Transcranial alternating current stimulation improves quality of life in Parkinson ’s disease: study protocol for a randomized, double-blind, controlled trial
The objective of this study is to investigate whether the addition of tACS to multidisciplinary intensive rehabilitation tr eatment (MIRT) can improve symptoms of PWP so as to enhance the quality of life in individuals with Parkinson’s disease based on the central-peripheral-central theory.MethodsThe present study was a randomized, double-blind trial that enrolled 60 individuals with Parkinson ’s disease aged between 45 and 70 years, who had Hoehn-Yahr scale scores ranging from 1 to 3. Participants were randomly assigned in a 1:1 ratio to either the tACS + MIRT group or the sham-tACS + MIRT group. The trial co...
Source: Trials - March 20, 2024 Category: Research Source Type: clinical trials

The Effect of Virtual Reality Application on Independence and Hand Functions in Daily Life in Children With CP
Conditions: Hemiplegic Cerebral Palsy Interventions: Other: ArmeoSenso; Other: Traditional Rehabilitation Sponsors: Hacettepe University; Ankara Bilkent City Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials

Group-based Cardiac Rehabilitation on Patients With Coronary Artery Bypass Graft Surgery
Conditions: Post-cardiac Surgery Interventions: Other: MICT with Aerobic exercise on treadmill; Other: standard hospital protocol Sponsors: Riphah International University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials

Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction
Conditions: Anterior Cruciate Ligament Reconstruction Interventions: Other: Rehabilitation training Sponsors: Linnaeus University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials

Verify the Performance in Clinical Practice of the Immersive Virtual Reality Platform GRAIL (Gait Real-time Analysis Interactive Lab)
Conditions: Acquired Brain Injury; Cerebral Palsy Interventions: Procedure: Physical Rehabilitation; Device: Gait Real-time Analysis Interactive Lab Sponsors: IRCCS Eugenio Medea Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials

The IMPROVE trial: study protocol for a pragmatic cluster randomised controlled trial to assess the effectiveness of using lay health workers to improve uptake and completion of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease
DiscussionImproving outcomes for chronic obstructive pulmonary disease and access to PR are priorities for the UK National Health Service (NHS) in its long-term plan. The trial hypothesis is that volunteer PR buddies, who are recruited and trained by local PR teams, are an effective and cost-effective way to improve the uptake and completion rates of PR. The trial is pragmatic, since it will test whether the intervention can be incorporated into NHS PR services. Information obtained in this trial may be used to influence policy on the use of PR buddies in PR and other similar services in the NHS.Trial registrationISRCTN126...
Source: Trials - March 19, 2024 Category: Research Source Type: clinical trials

Effectiveness of telerehabilitation intervention to improve pain and physical function in people with patellofemoral pain syndrome: study protocol for a randomized controlled trial
This study aims to investigate the non-inferiority of telerehabilitation through a smartphone application, theVito App, compared to face-to-face physical therapy on reducing pain and improving physical function, quality of life, and psychological factors.MethodsThis randomized controlled trial will include 60 PwPFPS. to a control group (face-to-face physical therapy) or an experimental group (telerehabilitation). The intervention for both groups consists of stretching, strengthening, balance, and functional exercises for 6  weeks and three sessions per week. The primary outcomes are pain intensity by visual analog scale (...
Source: Trials - March 19, 2024 Category: Research Source Type: clinical trials

Portable Mixed Reality-based Platform for Assessment of Progress in Multisensory Rehabilitation Strategies Post-TBI
Conditions: Brain Concussion; Vestibular Disorder; Cognition Disorder; Mild Traumatic Brain Injury Interventions: Device: Praxis; Behavioral: Supervised cardiovascular exercise Sponsors: BlueHalo; Brooke Army Medical Center; University of Pittsburgh Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials

Inspiratory Muscle Training in Burned Adults
Conditions: Burn Injuries Interventions: Other: inspiratory exercise; Other: Pulmonary rehabilitation Sponsors: Qassim University; Cairo University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials

Flexor Injury Rehabilitation Splint Trial (FIRST): protocol for a pragmatic randomised controlled trial comparing three splints for finger flexor tendon repairs
DiscussionFIRST will compare the three splints with respect to clinical efficacy, complications, quality of life and cost-effectiveness. FIRST is a pragmatic trial which will recruit from 26 NHS sites to allow findings to be generalisable to current clinical practice in the UK. It will also provide significant insights into patient experiences of splint wear and how adherence to splinting may impact outcomes.Trial registrationISRCTN: 10236011 (Source: Trials)
Source: Trials - March 16, 2024 Category: Research Source Type: clinical trials

Comprehensive Hybrid Cardiac Rehabilitation Trial on Heart Failure
Conditions: Heart Failure NYHA Class II; Heart Failure NYHA Class III Interventions: Other: Comprehensive Initial Assessment; Other: Continuous evaluation; Other: Interval Exercise; Behavioral: Psychosocial support; Other: Diet management; Other: Resistance exercise; Other: Continuous exercise; Other: Initial Assessment Sponsors: Universidad de La Frontera; University of Chile Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Effectiveness of Rehabilitation Protocol in Patients With Shortened Posterior Leg Muscles
Conditions: Equinus Deformity of Foot; Gastrocnemius Equinus; Contracture Interventions: Procedure: Specific protocol of rehabilitation exercise; Procedure: Short gastrocnemius surgery. Sponsors: Fundaci ón Universidad Católica de Valencia San Vicente Mártir Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials

Effectiveness of an eHealth Self-management Support Program for Persistent Pain After Breast Cancer Treatment
Conditions: Breast Cancer Interventions: Behavioral: eHealth self-management support program; Behavioral: Face-to-face rehabilitation program Sponsors: Universiteit Antwerpen; Universitaire Ziekenhuizen KU Leuven; University Ghent; KU Leuven; University Hospital, Antwerp Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials

Efficacy of a virtual reality-based cognitive interactive training program for children with traumatic brain injuries: study protocol for a parallel-group randomized controlled trial
DiscussionCognitive rehabilitation is among the top healthcare needs for pediatric TBI patients. Virtual reality-based training is promising due to its versatile content, flexibility, and potential cost savings for both patients and providers. Findings of this trial will provide data on the efficacy of the VICT program on core executive functions, attention problems, and health-related quality of life and serve as the empirical foundation for future larger multi-site effectiveness trials.Trial registrationClinicalTrials.govNCT04526639. Registered on August 18, 2020. (Source: Trials)
Source: Trials - March 13, 2024 Category: Research Source Type: clinical trials

The clinical effectiveness of a self-management intervention for patients with persistent depressive disorder and their partners/caregivers: results from a multicenter, pragmatic randomized controlled trial
ConclusionAlthough depressive symptoms did not improve relative to CAU, this only confirmed that treatment for patients with treatment-resistant PDD should move from symptom reduction to functional recovery. Also, functional recovery may be reflected in other outcomes than psychosocial burden, such as self-empowerment, in patients with treatment-resistant PDD. Future research on PPEP4All-PDD could focus on a longer-term program and/or online program that may also be offered earlier in the treatment process as an empowerment intervention.  Trial registrationNetherlands Trial Register Identifier NL5818. Registered on 20 Jul...
Source: Trials - March 13, 2024 Category: Research Source Type: clinical trials