17-gene signature linked to remission after triple-negative breast cancer treatment
Mayo Clinic researchers have discovered a distinctive pattern in a specific set of 17 genes that may be associated with remission after treatment for triple-negative breast cancer. The multi-omics study, published in Breast Cancer Research, highlights the potential for further investigating this signature as a target for individualized medicine. Approximately 10-15% of breast cancers fall into the category of "triple-negative," indicating that their growth is not driven through the hormone receptors for estrogen or progesterone, nor by… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 21, 2023 Category: Research Source Type: news
Sleeping less than five hours a night can raise depression risk, study suggests
Consistently short sleep duration more likely to precede symptoms than inverse, genetic data revealSleeping less than five hours a night could raise the risk of developing symptoms of depression, research suggests.The link between poor sleep and mental ill health is well known, but it has been unclear which problem tends to come first. Now scientists have found evidence that consistent short sleep at night can be a precursor to developing depressive symptoms.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 20, 2023 Category: Science Authors: Hannah Devlin Science Correspondent Tags: Depression UK news Sleep Mental health Medical research Genetics & wellbeing Source Type: news
Mayo Clinic selects Owen Garrick, M.D., as dean of Clinical Trials
Mayo Clinic Research leaders are excited to announce the arrival of Owen Garrick, M.D., as the dean of Clinical Trials. Dr. Garrick will start in his new position on Oct. 30. The dean of Clinical Trials is tasked with strengthening Mayo Clinic's standing as a national leader of innovative, demand-generating clinical trials for patients everywhere. Dr. Garrick will lead the transformation of Mayo Clinic ’s clinical trials, including developing digital capabilities, accelerating the volume of remote… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 20, 2023 Category: Research Source Type: news
Eating red meat twice a week may increase type 2 diabetes risk, study finds
Experts claim latest research from Harvard University adds a greater level of certainty about the linkThe chances of a person developing type 2 diabetes can increase even if they eat red meat just two times a week instead of an alternative option, researchers have said.Replacing red meat with plant-based protein sources, such as nuts and legumes, may reduce the chances of developing the condition and would also help reduce greenhouse gas emissions and tackle climate change, according to experts at Harvard University.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 19, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Medical research Diabetes Meat Harvard University Source Type: news
Mayo Clinic and Oxford Nanopore announce collaboration to advance precision medicine for cancer and genetic disorders
Joint development collaboration to bring leading-edge nanopore sequencing into clinical laboratories at Mayo Clinic to increase understanding and improve treatment of cancer and genetic disorders ROCHESTER, Minn., and OXFORD, UK — Mayo Clinic and Oxford Nanopore Technologies, the company delivering a new generation of nanopore-based molecular sensing technology, today unveiled a multi-year joint development collaboration to develop new clinical tests for diseases and improve patient care. Mayo Clinic and Oxford Nanopore h ave identified several areas… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 19, 2023 Category: Research Source Type: news
People diagnosed with ADHD as adults could be ‘at greater risk of dementia’
Study does not establish cause and effect, and experts say it highlights need for further researchPeople who are diagnosed with attention deficit hyperactivity disorder (ADHD) as adults could be at greater risk of developing dementia later in life, research suggests.While experts cautioned that the study did not establish whether the apparent link was cause and effect, they say it highlights the need to explore possible connections further and examine whether ADHD medications mitigate any potential dementia risk.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 17, 2023 Category: Science Authors: Nicola Davis Science correspondent Tags: Attention deficit hyperactivity disorder Medical research Health Science Source Type: news
Half a million of us want to donate our data to British science, but it ’s languishing unused because of privacy fears | Polly Toynbee
Data supplied to UK Biobank is not for sale, it ’s not for trivial or suspect use, it’s for the good of humankind – and yet I had to jump through hoops to offer itI delight in messages fromUK Biobank, making me feel useful for minimal effort. Back in 2006, with half a million others aged between 40 and 69, I signed up to this magnificent project, the world ’s most advanced genetic database.They took blood, saliva and urine, measured bone density and made notes on exercise, alcohol and family history, with social class, ethnicity, education, employment and income included. They have sequenced my genome and stored sa...
Source: Guardian Unlimited Science - October 17, 2023 Category: Science Authors: Polly Toynbee Tags: Medical research NHS Health Data protection Science Society Technology UK news Source Type: news
Mayo Clinic Proceedings, Kidney International publish consensus statement on new approach to identifying kidney disorder
Forty-eight international experts on membranous nephropathy have co-authored a consensus report that calls for a new method of classifying diagnoses of the syndrome. They say the change would result in greater accuracy in diagnoses, which would open the door to improved patient care and targeted treatment. To call attention to the report, Mayo Clinic Proceedings and Kidney International have published the report simultaneously. Membranous nephropathy is a kidney disorder that involves immunologic attack on structures… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 17, 2023 Category: Research Source Type: news
New prostate cancer treatment may be ‘on the horizon’, say scientists
Ability to reverse cancer ’s resistance to therapy opens possibility of treatment for late-diagnosed menScientists say a new way to treat prostate cancer may be on the horizon after finding it is possible to reverse its resistance to therapy.More than a million men worldwide are diagnosed with the disease each year. The chances of survival are generally good, particularly if it is diagnosed early. Many can live for decades without symptoms or needing treatment.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 16, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Prostate cancer Men Cancer research Society Health Medical research UK news Science Source Type: news
Should I worry about my clicking joints – and stop cracking my knuckles?
Our knees, shoulders, necks and hands make all sorts of pops and clicks. Sometimes we even encourage them. But is this the sound of damage being done?When Donald Unger was a child, his mother and several aunts – and later his mother-in-law – told him that cracking his knuckles would lead to arthritis. Rather than stop (or at least do it less obtrusively), Unger embarked on his own experimental programme: for 50 years, he cracked the knuckles of his left hand at least twice a day, leaving his right-han d knuckles to crack spontaneously, or not at all. After 36,500 cracks or so, the results were clear, at least for Unger...
Source: Guardian Unlimited Science - October 15, 2023 Category: Science Authors: Joel Snape Tags: Health & wellbeing Medical research Science Life and style Source Type: news
Patients with rare cancers given hope by UK-led ‘drug-match’ trial
Tumours reduce with treatment licensed for more common cancersLisa Park was 48 when she was admitted to A&E in 2019 with worsening bouts of abdominal pain. Her eventual diagnosis was unexpected. She was told she was suffering from gallbladder cancer, a rare but serious condition that usually only affects people in old age.Surgery and chemotherapy eradicated the tumours, but after a few months the cancer returned. “I was given a year to live,” said Park. It was a grim diagnosis, yet her prospects have recently taken an unexpected turn for the better.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 14, 2023 Category: Science Authors: Robin McKie Science Editor Tags: Cancer research Medical research Science Health Society University of Manchester UK news Source Type: news
Deprivation causes extra 33,000 UK cancer cases each year, analysis finds
Exclusive: Cancer Research UK says toll could be avoided if government tackled health inequalitiesHealth inequalities are causing 33,000 avoidable cases of cancer in the UK every year, a damning analysis suggests.Ministers have promised for years to tackle differences in health outcomes as part of their declared mission to level up the country. But their long-promised white paper on health inequalities has been ditched and thejunk food advertising ban on TV and the web has been delayed until October 2025.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 14, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Cancer Social exclusion Society UK news Health policy Politics Cancer research Smoking Obesity Medical research Source Type: news
Dementia risk factors pose more danger for ethnic minorities, finds study
Conditions such as diabetes and obesity are said to magnify risk of south Asian and black people developing the diseaseThe most common risk factors for dementia appear to have a more pronounced effect in black and Asian people, a study suggests, prompting calls for greater efforts to tackle health inequalities.The number of adults living with dementia worldwide is on course to nearly triple to 153 million by 2050. Experts say the disease presents a major and rapidly growing threat to future health and social care systems in every community, country and continent.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 11, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Dementia Alzheimer's Health Society UK news England Science Medical research Source Type: news
Monkey survives for two years with pig kidney in ‘extraordinary milestone’
Scientists say trial could pave way for better outcomes for ‘countless individuals’ in need of transplantsResearchers have claimed a major step forward in the field of organ transplantation after a monkey survived for more than two years with a genetically engineered pig kidney.The work is the latest to emerge from the US biotech company eGenesis and Harvard Medical School, where scientists see genetically altered pigs as a potential solution to the global shortage of donors for patients with organ failure.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 11, 2023 Category: Science Authors: Ian Sample and Anna Bawden Tags: Medical research Science Organ donation Society Health Genetics Biology Source Type: news
Mayo Clinic study sheds light on rare genetic disorder and blood cancers
In a recent study, Mayo Clinic researchers examined telomere biology disorders, a group of rare genetic disorders characterized by short telomeres. Telomeres are long segments at the end of chromosomes that protect the DNA from unraveling, similar to the small plastic sheath at the end of a shoelace. Telomeres shorten naturally with age but become abnormally shorter in telomere biology disorders. People with these disorders often have bone marrow failure and, for unknown reasons, a high… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 11, 2023 Category: Research Source Type: news
