The Efficacy and Safety of CT-P13 vs Infliximab in RA The Efficacy and Safety of CT-P13 vs Infliximab in RA
CT-P13, a biosimilar of reference infliximab, may be a safe and effective treatment option for patients with active rheumatoid arthritis.Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 9, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Promising rheumatoid arthritis therapy sarilumab accepted for EU review
A potentially promising new treatment for rheumatoidarthritis has just passed an important milestone on its path to regulatory approval. Sarilumab, a human monoclonal antibody intended for the treatment of adults with moderate to severely activerheumatoid arthritis, has had its marketing authorisation application accepted by the European Medicines Agency (EMA), bringing it one step closer to widespread availability. The benefits of the new therapy Developed by Sanofi and Regeneron Pharmaceuticals, sarilumab works by targeting the IL-6 receptor, which is known to play a key role in the joint damage and painful symptoms that...
Source: Arthritis Research UK - August 8, 2016 Category: Rheumatology Source Type: news

Mesoblast cell treatment shows promise in rheumatoid arthritis : study
(Reuters) - Mesoblast Ltd on Monday said its experimental stem-cell treatment led to significant improvements of symptoms and disease activity in patients whose rheumatoid arthritis had stopped being helped by widely used biotech medicines, according to data from a mid-stage trial. (Source: Reuters: Health)
Source: Reuters: Health - August 8, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

New arthritis jab ‘will relieve pain for acute sufferers’
A NEW fortnightly injection could provide relief from the crippling pain of rheumatoid arthritis, it was revealed yesterday. (Source: Daily Express - Health)
Source: Daily Express - Health - August 8, 2016 Category: Consumer Health News Source Type: news

How Much Omega-3 vs Omega-6
All the so-called “nutrition experts” telling us to eat unsaturated fats instead of saturated fats are missing the point. There are natural saturated fats that are perfectly healthy to eat… and manufactured unsaturated fats that are at the root cause of many of our health problems. That’s because it’s the ratio of omega-6 fats and omega-3 fats in our modern diet that’s actually the problem. Let me explain… Omega Fatty Acids In Our Diet Omega-6s are fatty acids commonly found in vegetable oils. That includes safflower, sunflower, corn, cottonseed, sesame and soybean. They’re...
Source: Al Sears, MD Natural Remedies - August 8, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Nutrition Source Type: news

Well: Arthritis Drug May Have Benefits Against Alzheimer ’ s
An inflammation-fighting drug for rheumatoid arthritis may offer protection against Alzheimer ’ s, a study suggests. (Source: NYT Health)
Source: NYT Health - August 4, 2016 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Alzheimer's Disease Featured Live Source Type: news

Generic biosimilar therapies for arthritis 'as effective as branded versions'
This study only applies to anti-TNFs, underlining the need for further research on whether other biosimilar products - such as biosimilar insulins - work as well as their branded counterparts. Nevertheless, the results show that rheumatoid arthritis patients at least can benefit from the availability of effective therapy options at a lower cost, meaning more people may be able to access the drugs without placing an excessive burden on healthcare services. Study leader Dr Caleb Alexander, co-director of the Johns Hopkins Center for Drug Safety and Effectiveness, said:"Hopefully this will encourage the brisk adoption of...
Source: Arthritis Research UK - August 2, 2016 Category: Rheumatology Source Type: news

Self-Reported Flares Predict Radiographic Progression in RA Self-Reported Flares Predict Radiographic Progression in RA
Are flares reported by rheumatoid arthritis patients predictors of radiographic progression?Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

' Generic' biologic drugs appear comparable to brand-name counterparts
Generic forms of a biologic drug used to treat rheumatoid arthritis, inflammatory bowel disease and psoriasis appear to be as safe and effective as their brand-name counterparts, a new analysis suggests. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 1, 2016 Category: Science Source Type: news

Rheumatoid arthritis: Can it affect the eyes?
Although rheumatoid arthritis is primarily a joint disease, it occasionally affects the eyes. (Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - August 1, 2016 Category: Consumer Health News Source Type: news

Potential new way to sway the immune system
A new international collaboration opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 1, 2016 Category: Science Source Type: news

Generic Biologic Drugs Seem as Effective as Originals
MONDAY, Aug. 1, 2016 -- Generic biologic drugs are similarly effective to brand-name counterparts in treating rheumatoid arthritis, inflammatory bowel disease and psoriasis, a new study says. Biologics are medications made from living cells. They... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 1, 2016 Category: Journals (General) Source Type: news

Found: A potential new way to sway the immune system
(Scripps Research Institute) A new international collaboration involving scientists at The Scripps Research Institute opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 1, 2016 Category: Biology Source Type: news

Synthetic vaccine particles immune tolerance mechanism published in Nature Nanotechnology
(The Yates Network) Preclinical studies show that Selecta Biosciences' proprietary immune therapies use a targeted mechanism of action to improve the efficacy and safety of biologic therapeutics and to address autoimmune diseases and allergies. The company is developing targeted antigen-specific immune therapies for rare and serious diseases. The data in Nature Nanotechnology support Selecta's lead clinical program, showing Selecta's SVP-Rapamycin induces antigen-specific immune tolerance and prevents the formation of anti-drug antibodies to biologic drugs, including pegsiticase (gout) and adalimumab (rheumatoid arthritis)...
Source: EurekAlert! - Cancer - August 1, 2016 Category: Cancer & Oncology Source Type: news

Amgen 2nd-quarter profit tops Street view, raises 2016 forecast
(Reuters) – Amgen (NSDQ:AMGN) on Wednesday reported higher-than-expected 2nd-quarter profit on increased sales of its blockbuster rheumatoid arthritis drug Enbrel and newer medicines, and the company again raised its full-year forecast. The forecast appeared to signal management’s confidence in the 2nd half of the year. The company is on track to meet or exceed its long-term objectives,” Chief Executive Robert Bradaway said in a statement. Amgen said it now expects 2016 adjusted earnings per share of $11.10 to $11.40, up from its prior view of $10.85 to $11.20. Its midpoint is above of Wall...
Source: Mass Device - July 27, 2016 Category: Medical Equipment Authors: MassDevice Tags: Business/Financial News Drug-Device Combinations Amgen Source Type: news

CHMP Backs Abatacept (Orencia) for MTX-Naive Patients With RA CHMP Backs Abatacept (Orencia) for MTX-Naive Patients With RA
The EMA's Committee for Medicinal Products for Human Use recommended marketing authorization for abatacept in combination with methotrexate for methotrexate-naive adults with rheumatoid arthritis. International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 26, 2016 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

Concordance With the ACR RA Treatment Recommendations Concordance With the ACR RA Treatment Recommendations
Which factors may influence the use of DMARDs in rheumatoid arthritis? Are treatment patterns consistent with the published recommendations? Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 26, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

NHS too slow helping people with inflammatory arthritis
The  NHS is failing to assess people with rheumatoid and early inflammatory arthritis quickly enough, a clinical audit has shown. Rheumatoid arthritis (and other forms of  early or inflammatory arthritis, or EIA)  are conditions in which the immune system attacks the joints, making them inflamed   & ndash; hot, red, painful and swollen. These conditions can lead to long term joint damage causing pain and disability. Urgent, intensive treatment is needed when these conditions occur to stop inflammation and prevent long-term damage. Published on 25 July 2016, the audit is now in its ...
Source: Arthritis Research UK - July 24, 2016 Category: Rheumatology Source Type: news

Experts criticise arthritis patient referral delays
Just a fifth of patients are referred by GPs quickly enough Related items from OnMedica 40% of European patients unlikely to access RA drugs Arthritis patients wait too long for referral RA risk lower after urinary and gut infections Drug for rheumatoid arthritis appears to have effect on severe eczema (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 24, 2016 Category: UK Health Source Type: news

"It's A Scandal" -Daryl Hall on Doctors Denying Chronic Lyme
Growing up a musically-obsessed child in the 80's, Daryl Hall was one of my biggest inspirations. A masterful, inventive songwriter with an ocean of soul, he set me on the path to being an artist, to never waste a word, and to sing because I mean it. With six number ones and five additional top ten hits throughout the 70's and 80's Daryl Hall and John Oates are the number one duo in music history. Still at the top of his game at 69 years old, Daryl has won legions of new fans with his hit MTV Live show Live From Daryl's House. In February of 2015, at my very sickest from chronic Lyme and Bartonella, after it was missed b...
Source: Science - The Huffington Post - July 22, 2016 Category: Science Source Type: news

A more powerful way to develop therapeutics?
Scientists have developed a new method for identifying the raw ingredients necessary to build'biologics,' a powerful class of medications that has revolutionized treatment of diseases like rheumatoid arthritis and some cancers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 21, 2016 Category: Science Source Type: news

A more powerful way to develop therapeutics?
( University of Toronto ) A University of Toronto scientist has developed a new method for identifying the raw ingredients necessary to build 'biologics,' a powerful class of medications that has revolutionized treatment of diseases like rheumatoid arthritis and some cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 21, 2016 Category: Cancer & Oncology Source Type: news

Bristol-Myers Squibb launches Orencia ClickJect drug-device combo for rheumatoid arthritis
Bristol-Myers Squibb said today it launched the Orencia ClickJect autoinjector designed for the self-administration of Orencia to treat moderate to severe rheumatoid arthritis. The Orencia ClickJect is designed to deliver 125 mg of subcutaneous Orencia through a push button operation with injection confirmation to reduce the possibility of user errors, the company said. “Today’s launch of the Orencia ClickJect is an example of our continued commitment to offering patients with moderate to severe rheumatoid arthritis a treatment option that may be appropriate for them, now available as an autoinjector....
Source: Mass Device - July 20, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Drug-Device Combinations Bristol-Myers Squibb Co. Source Type: news

Rheumatoid Arthritis vs. Osteoarthritis
Title: Rheumatoid Arthritis vs. OsteoarthritisCategory: Doctor's & Expert's views on SymptomsCreated: 7/19/2016 12:00:00 AMLast Editorial Review: 7/19/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 19, 2016 Category: Rheumatology Source Type: news

15 Early Symptoms and Signs of Rheumatoid Arthritis (RA)
Title: 15 Early Symptoms and Signs of Rheumatoid Arthritis (RA)Category: Diseases and ConditionsCreated: 6/24/2013 12:00:00 AMLast Editorial Review: 7/19/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 19, 2016 Category: Rheumatology Source Type: news

Samsung Bioepis seeks Europe approval for its Humira copy
SEOUL (Reuters) - Biosimilars maker Samsung Bioepis, part of South Korea's top family-run conglomerate Samsung Group [SAGR.UL], said on Monday it is seeking regulatory approval in Europe to sell its copy of AbbVie Inc's rheumatoid arthritis drug Humira. (Source: Reuters: Health)
Source: Reuters: Health - July 18, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Understanding Rheumatoid Arthritis Medications
Rheumatoid Arthritis Medications (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 14, 2016 Category: Journals (General) Source Type: news

Severe rheumatoid arthritis therapy receives provisional UK recommendation
A potentially beneficial new treatment for severe rheumatoid arthritis has been recommended for NHS use in draft guidance from the UK's leading healthcare regulator.The National Institute for Health and Care Excellence (NICE) has issued provisional guidelines that, if finalised, will mean thousands of people with severe forms rheumatoid arthritis will have a wider range of therapy options from which to choose.The new guidance The drug, certolizumab pegol, is also known under the brand name Cimzia and is already recommended by NICE for treating cases of severe rheumatoid arthritis that has not responded to intensive the...
Source: Arthritis Research UK - July 13, 2016 Category: Rheumatology Source Type: news

Summary of Evidence: Musculoskeletal Inflammation and Natural Products
Learn what the science says about musculoskeletal inflammation and natural products in the current issue of NCCIH Clinical Digest. Read more about the evidence base of tumeric, bromelain, willow bark, Omega-3 fatty acids, devil’s claw, ginger and thunder god vine in the treatment of conditions like osteoarthritis, rheumatoid arthritis, and tendinitis. /da (Source: MCR News)
Source: MCR News - July 13, 2016 Category: Databases & Libraries Authors: liaison Tags: All Members Source Type: news

Rheumatoid Arthritis (RA)
Title: Rheumatoid Arthritis (RA)Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 7/13/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 13, 2016 Category: Rheumatology Source Type: news

FDA: Novartis Arthritis Drug 'Highly Similar' to Amgen's Enbrel
The injection is used to treat five chronic inflammatory conditions, including rheumatoid arthritis and plaque psoriasis. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - July 12, 2016 Category: Pharmaceuticals Source Type: news

Nerve zap eased rheumatoid arthritis in small study
Amy Norton, HealthDay News Electronic stimulation of a nerve running from the brain to the gut may help ease stubborn symptoms of rheumatoid arthritis, preliminary research suggests. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 12, 2016 Category: Consumer Health News Source Type: news

Nerve Zap May Ease Rheumatoid Arthritis
Treatment worked some for patients who weren't responding to drugs (Source: WebMD Health)
Source: WebMD Health - July 12, 2016 Category: Consumer Health News Source Type: news

Nerve Zap Eased Rheumatoid Arthritis in Small Study
Treatment worked some for patients who weren't responding to drugs Source: HealthDay Related MedlinePlus Page: Rheumatoid Arthritis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 12, 2016 Category: Consumer Health News Source Type: news

Abatacept Monotherapy vs Abatacept Plus DMARDs in RAAbatacept Monotherapy vs Abatacept Plus DMARDs in RA
What benefits do the addition of DMARDs to abatacept therapy offer patients with rheumatoid arthritis? Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Nerve Zap Eased Rheumatoid Arthritis in Small Study
TUESDAY, July 12, 2016 -- Electronic stimulation of a nerve running from the brain to the gut may help ease stubborn symptoms of rheumatoid arthritis, preliminary research suggests. The study, of 17 adults with the painful autoimmune disease,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 12, 2016 Category: Journals (General) Source Type: news

Nerve Zap Eased Rheumatoid Arthritis in Small Study
Title: Nerve Zap Eased Rheumatoid Arthritis in Small StudyCategory: Health NewsCreated: 7/12/2016 12:00:00 AMLast Editorial Review: 7/12/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 12, 2016 Category: Rheumatology Source Type: news

Gut bacteria can cause, predict and prevent rheumatoid arthritis
The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests a new report. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 11, 2016 Category: Science Source Type: news

Make the Diagnosis: Mysterious Skin Patches
(MedPage Today) -- Case Findings: A 70-year-old man went to urgent care after becoming concerned about brown hyperpigmented patches on his legs and arms. He also thought that some of his teeth were turning gray, but it had been happening so slowly he wasn't sure. He had been in good health recently, especially after starting on antibiotics last year to treat his rheumatoid arthritis. What is your diagnosis? (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - July 11, 2016 Category: Dermatology Source Type: news

Nerve stimulation 'eases symptoms' of chronic condition rheumatoid arthritis
NERVE stimulation can reduce the symptoms of rheumatoid arthritis and could help people suffering from other inflammatory diseases, such as Crohns, Parkinson’s and Alzheimer’s (Source: Daily Express - Health)
Source: Daily Express - Health - July 11, 2016 Category: Consumer Health News Source Type: news

Study: Gut bacteria can cause, predict and prevent rheumatoid arthritis
(Mayo Clinic) The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests Veena Taneja, Ph.D., an immunologist at Mayo Clinic's Center for Individualized Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 11, 2016 Category: Global & Universal Source Type: news

Study: Gut Bacteria can Cause, Predict and Prevent Rheumatoid Arthritis
ROCHESTER, Minn. — The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests Veena Taneja, Ph.D., an immunologist at Mayo Clinic’s Center for Individualized Medicine. Dr. Taneja recently published two studies ─ one in Genome Medicine and one in Arthritis and Rheumatology ─ connecting the [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - July 10, 2016 Category: Hospital Management Source Type: news

Immunotherapy reduces cardiovascular risk in rheumatoid arthritis
Immunotherapy reduces cardiovascular risk in patients with rheumatoid arthritis, according to new research. The combination of two extra-low dose anticytokine drugs reduced rheumatoid arthritis disease activity and cardiovascular events. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 10, 2016 Category: Science Source Type: news

Immunotherapy reduces cardiovascular risk in rheumatoid arthritis
(European Society of Cardiology) Weight loss from bariatric surgery appears to reverse the premature aging associated with obesity, according to research presented today at Frontiers in CardioVascular Biology (FCVB) 2016.1 Patients had longer telomeres and less inflammation two years later. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 9, 2016 Category: Global & Universal Source Type: news

Blockbuster Hopes Grow for Ablynx Arthritis Drug Backed by AbbvieBlockbuster Hopes Grow for Ablynx Arthritis Drug Backed by Abbvie
Ablynx's hopes for a potential multibillion-dollar drug were boosted on Thursday by strong clinical trial results in rheumatoid arthritis, vindicating a $175 million bet placed on the product by U.S. pharma group AbbVie in 2013. Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - July 8, 2016 Category: Orthopaedics Tags: Rheumatology News Source Type: news

Rheumatoid arthritis pain 'linked with higher chance of fatigue'
This study is interesting as it indicates that younger people with rheumatoid arthritis and those with more pain also experience greater fatigue. It emphasises the need for better treatments and management techniques to deal with fatigue for those living with rheumatoid arthritis on a daily basis." (Source: Arthritis Research UK)
Source: Arthritis Research UK - July 7, 2016 Category: Rheumatology Source Type: news

Effect of cholesterol medicine on inflammatory diseases mapped
The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defense system with regard to diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis. Researchers have now explored why this is so, and their findings may result in improved treatment. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 7, 2016 Category: Science Source Type: news

Musculoskeletal Inflammation and Natural Products
Many natural products have purported anti-inflammatory properties, and some have a long history of use for treating inflammation and the pain that is associated with musculoskeletal inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and tendinitis. Although there is some limited evidence that a few natural products may provide modest benefits, in general, there is insufficient evidence to support the use of many of these natural products for inflammatory conditions. (Source: NCCAM Featured Content)
Source: NCCAM Featured Content - July 7, 2016 Category: Complementary Medicine Authors: NCCIH Source Type: news

Effect of cholesterol medicine on inflammatory diseases mapped
(Aarhus University) The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defence system with regard to diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis. Danish researchers have now explored why this is so, and their findings may result in improved treatment. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 7, 2016 Category: Biology Source Type: news