Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia
CONCLUSION: OSSN may arise in the setting of chronic inflammation on the ocular surface. Identification of the tumor can be challenging in these cases, and HR-OCT can be a key diagnostic tool in detecting OSSN.PMID:38432640 | DOI:10.1016/j.jtos.2024.02.006 (Source: The Ocular Surface)
Source: The Ocular Surface - March 3, 2024 Category: Opthalmology Authors: Sofia De Arrigunaga Sarah Wall Despoina Theotoka Asaf Friehmann Matthew Camacho Sander Dubovy Anat Galor Carol L Karp Source Type: research

Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia
CONCLUSION: OSSN may arise in the setting of chronic inflammation on the ocular surface. Identification of the tumor can be challenging in these cases, and HR-OCT can be a key diagnostic tool in detecting OSSN.PMID:38432640 | DOI:10.1016/j.jtos.2024.02.006 (Source: The Ocular Surface)
Source: The Ocular Surface - March 3, 2024 Category: Opthalmology Authors: Sofia De Arrigunaga Sarah Wall Despoina Theotoka Asaf Friehmann Matthew Camacho Sander Dubovy Anat Galor Carol L Karp Source Type: research

Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia
CONCLUSION: OSSN may arise in the setting of chronic inflammation on the ocular surface. Identification of the tumor can be challenging in these cases, and HR-OCT can be a key diagnostic tool in detecting OSSN.PMID:38432640 | DOI:10.1016/j.jtos.2024.02.006 (Source: The Ocular Surface)
Source: The Ocular Surface - March 3, 2024 Category: Opthalmology Authors: Sofia De Arrigunaga Sarah Wall Despoina Theotoka Asaf Friehmann Matthew Camacho Sander Dubovy Anat Galor Carol L Karp Source Type: research

Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia
CONCLUSION: OSSN may arise in the setting of chronic inflammation on the ocular surface. Identification of the tumor can be challenging in these cases, and HR-OCT can be a key diagnostic tool in detecting OSSN.PMID:38432640 | DOI:10.1016/j.jtos.2024.02.006 (Source: The Ocular Surface)
Source: The Ocular Surface - March 3, 2024 Category: Opthalmology Authors: Sofia De Arrigunaga Sarah Wall Despoina Theotoka Asaf Friehmann Matthew Camacho Sander Dubovy Anat Galor Carol L Karp Source Type: research

S100A9 exacerbates the inflammation in rosacea via TLR4/MyD88/NF- κB signaling pathway
Rosacea is a chronic inflammatory skin disorder characterized by immune response-dependent erythema and pustules. S100 calcium binding protein A9 (S100A9), a pro-inflammatory alarmin, has been associated with various inflammation-related diseases. However, the specific role of S100A9 in rosacea remains unexplored. Therefore, our objective was to unravel the role of S100A9 in the pathogenesis of rosacea and its underlying molecular mechanisms. Here, we show that expression levels of S100A9 were elevated in both the lesions and serum of PPR patients, as well as in lesions of the LL37-induced rosacea-like mouse model. (Source...
Source: Journal of Investigative Dermatology - March 3, 2024 Category: Dermatology Authors: Yan Le, Jiawen Zhang, Yi Lin, Jie Ren, Leihong Xiang, Chengfeng Zhang Tags: Original Article Source Type: research

S100A9 Exacerbates the Inflammation in Rosacea through Toll-Like Receptor 4/MyD88/NF- κB Signaling Pathway
In this study, we show that expression levels of S100A9 were elevated in both the lesions and serum of patients with papulopustular rosacea as well as in lesions of the LL37-induced rosacea-like mouse model. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - March 3, 2024 Category: Dermatology Authors: Yan Le, Jiawen Zhang, Yi Lin, Jie Ren, Leihong Xiang, Chengfeng Zhang Tags: Original Article Source Type: research

Corrigendum: OPN promotes pro-inflammatory cytokine expression via ERK/JNK pathway and M1 macrophage polarization in Rosacea
(Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 29, 2024 Category: Allergy & Immunology Source Type: research

Microencapsulated Benzoyl Peroxide for Rosacea in Context: A Review of the Current Treatment Landscape
AbstractRosacea, a chronic skin condition affecting millions of people in the USA, leads to significant social and professional stigmatization. Effective management strategies are crucial to alleviate symptoms and improve patients ’ quality of life. Encapsulated benzoyl peroxide 5% (E-BPO 5%) is a newly FDA-approved topical treatment for rosacea that shows promise in enhancing therapeutic response and minimizing skin irritation. This review aims to assess the role of recently FDA approved E-BPO 5% in the current treatment l andscape for rosacea management, as it is not yet included in clinical guidelines that predominant...
Source: Drugs - February 29, 2024 Category: Drugs & Pharmacology Source Type: research

A Case of Tinea Faciei due to Trichophyton indotineae with Steroid Rosacea Related to Topical Over-The-Counter Drugs Purchased Outside of Japan
Med Mycol J. 2024;65(1):23-26. doi: 10.3314/mmj.23-00014.ABSTRACTA Filipino woman in her forties had facial erythema that was being self-treated with over-the-counter (OTC) drugs purchased outside of Japan. The drugs included clobetasol propionate, antibiotic, and antifungal components. Her facial erythema symptoms were worse during summertime. KOH direct examination of annular erythema was positive for fungal hyphae and negative for Demodex folliculorum. Fungal culture revealed Trichophyton indotineae based on internal transcribed spacer sequence analysis. Minimal inhibitory concentration for terbinafine was 0.06 µg/mL. ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Norihito Fukada Hisashi Kobayashi Manabu Nakazono Keita Ohyachi Akinori Takeda Takashi Yaguchi Miyuki Okada Tomotaka Sato Source Type: research