Long-Term ERLEADA ® (apalutamide) Patient-Reported Outcomes Data in Metastatic Castration-Sensitive Prostate Cancer Demonstrate Maintenance of Health-Related Quality of Life for Patients
May 26, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced patient-reported outcomes (PRO) data from the pre-specified final analysis of the Phase 3 TITAN study in patients with metastatic castration-sensitive prostate cancer (mCSPC). The TITAN study previously demonstrated statistically significant improvement in overall survival (OS) after a median follow-up of 44 months in patients receiving ERLEADA® plus androgen deprivation therapy (ADT).1 The new PRO data showed that the addition of ERLEADA® to ADT maintained patients’ health-related quality of life (HRQoL) and ...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
MD Anderson Examines Aggressive Mesothelioma Surgery in Latest Study
A retrospective study involving two decades of pleural mesothelioma patients at the heralded University of Texas MD Anderson Cancer Center failed to demonstrate a definitive survival advantage to support regular use of extrapleural pneumonectomy surgery.
The most aggressive surgery possible for this type of mesothelioma – once the surgery of choice – showed no clear benefit over a more conservative procedure.
When compared to the less-aggressive, lung-sparing pleurectomy and decortication surgery, EPP had a much higher perioperative mortality rate and a shorter median survival.
“In comparison, we have not be...
Source: Asbestos and Mesothelioma News - May 25, 2021 Category: Environmental Health Authors: Fran Mannino Source Type: news
Hydrogen peroxide-producing drug boosts cancer-killing effect of radiotherapy
(University of Iowa Health Care) A small drug molecule that appears to protect normal tissue from the damaging effects of radiation, may simultaneously be able to boost the cancer-killing effect of radiation therapy, according to a new study led by scientists at University of Iowa, University of Texas Southwestern Medical Center, and Galera Therapeutics, Inc. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 13, 2021 Category: International Medicine & Public Health Source Type: news
PENTEC: World experts team up to improve outcomes for children after radiation therapy
(Children's Hospital Los Angeles) Experts around the world volunteer in a large-scale effort to provide the first evidence-based guidelines for pediatric radiation therapy. These guidelines are aimed at minimizing long-term side effects while maintaining effectiveness of therapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 12, 2021 Category: Cancer & Oncology Source Type: news
Study: Breast-conserving surgery offers better survival than mastectomy for cancer
Women who undergo breast-conserving surgery and radiation therapy for breast cancer are more likely to survive the disease than those who receive a full mastectomy, a study published Wednesday by JAMA Surgery found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 5, 2021 Category: Consumer Health News Source Type: news
New therapy shortens treatment for HPV-related cancers of the tonsils, tongue
Patients with HPV-related oropharyngeal cancer who undergo surgery and are treated with chemotherapy, may be able to forgo significant radiation therapy without increasing the risk of their cancer spreading, according to the results of a clinical trial led by researchers at Mayo Clinic. "We found that decreasing the amount of radiation therapy after a minimally invasive robotic [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 5, 2021 Category: Databases & Libraries Source Type: news
Mayo Clinic Q & amp;A podcast: Breast cancer radiotherapy and treatment innovations
The type of breast cancer a person has and how far it has spread determine the appropriate treatment. Previously, a patient with breast cancer might have received five to six weeks of radiation therapy. But the approach is changing. "For many years, we had the understanding that giving a little bit of radiation each day, [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 30, 2021 Category: Databases & Libraries Source Type: news
Can 3D-printed shields protect patients during radiation therapy?
3D-printed radioprotective shields produced from CT images can be used to protec...Read more on AuntMinnie.comRelated Reading:
Virtual surgical planning, 3D printing enhance maxillectomies
3D-printed surgical guides enhance breast conservation therapy
3D printing may help to uncover secrets of AAOCA
Ultralow-dose CT doesn't hurt value of 3D models
3D printing, AR can enhance thoracoscopic surgery (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 29, 2021 Category: Radiology Source Type: news
Accuray to tap Japanese market for ClearRT
Accuray has received Shonin approval from the Japanese Ministry of Health, Labou...Read more on AuntMinnie.comRelated Reading:
Accuray nets FDA nod for ClearRT imaging technology
Accuray's fiscal Q1 revenue declines
Accuray partners with Brainlab in radiation therapy
Accuray's Q4, fiscal year revenues decline
Accuray launches CyberKnife S7 system (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 22, 2021 Category: Radiology Source Type: news
Personalized, 3D printed shields developed to protect patients during radiation therapy
(Brigham and Women's Hospital) In a new paper published in Advanced Science, investigators from Brigham and Women's Hospital, Dana-Farber Cancer Institute, Massachusetts General Hospital and MIT describe efforts to develop a new personalized, 3D-printed device intended to shield patients who are undergoing radiation therapy and prevent radiation-induced toxicity. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 22, 2021 Category: Cancer & Oncology Source Type: news
Study finds stereotactic body radiotherapy is safe for treating multiple metastases
(University of Chicago Medical Center) In a phase 1 clinical trial to evaluate the safety of the approach, UChicago Medicine researchers found that high-powered, tightly-targeted radiation therapy is safe for treating patients with multiple metastases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 22, 2021 Category: Cancer & Oncology Source Type: news
Janssen Provides Update on Phase 3 ACIS Study in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ERLEADA ® (apalutamide) and ZYTIGA® (abiraterone acetate) Plus Prednisone Combination
RARITAN, N.J., April 19, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that regulatory submissions based on the Phase 3 ACIS study, which evaluated the combination of ERLEADA® (apalutamide) and ZYTIGA® (abiraterone acetate) plus prednisone in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC), will not be pursued. As presented at the American Society of Clinical Oncology’s Genitourinary (ASCO GU) Cancers Symposium in February 2021, the ACIS study met its primary endpoint of radiographic progression-free survival (rPFS); however, combination...
Source: Johnson and Johnson - April 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
RaySearch's new planning system treats 1st patients in Japan
RaySearch Laboratories said that its RayStation treatment planning system ha...Read more on AuntMinnie.comRelated Reading:
Canon Medical, RaySearch expand partnership
RaySearch, TAE Life Sciences partner on cancer therapy
RaySearch unveils new RayStation release
RaySearch, Varian partner to track radiation therapy
RaySearch inks Australian contract (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 16, 2021 Category: Radiology Source Type: news
Canon Medical, RaySearch expand partnership
Canon Medical Systems USA said it is expanding its partnership with RaySearc...Read more on AuntMinnie.comRelated Reading:
Canon nabs top award from IMV's ServiceTrak
Canon expands utility of AiCE in MRI
Sales of CT and x-ray help Canon 2020 results
RaySearch, TAE Life Sciences partner on cancer therapy
RaySearch unveils new RayStation release
RaySearch, Varian partner to track radiation therapy (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 15, 2021 Category: Radiology Source Type: news
Therapeutic Cancer Vaccine Shows Promise Against Multiple Tumor Types
TUESDAY, April 13, 2021 -- Marc Baum went through all the usual steps to treat his bladder cancer -- a couple of surgeries, radiation therapy and chemotherapy, all in a three-month period.
But doctors hope that an extra step -- an experimental... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 13, 2021 Category: General Medicine Source Type: news
