Early Diagnosis of SSc in the General Rheumatology Clinic - Pilot
Conditions: Systemic Sclerosis; Raynaud Phenomenon Interventions: Device: Observation - Nailfold capillaroscopy Sponsors: University of Manchester; National Institute for Health Research, United Kingdom; Royal Bolton Hospital NHS Foundation Trust; Alder Hey Children ' s NHS Foundation Trust; University Hospitals of Morecambe Bay NHS Trust; Stockport NHS Foundation Trust; Medway NHS Foundation Trust; Northern Care Alliance NHS Foundation Trust; Royal Free Hospital NHS Foundation Trust Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials

Exploring the effects of a combined exercise programme on pain and fatigue outcomes in people with systemic sclerosis: study protocol for a large European multi-centre randomised controlled trial
DiscussionData from this multi-centre research clinical trial will primarily be used to establish the effectiveness of a combined exercise protocol to improve pain and fatigue in SSc. In parallel, this study will be the first to explore the effects of long-term exercise on potential microvascular alterations assessed via NVC. Overall, this study will provide sufficient data to inform current clinical practice guidelines and may lead to an improvement of QoL for patients with SSc.Trial registrationClinicalTrials.gov NCT05234671. Registered on 14 January 2022 (Source: Trials)
Source: Trials - November 28, 2022 Category: Research Source Type: clinical trials

Rheopheresis for Raynaud's and Digital Ulcers in Systemic Sclerosis
Conditions:   Systemic Sclerosis;   Raynaud Phenomenon;   Digital Ulcer;   Scleroderma Interventions:   Procedure: Rheopheresis treatment;   Drug: Intravenous Infusion Sponsors:   Peter Korsten;   DiaMed GmbH Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2022 Category: Research Source Type: clinical trials

Botulinum Toxin in Raynaud's Phenomenon
Condition:   Raynaud Phenomenon Intervention:   Drug: Botulinum toxin Sponsors:   Emory University;   American Society for Surgery of the Hand Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 18, 2021 Category: Research Source Type: clinical trials