The associations between gut microbiota and inflammatory skin diseases: a bi-directional two-sample Mendelian randomization study
ConclusionsIn summary, this study provided evidence for the causality between GM and inflammatory skin diseases. These findings suggested that supplementing specific bacterial taxa may be an effective therapy for AD, PSO, and ROS. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 2, 2024 Category: Allergy & Immunology Source Type: research

Assessment of the Reliability and Clinical Applicability of ChatGPT ’s Responses to Patients’ Common Queries About Rosacea
(Source: Patient Preference and Adherence)
Source: Patient Preference and Adherence - January 30, 2024 Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research

Rosacea: Practical Guidance and Challenges for Clinical Management
Clin Cosmet Investig Dermatol. 2024 Jan 23;17:175-190. doi: 10.2147/CCID.S391705. eCollection 2024.ABSTRACTRosacea is a common chronic dermatosis. Clinically, rosacea can present with flushing, erythema, papules, pustules, telangiectasias, phymatous changes, pruritus, burning, and stinging. In 2017, the National Rosacea Society Expert Committee recommended a phenotype-based classification for therapy. In this review, we identify monotherapies and multimodal treatment approaches for the clinical management of rosacea including topical, systemic, laser and light, alternative, and combination therapies.PMID:38283794 | PMC:PMC...
Source: Clinical, Cosmetic and Investigational Dermatology - January 29, 2024 Category: Dermatology Authors: Cassidy Nguyen Guilherme Kuceki Michael Birdsall Dev Ram Sahni Vikram Nath Sahni Christopher M Hull Source Type: research

The Association Between Acne Vulgaris, Acne Vulgaris with Nonspecific Facial Dermatitis, and < em > Demodex < /em > Mite Presence
CONCLUSION: Demodex prevalence and high Demodex density rate are not associated with acne vulgaris. Still, it is associated with acne and nonspecific facial dermatitis, particularly in patients with patchy redness, dry, scaly skin, roughness, insect bite-like papules, and flushing.PMID:38283791 | PMC:PMC10813226 | DOI:10.2147/CCID.S450540 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 29, 2024 Category: Dermatology Authors: Anon Paichitrojjana Thep Chalermchai Source Type: research

The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications
Postepy Dermatol Alergol. 2023 Dec;40(6):716-724. doi: 10.5114/ada.2023.133955. Epub 2024 Jan 8.ABSTRACTAzelaic acid (AZA) is a naturally occurring saturated dicarboxylic acid whose topical application has found multiple uses in dermatology. Its anti-inflammatory, antioxidant and antimicrobial properties against Propionibacterium acne are currently used in the treatment of various types of acne such as rosacea and acne vulgaris. AZA is an inhibitor of tyrosinase, mitochondrial respiratory chain enzymes and DNA synthesis, and is a scavenger of harmful free radicals and inhibits the production of reactive oxygen species by n...
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Natalia Sauer Ma łgorzata Oślizło Marta Brzostek Julianna Wolska Katarzyna Lubaszka Katarzyna Kar łowicz-Bodalska Source Type: research