Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)
Conditions: Posttraumatic Stress Disorder Interventions: Drug: Ketamine; Device: SmartSleep EEG recording headband Sponsors: University of Wisconsin, Madison Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
The translocator protein 18kDa ligand etifoxine in the treatment of depressive disorders —a double-blind, randomized, placebo-controlled proof-of-concept study
This study will provide a first proof-of-concept on the potential of the TSPO ligand etifoxine in the treatment of depressive disorders.Trial registrationClinical Trials Register (EudraCT number:2021-006773-38, registration date: 14 September 2022) and German Register of Clinical Studies (DRKS number:DRKS00031099, registration date: 23 January 2023). (Source: Trials)
Source: Trials - April 22, 2024 Category: Research Source Type: clinical trials
Prospective evaluation of blood biomarkers as an aid to diagnostic and treatment in drug-naive patients with depression
Conditions: Depressive Disorder; Bipolar Disorder; Bipolar Depression Sponsors: Les Toises - Psychiatry and Psychotherapy Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
Evaluation of blood biomarker-based diagnostic aid in outpatients suffering from depression
Conditions: Depressive Disorder; Bipolar Disorder; Bipolar Depression Interventions: Other: there is no intervention Sponsors: Les Toises - Psychiatry and Psychotherapy Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
Combination of Neurostimulation and Psychotherapy to Stop Worrying
Conditions: Active tDCS; Sham tDCS Interventions: Device: Active tDCS; Device: Sham tDCS Sponsors: University Hospital, Ghent Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
Development and Initial Application of a Combined Exercise and Psychological Intervention Program for Patients After Esophagectomy
Conditions: Esophageal Cancer; Exercise Training; Psychotherapy; Rehabilitation Interventions: Behavioral: Exercise and Psychological Intervention Sponsors: Mengmeng Yuan; Anhui Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
Schema therapy versus treatment as usual for outpatients with difficult-to-treat depression: study protocol for a parallel group randomized clinical trial (DEPRE-ST)
DiscussionThis trial will provide evidence on the beneficial and harmful effects, as well as the cost-effectiveness of schema therapy versus treatment as usual for outpatients with difficult-to-treat depression. The results can potentially improve treatment for a large and understudied patient group.Trial registrationClinicalTrials.gov NCT05833087. Registered on 15th April 2023 (approved without prompts for revision on 27th April 2023). (Source: Trials)
Source: Trials - April 16, 2024 Category: Research Source Type: clinical trials
MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents
Conditions: PTSD, Post Traumatic Stress Disorder; Adolescents; Psychotherapy Interventions: Drug: MDMA; Behavioral: Psychotherapy Sponsors: University of California, Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
An Intervention Study Based on Digital AI Psychotherapy
Conditions: LLM-based AI Conversational Agents; Mental Health; Depression; Anxiety; Youth Interventions: Other: AI conversation intervention; Other: Waiting group Sponsors: Institute of Psychology, Chinese Academy of Sciences Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
The Predictive Role of Immune-inflammatory Biomarkers and Their Interaction With the Oxytocin System in Trauma-related Psychotherapy Responsiveness
Conditions: Posttraumatic Stress Disorder Sponsors: Shalvata Mental Health Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
Increasing Access to Evidence-Based Care in Integrated Behavioral Health
Conditions: Psychotherapy Interventions: Behavioral: Therapy Session Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
VR Augmented Human Delivered Integrative Psychotherapy for Colonoscopy Procedural Anxiety and Pain
Conditions: Procedural Anxiety; Procedural Pain Interventions: Behavioral: Virtual Reality Integrative Psychotherapy; Device: Virtual Reality Distraction Sponsors: Grigore T. Popa University of Medicine and Pharmacy; Romanian Academy Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials
Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin
Conditions: Major Depressive Disorder; Depression; Treatment-Resistant Depression; Mood Disorders Interventions: Drug: Single Psychedelic Dose Psilocybin; Drug: Two Psychedelic Doses Psilocybin Sponsors: University Health Network, Toronto; Centre for Addiction and Mental Health Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials
Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya —individually randomised superiority trial
This study seeks to gauge the potency of g-IPT for women with PND in two LMICs.MethodsThis multi-site randomised controlled trial is a continuation of two preceding phases —conceptual mapping and a feasibility study executed in Lebanon and Kenya. Insights gleaned from these phases underpin this comprehensive RCT, which contrasts the efficacy and cost-effectiveness of high-quality standard care (HQ-SC) augmented with g-IPT against HQ-SC in isolation. The trial, chara cterised as an individually randomised superiority assessment, targets women with postnatal depression in Beirut, Lebanon, and Nairobi, Kenya. It aims to det...
Source: Trials - March 26, 2024 Category: Research Source Type: clinical trials
A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer
Conditions: Caregiver Burden; Caregiver Burnout; Caregiver Stress Syndrome Interventions: Behavioral: Meaning-Centered Psychotherapy for Caregivers; Behavioral: Supportive Psychotherapy for Caregivers Sponsors: Memorial Sloan Kettering Cancer Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
