The Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum (Green-top Guideline No. 69)
BJOG. 2024 Feb 4. doi: 10.1111/1471-0528.17739. Online ahead of print.ABSTRACTAn objective and validated index of nausea and vomiting such as the Pregnancy-Unique Quantification of Emesis (PUQE) and HyperEmesis Level Prediction (HELP) tools can be used to classify the severity of NVP and HG. [Grade C] Ketonuria is not an indicator of dehydration and should not be used to assess severity. [Grade A] There are safety and efficacy data for first line antiemetics such as anti (H1) histamines, phenothiazines and doxylamine/pyridoxine (Xonvea®) and they should be prescribed initially when required for NVP and HG (Appendix III). ...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 4, 2024 Category: OBGYN Authors: Catherine Nelson-Piercy Caitlin Dean Manjeet Shehmar Roger Gadsby Margaret O'Hara Kenneth Hodson Melanie Nana Royal College of Obstetricians and Gynaecologists Source Type: research

British Gynaecological Cancer Society (BGCS) Vulval Cancer Guidelines: An Update on Recommendations for Practice 2023
Recommendations are graded as per the Royal College of Obstetricians and Gynaecologists document. Clinical Governance Advice No. 1: Guidance for the Development of RCOG Green-top Guidelines, available on the RCOG website at: (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - November 15, 2023 Category: OBGYN Authors: Jo Morrison, Peter Baldwin, Louise Hanna, Adrian Andreou, Lynn Buckley, Lisa Durrant, Katharine Edey, Asma Faruqi, Christina Fotopoulou, Raji Ganesan, Kathryn Hillaby, Alexandra Taylor Tags: Expert Opinion Source Type: research

Placental growth factor testing at 19-23  weeks of gestation as a guide to subsequent care in pregnancy: A prospective observational study
CONCLUSIONS: Clinical risk factor screening has a high screen-positive rate and a poor detection of adverse outcomes. False positives cannot be reduced by PlGF testing at 19-23 weeks of gestation; therefore, this cannot be recommended as a useful strategy on its own.PMID:37873570 | DOI:10.1111/1471-0528.17684 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 24, 2023 Category: OBGYN Authors: Laura A Magee Argyro Syngelaki Ranjit Akolekar Peter von Dadelszen Kypros H Nicolaides Source Type: research

Placental growth factor testing at 19-23  weeks of gestation as a guide to subsequent care in pregnancy: A prospective observational study
CONCLUSIONS: Clinical risk factor screening has a high screen-positive rate and a poor detection of adverse outcomes. False positives cannot be reduced by PlGF testing at 19-23 weeks of gestation; therefore, this cannot be recommended as a useful strategy on its own.PMID:37873570 | DOI:10.1111/1471-0528.17684 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 24, 2023 Category: OBGYN Authors: Laura A Magee Argyro Syngelaki Ranjit Akolekar Peter von Dadelszen Kypros H Nicolaides Source Type: research

A systematic review and meta-synthesis of qualitative studies on childbirth perineal trauma for the development of a Core Outcome Set
About 85% of women who have a vaginal birth sustain some degree of perineal trauma [1]. Maternal injury during vaginal childbirth refers to any form of physical trauma [2]. Such injuries may have an impact on the relevant anatomical tissues and structures such as the perineal muscles, genitalia, external and internal anal sphincters, or rectal wall [2]. Injuries can occur either spontaneously or iatrogenically, via episiotomy or perineotomy. According to the perineal injury classification published by the Royal College of Obstetricians and Gynaecologists (RCOG), the International Continence Society (ICS) and the Internatio...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 11, 2023 Category: OBGYN Authors: Maria Patricia Roman, Shaurya Aggarwal, Stergios K Doumouchtsis Tags: Review article Source Type: research

Projected impact of guidelines on incidence of venous thromboembolism after cesarean delivery in the United States
CONCLUSIONS: Adoption of different guidelines would have notably varying implications for clinical practice and potential for alteration of the national rate of VTE following CD.PMID:37659859 | DOI:10.1016/j.jtha.2023.08.010 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - September 2, 2023 Category: Hematology Authors: Jerome J Federspiel Lauren E Wein Ryan Duggal Evan R Myers Kimberly A Boggess Andra H James Source Type: research

Projected impact of guidelines on incidence of venous thromboembolism after cesarean delivery in the United States
CONCLUSIONS: Adoption of different guidelines would have notably varying implications for clinical practice and potential for alteration of the national rate of VTE following CD.PMID:37659859 | DOI:10.1016/j.jtha.2023.08.010 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - September 2, 2023 Category: Hematology Authors: Jerome J Federspiel Lauren E Wein Ryan Duggal Evan R Myers Kimberly A Boggess Andra H James Source Type: research

Risk Assessment Model for Postpartum Venous Thromboembolism Prevention in Patients with Systemic Lupus Erythematosus
Conclusion These data reveal a need to improve upon providing postpartum VTE prophylaxis to SLE patients not in remission while also recognizing a diagnosis of SLE alone should not equate with active disease. Moreover, SLE patients in remission may still warrant VTE prophylaxis if other non-SLE-related risk factors are present. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - July 20, 2023 Category: Perinatology & Neonatology Authors: Griffin, Myah M. Engel, Alexis Mehta-Lee, Shilpi S. Nusbaum, Julie Golpanian, Michael Izmirly, Peter Belmont, H. Michael Buyon, Jill P. Tags: SMFM Fellowship Series Article Source Type: research

Not too fast, not too slow: A review of historical trends in vaginal breech time management
CONCLUSION: Clear, evidence-based guidance should be provided in breech training materials to avoid unnecessary hypoxic injuries, and this guidance should be rigorously evaluated.PMID:37390754 | DOI:10.1016/j.ejogrb.2023.06.015 (Source: Reproductive Biology)
Source: Reproductive Biology - June 30, 2023 Category: Reproduction Medicine Authors: Jacana Bresson Keelie Christie Shawn Walker Source Type: research

Not too fast, not too slow: A review of historical trends in vaginal breech time management
CONCLUSION: Clear, evidence-based guidance should be provided in breech training materials to avoid unnecessary hypoxic injuries, and this guidance should be rigorously evaluated.PMID:37390754 | DOI:10.1016/j.ejogrb.2023.06.015 (Source: Reproductive Biology)
Source: Reproductive Biology - June 30, 2023 Category: Reproduction Medicine Authors: Jacana Bresson Keelie Christie Shawn Walker Source Type: research

Recurrent MiscarriageGreen-top Guideline No. 17
BJOG. 2023 Jun 19. doi: 10.1111/1471-0528.17515. Online ahead of print.ABSTRACTIn this guideline, recurrent miscarriage has been defined as three or more first trimester miscarriages. However, clinicians are encouraged to use their clinical discretion to recommend extensive evaluation after two first trimester miscarriages, if there is a suspicion that the miscarriages are of pathological and not of sporadic nature. Women with recurrent miscarriage should be offered testing for acquired thrombophilia, particularly for lupus anticoagulant and anticardiolipin antibodies, prior to pregnancy. [Grade C] Women with second trimes...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - June 19, 2023 Category: OBGYN Authors: Lesley Regan Rajendra Rai Sotirios Saravelos Tin-Chiu Li Royal College of Obstetricians and Gynaecologists Source Type: research

Recurrent MiscarriageGreen-top Guideline No. 17
BJOG. 2023 Jun 19. doi: 10.1111/1471-0528.17515. Online ahead of print.ABSTRACTIn this guideline, recurrent miscarriage has been defined as three or more first trimester miscarriages. However, clinicians are encouraged to use their clinical discretion to recommend extensive evaluation after two first trimester miscarriages, if there is a suspicion that the miscarriages are of pathological and not of sporadic nature. Women with recurrent miscarriage should be offered testing for acquired thrombophilia, particularly for lupus anticoagulant and anticardiolipin antibodies, prior to pregnancy. [Grade C] Women with second trimes...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - June 19, 2023 Category: OBGYN Authors: Lesley Regan Rajendra Rai Sotirios Saravelos Tin-Chiu Li Royal College of Obstetricians and Gynaecologists Source Type: research

Low-dose aspirin therapy for the prevention of preeclampsia: time to reconsider our recommendations?
The American College of Obstetricians and Gynecologists recommends initiation of 81 mg of aspirin daily for women at risk of preeclampsia between 12 and 28 weeks ’ gestation, optimally before 16 weeks, with continuation until delivery. The World Health Organization recommends that 75 mg of aspirin should be initiated before 20 weeks of gestation for women at high risk of preeclampsia. Both the Royal College of Obstetricians and Gynaecologists and the Natio nal Institute of Health and Care Excellence quality statement on “Antenatal Assessment of Pre-eclampsia Risk” request that healthcare providers prescribe low-dose ...
Source: American Journal of Obstetrics and Gynecology - April 27, 2023 Category: OBGYN Authors: Rebecca Horgan, Yara Hage Diab, Jerri Waller, Alfred Abuhamad, George Saade Tags: Clinical Opinion Source Type: research

ChatGPT Outscored Human Candidates in a Virtual Objective Structured Clinical Examination (OSCE) in Obstetrics and Gynecology
Natural language processing is a form of artificial intelligence that allows human users to interface with a machine without using complex code. The ability of natural language processing systems such as ChatGPT to successfully engage with healthcare systems requiring fluid reasoning, specialist data interpretation, and empathetic communication in an unfamiliar and evolving environment is poorly studied. We tested whether the ChatGPT interface could engage with and complete a mock Objective Structured Clinical Examination simulating assessment for Membership of the Royal College of Obstetricians and Gynaecologists. (Source...
Source: American Journal of Obstetrics and Gynecology - April 21, 2023 Category: OBGYN Authors: Sarah W. LI, Matthew W. Kemp, Susan J.S. Logan, Pooja Sharma Dimri, Navkaran Singh, Citra N.Z. Mattar, Pradip Dashraath, Harshaana Ramlal, Aniza P. Mahyuddin, Suren Kanayan, Sean W.D. Carter, Serene P.T. Thain, Erin L. Fee, Sebastian E. Illanes, Mahesh A. Tags: Original Research: Education Source Type: research

ChatGPT outscored human candidates in a virtual objective structured clinical examination in obstetrics and gynecology
This study investigated whether the ChatGPT interface could engage with and complete a mock objective structured clinical examination simulating assessment for membership of the Royal College of Obstetricians and Gynaecologists. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 21, 2023 Category: OBGYN Authors: Sarah W. Li, Matthew W. Kemp, Susan J.S. Logan, Pooja Sharma Dimri, Navkaran Singh, Citra N.Z. Mattar, Pradip Dashraath, Harshaana Ramlal, Aniza P. Mahyuddin, Suren Kanayan, Sean W.D. Carter, Serene P.T. Thain, Erin L. Fee, Sebastian E. Illanes, Mahesh A. Tags: Original Research Source Type: research