Clinical and laboratory profile of Expanded Dengue Syndrome: experience of 2019 outbreak from Dhaka, Bangladesh
CONCLUSION: In the year 2019, an unusual rise in EDS cases with about 15.4% fatalities were observed in this study. Hepatitis was the most common presentation and cause of death. Here, we report the first ARDS case encountered in Bangladesh. Despite the multifaceted presentation of EDS, indiscriminate use of antibiotics and steroid was minimal. Early recognition of multifarious features of EDS is important for choosing the targeted treatment option which can avert many deaths. The results of this study underline the necessity for more in-depth research into the risk factors that are contributing to mortality in EDS cases.P...
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Zazeba Hossain Forhad U Chowdhury Mohammad A Bari Sudip R Deb Ujjwal Mallik Sakib Aman Mohammad A Haque Syeda S Ahmed Waild Mohammad Afsan Bulbul Md Arman Hossain Murada Alam Muhammad K Islam Umma Salma Md Mujibur Rahman Fazle R Chowdhury Source Type: research

Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study
CONCLUSIONS: Exhaled metabolites analysis might enable asthma control classification in children. This should stimulate further development of exhaled metabolites-based point-of-care tests in asthma.PMID:38648186 | DOI:10.1164/rccm.202312-2270OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 22, 2024 Category: Respiratory Medicine Authors: Shahriyar Shahbazi Khamas Yoni Van Dijk Mahmoud I Abdel-Aziz Anne H Neerincx Jelle Blankestijn Susanne J H Vijverberg Simone Hashimoto Andrew Bush Aletta D Kraneveld Anna M Hedman Antoaneta A Toncheva Catarina Almqvist Christine Wolff Clare S Murray Gunil Source Type: research

Another Step Closer to Genomic-informed Therapeutic Dosing for Tuberculosis Drugs
Am J Respir Crit Care Med. 2024 Apr 22. doi: 10.1164/rccm.202403-0566ED. Online ahead of print.NO ABSTRACTPMID:38648185 | DOI:10.1164/rccm.202403-0566ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 22, 2024 Category: Respiratory Medicine Authors: Paul K Drain Source Type: research

A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing
CONCLUSION: Targeted sequencing can enable detection of polymorphisms influencing TB drug metabolism on a low-cost, portable instrument to personalize dosing for TB treatment or prevention. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).PMID:38647526 | DOI:10.1164/rccm.202309-1583OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 22, 2024 Category: Respiratory Medicine Authors: Renu Verma Kesia Esther da Silva Neesha Rockwood Roeland E Wasmann Nombuso Yende Taeksun Song Eugene Kim Paolo Denti Robert J Wilkinson Jason R Andrews Source Type: research

Sarcoid-Like Reactions to Immune Checkpoint Inhibitors: Incidence, Treatment Course, and Impact on Cancer Progression and Survival
CONCLUSIONS: SLRs are a known but understudied complication associated with ICI therapy. Multisystem SLR patients were more symptomatic and required ICI discontinuation and immune suppression. Larger studies are needed to fully evaluate the impact of SLR on cancer outcomes.PMID:38648910 | DOI:10.1016/j.rmed.2024.107640 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Hannah Smith Robert Easterling Jianing Ma Meghana Moodabagil Alexa Meara Dwight H Owen Elliot Crouser Arindam Singha Kevin Ho Source Type: research

In-Person Versus Remote 6-Minute Walk and Incremental Shuttle Walk Distances in Advanced Lung Disease
CONCLUSIONS: Differences in the distance walked may have resulted from different track lengths, widths, and walking surfaces. This should be considered in test interpretation if tests are repeated under different conditions.PMID:38649272 | DOI:10.4187/respcare.11417 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Lisa M Wickerson Manoela de Paula Ferreira Dmitry Rozenberg Sunita Mathur Lianne G Singer Source Type: research

Noninvasive Respiratory Support in Pediatric Critical Asthma: What to Start and Where to Go?
Respir Care. 2024 Apr 22;69(5):629-631. doi: 10.4187/respcare.12008.NO ABSTRACTPMID:38649273 | DOI:10.4187/respcare.12008 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Andrew Chevalier Kenzie Kennedy David Clegg Benjamin R White Source Type: research

Factors Associated With Time to Decannulation in Patients With Tracheostomy Following Severe Traumatic Brain Injury
CONCLUSIONS: This study found that a change in swallowing ability is a potentially significant factor for reducing time to decannulation. Identifying factors that could explain differences in time to decannulation is essential for patient outcomes, especially if these factors are modifiable and could be targeted in rehabilitation and treatment.PMID:38649274 | DOI:10.4187/respcare.11376 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Signe J Eskildsen Carrinna A Hansen Thomas Kallemose Derek J Curtis Irene Wessel Ingrid Poulsen Source Type: research

A Step Forward to Help Patients With COPD to Perform Ambulatory Exercises
Respir Care. 2024 Apr 22;69(5):627-628. doi: 10.4187/respcare.11956.NO ABSTRACTPMID:38649275 | DOI:10.4187/respcare.11956 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Jean-Luc Diehl Emmanuelle Gu érin Emmanuel Gu érot Source Type: research

Editor's Commentary
Respir Care. 2024 Apr 22;69(5):i.NO ABSTRACTPMID:38649276 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Source Type: research

Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study
CONCLUSIONS: Exhaled metabolites analysis might enable asthma control classification in children. This should stimulate further development of exhaled metabolites-based point-of-care tests in asthma.PMID:38648186 | DOI:10.1164/rccm.202312-2270OC (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Shahriyar Shahbazi Khamas Yoni Van Dijk Mahmoud I Abdel-Aziz Anne H Neerincx Jelle Blankestijn Susanne J H Vijverberg Simone Hashimoto Andrew Bush Aletta D Kraneveld Anna M Hedman Antoaneta A Toncheva Catarina Almqvist Christine Wolff Clare S Murray Gunil Source Type: research

Another Step Closer to Genomic-informed Therapeutic Dosing for Tuberculosis Drugs
Am J Respir Crit Care Med. 2024 Apr 22. doi: 10.1164/rccm.202403-0566ED. Online ahead of print.NO ABSTRACTPMID:38648185 | DOI:10.1164/rccm.202403-0566ED (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Paul K Drain Source Type: research

Relationship between obstructive sleep apnea and pulmonary hypertension: past, present and future
Expert Rev Respir Med. 2024 Apr 22. doi: 10.1080/17476348.2024.2345684. Online ahead of print.ABSTRACTINTRODUCTION: Obstructive sleep apnea (OSA) is a widely prevalent condition with consequent multiple organ systems complications. There is consensus that OSA is associated with negative effects on pulmonary hemodynamics but whether it contributes to development of clinical pulmonary hypertension (PH) is unclear.AREAS COVERED: In this review we 1) highlight previous studies looking into the possible bidirectional association of OSA and PH, focusing on those that explore clinical prognostic implications, 2) explore potential...
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Jyotirmayee Lenka Raymond Foley Mark Metersky Adrian Salmon Source Type: research

A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing
CONCLUSION: Targeted sequencing can enable detection of polymorphisms influencing TB drug metabolism on a low-cost, portable instrument to personalize dosing for TB treatment or prevention. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).PMID:38647526 | DOI:10.1164/rccm.202309-1583OC (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Renu Verma Kesia Esther da Silva Neesha Rockwood Roeland E Wasmann Nombuso Yende Taeksun Song Eugene Kim Paolo Denti Robert J Wilkinson Jason R Andrews Source Type: research

Impact of the coronavirus disease 2019 pandemic on the incidence of other infectious diseases in the hematology hospital in Korea
CONCLUSIONS: The implementation of COVID-19 infection control measures reduced the incidence of cRV infection. However, CDI increased significantly and incidence rates of CPE and VRE remained unchanged in hematological patients after the pandemic. Infection control measures suitable for each type of HCAI, such as stringent hand washing for CDI and enough isolation capacities, should be implemented and maintained in future pandemics, especially in immunocompromised patients.PMID:38649159 | DOI:10.3904/kjim.2023.508 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 22, 2024 Category: Internal Medicine Authors: Seohee Oh Yu-Sun Sung Mihee Jang Yong-Jin Kim Hyun-Wook Park Dukhee Nho Dong-Gun Lee Hyeon Woo Yim Sung-Yeon Cho Source Type: research