative disorder characterized by feeding difficulties, failure to thrive, hypotonia, seizures, and central respiratory compromise. Metabolic and neuroimaging investigations typically identify abnormalities consistent with a disorder of mitochondrial energy metabolism. Mutations in more than 35 genes affecting the mitochondrial respiratory chain encoded from both the nuclear and mitochondrial genomes have been associated with Leigh disease. The clinical presentations of five individuals of Hutterite descent with Leigh disease are described herein. An identity‐b...
Source: American Journal of Medical Genetics Part A - September 28, 2016 Category: Genetics & Stem Cells Authors: Ryan E. Lamont, Chandree L. Beaulieu, Francois P. Bernier, Rebecca Sparkes, A. Micheil Innes, Candice Jackel ‐Cram, Carole Ober, Jillian S. Parboosingh, Edmond G. Lemire Tags: Original Article Source Type: research

Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study [Proteomics and Protein Markers]
CONCLUSIONS: SN concentrations measured on ICU admission provided incremental prognostic information to established risk indices in patients with CV-related ARF, but not in patients with non–CV-related ARF. (Source: Clinical Chemistry)
Source: Clinical Chemistry - September 28, 2016 Category: Chemistry Authors: Myhre, P. L., Ottesen, A. H., Okkonen, M., Linko, R., Stridsberg, M., Nygard, S., Christensen, G., Pettila, V., Omland, T., Rosjo, H., on behalf of the FINNALI Laboratory Study Group Tags: Proteomics and Protein Markers Source Type: research

The National Early Warning Score (NEWS) for outcome prediction in emergency department patients with community-acquired pneumonia: results from a 6-year prospective cohort study
Conclusions NEWS provides additional prognostic information with regard to risk of ICU admission and complications and thereby improves traditional clinical-risk scores in the management of patients with CAP in the ED setting. Trial registration number ISRCTN95122877; Post-results. (Source: BMJ Open)
Source: BMJ Open - September 28, 2016 Category: Journals (General) Authors: Sbiti-Rohr, D., Kutz, A., Christ-Crain, M., Thomann, R., Zimmerli, W., Hoess, C., Henzen, C., Mueller, B., Schuetz, P., for the ProHOSP Study Group, Schild, Regez, Bossart, Blum, Wolbers, Neidert, Suter, Bucher, Mueller, Chaudry, Haeuptle, Zarbosky, Fiume Tags: Open access, Emergency medicine, Respiratory medicine Research Source Type: research

Use of palivizumab with other infection control measures to control respiratory syncytial virus outbreaks in neonatal care units
Conclusion: During nosocomial outbreaks of RSV, administration of palivizumab to all infants in NICU appears to be rational and may help contain outbreaks. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - September 28, 2016 Category: Tropical Medicine Authors: Hammoud, M. S., Al-Taiar, A., Raina, A., Elsori, D., Al-Qabandi, S., Al-Essa, M. Tags: Original Papers Source Type: research

Effect of Treatment of Premature Infants with Respiratory Distress Using Low-cost Bubble CPAP in a Rural African Hospital
Conclusion: BCPAP has contributed significantly to favorable outcomes for preterm infants with RDS at AIC Kijabe Hospital. The use of this simple technology should be considered and studied for expansion to all hospitals in Kenya that care for preterm infants. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - September 28, 2016 Category: Tropical Medicine Authors: Myhre, J., Immaculate, M., Okeyo, B., Anand, M., Omoding, A., Myhre, L., Okeyo, L., Barasa, I., Letchford, S. Tags: Original Papers Source Type: research

Paramyxovirus Infection: Mortality and Morbidity in a Pediatric Intensive Care Unit
Conclusions: Infections with paramyxoviruses account for 5% of PICU admissions and significant morbidity. Patient with premorbid history of malignancy and co-morbidity of bacteremia are associated with non-survival. March and July appeared to be the two peak months for PICU admissions with paramyxoviruses. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - September 28, 2016 Category: Tropical Medicine Authors: Tong, A. S. W., Hon, K. L., Tsang, Y. C. K., Chan, R. W. Y., Chan, C. C., Leung, T. F., Chan, P. K. S. Tags: Original Papers Source Type: research

Health implications of atmospheric aerosols from asbestos-bearing road pavements traditionally used in Southern Brazil.
Abstract Serpentine and amphibole asbestos occur naturally in certain geologic settings worldwide, most commonly in association with ultramafic rocks, along associated faults. Ultramafic rocks have been used in Piên County, Southern Brazil for decades for the purpose of road paving in rural and urban areas, but without the awareness of their adverse environmental and health impact. The aim of this study was the chemical characterization of aerosols re-suspended in two rural roads of Piên, paved with ultramafic rocks and to estimate the pulmonary deposition of asbestos aerosols. Bulk aerosol samples were analyzed...
Source: Environmental Science and Pollution Research International - September 28, 2016 Category: Environmental Health Authors: Godoi RH, Gonçalves SJ, Sayama C, Polezer G, Reis Neto JM, Alföldy B, Van Grieken R, Riedi CA, Yamamoto CI, Godoi AF, Bencs L Tags: Environ Sci Pollut Res Int Source Type: research

Compassionate care improved my physical and mental health.
Abstract I met Fiona Barrett-Gray, lead nurse in respiratory illnesses at the North Carlisle Medical Practice, more than 12 years ago and her professional and compassionate care has changed my life. I know of many other patients with respiratory illnesses who she has helped cope with loneliness and panic attacks. PMID: 27682570 [PubMed - in process] (Source: Nursing Standard)
Source: Nursing Standard - September 28, 2016 Category: Nursing Authors: Carr A Tags: Nurs Stand Source Type: research

Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age.
CONCLUSIONS: There is no convincing evidence that vitamin A supplementation for infants one to six months of age results in a reduction in infant mortality or morbidity in low- and middle-income countries. There is an increased risk of bulging fontanelle with vitamin A supplementation in this age group; however, there were no reported subsequent complications because of this adverse effect. PMID: 27681486 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - September 28, 2016 Category: Journals (General) Authors: Imdad A, Ahmed Z, Bhutta ZA Tags: Cochrane Database Syst Rev Source Type: research

IFN- γ Blocks Development of an Asthma Phenotype in Rhinovirus-infected Baby Mice by Inhibiting ILC2s.
IFN-γ Blocks Development of an Asthma Phenotype in Rhinovirus-infected Baby Mice by Inhibiting ILC2s. Am J Respir Cell Mol Biol. 2016 Sep 28; Authors: Han M, Hong JY, Jaipalli S, Rajput C, Lei J, Hinde JL, Chen Q, Hershenson NM, Bentley JK, Hershenson MB Abstract Early-life wheezing-associated infections with rhinovirus (RV) have been associated with asthma development in children. We have shown that RV infection of six day-old mice induces mucous metaplasia and airways hyperresponsiveness which is dependent on IL-13, IL-25 and type 2 innate lymphoid cells (ILC2s). Infection of immature mice fails to...
Source: American Journal of Respiratory Cell and Molecular Biology - September 28, 2016 Category: Molecular Biology Authors: Han M, Hong JY, Jaipalli S, Rajput C, Lei J, Hinde JL, Chen Q, Hershenson NM, Bentley JK, Hershenson MB Tags: Am J Respir Cell Mol Biol Source Type: research

Risk factors for overnight respiratory events following sedation for magnetic resonance imaging in children with sleep apnea.
CONCLUSION: Ninety percent of children with sleep apnea admitted for overnight observation following sedated MRI did not have an ORE. AHI, anesthesia complications, and NIV use may help target higher-risk patients and avoid unnecessary hospitalizations. PMID: 27683261 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 28, 2016 Category: Sleep Medicine Authors: Trost MJ, Cowell M, Cannon J, Mitchell K, Waloff K, Avila H, Chand S, Russell CJ Tags: Sleep Breath Source Type: research

Does a large abdominal wall defect affect lung growth?
Respiratory distress in babies with large abdominal wall defects suggests a relationship to decreased diaphragmatic movement. We evaluated pulmonary development in a fetal lamb gastroschisis model. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - September 28, 2016 Category: Surgery Authors: Juma Obayashi, Kunihide Tanaka, Junki Koike, Yasuji Seki, Hideki Nagae, Shutaro Manabe, Kei Ohyama, Jane Zuccollo, Masayuki Takagi, Kevin C. Pringle, Hiroaki Kitagawa Source Type: research

Impulse oscillometry in the assessment of asthmatic children and adolescents: from a narrative to a systematic review
Diagnosis and management of asthma often relies mostly on symptoms because spirometry is not always reliable in some age groups, such as preschoolers. It is unclear whether impulse oscillometry (IOS) can supplement or replace spirometry. Available reports suggest that IOS has been applied with success in asthmatic children and adolescents to assess exacerbations, level of control, severity and response to treatment in the short and long term. Very few studies using adequate sample sizes and methods have been performed comparing the accuracy of IOS to spirometry for the diagnosis of asthma. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - September 28, 2016 Category: Respiratory Medicine Authors: Karoliny dos Santos, L ílian L. Fausto, Paulo A.M. Camargos, Maicon R. Kviecinski, Jane da Silva Source Type: research

Involvement of NF- κB in Regulation of Actinobacillus pleuropneumoniae Exotoxin ApxI-Induced Proinflammatory Cytokine Production in Porcine Alveolar Macrophages
Publication date: Available online 28 September 2016 Source:Veterinary Microbiology Author(s): Chiung-Wen Hsu, Siou-Cen Li, Nai-Yun Chang, Zeng-Weng Chen, Jiunn-Wang Liao, Ter-Hsin Chen, Jyh-Perng Wang, Jiunn-Horng Lin, Shih-Ling Hsuan Actinobacillus pleuropneumoniae is a crucial respiratory pathogen that causes fibrinous, hemorrhagic, necrotizing pleuropneumonia in pigs. A. pleuropneumoniae exotoxins (ApxI to IV) are the major virulence factors contributing to A. pleuropneumoniae pathogenesis. Previously, we demonstrated that ApxI induces the expression of proinflammatory cytokines in porcine alveolar macrophages (PAMs) ...
Source: Veterinary Microbiology - September 28, 2016 Category: Veterinary Research Source Type: research

Comparison of serum amyloid A in horses with infectious and non-infectious respiratory diseases
The acute phase protein serum amyloid A (SAA) has been shown to be a useful inflammatory parameter in the horse, but studies showing SAA responses to specific respiratory disease etiologies is limited. The goal of this study was to evaluate SAA responses in horses with infectious and non-infectious respiratory diseases as well as healthy, control horses. Two hundred and seven horses were grouped into the following categories: equine influenza virus (EIV), equine herpesvirus-4 (EHV-4), Streptococcus equi subspecies equi (S. (Source: Journal of Equine Veterinary Science)
Source: Journal of Equine Veterinary Science - September 28, 2016 Category: Veterinary Research Authors: Molly Viner, Melissa Mazan, Daniela Bedenice, Samantha Mapes, Nicola Pusterla Tags: Short Communication Source Type: research

Mitogenic equine isolates of Streptococcus zooepidemicus from North America host superantigen genes similar to those hosted in Europe
Streptococcus equi subsp. zooepidemicus (Sz) is an important opportunist pathogen of the equine respiratory and reproductive tracts. It is highly variable with respect to sequence type (ST) and virulence factors including SzP and SzM. Recent studies in the UK have shown that many Sz strains host genes for mitogenic superantigens including szeF, N, P and seeI, L, M. The aims of the present study were to estimate the prevalence of mitogenicity in equine Sz in North America and establish whether mitogenicity is more likely to be associated with isolates from a specific site of infection. (Source: Journal of Equine Veterinary Science)
Source: Journal of Equine Veterinary Science - September 28, 2016 Category: Veterinary Research Authors: Sridhar Velineni, Abhineet S. Sheoran, Cormac C. Breathnach, Nicola L. Rash, Romain Paillot, John F. Timoney Tags: Original Research Source Type: research

The Role of Caffeine in Noninvasive Respiratory Support
Caffeine is one of the most commonly prescribed medications in preterm neonates and is widely used to treat or prevent apnea of prematurity. Caffeine therapy is safe, effectively decreases apnea, and improves short- and long-term outcomes in preterm infants. In this review, the authors summarize the role of caffeine therapy for preterm infants receiving noninvasive respiratory support. As caffeine is already widely used, recent data are summarized that may guide clinicians in optimizing the use of caffeine therapy, with a review of the timing of initiation, dose, and duration of therapy. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - September 28, 2016 Category: Perinatology & Neonatology Authors: Nicole R. Dobson, Ravi Mangal Patel Source Type: research

Nationwide Distribution of Bovine Influenza D Virus Infection in Japan
by Taisuke Horimoto, Takahiro Hiono, Hirohisa Mekata, Tomoha Odagiri, Zhihao Lei, Tomoya Kobayashi, Junzo Norimine, Yasuo Inoshima, Hirokazu Hikono, Kenji Murakami, Reiichiro Sato, Hironobu Murakami, Masahiro Sakaguchi, Kazunori Ishii, Takaaki Ando, Kounosuke Otomaru, Makoto Ozawa, Yoshihiro Sakoda, Shin Murakami Cattle are major reservoirs of the provisionally named influenza D virus, which is potentially involved in the bovine respiratory disease complex. Here, we conducted a serological survey for the influenza D virus in Japan, using archived bovine serum samples collected during 2010–2016 from sever al herds of app...
Source: PLoS One - September 28, 2016 Category: Biomedical Science Authors: Taisuke Horimoto Source Type: research

SDHA mutation with dominant transmission results in complex II deficiency with ocular, cardiac, and neurologic involvement
Isolated defects of the mitochondrial respiratory complex II (succinate dehydrogenase, SDH) are rare, accounting for approximately 2% of all respiratory chain deficiency diagnoses. Here, we report clinical and molecular investigations of three family members with a heterozygous mutation in the large flavoprotein subunit SDHA previously described to cause complex II deficiency. The index patient presented with bilateral optic atrophy and ocular movement disorder, a progressive polyneuropathy, psychiatric involvement, and cardiomyopathy. Two of his children presented with cardiomyopathy and methylglutaconic aciduria in early...
Source: American Journal of Medical Genetics Part A - September 28, 2016 Category: Genetics & Stem Cells Authors: Carolina Courage, Christopher B. Jackson, Dagmar Hahn, Liliya Euro, Jean ‐Marc Nuoffer, Sabina Gallati, André Schaller Tags: Clinical Report Source Type: research

Effect of Glycemic Index of a Pre-exercise Meal on Endurance Exercise Performance: A Systematic Review and Meta-analysis
ConclusionThere was no clear benefit of consuming a LGI pre-exercise meal for endurance performance regardless of carbohydrate ingestion during exercise. (Source: Sports Medicine)
Source: Sports Medicine - September 28, 2016 Category: Sports Medicine Source Type: research

Pulmonary hypertension secondary to pulmonary veno-occlusive disease complicated by right heart failure, hypotension and acute kidney injury
Publication date: Available online 27 September 2016 Source:Respiratory Medicine Case Reports Author(s): Nima Golzy, Stuti Fernandes, Justin Sharim, Rikin Tank, Henry D. Tazelaar, Howard E. Epstein, Victor Tapson, Antoine Hage Pulmonary veno-occlusive disease (PVOD) is rare condition which can lead to severe pulmonary hypertension, right ventricular dysfunction, and cardiopulmonary failure. The diagnosis of PVOD can be challenging due to its nonspecific symptoms and its similarity to idiopathic pulmonary arterial hypertension and interstitial lung disease in terms of diagnostic findings. This case describes a 57 year old ...
Source: Respiratory Medicine Case Reports - September 28, 2016 Category: Respiratory Medicine Source Type: research

Pulmonary tuberculosis followed by sarcoidosis in an HIV-infected patient: A case report and a simplified diagnostic flowchart for diagnosis and treatment of sarcoidosis
Publication date: Available online 28 September 2016 Source:Respiratory Medicine Case Reports Author(s): P. Mencarini, R. Bellagamba, A. Oliva, P. Ghirga, M.L. Giancola, A. Corpolongo, T. Ascoli Bartoli, P. De Nardo, A. Baiocchini, F. Del Nonno, P. Narciso, E. Nicastri The diagnosis of sarcoidosis in a patient living with HIV infection is an uncommon event and a challenge for clinicians. Clinical manifestations are variable and fluctuating depending to adherence to ARV therapy and to the level of CD4 count. We analyze here one chronic case in which sarcoidosis appeared clinically two years after pulmonary tuberculosis. Th...
Source: Respiratory Medicine Case Reports - September 28, 2016 Category: Respiratory Medicine Source Type: research