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Cross-cultural validation of the RosaQoL scale in Spanish language
CONCLUSIONS: The Spanish version of the RosaQoL scale exhibits psychometric characteristics, which are similar to the original scale. Also, the RosaQoL scale is useful to assess the quality of life of patients with rosacea.PMID:38382749 | DOI:10.1016/j.ad.2024.02.014 (Source: Actas Dermo-Sifiliograficas)
Source: Actas Dermo-Sifiliograficas - February 21, 2024 Category: Dermatology Authors: M Salleras Redonnet J Del Pozo Losada M Ribera Pibernat Source Type: research

Microbiome: Role in Inflammatory Skin Diseases
J Inflamm Res. 2024 Feb 15;17:1057-1082. doi: 10.2147/JIR.S441100. eCollection 2024.ABSTRACTAs the body's largest organ, the skin harbors a highly diverse microbiota, playing a crucial role in resisting foreign pathogens, nurturing the immune system, and metabolizing natural products. The dysregulation of human skin microbiota is implicated in immune dysregulation and inflammatory responses. This review delineates the microbial alterations and immune dysregulation features in common Inflammatory Skin Diseases (ISDs) such as psoriasis, rosacea, atopic dermatitis(AD), seborrheic dermatitis(SD), diaper dermatitis(DD), and Mal...
Source: Cell Research - February 20, 2024 Category: Cytology Authors: Xue-Er Zhang Pai Zheng Sheng-Zhen Ye Xiao Ma E Liu Yao-Bin Pang Qing-Ying He Yu-Xiao Zhang Wen-Quan Li Jin-Hao Zeng Jing Guo Source Type: research

Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF- κB signaling pathway
In this study, bioinformatics analyses showed that the mechanisms of rosacea and the pharmacological targets of OA were highly overlapped. Subsequently, it was shown that the administration of OA resulted in a notable amelioration of rosacea-like skin lesions, as evidenced by a reduction in immune cell infiltration, modulation of cytokine production, and inhibition of angiogenesis. Plus, it was shown that OA effectively suppressed the generation of ROS generated by LL-37, as well as the subsequent activation of NF-κB signaling pathway. To explore further, we found that OA inhibited LL-37-induced ROS production via SIRT3-S...
Source: International Immunopharmacology - February 16, 2024 Category: Allergy & Immunology Authors: Chunmei Feng Haiyan Zhang Peiru Wang Linglin Zhang Xiaojing Liu Guorong Yan Yu Yan Jin Yang Jia Liu Fei Tan Xiuli Wang Qingyu Zeng Source Type: research

A Comparative Study on Clinico-Histopathological Features of Granulomatous Rosacea and Lupus Miliaris Disseminatus Faciei
Ann Dermatol. 2024 Feb;36(1):58-61. doi: 10.5021/ad.22.229.NO ABSTRACTPMID:38325436 | PMC:PMC10861309 | DOI:10.5021/ad.22.229 (Source: Annals of Dermatology)
Source: Annals of Dermatology - February 7, 2024 Category: Dermatology Authors: So Hee Park Sang Woo Ahn Seung Hee Jang Seong Min Hong Woo Jung Jin Jung Eun Seol So Young Jung Hyojin Kim Source Type: research

Consensus Report on Truncal Acne: The Korean Acne and Rosacea Society Experts Panel
CONCLUSION: Our study has yielded valuable insights into the epidemiology, clinical manifestations, diagnosis, treatment, and quality of life of patients with truncal acne. We anticipate that this study will inspire further comprehensive research for individuals with truncal acne.PMID:38325432 | PMC:PMC10861305 | DOI:10.5021/ad.23.057 (Source: Annals of Dermatology)
Source: Annals of Dermatology - February 7, 2024 Category: Dermatology Authors: Joo Yeon Ko Chang Hwa Song Kwang Joong Kim Nack In Kim Jung Eun Kim Hei Sung Kim Young Suck Ro Kui Young Park Mi-Youn Park Dae Hun Suh Kihyuck Shin Min Kyung Shin Hyo Hyun Ahn Woo Jin Lee Weon Ju Lee Ju Hee Lee Jee Bum Lee Hae Woong Lee Hee Jung Lee Min S Source Type: research