New research implicates immune system in Rett syndrome
The immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting children, new research suggests. Rett syndrome is a neurodevelopmental disorder that is caused primarily by mutations in the gene encoding for MeCP2, an important epigenetic regulator. Children with the disorder appear to develop normally but begin to lose acquired cognitive and motor skills at 6 to 18 months of age as symptoms start to show. As they age, patients are unable to acquire verbal skills and suffer from lack of motor control. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 11, 2015 Category: Science Source Type: news
New research implicates immune system in Rett syndrome
(University of Massachusetts Medical School) New research by investigators at the University of Massachusetts Medical School suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting children. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 11, 2015 Category: Biology Source Type: news
A biomarker for Rett syndrome: Measuring hand movements
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By Alice McCarthy
Boston Children's HospitalNews Well, Vector Blog, Big Data, Blogread more (Source: Mass Device)
Source: Mass Device - April 29, 2015 Category: Medical Equipment Authors: MassDevice Tags: Vector Blog Source Type: news
Surprising contributor to Rett syndrome identified
The immune system is designed to protect us from disease. But what if it was malfunctioning? Would it make a disease worse? That appears to be the case with Rett syndrome, a neurodevelopmental disorder, and possibly in other neurological disorders as well. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 21, 2015 Category: Science Source Type: news
Surprising contributor to Rett syndrome identified
(University of Virginia Health System) The immune system is designed to protect us from disease. But what if it was malfunctioning? Would it make a disease worse? That appears to be the case with Rett syndrome, a neurodevelopmental disorder, and possibly in other neurological disorders as well. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 21, 2015 Category: Global & Universal Source Type: news
Rett Syndrome Research Trust awards $1.3 million for clinical trial
(Case Western Reserve University) A surgical sedative may hold the key to reversing the devastating symptoms of a neurodevelopmental disorder found almost exclusively in females. Ketamine, used primarily for operative procedures, has shown such promise in mouse models that Case Western Reserve and Cleveland Clinic researchers soon will launch a two-year clinical trial using low doses of the medication in up to 35 individuals with Rett Syndrome. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2015 Category: Global & Universal Source Type: news
Rettsyndrome.org announces new 2014 grants, investing over $3.1M to accellerate research
(International Rett Syndrome Foundation) The International Rett Syndrome Foundation - now doing business as Rettsyndrome.org - announces today that twelve new grants were added to their research portfolio for a $1.2M investment, bringing the total 2014 research spend over $3.1M. Rettsyndrome.org is the leading private funder of Rett research, with more than $35 million invested to date. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 23, 2014 Category: Global & Universal Source Type: news
NIH's ORDR-NCATS RDCRN & NICHD awards U54 cooperative agreement for natural history study
(International Rett Syndrome Foundation) National Institute of Health announced awards to expand the Office of Rare Diseases Research part of the National Center for Advancing Translational Sciences collaborative Rare Diseases Clinical Research Network. Through the network, physician scientists at 22 consortia will work with 98 patient advocacy groups to advance clinical research and investigate new treatments for patients with rare diseases. The collaborations are made possible by $29 million in fiscal 2014 funding from NIH. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 28, 2014 Category: Global & Universal Source Type: news
Mouse Version of an Autism Spectrum Disorder Improves When Diet Includes a Synthetic Oil - 10/9/14
When young mice with the rodent equivalent of a rare autism spectrum disorder (ASD), called Rett syndrome, were fed a diet supplemented with the synthetic oil triheptanoin, they lived longer than mice on regular diets. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - October 9, 2014 Category: Research Source Type: news
Mouse version of an autism spectrum disorder improves when diet includes a synthetic oil
(Johns Hopkins Medicine) When young mice with the rodent equivalent of a rare autism spectrum disorder, called Rett syndrome, were fed a diet supplemented with the synthetic oil triheptanoin, they lived longer than mice on regular diets. Importantly, their physical and behavioral symptoms were also less severe after being on the diet, according to results of new research from The Johns Hopkins University. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 9, 2014 Category: Global & Universal Source Type: news
Blue Sky Day: Reaching for the stars with Rett syndrome
By Melinda Lancaster
Every mountaintop is within reach if you just keep climbing. —Barry Finlay (award-winning author and mountain climber)
On October 11, families and researchers will join together at the steps of Gordon Hall, on the campus of Harvard Medical School, to bring awareness to the struggle of our children with Rett syndrome. As our Blue Sky Girls (and one boy) begin their symbolic climb up the stairs, we are reminded of the effort researchers, parents, caregivers and especially the children themselves make on a daily basis to go onward and upward toward a goal once thought unreachable.
Rett syndrome is a d...
Source: Thrive, Children's Hospital Boston - September 30, 2014 Category: Pediatrics Authors: Guest Blogger Tags: All posts rett syndrome Source Type: news
Rett Syndrome: The incurable silent killer
EMMA Wellesley describes life with her daughter Skye who has an incurable genetic condition. (Source: Daily Express - Health)
Source: Daily Express - Health - August 25, 2014 Category: Consumer Health News Source Type: news
Rettsyndrome.org invests $1.5M in new 2014 awards
(International Rett Syndrome Foundation) The International Rett Syndrome Foundation now doing business as Rettsyndrome.org announces today that the Board of Trustees has awarded $1.5M to support 10 new grants to further translational research and launch of the neuro-habilitation therapeutic program, and fund clinical research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 18, 2014 Category: Global & Universal Source Type: news
Autism Spectrum Disorders (Pervasive Developmen...
Autism Spectrum Disorders (ASD), also known as Pervasive Developmental Disorders (PDDs), cause severe and pervasive impairment in thinking, feeling, language, and the ability to relate to others. These disorders are usually first diagnosed in early childhood and range from a severe form, called autistic disorder, through pervasive development disorder not otherwise specified (PDD-NOS), to a much milder form, Asperger syndrome. They also include two rare disorders, Rett syndrome and childhood disintegrative disorder. (Source: About.com Mental Health)
Source: About.com Mental Health - August 15, 2014 Category: Psychiatry Tags: health Source Type: news
Rett Syndrome Association of MA joins Rettsyndrome.org to explore treatment option
(International Rett Syndrome Foundation) Rett Syndrome Association of Massachusetts and Rettsyndrome.org are thrilled to announce today their renewed commitment to work together to defeat Rett syndrome. A generous $150,000 donation from RSAM will support a Rettsyndrome.org approved grant to Dr. Michela Fagiolini's project at the Boston Children's Hospital: 'Assessing NMDA receptor (NMDAr) modulators to ameliorate cortical regression in Rett syndrome'. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 6, 2014 Category: Global & Universal Source Type: news
