Golden Years, Digital Gears: Digital Health For Aging Populations
The elderly are not the archetypal target group of various digital health developments. We have already discussed the topic multiple times, however, nothing captures the main setbacks as accurately as this brilliant, and in my opinion, underrated sketch from Saturday Night Live. It’s a timeless piece, all tiny details – the characters, the device design, the voiceovers – nuggets of gold. Although features like continuous aFib screening (or blood pressure monitoring, alerts about changes in respiratory patterns, in gait, reminders on medication or drinking enough, and so on, and so on) would do more f...
Source: The Medical Futurist - November 21, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF health tech senior health AI digital health wearables Source Type: blogs

Fight Aging! Newsletter, November 20th 2023
In this study, we attempted to further explain the role, exact mechanism and target of ICA in treating AD from the ferroptosis perspective. We found that ICA could improve the neurobehavioral, memory, and motor abilities of AD mice. It could lower the ferroptosis level and enhance the resistance to oxidative stress. After inhibition of MDM2, ICA could no longer improve the cognitive ability of AD mice, nor could it further inhibit ferroptosis. Network pharmacological analysis revealed that MDM2 might be the target of ICA action. « Back to Top Particulate Air Pollution and Its Effects on the Mechan...
Source: Fight Aging! - November 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Path to Increasing Glutathione Levels in Mitochondria
Glutathione is an interesting cellular antioxidant, as increased levels can improve health in humans and slow aging in animal models. You might recall recent small human trials of high dose supplementation of glutathione precursors in order to achieve upregulation of glutathione, and corresponding studies in mice. It is thought that glutathione upregulation may largely improve health via mitochondrial function, as mitochondria are a prominent source of oxidative stress in aging cells. Here, researchers find a mechanism that regulates the amount of glutathione that enters the mitochondria, and thus a possible target to incr...
Source: Fight Aging! - November 15, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Breathalyzers, Breathomics And Exhalomics In The Digital Health Age
Most of us might take the breathing process for granted; after all it is an autonomous process that we only really start noticing when something about it is off. However, respiratory diseases are among the major causes of fatalities worldwide. The WHO estimates that by 2030, such conditions will be responsible for one in five deaths. As the signs of declining respiratory health or factors that influence it can be subtle, an array of digital health technologies and approaches have come to address such issues. Along with those innovations, new terminologies such as smart breathalyzers, breathomics and exhalome have entere...
Source: The Medical Futurist - October 24, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Health Sensors & Trackers Portable Medical Diagnostics breathalyzer breathomics exhalomics Source Type: blogs

VT? Or Supraventricular tachycardic rhythm with aberrancy?
A 70 something male presented in severe respiratory distress.The patient had altered mental status and so he was prepared for intubation.  Before intubation, he became  hypotensive.On the monitor patient had wide-complex tachycardia. The following 12-lead was obtained:What do you think?Differential is ventricular tachycardia versus supraventricular tachycardia with aberrancy versus sinus tachycardia with a aberrancy.  There are possible P waves in lead II. But these could be an extension of the QRS, so sinus tach is not certain.  Certainty could come with the use of Lewis leads. Much easi...
Source: Dr. Smith's ECG Blog - October 21, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Digital Health Anxiety: When Wellness Tech Becomes A Stressor
In today’s hyper-connected world, technology promises us a clearer insight into our health and well-being. With a glance at our wrist or a quick tap on our phones, we can get a snapshot of our heart rate, the quality of our sleep, or the number of steps we’ve taken in a day. These tools, designed to empower us, can sometimes have an unintended consequence: they can become sources of anxiety and stress. Lacing up your running shoes, you head out for a morning run. Looking forward to feeling the wind in your hair, the sun on your face, to enjoying the time to connect with nature and yourself. But the real-time...
Source: The Medical Futurist - October 19, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF digital health anxiety smartwatch wearables Source Type: blogs

Claira Sohn Cultivates Neurons and Diversity in the STEM Community
Credit: Courtesy of Claira Sohn. Claira Sohn credits her grandfather with sparking her interest in science. Although he never studied science at a 4-year university due to financial limitations, he took many community college classes and worked in chemistry labs developing products such as hair dyes and dissolvable stitches. “Every morning, my grandfather would take me to school, and we’d stop to get orange juice and a cookie and talk about science. When I was in elementary school, he bought me a book about quantum mechanics written for kids,” she says. “He inspired me to ask questions and encouraged me to go to ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - October 4, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Diseases Profiles Training Source Type: blogs

Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Chest discomfort and a dilated right ventricle. What's going on?
Written by Magnus Nossen MD, peer reviewed and edits by Smith, Meyers, GrauerA 60 something previously healthy female smoker sought medical attention after 2-3 days of intermittent chest discomfort. The chest discomfort was described as sharp. Episodes lasting 5-30 minutes. On the day of presentation she experienced another episode of chest discomfort accompanied by vomiting and throat pain. She was concerned about possible throat infection. She contacted her primary care physician. Due to the vague nature of her symptoms and the fact that she had chest discomfort and no clinical sign of throat infection she was referred f...
Source: Dr. Smith's ECG Blog - September 17, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs

Mitochondrial Epigenetics in Age-Related Mitochondrial Dysfunction
The hundreds of mitochondria present in every cell in the body undertake the essential duty of producing chemical energy store molecules, adenosine triphosphate (ATP), used to power the cell. With age, mitochondria become less efficient and more damaged, generating oxidative stress and triggering inflammation while producing less ATP than is optimal. This is thought to be a major contribution to degenerative aging, though as for all contributions to aging, it requires a highly targeted way to improve mitochondrial function in order to determine just how important it is. That highly targeted therapy doesn't yet exist in a u...
Source: Fight Aging! - September 15, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Device for Rapid COVID-19 Breath Testing
Researchers at Washington University School of Medicine have developed a COVID-19 breathalyzer test. The technology requires someone to breathe into it just once or twice, and it can then provide an indication if the person is infected with SARS-CoV-2 in as little as one minute. The device could be very useful fo screening large numbers of people prior to access to an indoor event, for instance, or in community clinics to quickly determine if people are infected. Moreover, the technology could be adapted to detect other viruses, which may be useful for future outbreaks. The system involves blowing into a straw, which direc...
Source: Medgadget - September 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Public Health wustl WUSTLmed Source Type: blogs

Cardiolipin Oxidation in Mitochondrial Dysfunction
An interesting question is posed here by some of the researchers responsible for creating plastoquinone mitochondrially-targeted antioxidants. To what degree do mitochondrially-targeted antioxidants improve mitochondrial function and modestly slow aging by preventing cardiolipin oxidation? Past a certain level of detail, less is known of mitochondrial biochemistry than one might think. This organelle is very well studied, but it is still the case that many approaches known to improve mitochondrial function are incompletely understood, or only understood in outline. It is clear that the mitochondrial generation of reactive ...
Source: Fight Aging! - September 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features – August 27, 2023 – Trilliant Health Opens its National Provider Directory for the First Time Ever, 60% of Patients Trust Independent Practices over Corporate Healthcare, and More
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News Levita received FDA clearance for its new product, the MARS™ platform. MARS expands on the Levita Magnetic Surgical System, to create a first-of-its-kind minimally invasive surgical platform aimed at the abdominal surger...
Source: EMR and HIPAA - August 27, 2023 Category: Information Technology Authors: Grayson Miller Tags: Healthcare IT AstraZeneca Carefeed Carium Cerner Community Health Network Danyele Homer Dignity Health Global Education DUOS eClinicalWorks Eliciting Insights Entira Family Clinics Fast Company Filecoin Health-Alert (Canada) Source Type: blogs

Up Your Game With NIH Kahoot! Quizzes
NIH is now a premium partner with Kahoot! Credit: NIGMS. We’re excited to announce our new partnership with Kahoot! Although we aren’t new Kahoot! gamers, we’ve recently partnered with them to provide you quizzes from across the National Institutes of Health (NIH) in a single place. “Reaching young people to teach them about biomedical science and inspire them to pursue careers in science is critically important to ensuring a diverse and vibrant biomedical research enterprise,” says NIGMS Director Jon Lorsch, Ph.D. “Our partnership with Kahoot! expands NIH’s STEM offerings, providing educators with free, in...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 23, 2023 Category: Research Authors: Chrissa Chverchko Tags: STEM Education Source Type: blogs