Cardinal Health(TM) Nuclear and Precision Health Solutions Receives U.S. Food and Drug Administration Approval for New LYMPHOSEEK(R) Pediatric Indication
The new indication will provide accurate and precise lymph node identification in pediatric patients one month and older with melanoma, rhabdomyosarcoma or other types of solid tumors
DUBLIN, Ohio, June 10, 2021 -- (Healthcare Sales & Marketing Network)... Biopharmaceuticals, Radiology, Oncology, FDA Cardinal Health, LYMPHOSEEK, sentinel lymph node biopsies (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 10, 2021 Category: Pharmaceuticals Source Type: news
Autologous HER2 CAR T Cells Induce Rhabdomyosarcoma Remission Autologous HER2 CAR T Cells Induce Rhabdomyosarcoma Remission
Infusion of autologous HER2 CAR T cells after lymphodepleting chemotherapy induced remission in a child with metastatic rhabdomyosarcoma (RMS), researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 20, 2020 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Immunotherapy with CAR T cells results in exceptional patient recovery
(Baylor College of Medicine) In a clinical trial, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2020 Category: Cancer & Oncology Source Type: news
UCLA Mattel Children ’s Hospital helps kids trick-or-treat
Three-year-old Harmon Jones strutted in his “Black Panther” costume as he prowled the UCLA Mattel Children’s Hospital hallways and main lobby for treats. After watching a special magic show and playing some tunes led by music therapists, he wanted some Halloween candy.“My favorite part is the lollipops!” Harmon said. “I like to share them with my mommy and daddy!”For Heather and Shaw Jones, Harmon ’s parents, holidays bring some sense of the normal and community. Last summer, Harmon was diagnosed with rhabdomyosarcoma, a rare cancer that forms in soft tissue — specifically skeletal muscle tissue or someti...
Source: UCLA Newsroom: Health Sciences - November 1, 2019 Category: Universities & Medical Training Source Type: news
New Standard of Care in Rhabdomyosarcoma? New Standard of Care in Rhabdomyosarcoma?
Maintenance therapy boosted survival in pediatric patients with RMS, and at least in Europe, it will be the standard of care in trials going forward.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 18, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Texas dad diagnosed with cancer that has only been reported in 400 adults over the last 30 years
Antonio Martinez, of San Antonio, Texas, was diagnosed in June with rhabdomyosarcoma, a cancer in which tumors develop from muscle or fibrous tissue, and resists most treatments. (Source: the Mail online | Health)
Source: the Mail online | Health - July 8, 2019 Category: Consumer Health News Source Type: news
What Causes Facial Nerve Palsy?
Discussion
Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Fishing for cures: New zebrafish model identifies drugs that kill pediatric cancer cells
(Massachusetts General Hospital) A new immunodeficient zebrafish model developed by Massachusetts General Hospital investigators promises to be less expensive, easier to use and to improve personalized therapies for cancers and potentially other diseases. The ability of the model to visualize drug responses at single-cell resolution in live animals allowed the team to identify a promising new treatment for rhabdomyosarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 25, 2019 Category: Cancer & Oncology Source Type: news
Suspicious spots on the lungs do not behave like metastases of rhabdomyosarcoma
(Princess Máxima Center for Pediatric Oncology) Small spots on CT scans of the lungs of children with muscle cancer do not have an adverse effect on survival according to an international research team in the Journal for Clinical Oncology. This conclusion has direct consequences for the treatment of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 14, 2019 Category: International Medicine & Public Health Source Type: news
Muscle stem cells can drive cancer that arises in Duchenne muscular dystrophy
People with Duchenne muscular dystrophy (DMD) can develop an otherwise-rare muscle cancer, called rhabdomyosarcoma, due to the muscle cells' continuous work to rebuild the damaged tissue. However, little is known about how the cancer arises, hindering development of a treatment or test that could predict cancer risk. (Source: World Pharma News)
Source: World Pharma News - January 15, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
Muscle stem cells can drive cancer that arises in Duchenne muscular dystrophy
(Sanford Burnham Prebys Medical Discovery Institute) Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have demonstrated that muscle stem cells may give rise to rhabdomyosarcoma that occurs during DMD--and identified two genes linked to the tumor's growth. The research, performed using a mouse model of severe DMD, helps scientists better understand how rhabdomyosarcoma develops in DMD--and indicates that ongoing efforts to develop treatments that stimulate muscle stem cells should consider potential cancer risk. The study was published in Cell Reports on January 15, 2019. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood with an unmet clinical need for decades. A single oncogenic fusion gene is associated with treatment resistance and a 40 to 45% decrease in overall survival. We previously showed that expression of this PAX3:FOXO1 fusion oncogene in alveolar RMS (aRMS) mediates tolerance to chemotherapy and radiotherapy and that the class I–specific histone deacetylase (HDAC) inhibitor entinostat reduces PAX3:FOXO1 protein abundance. Here, we established the antitumor efficacy of entinostat with chemotherapy in various preclinical cell and mouse models and fou...
Source: Signal Transduction Knowledge Environment - November 20, 2018 Category: Science Authors: Bharathy, N., Berlow, N. E., Wang, E., Abraham, J., Settelmeyer, T. P., Hooper, J. E., Svalina, M. N., Ishikawa, Y., Zientek, K., Bajwa, Z., Goros, M. W., Hernandez, B. S., Wolff, J. E., Rudek, M. A., Xu, L., Anders, N. M., Pal, R., Harrold, A. P., Davies Tags: STKE Research Articles Source Type: news
UA targeting rhabdomyosarcoma, a rare pediatric cancer with few treatment options
(University of Arizona Health Sciences) UA Cancer Center researcher harnesses 'big data' to identify targeted treatments for rhabdomyosarcoma, a rare cancer that mostly strikes children and teenagers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 31, 2018 Category: International Medicine & Public Health Source Type: news
I was 14 when I was told I had cancer. It inspired me to pursue my dream | Lucy Speechley
It was devastating at the time, but I met amazing people who helped me pursue a career in medical scienceI was 14 years old when I was told I had cancer. It was just before Christmas in 2009 and I ’d had terrible pain in my side for several weeks. After being seen at four different hospitals, I ended up at Birmingham children’s hospital. It was there that I was told I had alveolar rhabdomyosarcoma, words that meant absolutely nothing to me at first. I soon realised they meant cancer.Before my diagnosis, I was far more concerned with schoolwork and my friends – normal things 14-year-olds have to deal with. But my worl...
Source: Guardian Unlimited Science - September 20, 2018 Category: Science Authors: Lucy Speechley Tags: Society Health Cancer Cancer research Medical research Science Careers Education Students Higher education Children NHS Source Type: news
Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor
(St. Jude Children's Research Hospital) Research from the St. Jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project has revealed new vulnerabilities and leads for treatment of rhabdomyosarcoma (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 23, 2018 Category: Cancer & Oncology Source Type: news
