Rapid Rituximab: An Inpatient Pilot Project to Increase Education and Use Among Oncology Nurses
Clin J Oncol Nurs. 2022 Jul 25;26(4):433-437. doi: 10.1188/22.CJON.433-437.ABSTRACT&nbsp.PMID:35939733 | DOI:10.1188/22.CJON.433-437 (Source: Clinical Journal of Oncology Nursing)
Source: Clinical Journal of Oncology Nursing - August 8, 2022 Category: Nursing Authors: Casey Schade Source Type: research

Rapid Rituximab: An Inpatient Pilot Project to Increase Education and Use Among Oncology Nurses
Clin J Oncol Nurs. 2022 Jul 25;26(4):433-437. doi: 10.1188/22.CJON.433-437.ABSTRACT&nbsp.PMID:35939733 | DOI:10.1188/22.CJON.433-437 (Source: Clinical Journal of Oncology Nursing)
Source: Clinical Journal of Oncology Nursing - August 8, 2022 Category: Nursing Authors: Casey Schade Source Type: research

Rapid Rituximab: An Inpatient Pilot Project to Increase Education and Use Among Oncology Nurses
Clin J Oncol Nurs. 2022 Jul 25;26(4):433-437. doi: 10.1188/22.CJON.433-437.ABSTRACT&nbsp.PMID:35939733 | DOI:10.1188/22.CJON.433-437 (Source: Clinical Journal of Oncology Nursing)
Source: Clinical Journal of Oncology Nursing - August 8, 2022 Category: Nursing Authors: Casey Schade Source Type: research

Rapid Rituximab: An Inpatient Pilot Project to Increase Education and Use Among Oncology Nurses
Clin J Oncol Nurs. 2022 Jul 25;26(4):433-437. doi: 10.1188/22.CJON.433-437.ABSTRACT&nbsp.PMID:35939733 | DOI:10.1188/22.CJON.433-437 (Source: Clinical Journal of Oncology Nursing)
Source: Clinical Journal of Oncology Nursing - August 8, 2022 Category: Nursing Authors: Casey Schade Source Type: research

Site-selective sulfation of N-glycans by human GlcNAc-6-O-sulfotransferase 1 (CHST2) and chemoenzymatic synthesis of sulfated antibody glycoforms
We report here the first in vitro enzymatic sulfation of biantennary complex type N-glycans by recombinant human CHST2 (GlcNAc-6-O-sulfotransferase 1, GlcNAc6ST-1). We found that the sulfotransferase showed high antennary preference and could selectively sulfate the GlcNAc moiety located on the Manα1,3Man arm of the biantennary N-glycan. The glycan chain was further elongated by bacterial β1,4 galactosyltransferase from Neiserria meningitidis and human β1,4 galactosyltransferase IV(B4GALT4), which led to the formation of different sulfated N-glycans. Using rituximab as a model IgG antibody, we further demonstrated t...
Source: Bioorganic Chemistry - August 8, 2022 Category: Chemistry Authors: Kun Huang Chao Li Guanghui Zong Sunaina Kiran Prabhu Digantkumar G Chapla Kelley W Moremen Lai-Xi Wang Source Type: research

Rapid Rituximab: An Inpatient Pilot Project to Increase Education and Use Among Oncology Nurses
Clin J Oncol Nurs. 2022 Jul 25;26(4):433-437. doi: 10.1188/22.CJON.433-437.ABSTRACT&nbsp.PMID:35939733 | DOI:10.1188/22.CJON.433-437 (Source: Clinical Journal of Oncology Nursing)
Source: Clinical Journal of Oncology Nursing - August 8, 2022 Category: Nursing Authors: Casey Schade Source Type: research

Site-selective sulfation of N-glycans by human GlcNAc-6-O-sulfotransferase 1 (CHST2) and chemoenzymatic synthesis of sulfated antibody glycoforms
We report here the first in vitro enzymatic sulfation of biantennary complex type N-glycans by recombinant human CHST2 (GlcNAc-6-O-sulfotransferase 1, GlcNAc6ST-1). We found that the sulfotransferase showed high antennary preference and could selectively sulfate the GlcNAc moiety located on the Manα1,3Man arm of the biantennary N-glycan. The glycan chain was further elongated by bacterial β1,4 galactosyltransferase from Neiserria meningitidis and human β1,4 galactosyltransferase IV(B4GALT4), which led to the formation of different sulfated N-glycans. Using rituximab as a model IgG antibody, we further demonstrated t...
Source: Bioorganic Chemistry - August 8, 2022 Category: Chemistry Authors: Kun Huang Chao Li Guanghui Zong Sunaina Kiran Prabhu Digantkumar G Chapla Kelley W Moremen Lai-Xi Wang Source Type: research

Rapid Rituximab: An Inpatient Pilot Project to Increase Education and Use Among Oncology Nurses
Clin J Oncol Nurs. 2022 Jul 25;26(4):433-437. doi: 10.1188/22.CJON.433-437.ABSTRACT&nbsp.PMID:35939733 | DOI:10.1188/22.CJON.433-437 (Source: Clinical Journal of Oncology Nursing)
Source: Clinical Journal of Oncology Nursing - August 8, 2022 Category: Nursing Authors: Casey Schade Source Type: research

Assessing the Role of Radiotherapy in Patients with Refractory or Relapsed High-Grade B-Cell Lymphomas Treated with CAR T-Cell Therapy
Non-Hodgkin lymphoma (NHL) is the most prevalent hematologic malignancy1, accounting for approximately 4.3% of all new cancers and 3.4% of all cancer deaths in the United States2. Diffuse large B-cell lymphoma (DLBCL) constitutes 30-40% of all NHL cases in the U.S.3. In the last few decades, the survival rates have improved to a 5-year relative survival rate of 63.9% in the United States and 55.4% in Europe4,5. The most common upfront treatment for patients with DLBCL is R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone), with select patients receiving consolidative radiation therapy (RT) follow...
Source: Radiotherapy and Oncology - August 8, 2022 Category: Radiology Authors: Hazim S. Ababneh, Jeremy S. Abramson, P. Connor Johnson, Chirayu G. Patel Tags: Review Article Source Type: research

Evaluation of serological response to anti-SARS-CoV-2 mRNA vaccination in hematological patients
ConclusionsOur data confirm reduced serological response in hematological patients after anti-SARS-CoV-2 vaccination. However, we found a great diversity of SARS-CoV-2 antibody response according to types of pathologies and therapies. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - August 8, 2022 Category: Allergy & Immunology Source Type: research

Interest of daratumumab in refractory AL amyloidosis in a 96-year-old patient
In conclusion, our case suggests that daratumumab is an effective and well-tolerated alternative to chemotherapy in the treatment af AL amyloidosis in very elderly patients.PMID:35934598 | DOI:10.1016/j.revmed.2022.07.013 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - August 7, 2022 Category: Internal Medicine Authors: G Vial A Lafargue P Merci é P Duffau E Ribeiro Source Type: research

Acquired Hemophilia A in a Patient With Multiple Sclerosis
Conclusion AHA should be suspected in any patient with new-onset bleeding in the presence of a prolonged activated partial thromboplastin time. Prompt diagnosis and treatment are important as AHA carries a high mortality rate.PMID:35933672 | DOI:10.7812/TPP/21.109 (Source: The Permanente journal)
Source: The Permanente journal - August 7, 2022 Category: General Medicine Authors: George K Sidarous Arya Mariam Roy Appalanaidu Sasapu Source Type: research

Interest of daratumumab in refractory AL amyloidosis in a 96-year-old patient
In conclusion, our case suggests that daratumumab is an effective and well-tolerated alternative to chemotherapy in the treatment af AL amyloidosis in very elderly patients.PMID:35934598 | DOI:10.1016/j.revmed.2022.07.013 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - August 7, 2022 Category: Internal Medicine Authors: G Vial A Lafargue P Merci é P Duffau E Ribeiro Source Type: research