Lonidamine Induced Selective Acidification and De-Energization of Prostate Cancer Xenografts: Enhanced Tumor Response to Radiation Therapy
Cancers (Basel). 2024 Mar 31;16(7):1384. doi: 10.3390/cancers16071384.ABSTRACTProstate cancer is a multi-focal disease that can be treated using surgery, radiation, androgen deprivation, and chemotherapy, depending on its presentation. Standard dose-escalated radiation therapy (RT) in the range of 70-80 Gray (GY) is a standard treatment option for prostate cancer. It could be used at different phases of the disease (e.g., as the only primary treatment when the cancer is confined to the prostate gland, combined with other therapies, or as an adjuvant treatment after surgery). Unfortunately, RT for prostate cancer is associa...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Stepan Orlovskiy Pradeep Kumar Gupta Jeffrey Roman Fernando Arias-Mendoza David S Nelson Cameron J Koch Vivek Narayan Mary E Putt Kavindra Nath Source Type: research
Association of Insomnia and Obstructive Sleep Apnea with Worse Oral Mucositis and Quality of Life in Head and Neck Cancer Patients Undergoing Radiation Therapy
CONCLUSION: Insomnia and OSA are highly prevalent in patients with HNC undergoing RT. These sleep disturbances are associated with worse QOL and OM during treatment.PMID:38611012 | DOI:10.3390/cancers16071335 (Source: Cancer Control)
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Austin J Iovoli Kelsey Smith Han Yu Melissa A Kluczynski Carla R Jungquist Andrew D Ray Mark K Farrugia Fangyi Gu Anurag K Singh Source Type: research
Accurate gamma-ray dose measurement up to 10 MeV by glass dosimeter with a sensitivity control filter for BNCT
In conclusion, the results of the standard sources showed the feasibility of this method, however for the volume source the dependence of the gamma-ray incident angle on the dosimeter was found to be not neglected. In the next step, it will be necessary to design a thinner filter in order to suppress the effect of the incident angle.PMID:38613949 | DOI:10.1016/j.apradiso.2024.111299 (Source: Applied Radiation and Isotopes)
Source: Applied Radiation and Isotopes - April 13, 2024 Category: Radiology Authors: F Kamisaki T Inoue K Tomiyoshi M Matsuki K Aoki S Kusaka S Tamaki F Sato I Murata Source Type: research
Prospective trial of Functional Lung Avoidance Radiation Therapy for Lung Cancer: Quality of Life Report
CONCLUSION: The current work provides an innovative combination of functional avoidance and PROs and is the first report of PROs for patients treated with prospective 4DCT-ventilation functional avoidance. Approximately 30% of patients had clinically significant decline in PROs at 12 months. The study provides additional data on outcomes with 4DCT-ventilation functional avoidance.PMID:38614278 | DOI:10.1016/j.ijrobp.2024.03.046 (Source: Health Physics)
Source: Health Physics - April 13, 2024 Category: Physics Authors: Joseph Lombardo Edward Castillo Richard Castillo Ryan Miller Bernard Jones Moyed Miften Brian Kavanagh Adam Dicker Cullen Boyle Benjamin Leiby Joshua Banks Nicole L Simone Benjamin Movsas Inga Grills Thomas Guerrero Chad G Rusthoven Yevgeniy Vinogradskiy Source Type: research
Diagnostic CT-Enabled Planning (DART): Results of a Randomized Trial in Palliative Radiation Therapy
CONCLUSION: dCT-based radiation planning substantially reduced TIC without detriment in plan deliverability or quality and had a tangible impact on patient experience with reduced patient-reported time burden.PMID:38613562 | DOI:10.1016/j.ijrobp.2024.03.005 (Source: Health Physics)
Source: Health Physics - April 13, 2024 Category: Physics Authors: Melissa O'Neil Joanna M Laba Timothy K Nguyen Michael Lock Christopher D Goodman Elizabeth Huynh Jonatan Snir Vikki Munro Jenna Alce Lidia Schrijver Sylvia Lemay Tara MacDonald Andrew Warner David A Palma Source Type: research
Prospective trial of Functional Lung Avoidance Radiation Therapy for Lung Cancer: Quality of Life Report
CONCLUSION: The current work provides an innovative combination of functional avoidance and PROs and is the first report of PROs for patients treated with prospective 4DCT-ventilation functional avoidance. Approximately 30% of patients had clinically significant decline in PROs at 12 months. The study provides additional data on outcomes with 4DCT-ventilation functional avoidance.PMID:38614278 | DOI:10.1016/j.ijrobp.2024.03.046 (Source: Health Physics)
Source: Health Physics - April 13, 2024 Category: Physics Authors: Joseph Lombardo Edward Castillo Richard Castillo Ryan Miller Bernard Jones Moyed Miften Brian Kavanagh Adam Dicker Cullen Boyle Benjamin Leiby Joshua Banks Nicole L Simone Benjamin Movsas Inga Grills Thomas Guerrero Chad G Rusthoven Yevgeniy Vinogradskiy Source Type: research
Diagnostic CT-Enabled Planning (DART): Results of a Randomized Trial in Palliative Radiation Therapy
CONCLUSION: dCT-based radiation planning substantially reduced TIC without detriment in plan deliverability or quality and had a tangible impact on patient experience with reduced patient-reported time burden.PMID:38613562 | DOI:10.1016/j.ijrobp.2024.03.005 (Source: Health Physics)
Source: Health Physics - April 13, 2024 Category: Physics Authors: Melissa O'Neil Joanna M Laba Timothy K Nguyen Michael Lock Christopher D Goodman Elizabeth Huynh Jonatan Snir Vikki Munro Jenna Alce Lidia Schrijver Sylvia Lemay Tara MacDonald Andrew Warner David A Palma Source Type: research
Accurate gamma-ray dose measurement up to 10 MeV by glass dosimeter with a sensitivity control filter for BNCT
In conclusion, the results of the standard sources showed the feasibility of this method, however for the volume source the dependence of the gamma-ray incident angle on the dosimeter was found to be not neglected. In the next step, it will be necessary to design a thinner filter in order to suppress the effect of the incident angle.PMID:38613949 | DOI:10.1016/j.apradiso.2024.111299 (Source: Applied Radiation and Isotopes)
Source: Applied Radiation and Isotopes - April 13, 2024 Category: Radiology Authors: F Kamisaki T Inoue K Tomiyoshi M Matsuki K Aoki S Kusaka S Tamaki F Sato I Murata Source Type: research
Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10 years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research
Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10 years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research
Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10 years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research
The effect of physical therapy and mechanical stimulation on dysfunction of lower extremities after total pelvic exenteration in cervical carcinoma patient with rectovesicovaginal fistula induced by radiotherapy: a case report
ConclusionStandardized physical therapy demonstrates the effect on postoperative complications after total pelvic exenteration and pelvic lymphadenectomy. This supports the necessity of multidisciplinary cooperation and early physiotherapy intervention. Further research is needed to determine the causes of thrombosis after standardized intervention, and more randomized controlled trials are needed to investigate the efficacy of physical therapy after total pelvic exenteration. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 13, 2024 Category: General Medicine Source Type: research
Fostering Transformation: Unleashing the Power of Artifical Intelligence and Machine Learning in the Field of Radiation Oncology
In conclusion, the article advocates for a proactive integration of AI and ML, envisioning a future where these technologies empower radiation oncologists to enhance patient care, optimize workflows, and advance the field. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 13, 2024 Category: ENT & OMF Source Type: research
Thoracic Proton Minibeam Radiation Therapy: Tissue Preservation and Survival Advantage over Conventional Proton Therapy.
This study assesses the potential advantages of pMBRT for thoracic irradiations compared to conventional radiotherapy in terms of normal tissue toxicity. The challenge here was the influence of respiratory motion on the typical peak and valley dose patterns of pMBRT and its potential biological impact. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - April 13, 2024 Category: Radiology Authors: Anna ïg Bertho, Ramon Ortiz, Mathieu Maurin, Marjorie Juchaux, Cristèle Gilbert, Julie Espenon, Gabriel Ramasamy, Annalisa Patriarca, Ludovic De Marzi, Frédéric Pouzoulet, Yolanda Prezado Tags: Biology Contribution Source Type: research
Impact of radiation therapy modalities on loco-regional control in inflammatory breast cancer
In inflammatory breast cancer (IBC), radiotherapy intensification is considered a standard of care by some teams, although the level of evidence remains low. We sought to analyze the impact of radiotherapy modalities on the risk of loco-regional and distant relapse. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - April 13, 2024 Category: Radiology Authors: Maximilien Rog é, Youlia Kirova, Emilie Lévêque, Marin Guigo, Alison Johnson, Rafik Nebbache, Eleonor Rivin del Campo, Ioana Lazarescu, Stéphanie Servagi, Augustin Mervoyer, Axel Cailleteau, Sébastien Thureau, Juliette Thariat Tags: Clinical Investigation Source Type: research
