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Otezla Disappoints in RA (CME/CE)
(MedPage Today) -- Efficacy of apremilast in rheumatoid arthritis no different from placebo. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 25, 2015 Category: Primary Care Source Type: news

Allergies: Food Allergy Link to Forms of Arthritis
Arthritis is one of the most debilitating conditions in the United States of America. Arthritis is the number one cause of lost work days for employees of the Boeing Corporation, for example. Treatment is limited and almost entirely concentrated on anti-inflammatory medications, not on eliminating the original cause of the inflammation. The word, 'arthritis,' means, 'joint inflammation.' There are basically two forms of arthritis, osteoarthritis and rheumatoid arthritis. (Source: Disabled World)
Source: Disabled World - March 24, 2015 Category: Disability Tags: Food Allergy Source Type: news

The High Price of Affordable Medicine
In the old days, blockbuster drugs were moderately expensive pills taken by hundreds of thousands of patients. Think blood pressure, cholesterol and diabetes pills. But today, many blockbusters are designed to target much less common diseases, illnesses like multiple sclerosis and rheumatoid arthritis or even specific subcategories of cancer. These medications have become blockbusters not through the sheer volume of their sales, but as a result of their staggeringly high prices. Tens of thousands of dollars per patient, per year. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 24, 2015 Category: Pharmaceuticals Authors: Peter Ubel Source Type: news

Scientists Develop First Blood Test For Osteoarthritis
Researchers have isolated a biomarker that could indicate the early onset of both osteoarthritis (OA) and rheumatoid arthritis (RA). The discovery could be developed into a blood test to differentiate between the conditions before the onset of symptoms, which could improve patient outcomes. (Source: Medical Design Online News)
Source: Medical Design Online News - March 24, 2015 Category: Medical Equipment Source Type: news

Mayo Clinic Q and A: Genetic, environmental factors appear to play a role in risk for RA
DEAR MAYO CLINIC: My daughter, 31, was recently diagnosed with rheumatoid arthritis. Do doctors know what causes the disease, especially at a young age? Will she need to be on medication for the rest of her life? ANSWER: The precise cause of rheumatoid arthritis, or RA, remains unclear. However, both genetic and environmental factors appear [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 24, 2015 Category: Databases & Libraries Source Type: news

Blood test could provide an early arthritis warning
ConclusionThis laboratory study suggests that for people presenting with early joint symptoms, examining blood levels of a combination of proteins could help to distinguish people who have early-stage OA from those who have early-stage RA or other inflammatory arthritis.  However, this study is in the early stages and so far has only looked at relatively small samples of people with confirmed diagnoses of these different conditions. A lot of further work needs to be done to examine the accuracy of such a blood test, and to see whether it could reliably identify and distinguish between people with these conditions pres...
Source: NHS News Feed - March 23, 2015 Category: Consumer Health News Tags: Medical practice Older people Source Type: news

Rheumatoid arthritis pain: Tips for protecting your joints
(Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - March 21, 2015 Category: Consumer Health News Source Type: news

Researchers Explore Hepatitis B Reactivation in Patients With Rheumatoid Arthritis Treated With Both DMARD and Antiviral Therapy
Source: Lippincott’s Bone and Joint Newsletter - March 20, 2015 Category: Orthopaedics Tags: CME Article Source Type: news

'Ground Zero' Workers At Risk of Autoimmune Diseases
Prolonged exposure linked to rheumatoid arthritis, lupus Source: HealthDay Related MedlinePlus Pages: Autoimmune Diseases, Occupational Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 19, 2015 Category: Consumer Health News Source Type: news

Ablynx initiates the first of two Phase IIb RA studies with its anti-IL-6R nanobody, partnered with Abbvie
Ablynx announced that it has administered the first dose in the Phase IIb study to evaluate the efficacy and safety of its anti-IL-6R Nanobody®, ALX-0061, administered subcutaneously in combination with methotrexate (MTX) in adult patients with active RA, despite MTX therapy. The study aims to identify the optimum dose and frequency of administration of ALX-0061 for the next phases of development. (Source: Pharmacy Europe)
Source: Pharmacy Europe - March 19, 2015 Category: Drugs & Pharmacology Authors: Annabel De Coster Tags: *** Editor's Pick Clinical trials Practical therapeutics Industry News Drug development Rheumatology Patient care anti-IL-6R DMARD Latest News methotrexate nanobody rheumatoid arthritis Source Type: news

Breastfeeding for longer linked to higher IQ claim
Baby breastfed for at least a year gained four IQ points, claims study Related items from OnMedicaLonger breastfeeding improves child’s IQ later in lifeBreastfeeding can delay cancer onsetMoney for breastfeeding mothersBreastfeeding may halve rheumatoid arthritis riskBreastfeeding (Source: OnMedica Latest News)
Source: OnMedica Latest News - March 19, 2015 Category: UK Health Source Type: news

Drug treatment for rheumatoid arthritis. TACIT trial.
An NIHR HTA programme funded trial looking at drug treatments for rheumatoid arthritis has had its findings published in the British Medical Journal. (BMJ)Rheumatoid arthritis (RA) is a common condition causing pain through inflammation of the joints with progressive joint damage leading to disability.Tumour necrosis factor inhibitor (TNF) is an innovative biological new... (Source: NIHR Evaluation, Trials and Studies News)
Source: NIHR Evaluation, Trials and Studies News - March 17, 2015 Category: American Health Source Type: news

Autoimmune Disease Super-Regulators Uncovered
Genetic switches called super-enhancers help regulate the human immune system. The finding will inform research into autoimmune disorders such as rheumatoid arthritis. (Source: NIH Research Matters)
Source: NIH Research Matters - March 16, 2015 Category: Research Source Type: news

Spherical nucleic acids set stage for new paradigm in drug development
(Northwestern University) A Northwestern University-led research team led is the first to show spherical nucleic acids (SNAs) can be used as potent drugs to effectively train the immune system to fight disease, by either boosting or dampening the immune response. By increasing the immune response toward a specific cell type, SNAs could be used to target anything from influenza to different forms of cancer. If used to suppress the immune response, SNAs could target autoimmune disorders, such as rheumatoid arthritis and psoriasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 16, 2015 Category: Cancer & Oncology Source Type: news

Inflammation in mouth, joints in rheumatoid arthritis
Periodontitis shares pathogenic mechanisms with rheumatoid arthritis (RA) and may trigger its onset, scientists say. In a new study, researchers performed joint and dental examinations, determined Porphyromonas gingivalis (P. gingivalis) antibodies, and examined inflammatory microenvironments in early and chronic RA patients. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 12, 2015 Category: Science Source Type: news

Inflammation in the mouth and joints in rheumatoid arthritis
(International & American Associations for Dental Research) Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Sheila Arvikar, Massachusetts General Hospital, Boston, USA, will present a study titled 'Inflammation in the Mouth and Joints in Rheumatoid Arthritis.' The IADR General Session is being held in conjunction with the 44th Annual Meeting of the American Association for Dental Research and the 39th Annual Meeting of the Canadian Association for Dental Research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 12, 2015 Category: Global & Universal Source Type: news

Diagnosing rheumatoid arthritis: how it works
You should see your GP if you have these symptoms so they can try to determine the cause. (Source: Telegraph Health)
Source: Telegraph Health - March 11, 2015 Category: Consumer Health News Tags: rheumatoid arthritis diagnosed blood test Source Type: news

M-MDSCs shut down arthritis in mouse model of the disease
(Federation of American Societies for Experimental Biology) Using a mouse model of rheumatoid arthritis, scientists have discovered that a form of cellular immunotherapy by intravenous administration of monocytic myeloid-derived suppressor cells, or M-MDSCs, might be an effective treatment for the disease in humans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 6, 2015 Category: Global & Universal Source Type: news

Well: Think Like a Doctor: Thinner
Can you figure out what is wrong with a 58-year-old woman with bad arthritis who develops a terrible wasting illness after what looked like a simple cold? (Source: NYT)
Source: NYT - March 6, 2015 Category: American Health Authors: LISA SANDERS, M.D. Tags: Doctors Tuberculosis Rheumatoid Arthritis Tests and Examinations Weight Think Like a Doctor Lung Cancer Featured Source Type: news

Well: Think Like a Doctor: Thinner
Can you figure out what is wrong with a 58-year-old woman with bad arthritis who develops a terrible wasting illness after what looked like a simple cold? (Source: NYT Health)
Source: NYT Health - March 5, 2015 Category: Consumer Health News Authors: LISA SANDERS, M.D. Tags: Doctors Tuberculosis Rheumatoid Arthritis Tests and Examinations Weight Think Like a Doctor Lung Cancer Featured Source Type: news

Biosimilar Copies of Blockbuster Drug Launch in Major EU MarketsBiosimilar Copies of Blockbuster Drug Launch in Major EU Markets
Cheap versions of a top-selling drug for rheumatoid arthritis and Crohn's disease are being launched across major European markets in an important advance for biosimilar drugs. Reuters Health Information (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 26, 2015 Category: Drugs & Pharmacology Tags: Pharmacist News Source Type: news

FDA postpones key hearing on biosimilar copy of blockbuster drug
(Reuters) - The U.S. Food and Drug Administration has postponed a crucial meeting of an advisory committee to consider a cheap version of a top-selling drug for rheumatoid arthritis and Crohn's disease, which had been scheduled for March 17. (Source: Reuters: Health)
Source: Reuters: Health - February 26, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

How Do You Diagnose Hypermobility?
Discussion Hypermobility can be seen in several different clinical entities. These include generalized joint hypermobility, joint hypermobility syndrome, Marfan syndrome, Ehlers-Danlos syndrome and Osteogenesis Imperfecta. For adults, a Beighton score of at least 4 or 5 is used as a definition of hypermobility. For children a score of 5 or 6 is used as a definition. (see scoring system below). Generalized joint hypermobility is hypermobility with few or no symptoms. If they occur, knee symptoms are the most common. Joint hypermobility syndrome has hypermobility along with other symptoms such as pain, reduced muscle stren...
Source: PediatricEducation.org - February 23, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Tropical Virus Symptoms Can Mimic Rheumatoid Arthritis
Similarities may make diagnosis of chikungunya more difficult, researchers say Source: HealthDay Related MedlinePlus Pages: Rheumatoid Arthritis, Viral Infections (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 20, 2015 Category: Consumer Health News Source Type: news

How Early Is 'Early Enough' in the Treatment of RA?How Early Is 'Early Enough' in the Treatment of RA?
Dr Kevin Deane reviews and comments on a study evaluating the relationship between the timing of treatment initiation and 'cure' in patients with rheumatoid arthritis. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - February 20, 2015 Category: Rheumatology Tags: Rheumatology Viewpoint Source Type: news

Rheumatology Research Highlights - Winter 2015
(Wiley) Rheumatology Research Highlights provides members of the media with important medical evidence that focuses on rheumatic diseases such as rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, juvenile arthritis and fibromyalgia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2015 Category: Global & Universal Source Type: news

Your NEJM Group Today: Smoking & Mortality, Rheumatoid Arthritis & CV Risk, Boston Otolaryngology Opportunity (FREE)
By The Editors NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today:NEJM Clinical … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 18, 2015 Category: Primary Care Source Type: news

NIH researchers reveal link between powerful gene regulatory elements and autoimmune diseases
Investigators with the National Institutes of Health (NIH) have discovered the genomic switches of a blood cell are key to regulating the human immune system. The findings, published in Nature today, Feb. 17, 2015, open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. (Source: NHGRI Press Releases)
Source: NHGRI Press Releases - February 17, 2015 Category: Genetics & Stem Cells Source Type: news

Cardiovascular Risk in Rheumatoid ArthritisCardiovascular Risk in Rheumatoid Arthritis
How does inflammation influence lipid profiles and cardiac risk in RA patients? Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 17, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Evaluating Drug-free Remission With Abatacept in Early RAEvaluating Drug-free Remission With Abatacept in Early RA
Does the addition of abatacept to MTX therapy help achieve drug-free remission in early rheumatoid arthritis? Annals of the Rheumatic Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 17, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Link between powerful gene regulatory elements and autoimmune diseases
Investigators have discovered the genomic switches of a blood cell key to regulating the human immune system. The findings open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 16, 2015 Category: Science Source Type: news

Remodelling delivery of mAbs in rheumatoid arthritis
Tocilizumab, a monoclonal antibody targeted at the interleukin-6 receptor, is now available as a subcutaneous formulation for the management of moderate to severe rheumatoid arthritis (Source: Pharmacy Europe)
Source: Pharmacy Europe - February 16, 2015 Category: Drugs & Pharmacology Authors: ebercott Tags: Rheumatology Featured Articles Source Type: news

NIH researchers reveal link between powerful gene regulatory elements and autoimmune diseases
(NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases) Investigators with the National Institutes of Health have discovered the genomic switches of a blood cell key to regulating the human immune system. The findings, published in Nature today, open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 16, 2015 Category: Global & Universal Source Type: news

Four reasons your autoimmune disorder won't go away
(NaturalNews) Auto-immune disorders are crippling the people of this planet. Whether it's celiac, Graves, Hashimoto's, multiple sclerosis, rheumatoid arthritis, or lupus, these disorders cause considerable pain and destruction of all areas of the body. Although many sufferers have... (Source: NaturalNews.com)
Source: NaturalNews.com - February 14, 2015 Category: Consumer Health News Source Type: news

Cardiovascular Disease: The Risk Across Rheumatic DiseasesCardiovascular Disease: The Risk Across Rheumatic Diseases
Dr Deane reviews and comments on the results of a longitudinal cohort study evaluating cardiovascular disease risk among patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 6, 2015 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news

Certain Infections Linked to Reduced Risk of Rheumatoid Arthritis
Title: Certain Infections Linked to Reduced Risk of Rheumatoid ArthritisCategory: Health NewsCreated: 2/5/2015 12:00:00 AMLast Editorial Review: 2/6/2015 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 6, 2015 Category: Rheumatology Source Type: news

Certain Infections Linked to Reduced Risk of Rheumatoid Arthritis
Gut, urinary tract and genital conditions may offer some protection, study suggests (Source: WebMD Health)
Source: WebMD Health - February 5, 2015 Category: Consumer Health News Source Type: news

Certain Infections Linked to Reduced Risk of Rheumatoid Arthritis
Gut, urinary tract and genital conditions may offer some protection, study suggests Source: HealthDay Related MedlinePlus Pages: Bacterial Infections, Rheumatoid Arthritis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 5, 2015 Category: Consumer Health News Source Type: news

7 Things You Should Know About Autoimmune Diseases
As if living with chronic illness wasn't challenging enough, living with an autoimmune disease can be even more difficult. Still highly misunderstood by medical professionals and the public alike, autoimmune diseases are characterized by nebulous symptoms that can make diagnoses difficult to come by. Treatments vary, and in some cases rely entirely on behavior changes. In an effort to making living with -- or loving someone with -- an autoimmune disease just a little bit easier, here are seven important things to know about these health conditions. 1. Autoimmune diseases essentially cause a person's body to fight itself...
Source: Healthy Living - The Huffington Post - February 5, 2015 Category: Consumer Health News Source Type: news

Could Infections Protect Against RA? (CME/CE)
(MedPage Today) -- Risk of rheumatoid arthritis was lower with recent gastroenteritis. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 5, 2015 Category: Rheumatology Source Type: news

RA risk lower after urinary and gut infections
But respiratory infections have no effect on risk of developing the diseaseRelated items from OnMedicaBreastfeeding may halve rheumatoid arthritis riskArthritis patients wait too long for referral40% of European patients unlikely to access RA drugsNewer RA drugs no better than old in keeping patients at work (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 5, 2015 Category: UK Health Source Type: news

Well: Infections Tied to Lower Rheumatoid Arthritis Risk
Stomach and urinary tract infections are associated with a reduced risk for rheumatoid arthritis. (Source: NYT)
Source: NYT - February 4, 2015 Category: American Health Authors: By NICHOLAS BAKALAR Tags: Rheumatoid Arthritis Body Featured Source Type: news

Well: Infections Tied to Lower Rheumatoid Arthritis Risk
Stomach and urinary tract infections are associated with a reduced risk for rheumatoid arthritis. (Source: NYT Health)
Source: NYT Health - February 4, 2015 Category: Consumer Health News Authors: By NICHOLAS BAKALAR Tags: Rheumatoid Arthritis Body Featured Source Type: news

Well: Infections Tied to Lower Rheumatoid Arthritis Risk
Stomach and urinary tract infections are associated with a reduced risk for rheumatoid arthritis. (Source: NYT)
Source: NYT - February 4, 2015 Category: Nutrition Authors: By NICHOLAS BAKALAR Tags: Rheumatoid Arthritis Body Featured Source Type: news

Study: Heritability of RA Remains Unexplained (CME/CE)
(MedPage Today) -- Established risk factors only provide partial explanation for familial risk of rheumatoid arthritis. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - February 4, 2015 Category: Primary Care Source Type: news

Amgen's Phase III ABP 501 trial in rheumatoid arthritis patients meets endpoints
US-based biopharmaceutical firm Amgen has reported positive results from its Phase III trial of biosimilar candidate ABP 501 compared with Humira (adalimumab) in patients with moderate-to-severe rheumatoid arthritis. (Source: Drug Development Technology)
Source: Drug Development Technology - February 4, 2015 Category: Pharmaceuticals Source Type: news

Amgen Biosimilar Rheumatoid Arthritis Therapy Shows Positive Results
Amgen said its investigational biosimilar treatment for moderate-to-severe rheumatoid arthritis demonstrated clinical equivalence in safety and effectiveness with AbbVie’s Humira after 24 weeks in a phase III study. (Source: WSJ.com: Health)
Source: WSJ.com: Health - February 3, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

Stroke Rounds: Inflammation Markers Boost RA Risk (CME/CE)
(MedPage Today) -- C-reactive protein, ESR linked to stroke/CHD in rheumatoid arthritis patients. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 3, 2015 Category: Cardiology Source Type: news

The influence of physical function on the risk of falls among adults with rheumatoid arthritis - Marques WV, Cruz VA, Rego J, da Silva NA.
OBJECTIVES: Identify fall prevalence in the last 12 months among patients with rheumatoid arthritis (RA) and verify the influence of disease activity and physical function in the risk of falls. METHODS: 43 patients with RA participated in this stud... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 1, 2015 Category: Global & Universal Tags: Age: Elder Adults Source Type: news