Long-term Neurovascular Complications After Radiation Therapy in Head and Neck Cancer
Conditions: Radiation Treatment; Neurovascular Complications Sponsors: Chang Gung Memorial Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 1, 2023 Category: Research Source Type: clinical trials
Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation
Conditions: Extensive Stage Lung Small Cell Carcinoma; Stage IV Lung Cancer Interventions: Drug: Carboplatin; Biological: Atezolizumab; Drug: Etoposide; Radiation: Total Body Irradiation; Radiation: Hypofractionated Radiation Therapy; Procedure: Magnetic Resonance Imaging Sponsors: Vanderbilt-Ingram Cancer Center; Genentech, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials
Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer
Conditions: Head and Neck Cancer; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck Interventions: Drug: Xevinapant; Drug: Carboplatin; Drug: Paclitaxel; Radiation: Radiation Therapy Sponsors: University of Chicago; EMD Serono Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials
Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients With Biochemically Recurrent Prostate Cancer
Conditions: Biochemically Recurrent Prostate Carcinoma; Prostate Adenocarcinoma Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Radiation: External Beam Radiation Therapy; Other: Flotufolastat F-18; Drug: Lutetium Lu 177 PSMA-10.1; Procedure: Positron Emission Tomography; Procedure: Single Photon Emission Computed Tomography Sponsors: Emory University; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials
Total Neoadjuvant Treatment for pMMR Locally Advanced Low Rectal Cancer: Anti-PD-1 Antibody With FOLFOXIRI and Preoperative Radiation Therapy
Conditions: Colorectal Cancer Interventions: Drug: Serplulimab + FOLFOXIRI; Radiation: Radiation therapy Sponsors: Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 25, 2023 Category: Research Source Type: clinical trials
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
Conditions: Breast Cancer; Axillary Nodal Disease; Female Breast Cancer; Axilla; Breast; Mastectomy; Lymphedema; Tumor, Breast Interventions: Procedure: Breast Surgery (BCS or mastectomy) with TAD/SNB and Adjuvant Radiation Therapy Sponsors: Alice Chung Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 20, 2023 Category: Research Source Type: clinical trials
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
Conditions: Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Oral Cavity Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Or...
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials
Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma
Conditions: Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Procedure: Endoscopic Ultrasound; Procedure: Esophagogastroduodenoscopy; Drug: Fluorouracil; Radiation: Hypofractionated Radiation Therapy; Drug: Leucovorin Calcium; Drug: Ox...
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
Conditions: Lung Cancer Interventions: Radiation: Hypofractionated accelerated radiation therapy Sponsors: Stanford University; LUNGevity Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort
Conditions: Breast Neoplasms; Radiation Pneumonia; Radiation Pneumonitis; Radiation Induced Fibrosis Interventions: Radiation: Radiation therapy protocol for Breast cancer; Diagnostic Test: Spirography and assessment of pulmonary diffusion capacity; Diagnostic Test: Cardiopulmonary stress test; Diagnostic Test: Computed tomography of the chest organs; Diagnostic Test: SF-36 Quality of Life Questionnaire; Diagnostic Test: Demographic and anthropometric measures; Other: Indicators characterizing the severity of the underlying disease Sponsors: Meshalkin Research Institute of Pathology of Circulation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
Conditions: Bone Metastases Interventions: Drug: Radiation Therapy Sponsors: M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials
Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Conditions: Prostate Adenocarcinoma; Stage II Prostate Cancer AJCC v8; Stage IIIA Prostate Cancer AJCC v8; Stage IIIB Prostate Cancer AJCC v8 Interventions: Drug: Apalutamide; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Radiation: MRI-guided Stereotactic Body Radiation Therapy; Procedure: Multiparametric Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Other: Questionnaire Administration Sponsors: Jonsson Comprehensive Cancer Center; Janssen Scientific Affairs, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials
A Study Using a New Drug, Nivolumab, in Combination With Chemotherapy Drugs to Treat a Type of Cancer Called Nasopharyngeal Carcinoma (NPC)
Conditions: Stage II Nasopharyngeal Carcinoma AJCC v8; Stage III Nasopharyngeal Carcinoma AJCC v8; Stage IV Nasopharyngeal Carcinoma AJCC v8 Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Chest Radiography; Drug: Cisplatin; Procedure: Computed Tomography; Procedure: Echocardiography; Other: Electronic Health Record Review; Other: Fluciclovine F18; Drug: Gemcitabine; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Biological: Nivolumab; Procedure: Positron Emission Tomography; Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Radiation: Ra...
Source: ClinicalTrials.gov - October 3, 2023 Category: Research Source Type: clinical trials
RCT of Intralesional Rituximab Injection Versus Involved Site Radiation Therapy in Ocular Adnexal MALT Lymphoma
Conditions: Primary Ocular Adnexal MALT Lymphoma Interventions: Drug: Rituximab; Radiation: Involved Site Radiation Therapy Sponsors: Zhongshan Ophthalmic Center, Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 3, 2023 Category: Research Source Type: clinical trials
Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)
Condition: Head and Neck Cancer Interventions: Drug: Xevinapant; Drug: Cisplatin; Radiation: intensity-modulated radiation therapy (IMRT) Sponsors: EMD Serono Research & Development Institute, Inc.; Merck KGaA, Darmstadt, Germany Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials
