IJERPH, Vol. 18, Pages 4017: Sleeping Duration, Napping and Snoring in Association with Diabetes Control among Patients with Diabetes in Qatar
Conclusions: our results suggest that napping may be an independent risk factor for a poor glycemic control in diabetes; further investigations are required. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 12, 2021 Category: Environmental Health Authors: Hiba Bawadi Asma Al Sada Noof Al Mansoori Sharifa Al Mannai Aya Hamdan Zumin Shi Abdelhamid Kerkadi Tags: Article Source Type: research

IJERPH, Vol. 18, Pages 4016: Emergency Medical Services (EMS) Transportation of Trauma Patients by Geographic Locations and In-Hospital Outcomes: Experience from Qatar
Conclusion: Within different areas in Qatar, the EMS response time and in-hospital outcomes were comparable. This indicates that the provision of prehospital care across the country is similar. The prehospital and acute in-hospital care are accessible for everyone in the country at no cost. Understanding the differences in EMS utilization and prehospital times contributes to the policy development in terms of equitable distribution of healthcare resources. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 12, 2021 Category: Environmental Health Authors: Hassan Al-Thani Ahammed Mekkodathil Attila J. Hertelendy Ian Howland Tim Frazier Ayman El-Menyar Tags: Article Source Type: research

Prevalence and risk factors for diabetic neuropathy and painful diabetic neuropathy in primary and secondary healthcare in Qatar
This study determined the prevalence and risk factors for diabetic peripheral neuropathy (DPN) and painful DPN (pDPN) in patients with type  2 diabetes in primary healthcare (PHC) and secondary healthcare (SHC) in Qatar.Materials and MethodsThis was a cross ‐sectional multicenter study. Adults with type 2 diabetes were randomly enrolled from four PHC centers and two diabetes centers in SHC in Qatar. Participants underwent assessment of clinical and metabolic parameters, DPN and pDPN.ResultsA total of 1,386 individuals with type  2 diabetes (297 from PHC and 1,089 from SHC) were recruited. The prevalence of...
Source: Journal of Diabetes Investigation - April 1, 2021 Category: Endocrinology Authors: Georgios Ponirakis, Tarik Elhadd, Subitha Chinnaiyan, Abdul H Hamza, Sanaulla Sheik, Mohamed A Kalathingal, Mohamed S Anodiyil, Zeinab Dabbous, Mashhood A Siddique, Hamad Almuhannadi, Ioannis N Petropoulos, Adnan Khan, Khaled AE Ashawesh, Kha Tags: Original Article Source Type: research

Herd Immunity against Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 10 Communities, Qatar
A. Jeremijenko et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - March 31, 2021 Category: Infectious Diseases Source Type: research

Serum Uric Acid Level Is Positively Associated With Higher Bone Mineral Density at Multiple Skeletal Sites Among Healthy Qataris
BackgroundOxidative stress has been implicated as a fundamental mechanism in the decline of bone mass. Although serum uric acid (SUA) has potent antioxidant properties, the findings of many epidemiological and experimental studies couldn’t draw a clear conclusion on the relation between SUA and bone health. We aim to investigate the association between SUA and bone mineral density (BMD) at different skeletal sites among healthy Qataris.MethodologyA cross-sectional analysis including total-body and site-specific bone mineral density scores and other serological markers of 2981 healthy Qatari adults (36.4 ± 11.1...
Source: Frontiers in Endocrinology - March 31, 2021 Category: Endocrinology Source Type: research

COVID-19 in the MENA Region: Facts and Findings
Conclusions: The unequal distribution of wealth among the MENA countries, the lack of sociopolitical stability, and the high number of undetected and underreported cases in some of them have resulted in varied incidences of COVID-19 related morbidity and mortality. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - March 30, 2021 Category: Infectious Diseases Source Type: research

Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis
ConclusionsThe observations assert significant microbial signatures of RVV, which is dose-dependent, and suggest manipulating these microbes as a novel approach for improving RVV efficacy. Further studies are warranted to investigate the immune status of these patients and mechanistic investigation to enhance RVV seroconversion. (Source: Gut Pathogens)
Source: Gut Pathogens - March 29, 2021 Category: Microbiology Source Type: research

Sensitization to Common Allergens Among Children with Asthma and Allergic Rhinitis in Qatar
(Source: Journal of Asthma and Allergy)
Source: Journal of Asthma and Allergy - March 28, 2021 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Viruses, Vol. 13, Pages 540: Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Conclusion: Our results indicated a relatively high seroprevalence of B19V in Qatar. Most importantly, B19 DNA was detected among Qatari and non-Qatari blood donors. Therefore, blood banks in Qatar might need to consider screening for B19V, especially when transfusion is intended for high-risk populations, including immunocompromised patients. (Source: Viruses)
Source: Viruses - March 24, 2021 Category: Virology Authors: Doua Abdelrahman Duaa W. Al-Sadeq Maria K. Smatti Sara A. Taleb Raed O AbuOdeh Enas S. Al-Absi Asmaa A. Al-Thani Peter. V. Coyle Nader Al-Dewik Ahmed A. Al Qahtani Hadi M. Yassine Gheyath K. Nasrallah Tags: Article Source Type: research

Corrigendum to “The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis” [Diabet. Res. Clin. Pract. 162 (2021) 108122]
The authors would like to acknowledge Open Access funding was provided by the Qatar National Library. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 22, 2021 Category: Endocrinology Authors: Hoda Gad, Hamad Al-Muhannadi, Hana Purra, Paul Mussleman, Rayaz A. Malik Tags: Corrigendum Source Type: research

Evaluating the impact of a brief Health at Every Size ®-informed health promotion activity on body positivity and internalized weight-based oppression
Body Image. 2021 Mar 18;37:225-237. doi: 10.1016/j.bodyim.2021.02.006. Online ahead of print.ABSTRACTWeight-based oppression, including negative attitudes about body weight, and harassment, stigma, and discrimination based on body weight, is a widespread phenomenon that leads to considerable distress and poor health and wellbeing outcomes. Conversely, body positivity is a multi-faceted concept that encompasses body acceptance, body appreciation, and body love, and adaptive approaches protective of health and wellbeing. The aim of this study was to evaluate the impact of a brief health promotion activity informed by Health ...
Source: Body Image - March 21, 2021 Category: Psychiatry & Psychology Authors: Lily O'Hara Hanaa Ahmed Sana Elashie Source Type: research

Evaluating the impact of a brief Health at Every Size ®-informed health promotion activity on body positivity and internalized weight-based oppression
Body Image. 2021 Mar 18;37:225-237. doi: 10.1016/j.bodyim.2021.02.006. Online ahead of print.ABSTRACTWeight-based oppression, including negative attitudes about body weight, and harassment, stigma, and discrimination based on body weight, is a widespread phenomenon that leads to considerable distress and poor health and wellbeing outcomes. Conversely, body positivity is a multi-faceted concept that encompasses body acceptance, body appreciation, and body love, and adaptive approaches protective of health and wellbeing. The aim of this study was to evaluate the impact of a brief health promotion activity informed by Health ...
Source: Body Image - March 21, 2021 Category: Psychiatry & Psychology Authors: Lily O'Hara Hanaa Ahmed Sana Elashie Source Type: research

Plasmodium vivax infection with exflagellated microgametes in peripheral blood smears
A 42-year-old man with travel history to Qatar and India was admitted for feverish sensation, headache and epigastric discomfort. Peripheral blood smears showed intraerythrocytic parasites compatible with Plasmodium vivax [Fig. 1 (a) and (b)]. Interestingly, some extra-erythropoietic parasites were also noted [Fig. 1 (c) –(f)]. The extra-erythropoietic parasites mimicked atypical spirochetes or non-malarial parasites such as trypanosomes, but were later identified as exflagellated microgametes of Plasmodium vivax. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 18, 2021 Category: Infectious Diseases Authors: Ting Hon Stanford Li, Andrew Chung Ho Lee, Wai Shan Wong, Yin Lan Yip Tags: Medical Imagery Source Type: research

IJERPH, Vol. 18, Pages 3093: Effects of COVID-19 Lockdown on Physical Activity, Sedentary Behavior, and Satisfaction with Life in Qatar: A Preliminary Study
In conclusion, COVID-19 confinement decreased PA, increased sitting time, and decreased life satisfaction in Qatar. These precautionary findings explicate the risk of psychosocial impairment and the potential physical harm of reducing physical activity during early COVID-19 confinement in 2020. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - March 17, 2021 Category: Environmental Health Authors: Souhail Hermassi Maha Sellami Ahmad Salman Abdulla S. Al-Mohannadi El Ghali Bouhafs Lawrence D. Hayes Ren é Schwesig Tags: Article Source Type: research

Quality of diabetes care in patients with schizophrenia: a case-control study in Qatar
Patients with schizophrenia are at least twice as likely to develop diabetes mellitus compared to the general population. This is of significance in Qatar given the high prevalence of obesity and diabetes. Fur... (Source: BMC Psychiatry)
Source: BMC Psychiatry - March 12, 2021 Category: Psychiatry Authors: Mustafa Abdul Karim, Nadeen Al-Baz, Sami Ouanes, Ali Khalil, Ahmed H. Assar, Abdulkarim Alsiddiqi, Zeinab Dabbous, Mahmoud Zirie, Peter Woodruff, Rayaz A. Malik and Peter M. Haddad Tags: Research article Source Type: research

Managing a patient with bipolar disorder associated with COVID ‐19: A case report from Qatar
Laboratory investigations AbstractThis case highlights an atypical presentation of a patient with unknown history of mental disease who has been diagnosed with a bipolar disorder associated with severe COVID ‐19 symptoms. Neuroimaging was only positive for subtle white matter changes; he was treated with antipsychotics and mood‐stabilizing agents until he reached partial remission. The authors urge clinicians to consider the impact of the COVID‐19 pandemic on patients with mental illness and the u rgent need for vigilant monitoring of presenting signs and symptoms. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 11, 2021 Category: General Medicine Authors: Mohamad Y. Khatib, Omer B. Mahgoub, Marwa Elzain, Amna A. Ahmed, Ahmed S. Mohamed, Abdulqadir J. Nashwan Tags: CASE REPORT Source Type: research

Preventing vector-borne diseases at major sport events: Addressing the challenges for FIFA 22 in Qatar
by Francis Schaffner, Devendra Bansal, Mohammed Hamad J. Al-Thani, Hamad Al-Romaihi, Elmoubasher Abu Baker Abd Farag (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 11, 2021 Category: Tropical Medicine Authors: Francis Schaffner Source Type: research

Diagnosis and management of X-linked hypophosphatemia in children and adolescent in the Gulf Cooperation Council countries
ConclusionThis guideline was developed to provide an approach to the diagnosis of XLH, especially where there is no family history of the disease, and that other related conditions are not mistaken for XLH. We also guide the medical management of XLH with conventional treatment and with burosumab, a recombinant human IgG1 monoclonal antibody to FGF23. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 4, 2021 Category: Orthopaedics Source Type: research

Burnout and job satisfaction among psychiatrists in the Mental Health Service, Hamad Medical Corporation, Qatar
CONCLUSIONS: The prevalence of high burnout in psychiatrists remains lower in Qatar than in other countries. Lower levels of satisfaction with co-workers, work, supervision, opportunities for promotion, and the job in general increased emotional exhaustion and depersonalization. Interestingly, satisfaction with salary did not have a significant effect on burnout.PMID:33657445 | DOI:10.1016/j.ajp.2021.102619 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - March 3, 2021 Category: Psychiatry Authors: Nisha Kader Bushra Elhusein Nahid M Elhassan Majid Alabdulla Samer Hammoudeh Nur-Run Hussein Source Type: research

Collaborative care model for diabetes in primary care settings in Qatar: a qualitative exploration among healthcare professionals and patients who experienced the service
Diabetes mellitus is highly prevalent and associated with huge economic burden globally. The conventional care and management of diabetes mellitus is highly fragmented and complex, warranting the need for a co... (Source: BMC Health Services Research)
Source: BMC Health Services Research - March 2, 2021 Category: General Medicine Authors: Sara Abdulrhim, Sowndramalingam Sankaralingam, Mohamed Izham Mohamed Ibrahim, Mohammed Issam Diab, Mohamed Abdelazim Mohamed Hussain, Hend Al Raey, Mohammed Thahir Ismail and Ahmed Awaisu Tags: Research article Source Type: research

Bioarchaeology-related studies in the Arabian Gulf: potentialities and shortcomings
Homo. 2021 Feb 23. doi: 10.1127/homo/2021/1282. Online ahead of print.ABSTRACTArchaeological studies provide a powerful tool to understand the prehistoric societies, especially when combined to cutting-edge morphological and molecular anthropological analyses, allowing reconstructing past population dynamics, admixture events, and socio-cultural changes. Despite the advances achieved in the last decades by archaeological studies worldwide, several regions of the World have been spared from this scientific improvement due to various reasons. The Arabian Gulf represents a unique ground to investigate, being the passageway fo...
Source: Homo - February 23, 2021 Category: Physiology Authors: Marica Baldoni Muna Al-Hashmi Alice Enrica Bianchi Ferhan Sakal Faisal Al-Naimi Thomas Leisten Cristina Mart ínez-Labarga Sara Tomei Source Type: research

Bioarchaeology-related studies in the Arabian Gulf: potentialities and shortcomings
Homo. 2021 Feb 23. doi: 10.1127/homo/2021/1282. Online ahead of print.ABSTRACTArchaeological studies provide a powerful tool to understand the prehistoric societies, especially when combined to cutting-edge morphological and molecular anthropological analyses, allowing reconstructing past population dynamics, admixture events, and socio-cultural changes. Despite the advances achieved in the last decades by archaeological studies worldwide, several regions of the World have been spared from this scientific improvement due to various reasons. The Arabian Gulf represents a unique ground to investigate, being the passageway fo...
Source: Homo - February 23, 2021 Category: Physiology Authors: Marica Baldoni Muna Al-Hashmi Alice Enrica Bianchi Ferhan Sakal Faisal Al-Naimi Thomas Leisten Cristina Mart ínez-Labarga Sara Tomei Source Type: research

Bioarchaeology-related studies in the Arabian Gulf: potentialities and shortcomings
Homo. 2021 Feb 23. doi: 10.1127/homo/2021/1282. Online ahead of print.ABSTRACTArchaeological studies provide a powerful tool to understand the prehistoric societies, especially when combined to cutting-edge morphological and molecular anthropological analyses, allowing reconstructing past population dynamics, admixture events, and socio-cultural changes. Despite the advances achieved in the last decades by archaeological studies worldwide, several regions of the World have been spared from this scientific improvement due to various reasons. The Arabian Gulf represents a unique ground to investigate, being the passageway fo...
Source: Homo - February 23, 2021 Category: Physiology Authors: Marica Baldoni Muna Al-Hashmi Alice Enrica Bianchi Ferhan Sakal Faisal Al-Naimi Thomas Leisten Cristina Mart ínez-Labarga Sara Tomei Source Type: research

Bioarchaeology-related studies in the Arabian Gulf: potentialities and shortcomings
Homo. 2021 Feb 23. doi: 10.1127/homo/2021/1282. Online ahead of print.ABSTRACTArchaeological studies provide a powerful tool to understand the prehistoric societies, especially when combined to cutting-edge morphological and molecular anthropological analyses, allowing reconstructing past population dynamics, admixture events, and socio-cultural changes. Despite the advances achieved in the last decades by archaeological studies worldwide, several regions of the World have been spared from this scientific improvement due to various reasons. The Arabian Gulf represents a unique ground to investigate, being the passageway fo...
Source: Homo - February 23, 2021 Category: Physiology Authors: Marica Baldoni Muna Al-Hashmi Alice Enrica Bianchi Ferhan Sakal Faisal Al-Naimi Thomas Leisten Cristina Mart ínez-Labarga Sara Tomei Source Type: research

Bioarchaeology-related studies in the Arabian Gulf: potentialities and shortcomings
Homo. 2021 Feb 23. doi: 10.1127/homo/2021/1282. Online ahead of print.ABSTRACTArchaeological studies provide a powerful tool to understand the prehistoric societies, especially when combined to cutting-edge morphological and molecular anthropological analyses, allowing reconstructing past population dynamics, admixture events, and socio-cultural changes. Despite the advances achieved in the last decades by archaeological studies worldwide, several regions of the World have been spared from this scientific improvement due to various reasons. The Arabian Gulf represents a unique ground to investigate, being the passageway fo...
Source: Homo - February 23, 2021 Category: Physiology Authors: Marica Baldoni Muna Al-Hashmi Alice Enrica Bianchi Ferhan Sakal Faisal Al-Naimi Thomas Leisten Cristina Mart ínez-Labarga Sara Tomei Source Type: research

Bioarchaeology-related studies in the Arabian Gulf: potentialities and shortcomings
Homo. 2021 Feb 23. doi: 10.1127/homo/2021/1282. Online ahead of print.ABSTRACTArchaeological studies provide a powerful tool to understand the prehistoric societies, especially when combined to cutting-edge morphological and molecular anthropological analyses, allowing reconstructing past population dynamics, admixture events, and socio-cultural changes. Despite the advances achieved in the last decades by archaeological studies worldwide, several regions of the World have been spared from this scientific improvement due to various reasons. The Arabian Gulf represents a unique ground to investigate, being the passageway fo...
Source: Homo - February 23, 2021 Category: Physiology Authors: Marica Baldoni Muna Al-Hashmi Alice Enrica Bianchi Ferhan Sakal Faisal Al-Naimi Thomas Leisten Cristina Mart ínez-Labarga Sara Tomei Source Type: research

National assessment of pharmaceutical workforce and education using the International Pharmaceutical Federation ’s global development goals: a case study of Qatar
ConclusionThe results indicated that DG[w]s are interrelated and a gap in one goal can negatively influence others. Results and recommendations of this research will facilitate the implementation of strategic plans across leading pharmacy sectors to meet health needs in Qatar and achieve the third pillar of the Qatar National Vision 2030. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - February 22, 2021 Category: Pharmaceuticals Source Type: research

Prevalence, median time, and associated factors with the likelihood of initial antidepressant change: a cross-sectional study in Qatar
Major Depressive Disorder (MDD) requires therapeutic interventions during the initial month after being diagnosed for better disease outcomes. International guidelines recommend a duration of 4 –12 weeks for an... (Source: BMC Psychiatry)
Source: BMC Psychiatry - February 22, 2021 Category: Psychiatry Authors: Nervana Elbakary, Sami Ouanes, Sadaf Riaz, Oraib Abdallah, Islam Mahran, Noriya Al-Khuzaei and Yassin Eltorki Tags: Research article Source Type: research

Nurses ’ willingness to work with COVID‐19 patients: The role of knowledge and attitude
This study aims to assess the role of nurses ’ knowledge and attitude in relation to their willingness to work with patients diagnosed with COVID‐19 in Qatar.DesignA cross ‐sectional study.MethodsA self ‐administered, 35‐item online survey was circulated to the Registered Nurses working in Hamad Medical Corporation, the principal healthcare provider in Qatar.ResultsA total of 580 attempts to complete the survey. Of them, 377 completed surveys with a response rate of 65%. Logistic regression was used to predict nurses ’ willingness to work with patients with COVID‐19. Nurses’ knowledge level and ...
Source: Nursing Open - February 11, 2021 Category: Nursing Authors: Abdulqadir J. Nashwan, Ahmad A. Abujaber, Ahmed S. Mohamed, Ralph C. Villar, Mahmood M. Al ‐Jabry Tags: RESEARCH ARTICLE Source Type: research

Establishing comprehensive forensic mental health services in Qatar.
Authors: Alabdulla M, Reagu SM, Tulley I Abstract Qatar has experienced exponential economic and healthcare infrastructural development recently. Mental health has been prioritized for development by the state with the launching of the ambitious National Mental Health Strategy in 2013 which incorporates the development of specialist Forensic psychiatry services. Traditionally, some aspects of forensic psychiatry care were provided under general psychiatry, being largely reactive. The new strategy supported the development of specialist Forensic service with a focus on developing safer communities, preventing victim...
Source: Asian Journal of Psychiatry - February 10, 2021 Category: Psychiatry Tags: Asian J Psychiatr Source Type: research

Biosafety Level 2 cabinet UV ‐C light exposure of sports antidoping human urine samples does not affect the stability of selected prohibited substances
studied in samples with and without irradiation. The UV‐C irradiation is degrading DNA/RNA and coronaviruses. The biosafety Level 2 cabinet use has been recommended by WADA. AbstractThe current study examined the stability of several antidoping prohibited substances analytes in urine after 15 ‐min exposure to UV‐C light in a Biosafety Level 2 cabinet. The urine matrices were exposed within the original antidoping bottles with the aim to destroy DNA/RNA and possible SARS CoV‐2. The analytes small molecules Phase I and Phase II metabolites and peptides, in total 444, endogenous, inte rnal standards, and prohibited s...
Source: Drug Testing and Analysis - February 10, 2021 Category: Drugs & Pharmacology Authors: Sven Voss, Wadha Abushreeda, Ariadni Vonaparti, Aisha Al ‐Wahaibi, Noora Al‐Sowaidi, Ibrahim Al‐Mohannadi, Souhila Mahieddine, Safa Khelifi, Sofia Salama, Amal Saleh, Maryam Al‐Mohannadi, Wesal El‐Saftawy, Khalifa Al‐Hamad, Ahmad Tags: SHORT COMMUNICATION Source Type: research

Prevalence and associated factors of DSM-5 insomnia disorder in the general population of Qatar
Epidemiological studies of insomnia in the Middle East remain scarce. The present study aimed to estimate the prevalence of insomnia and explore its associations in the general population of Qatar. With almost... (Source: BMC Psychiatry)
Source: BMC Psychiatry - February 8, 2021 Category: Psychiatry Authors: Salma Mawfek Khaled, Catalina Petcu, Maryam Ali Al-Thani, Aisha Mohammed H. A. Al-Hamadi, Suhad Daher-Nashif, Monica Zolezzi and Peter Woodruff Tags: Research article Source Type: research

Eradication of hepatitis C virus infection in kidney transplant recipients using direct ‐acting antiviral therapy: Qatar experience
ConclusionsHCV infection was successfully eradicated by DAA therapy in kidney transplant recipients, with a 100% SVR rate. Moreover, DAA therapy was well ‐tolerated, and kidney function remained stable without an increased risk of rejection. These results are expected to drive the eradication of hepatitis C from the entire country. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 4, 2021 Category: Allergy & Immunology Authors: Mohamad M. Alkadi, Essa A. Abuhelaiqa, Mostafa F. Elshirbeny, Ahmed F. Hamdi, Omar M. Fituri, Muhammad Asim, Saad R. Alkaabi, Moutaz F. Derbala, Mona E. Jarman, Adel M. Ashour, Awais Nauman, Yousuf K. Al Maslamani, Adeel A. Butt, Hassan A. Al Tags: ORIGINAL RESEARCH Source Type: research

Veolia upgrades wastewater treatment facility on a dairy farm in Qatar
Publication date: January 2021Source: Membrane Technology, Volume 2021, Issue 1Author(s): (Source: Membrane Technology)
Source: Membrane Technology - February 2, 2021 Category: Materials Science Source Type: research

Major histocompatibility complex (MHC) associations with diseases in ethnic groups of the Arabian Peninsula
AbstractSince the discovery of human leukocyte antigens (HLAs), the function of major histocompatibility complex (MHC) gene families in a wide range of diseases have been the subject of research for decades. In particular, the associations of autoimmune disorders to allelic variants and candidate genes encoding the MHC are well documented. However, despite decades of research, the knowledge of MHC associations with human disease susceptibility have been predominantly studied in European origin, with limited understanding in different populations and ethnic groups. This is particularly evident in countries and ethnic popula...
Source: Immunogenetics - February 2, 2021 Category: Genetics & Stem Cells Source Type: research

Association between periodontitis and severity of COVID-19 infection: a case-control study.
CONCLUSION: Periodontitis was associated with higher risk of ICU admission, need for assisted ventilation and death of COVID-19 patients, and with increased blood levels of biomarkers linked to worse disease outcomes. PMID: 33527378 [PubMed - as supplied by publisher] (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - February 1, 2021 Category: Dentistry Authors: Marouf N, Cai W, Said KN, Daas H, Diab H, Chinta VR, Hssain AA, Nicolau B, Sanz M, Tamimi F Tags: J Clin Periodontol Source Type: research

Short- and long-term cost-effectiveness of CYP2C19 genotype-guided therapy, universal clopidogrel, and universal ticagrelor in post-percutaneous coronary intervention patients in Qatar
Patients having CYP2C19 loss-of-function alleles and receiving clopidogrel are at higher risk of adverse cardiovascular outcomes. Ticagrelor is an effective antiplatelet that is unaffected by the CYP2C19 polymorphism. The main aim of the current research is to evaluate the cost-effectiveness among CYP2C19 genotype-guided therapy, universal ticagrelor, and universal clopidogrel after a percutaneous coronary intervention (PCI). (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - January 31, 2021 Category: Cardiology Authors: Sawsan AlMukdad, Hazem Elewa, Salaheddin Arafa, Daoud Al-Badriyeh Source Type: research

Short- and long-term cost-effectiveness analysis of CYP2C19 genotype-guided therapy, universal clopidogrel, versus universal ticagrelor in post-percutaneous coronary intervention patients in Qatar
Patients having CYP2C19 loss-of-function alleles and receiving clopidogrel are at higher risk of adverse cardiovascular outcomes. Ticagrelor is an effective antiplatelet that is unaffected by the CYP2C19 polymorphism. The main aim of the current research is to evaluate the cost-effectiveness among CYP2C19 genotype-guided therapy, universal ticagrelor, and universal clopidogrel after a percutaneous coronary intervention (PCI). (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - January 31, 2021 Category: Cardiology Authors: Sawsan AlMukdad, Hazem Elewa, Salaheddin Arafa, Daoud Al-Badriyeh Source Type: research

Evidence of community pharmacists ’ response preparedness during COVID-19 public health crisis: A cross-sectional study
Conclusions: Community pharmacists in Qatar are willing to receive additional training related to COVID-19 public health crisis despite being prepared to engage with patients. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - January 31, 2021 Category: Infectious Diseases Source Type: research

Perceived Barriers to Colorectal Cancer Screening among Eligible Adults in Qatar and Its Predictors: A Cross-Sectional Study.
CONCLUSION: The present study identified several barriers to undergoing CRC screening among eligible adults in Qatar. Such results provide a basis for tailoring of future educational campaigns that are relevant, specific, and appealing to such a cohort.. PMID: 33507678 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - January 30, 2021 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Socio-demographic influences on the prevalence of intestinal parasitic infections among workers in Qatar
The rapid growth of Qatar in the last two decades has been associated with an enormous expansion of building programs in its cities and in the provision of new service industries. This in turn has attracted a ... (Source: Parasites and Vectors)
Source: Parasites and Vectors - January 20, 2021 Category: Microbiology Authors: Nadin Younes, Jerzy M. Behnke, Ahmed Ismail and Marawan A. Abu-Madi Tags: Research Source Type: research

Voice and Emphasis in Arabic Coronal Stops: Evidence for Phonological Compensation.
Abstract The current study investigates multiple acoustic cues-voice onset time (VOT), spectral center of gravity (SCG) of burst, pitch (F0), and frequencies of the first (F1) and second (F2) formants at vowel onset-associated with phonological contrasts of voicing and emphasis in production of Arabic coronal stops. The analysis of the acoustic data collected from eight native speakers of the Qatari dialect showed that the three stops form three distinct modes on the VOT scale: [d] is (pre)voiced, voiceless [t] is aspirated, and emphatic [ṭ] is voiceless unaspirated. The contrast is also maintained in spectral c...
Source: Language and Speech - January 18, 2021 Category: Speech-Language Pathology Authors: Kulikov V Tags: Lang Speech Source Type: research

Proceedings From the First International Workshop at Sidra Medicine: “Engineered Immune Cells in Cancer Immunotherapy (EICCI): From Discovery to Off-the-Shelf Development”, 15th–16th February 2019, Doha, Qatar
The progress in the isolation and characterization of tumor antigen (TA)-specific T lymphocytes and in the genetic modification of immune cells allowed the clinical development of adoptive cell therapy (ACT). Several clinical studies highlighted the striking clinical activity of T cells engineered to express either Chimeric Antigen (CAR) or T Cell (TCR) Receptors to target molecularly defined antigens expressed on tumor cells. The breakthrough of immunotherapy is represented by the approval of CAR-T cells specific for advanced or refractory CD19+ B cell malignancies by both the Food and Drug Administration (FDA) and the Eu...
Source: Frontiers in Immunology - January 14, 2021 Category: Allergy & Immunology Source Type: research

Cost-effectiveness of Oral Versus Intravenous Ibuprofen Therapy in Preterm Infants With Patent Ductus Arteriosus in the Neonatal Intensive Care Setting: A Cohort-based Study.
This study aimed to evaluate the clinical and economic impact of oral ibuprofen versus intravenous ibuprofen for PDA among preterm infants. METHODS: This retrospective, cohort-based pilot study examined the clinical and economic associations of oral versus intravenous ibuprofen for PDA. A decision-analytic model was constructed, from the hospital perspective, to follow the oral versus intravenous administrations of ibuprofen for PDA and their clinical and economic consequences. The course regimen of either formulation was an initial 10 mg/kg followed by 5 mg/kg at 24- and 48-h intervals. Clinical and resourc...
Source: Clinical Therapeutics - January 8, 2021 Category: Drugs & Pharmacology Authors: Abushanab D, Rouf PA, Al Hail M, Kamal R, Viswanathan B, Parappil H, Elkassem W, Al-Shaibi S, Al-Badriyeh D Tags: Clin Ther Source Type: research

Breast Cancer Screening Practices in a Tertiary Care Center in the State of Qatar: A Cross-Sectional Survey
(Source: Vascular Health and Risk Management)
Source: Vascular Health and Risk Management - January 7, 2021 Category: Cardiology Tags: Breast Cancer: Targets and Therapy Source Type: research

Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar
AbstractAcute gastroenteritis (AGE) remains a major cause of diarrhea in developing and developed countries. Rotavirus (RV) is a leading cause of severe pediatric diarrhea worldwide. Here we report on the prevalence of circulating genotypes in association with demographics and clinical manifestations outcomes in Qatar. A total of 231 RV-positive fecal samples were collected from children suffering from AGE during 3  years study period between June 2016 and June 2019. The age of the subjects ranged between 2 months and 14 years (median of 16 months). The VP4 and VP7 were amplified and sequenced. Phylogen...
Source: European Journal of Clinical Microbiology and Infectious Diseases - January 7, 2021 Category: Microbiology Source Type: research